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Acute low-intensity microwave exposure increases DNA single-Strand breaks in rat brain cells

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Levels of DNA single-strand break were assayed in brain cells from rats acutely exposed to low-intensity 2450 MHz microwaves using an alkaline microgel electrophoresis method. Immediately after 2 h of exposure to pulsed (2 microseconds width, 500 pulses/s) microwaves, no significant effect was observed, whereas a dose rate-dependent [0.6 and 1.2 W/kg whole body specific absorption rate (SAR)] increase in DNA single-strand breaks was found in brain cells of rats at 4 h postexposure. Furthermore, in rats exposed for 2 h to continuous-wave 2450 MHz microwaves (SAR 1.2 W/kg), increases in brain cell DNA single-strand breaks were observed immediately as well as at 4 h postexposure.
... We shall name it 'Bioactivity of the EMF' or 'EMF-Bioactivity'. Thus: (11) where @ 4×10 -9 C·s/kg is a constant quantity (depending upon the membrane electric field E m and the velocity of the ion through an open channel u o ), E o is the intensity amplitude and ν is the frequency of the applied electric field. We shall name k the 'bioactivity constant'. ...
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... Several studies have indicated that 2450MHz MW radiation can induce genotoxic effects and triggered apoptosis. 27,[36][37][38][39] It has been found that the expression level of P53 has increased noticeably in resistant cells receiving combined therapy although this value is still less than sensitive cells. This indicates that MWs can significantly increase the sensitivity of resistant ovarian cancer cells. ...
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... Note the intact seminiferous tubules in (A), and the degenerated seminiferous tubules in (B) (arrow). Hematoxylin and Eosin [40][41][42][43][44][45][46][47][48][49][50][51][52]. ...
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