Heterogeneity of hematopoietic stem cells

ArticleinCurrent Opinion in Immunology 5(2):177-84 · May 1993with2 Reads
Impact Factor: 7.48 · DOI: 10.1016/0952-7915(93)90002-A · Source: PubMed


    Hematopoietic stem cells are capable of multi-lineage differentiation to all blood cell types as well as self-renewal and radioprotection. Thy-1.1lo Lin-/lo Sca-1+ cells are a heterogeneous mixture of quiescent and self-renewing hematopoietic stem cells as well as multi-lineage expanding cells.