Assignment of the Human GTF2F1 Gene to Chromosome 19p13.3

ArticleinGenomics 16(1):252-3 · May 1993with4 Reads
Impact Factor: 2.28 · DOI: 10.1006/geno.1993.1168 · Source: PubMed


    TFIIF (also termed FC) is a general transcription initiation factor that binds to RNA polymerase II and recruits it to a promoter. TFIIF is a heterodimer composed of 74-kDa (RAP74; gene symbol GTF2F1) and 30-kDa (RAP30; gene symbol GTF2F2) subunits. Here we report the mapping of the human GTF2F1 gene to band 19p13.3. Localization was performed by fluorescence in situ hybridization using the human RAP74 genomic cosmid clone as the probe.