Article

Factors that affect social cue recognition in schizophrenia

University of Chicago Center for Psychiatric Rehabilitation, Tinley Park, IL 60477, USA.
Psychiatry Research (Impact Factor: 2.47). 06/1998; 78(3):189-96. DOI: 10.1016/S0165-1781(98)00013-4
Source: PubMed

ABSTRACT

Earlier research (Corrigan and Green, Am. J. Psychiatry, 150 (1993) 589-594) showed fairly symptomatic persons with schizophrenia give more false-positive responses when answering questions about abstract cues in a social situation (i.e. affect, rules, and goals inferred about an interpersonal situation) than concrete cues (i.e. actions and dialogue observed in a situation). It is unclear, however, whether differential cue recognition is due to schizophrenia per se, or some aspect of the illness commensurate with significant symptoms and in-patient care. Moreover, the abstract and concrete dimension in the earlier study had not been independently validated. In this study, the 288 items of the Social Cue Recognition Test (SCRT) were divided into three sets based on abstraction ratings provided by 38 college students. The SCRT was then completed by 48 participants with DSM-III-R diagnoses of schizophrenia or schizoaffective disorder. Participants with schizophrenia were divided into low and high symptom groups using scores from the Brief Psychiatric Rating Scale. Results showed both low symptom and high symptom groups exhibited a differential deficit in cue recognition. False positives were greater for items rated as more abstract. Implications for understanding the social cognitive deficits of persons with schizophrenia are discussed.

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    • "All participants were also interviewed by a neuropsychologist. Premorbid IQ was estimated with the National Adult Reading Test (Corrigan and Nelson, 1998), and current IQ with the Wechsler Abbreviated Scale of Intelligence (Wechsler, 1999). Sustained attention was measured using a computerized continuous performance test (CPT) (Birkett et al., 2007), and frontal executive function with the Trail Making Test (Reitan, 1958). "
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    Full-text · Article · Mar 2015 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
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    • "Failure of inhibitory control, e.g., using the prepulse inhibition paradigm, has been proposed as one of the key endophenotypes of schizophrenia (SZ) (Cadenhead et al., 2002). Individuals with SZ have difficulty overcoming prepotent response tendencies (Ford et al., 2004), and some inhibitory paradigms using explicit predictive cues have demonstrated longer reaction times (RTs) and more errors in SZ subjects than in healthy comparison subjects (HC) (Fallgatter et al., 2003; Fallgatter and Muller, 2001; Fallgatter, 2001; Javitt et al., 2000).Other studies have found that SZ subjects present impaired cue recognition in a social context (Corrigan and Nelson, 1998; Ito et al., 1998; Hall et al., 2004), particularly in those with positive symptoms (Hall et al., 2004; Crider, 1997). "
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    ABSTRACT: The primary purpose of this investigation was to assess the neural correlates of implicit cueing during an inhibitory task in schizophrenia when performance accuracy was matched with healthy comparison subjects. We compared 17 individuals with chronic schizophrenia (SZ; medicated, 13.9 average years of illness) and 17 healthy comparison subjects (HC) matched for hit and false alarm rates, age, and education on a visual Go/Nogo task during functional magnetic resonance imaging. In this task, one of the go stimuli also served implicitly as a cue predictive of a subsequent inhibitory (Nogo) trial. Findings suggest that even when matched for overall performance accuracy, individuals with SZ exhibit difficulties with inhibition and cue processing that may relate to core deficits in cognitive control and stimulus processing. In particular, these findings point towards an important role of the parietal cortex for cued inhibitory processes in healthy populations.
    Full-text · Article · Sep 2006 · NeuroImage
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    • "One factor that leads to this deficit is miscommunication with others. For example, patients may misidentify social information (rules, affect and goals in social situations) especially when asked abstract, rather than concrete, questions about social situations (Corrigan & Green, 1993; Corrigan & Nelson, 1998). Some current models of schizophrenia postulate that it can be best understood as a disorder of the representation of mental states (i.e. the inability to represent what others are thinking) (Frith, 1992 ; Broks, 1997). "
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