A new strong inhibitor of beta-mannosidase

ArticleinBioorganic & Medicinal Chemistry Letters 8(4):371-2 · March 1998with3 Reads
Impact Factor: 2.42 · DOI: 10.1016/S0960-894X(98)00031-6 · Source: PubMed

    Abstract

    N-phenyl-carbamate of D-mannonohydroxymolactone (I) was synthesized from mannose and was shown to be the best competitive inhibitor of beta-mannosidase so far reported (Ki = 25 nM).