Putting the Risk of Breast Cancer in Perspective

Princess Margaret Hospital, Toronto, ON, Canada.
New England Journal of Medicine (Impact Factor: 55.87). 02/1999; 340(2):141-4. DOI: 10.1056/NEJM199901143400211
Source: PubMed
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    • "Every year more than 1 million women are newly diagnosed with breast cancer, and this figure will likely reach 1.5 million with the increased number of cases arising in developing countries[1]. Many of these patients will be offered adjuvant treatment based on consideration of disease responsiveness to specific therapies[2], and almost half eventually will have local or distant relapses. "

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    • "In women with a family history of BC, the magnitude of this overestimation is profound, and difficult to modify (Lerman et al., 1995; Zakowski et al., 1997). Factors reported to affect risk perception include the familial experience of cancer, myths and beliefs about cancer aetiology and prognosis, heightened media attention and an anxious preoccupied coping style, associated with intrusive thoughts about developing BC (Baker, 1991; Wellisch et al., 1991, 1992; Kash et al., 1992; Kelly, 1992; Black et al., 1995; Lerman et al., 1995; Zakowski et al., 1997; Phillips et al., 1999). "
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