Article

Edelman: Socioeconomic and Behavioural Factors Leading to Acquired Bacterial Resistance to Antibiotics in Developing Countries

Obafemi Awolowo University, Ile-Ife, Nigeria.
Emerging infectious diseases (Impact Factor: 6.75). 01/1999; 5(1):18-27. DOI: 10.3201/eid0501.990103
Source: PubMed

ABSTRACT

In developing countries, acquired bacterial resistance to antimicrobial agents is common in isolates from healthy persons and from persons with community-acquired infections. Complex socioeconomic and behavioral factors associated with antibiotic resistance, particularly regarding diarrheal and respiratory pathogens, in developing tropical countries, include misuse of antibiotics by health professionals, unskilled practitioners, and laypersons; poor drug quality; unhygienic conditions accounting for spread of resistant bacteria; and inadequate surveillance.

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Available from: Robert Edelman, Apr 21, 2014
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    • "Reported factors associated with the development of antibiotic resistance include nonadherence , under dosing, counterfeit products and irrational use of the drugs in human and veterinary medicine (Prescott & Baggot, 1993; Okeke et al., 1999; van den Bogaard & Stobberingh, 2000; Singer et al., 2003; Turnidge, 2004; Phillips et al., 2004). * Correspondence E-mail: jchilongola@kcri.ac.tz "
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    • "The high level of resistance to tetracyclines obtained in this study may be as a result of it being the most commonly available antimicrobial agent used as a growth promoter and routine chemoprophylaxis among livestock in Nigeria (Olatoye 2010). Penicillin and tetracycline are known to be extensively used in developing countries to treat respiratory infections, diarrhoea, mastitis and other infectious diseases in beef and dairy cattle (Hart and Ariuki 1998; Okeke et al. 1995). "
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    • "The development of bacterial resistance to antibiotics has become an important health problem; it is common in isolates from healthy persons and from patients with community acquired infections in developing countries. Resistance is increasing, particularly to first line, inexpensive, and broadspectrum antibiotics but also to the new drugs; therefore the search of new alternatives is necessary [1] [2]. In the specific case of dental caries there are reports of bacterial resistance to the substances used to prevent this disease [3]. "
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