Article

Laboratory measures of aggression and impulsivity in women with Borderline Personality Disorder

Department of Psychiatry and Behavioral Sciences, Harris County Psychiatric Center, University of Texas, Houston 77030, USA.
Psychiatry Research (Impact Factor: 2.47). 04/1999; 85(3):315-26. DOI: 10.1016/S0165-1781(99)00011-6
Source: PubMed

ABSTRACT

To characterize how severe negative affect in women is reflected in objective measures of aggression and impulsivity, the aggressive and impulsive behavior of 14 hospitalized women with borderline personality disorder (BPD) was compared with that of 17 controls. In an impulsivity task, subjects experienced two sets of 50 trials during which they could choose a smaller, immediate monetary reward or a larger but progressively delayed reward. In a separate task (PSAP), subjects earned monetary reinforcers with repeated button presses, and were provoked by the subtraction of money which was blamed on a fictitious other participant. Subjects could respond by ostensibly subtracting money from the fictitious subject (the aggressive response). While selection frequency of the short-delay responses was similar in patients and controls, BPD patients responded to avoid longer delay of reward across trials, and had higher Barratt Impulsiveness Scale total scores and attentional subscale scores. BPD patients responded to the money losses with roughly three times as many aggressive responses as controls and had higher Buss-Durkee Hostility Inventory (BDHI), Brown History of Violence, and Retrospective Overt Aggression Scale scores than controls. Aggressive responding rates correlated positively with BDHI scores. These results extend previous findings that negative affect in women is reflected in laboratory behavioral measures.

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Available from: James Bjork, Feb 20, 2015
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    • "More recently, researchers have taken an interest in comparing discounting behavior in groups who exhibit symptoms of a given psychiatric disorder and those who do not. These studies have found evidence for steeper discounting amongst patients with symptoms of schizophrenia (Heerey et al., 2007, 2011; Ahn et al., 2011; MacKillop and Tidey, 2011; Wing et al., 2012; Avsar et al., 2013; Weller et al., 2014), depression (Takahashi et al., 2008; Dennhardt and Murphy, 2011; Dombrovski et al., 2012; Imhoff et al., 2014; Pulcu et al., 2014), mania (Mason et al., 2012), attention deficit hyperactivity disorder (ADHD) (Barkley et al., 2001; Tripp and Alsop, 2001; Bitsakou et al., 2009; Paloyelis et al., 2010a,b; Scheres et al., 2010; Scheres and Hamaker, 2010), anxiety disorder (Rounds et al., 2007) and cluster B personality disorder (Dougherty et al., 1999; Moeller et al., 2002; Petry, 2002; Dom et al., 2006a,b; Lawrence et al., 2010; Coffey et al., 2011). This line of enquiry is not without theoretical justification, for example the broader construct of impulsivity, defined as taking action without forethought or regard for consequences (Moeller et al., 2001), of which discounting is an element, is a defining feature of some psychiatric disorders, for example borderline personality disorder (Moeller et al., 2001; DSM V, 2013) and mania (Swann, 2009). "
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    Preview · Article · Jan 2016 · Frontiers in Psychology
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    • "), and suicidal behavior (Patros et al., 2013). Impulsivity is a multidimensional construct that can be assessed by examining the speed/accuracy of responses to stimuli (i.e., motor impulsivity;Dougherty, Bjork, Huckabee, Moeller, & Swann, 1999) or the ability/inability to delay immediate gratification to obtain a more optimal outcome (Madden & Bickel, 2010;Swann, Bjork, Moeller, & Dougherty, 2002). While numerous experimental measures have been designed to assess ADHD-related motor-impulsivity (e.g., stop-signal tasks, continuous processing tasks, go/no-go tasks), the examination of impulsive decisionmaking by children with ADHD has been limited to one paradigm. "
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    • "A lack of impulse control could be a risk factor for drug addiction [2], criminal involvement [3], and suicide [4] [5]. Moreover, disrupted impulse control has been observed in psychiatric disorders such as attention-deficit/hyperactivity disorder [6] [7], antisocial or borderline personality disorders [8] [9], and bipolar disorder [10] [11]. Thus, elucidating the neural basis of impulse control would be an important contribution to modern society. "
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