Ectodermal dysplasia (ED) is a rare hereditary disease. The ectoderm-derived tissues and organs such as dental, alveolar bone, hair, nails, eyebrows and skin consist of various anomalies and developmental disorders. Patients with ED are developing functional and aesthetic problems due to structural and functional problems, broken jaws and teeth. In these patients, it is recommended to apply by ... [Show full abstract] modifying the prosthetic treatment. In our case report, were tried raising living standards providing rehabilitation ED with six cases. For the treatment of ED patients, in terms of oral and teeth health requires a multidisciplinary and professionals approach.