Testicular and epididymal changes in rams following intoxication by Ferula communis

ArticleinThe Veterinary record 150(1):24-5 · February 2002with4 Reads
DOI: 10.1136/vr.150.1.24 · Source: PubMed
  • [Show abstract] [Hide abstract] ABSTRACT: The origin of oral anticoagulant therapy and anticoagulant rodenticides traces back to investigations of moldy sweet-clover poisoning. This disease of cattle in Wisconsin is characterized by high mortality and internal bleeding. Investigations revealed that the diseased cattle are fed moldy sweet-clover hay. The phrase oral anticoagulants normally refer to these chemicals when used therapeutically. Anticoagulant rodenticides are the most common rodenticide exposure of dogs and the most common toxin seen in many US veterinary practices. Dogs suspected of anticoagulant rodenticide poisoning in the Netherlands had brodifacoum, bromadiolone, difenacoum, difethialone, and chlorophacinone. Assessment of potential toxicity of pindone for domestic animals has also been made. Warfarin and its congeners are still used as therapeutic agents. Oral anticoagulants are used for decades and a number of adverse events are recognized. The chapter also discusses the application of the chemical progeny of dicoumarol to pest control.
    Chapter · Dec 2007