Nazarov Reagents for Convergent and Expedient Synthesis of New Steroids

ArticleinOrganic Letters 4(7):1091-4 · May 2002with22 Reads
Impact Factor: 6.36 · DOI: 10.1021/ol017274r · Source: PubMed
Abstract

[reaction: see text] A new methodology for the convergent synthesis of tetracyclic compounds was developed. Two new bicyclic Nazarov reagents of type II were synthesized, and their cycloaddition with 2-carbomethoxy-2-cyclohexenone I was studied. This cycloaddition afforded new interesting steroidal backbones.