The Wright-Giemsa stain - Secrets revealed

ArticleinClinics in Laboratory Medicine 22(1):15-23 · April 2002with438 Reads
Impact Factor: 1.37 · DOI: 10.1016/S0272-2712(03)00065-9 · Source: PubMed
Abstract

The colorful story of the development of the Wright-Giemsa stain is retold. Dramas are replayed, secrets are exposed, and laurels are properly returned to scientists long forgotten. The delicately balanced chemical composition of the stain, once enigmatic, is defined. Finally, an attempt is made to unshroud some of the mystery surrounding the staining method; tried-and-true procedures and useful snippets of laboratory lore are provided. Scientific explanations and reliable methods aside, however, the stain continues to possess a certain mystique, seemingly consisting of equal parts technical expertise, art, and magic.