Article

Determination of benzene in urine by static headspace gas chromatography

Institute for Medical Research and Occupational Health, Zagreb, Croatia.
Archives of Industrial Hygiene and Toxicology (Impact Factor: 0.93). 09/2002; 53(3):197-202.
Source: PubMed

ABSTRACT

This paper describes the application of static headspace gas chromatography in determining benzene in urine. The method was analytically validated for sensitivity (DL = 42 ng/l), repeatability (RSD = 3% and 4%), and accuracy (71%), and was applied in measuring urine benzene in nonsmokers (N = 14) and smokers (N = 18). All urine samples had measurable benzene concentrations. The method proved sensitive enough to establish a significant statistical difference (P < 0.000614) in urine benzene concentrations between smokers (mean = 760; range = 181-1869 ng/l) and nonsmokers (mean = 214; range = 61-515 ng/l).

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