Systemic 5-fluorouracil producing an inflammatory response in porokeratosis

Boston University, Boston, Massachusetts, United States
Journal of the European Academy of Dermatology and Venereology (Impact Factor: 2.83). 04/2003; 17(2):190-2. DOI: 10.1046/j.1468-3083.2003.00575.x
Source: PubMed


Topical 5-fluorouracil has been used as an effective treatment for porokeratosis. Upon its treatment, an inflammatory effect occurs with the topical 5-fluorouracil. We report a case of a patient with disseminated superficial actinic porokeratosis displaying a comparable inflammatory process following therapy with systemic 5-fluorouracil used to manage a metastatic breast cancer.

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