Efficacy of knee tape in the management of knee osteoarthritis: a blinded randomised controlled trial. Br Med J

Centre for Sports Medicine Research and Education, School of Physiotherapy, University of Melbourne, Victoria, 3010, Australia.
BMJ (online) (Impact Factor: 17.45). 08/2003; 327(7407):135. DOI: 10.1136/bmj.327.7407.135
Source: PubMed


To test the hypotheses that therapeutic taping of the knee improves pain and disability in patients with osteoarthritis of the knee and that benefits remain after stopping treatment.
Randomised single blind controlled trial with three intervention arms (therapeutic tape, control tape, and no tape) of three weeks' duration and three week follow up.
Outcome assessment was performed in a university based laboratory. Taping interventions were applied by eight physiotherapists in metropolitan private practice.
87 patients with symptoms of knee osteoarthritis as defined by the American College of Rheumatology.
Primary outcome measure was pain as measured by visual analogue scale and participant perceived rating of change. Secondary measures of pain and disability included the Western Ontario and MacMaster Universities osteoarthritis index, knee pain scale, and the SF-36.
The therapeutic tape group reported a greater reduction in pain on all primary outcomes than either of the other two groups. A significant association was evident between intervention and change in pain at three weeks (P=0.000), with 73% (21/29) of the therapeutic tape group reporting improvement compared with 49% (14/29) of the control tape group and 10% (3/29) of the no tape group. Significantly greater improvement in pain and disability was observed on most secondary outcomes in the therapeutic tape group compared with the no tape group. Benefits of therapeutic tape were maintained three weeks after stopping treatment.
Therapeutic knee taping is an efficacious treatment for the management of pain and disability in patients with knee osteoarthritis.

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    • "Some studies reveal that serum prostaglandin E2 (PGE2), interleukin-1 (IL-1), and interleukin-6 (IL-6) were decreased, while í µí»½-endorphin (í µí»½- EP) was increased in OA patients after using TCHPs [14] [15]. (2) They have a slight fixation effect and could help patients overcome fear of pain as taping [4] [16]. (3) The way of dispelling " cold evil, " removing " dampness evil, " and activating blood circulation might possibility have an impact on the immune and neurochemical systems to improve TCM syndrome [4]. "
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    ABSTRACT: Objective. The aim of this study is to systematically evaluate the evidence whether traditional Chinese herbal patches (TCHPs) for osteoarthritis (OA) are effective and safe and analyze their medication patterns. Methods. A systematic literature search was performed using all the possible Medical Subject Headings (MeSH) and keywords from January 1979 to July 2013. Both randomized controlled trials (RCTs) and observational studies were included. Estimated effects were analyzed using mean difference (MD) or relative risk (RR) with 95% confidence intervals (CI) and meta-analysis. Results. 86 kinds of TCHPs were identified. RCTs and controlled clinical trials (CCTs) which were mostly of low quality favored TCHPs for local pain and dysfunction relief. TCHPs, compared with diclofenac ointment, had significant effects on global effectiveness rate (RR = 0.50; 95% CI (0.29, 0.87)). Components of formulae were mainly based on the compounds "Xiao Huo Luo Dan" (Minor collateral-freeing pill) and "Du Huo Ji Sheng Tang" (Angelicae Pubescentis and Loranthi decoction). Ten kinds of adverse events (AEs), mainly consisting of itching and/or local skin rashes, were identified after 3-4 weeks of follow-up. Conclusions. TCHPs have certain evidence in improving global effectiveness rate for OA; however, more rigorous studies are warranted to support their use.
    Full-text · Article · Jan 2014 · Evidence-based Complementary and Alternative Medicine
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    • "Pain was evaluated with more than one PRO in 35 trials [18–21, 23–42, 45–55], and disability was evaluated in 15 trials [18, 19, 21, 22, 25, 26, 29, 31, 38, 40, 43, 44, 46, 53, 54]. More than one intervention group was compared in 14 trials measuring pain [19, 24, 25, 27–29, 34–36, 41, 42, 48–50, 55] and in 4 trials measuring disability [22, 25, 29, 40]. "
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    ABSTRACT: Objectives. To develop a prioritised list based on responsiveness for extracting patient-reported outcomes (PROs) measuring pain and disability for performing meta-analyses in knee osteoarthritis (OA). Methods. A systematic search was conducted in 20 highest impact factor general and rheumatology journals chosen a priori. Eligible studies were randomised controlled trials, using two or more PROs measuring pain and/or disability. Results. A literature search identified 402 publications and 38 trials were included, resulting in 54 randomised comparisons. Thirty-five trials had sufficient data on pain and 15 trials on disability. The WOMAC "pain" and "function" subscales were the most responsive composite scores. The following list was developed. Pain: (1) WOMAC "pain" subscale, (2) pain during activity (VAS), (3) pain during walking (VAS), (4) general knee pain (VAS), (5) pain at rest (VAS), (6) other composite pain scales, and (7) other single item measures. Disability: (1) WOMAC "function" subscale, (2) SF-36 "physical function" subscale, (3) SF-36 (Physical composite score), and (4) Other composite disability scores. Conclusions. As choosing the PRO most favourable for the intervention from individual trials can lead to biased estimates, using a prioritised list as developed in this study is recommended to reduce risk of biased selection of PROs in meta-analyses.
    Full-text · Article · Jun 2012
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    • "First, herbal patches may act as the kneepad. It has been shown to have slight fixation effect and could help patients overcome fear of pain as tape [26, 27]. Second, since TCM believes that disease is linked with the aging and feebleness, long-term strain, invasion of wind, cold, or dampness evil [12], herbal patches could treat local and even systemic conditions through the way of dispelling cold evil, removing dampness evil, activating the blood, and resolving stasis [28]. "
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    ABSTRACT: Objective. To assess the short-term efficacy and safety of two kinds of Traditional Chinese herbal patches, Fufang Nanxing Zhitong Gao (FNZG) and Shangshi Jietong Gao (SJG), for painful knee osteoarthritis (OA). Methods. Patients were randomly enrolled in a double-blind, placebo-controlled study to receive FNZG (n = 60), SJG (n = 60), or placebo patch (n = 30) for 7 days. Outcome measures included visual analogue scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Traditional Chinese Medicine Syndrome Questionnaire (TCMSQ) subscale. Results. Although there was no significant difference among, three groups in short-term pain management, patients receiving FNZG got significant improvement in symptom of fear of coldness as compared with placebo patch (P = 0.029). The most common local adverse events of rash, itching, erythema, and slightly damaged skin were observed in 7% of participants. Conclusions. FNZG may be a useful treatment for symptom of knee OA and merits long-term study in broader populations.
    Full-text · Article · Feb 2012 · Evidence-based Complementary and Alternative Medicine
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