Uptake of Fluorine-18-Fluorodeoxyglucose in Pulmonary Mycobacterium avium Complex Infection

ArticleinInternal Medicine 42(8):726-9 · September 2003with4 Reads
DOI: 10.2169/internalmedicine.42.726 · Source: PubMed
Two patients showing abnormal fluorine-18-fluorodeoxyglucose (FDG) uptake due to Mycobacterium avium complex (MAC) infection are presented. Intense focal FDG uptake in the lung field could have been caused by an infectious disease such as MAC. This should be considered as a possibility when FDG whole-body scans of patients with pulmonary nodules are interpreted. To our knowledge, this is the first description of an FDG-positron emission tomography (FDG-PET) image of MAC infection of the lung.
    • "In our case of disseminated disease, CT finding of spleen was unremarkable, although FDG PET revealed a focal hypermetabolic lesion. FDG uptake increases when metabolic activity is increased by the presence of inflammatory cells, and there are several reports related to FDG accumulation in MAC infection13,14. Moreover, FDG PET can well demonstrate the activity of disseminated MAC, assess the treatment response after anti-MAC therapy, and provide suitable biopsy sites15. "
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