Project

SECRET-ITN

Goal: A MARIE SKŁODOWSKA-CURIE ACTIONS (MSCA) Innovative Training Network (ITN)

Exploring the SECRETory pathway regulation and its contribution to cancer by providing a highly qualified platform for European research training of bright young scientists, with the aim of defining secretory pathway-linked candidate biomarker genes suitable for cancer diagnosis and prognosis.

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Project log

Angelika Hausser
added a research item
As membrane-associated master regulators of cytoskeletal remodeling, Rho GTPases coordinate a wide range of biological processes such as cell adhesion, motility, and polarity. In the last years, Rho GTPases have also been recognized to control intracellular membrane sorting and trafficking steps directly; however, how Rho GTPase signaling is regulated at endomembranes is still poorly understood. In this review, we will specifically address the local Rho GTPase pools coordinating intracellular membrane trafficking with a focus on the endo- and exocytic pathways. We will further highlight the spatiotemporal molecular regulation of Rho signaling at endomembrane sites through Rho regulatory proteins, the GEFs and GAPs. Finally, we will discuss the contribution of dysregulated Rho signaling emanating from endomembranes to the development and progression of cancer.
Raluca Tamas
added an update
SECRET
European Training Network
15 New PhD Student positions
Applications are invited from candidates of excellence wishing to pursue a PhD degree in the field of cancer cell biology. Students will receive training within a pan-European academic/private sector research training network, specifically focused on breast and colorectal cancer research. Please see the project descriptions below for further information.
Submission: Applicants should submit the documentation to SECRET@izi.uni-stuttgart.de, writing on the subject line the number of their preferred projects (Example: Projects 1.8 and 2.7) by October 15, 5:00 PM (CET).
Each Early Stage Researcher (ESR) will be the driving force of an Individual Research Project (IRP), to be completed within 3 years. The ERS will be hosted in one of the beneficiaries’ labs, and will have the opportunity to complement his/her work with at least two secondments within beneficiary or partner institutions.
For more information, please check the EURAXESS job posting. https://euraxess.ec.europa.eu/jobs/437988
Eligibility
Who can apply?
Applicants shall, at the time of recruitment by the host organisation, be in the first four years (full-time equivalent research experience) of their research careers and not yet have been awarded a doctoral degree.
Full-Time Equivalent Research Experience is measured from the date when a researcher obtained the degree which would formally entitle him/her to embark on a doctorate.
Mobility Rule: at the time of recruitment by the host organisation, researchers must not have resided or carried out their main activity (work, studies, etc.) in the country of their host organisation for more than 12 months in the 3 years immediately prior to the recruitment date*. Compulsory national service and/or short stays such as holidays are not taken into account.
Secondments. The recruited researchers will be seconded to other beneficiaries and/or to partner organisations for duration of up to 30% of their recruitment period. Normal practice during secondments is for the researchers to keep their contract with the sending institution, which also pays their travel and subsistence expenses (e.g. accommodation). During their secondment, researchers receive supervision and training at the premises of the receiving beneficiary or partner organisation.
* recruitment date = the start date of the work
 
Raluca Tamas
added an update
For a teaser, in case you are looking for a PhD position in cancer research, check out our poster to discover how to apply and why our project is so attractive!!!
 
Raluca Tamas
added an update
Applications are invited from candidates of excellence wishing to pursue a PhD degree in the field of cancer cell biology. Students will receive training within a pan-European academic/private sector research training network, specifically focused on breast and colorectal cancer research. Please see the project descriptions below for further information.
Submission: Applicants should submit the documentation to SECRET@izi.uni-stuttgart.de, writing on the subject line the number of their preferred projects (Example: Projects 1 and 3) by September 30, 5:00 PM (CET).
Each Early Stage Researcher (ESR) will be the driving force of an Individual Research Project (IRP), to be completed within 3 years. The ERS will be hosted in one of the beneficiaries’ labs, and will have the opportunity to complement his/her work with at least two secondments within beneficiary or partner institutions.
For more information, please check the EURAXESS job posting 437988 (https://euraxess.ec.europa.eu/jobs/437988) or https://secret-itn.eu/jobs/
 
Raluca Tamas
added a project goal
A MARIE SKŁODOWSKA-CURIE ACTIONS (MSCA) Innovative Training Network (ITN)
Exploring the SECRETory pathway regulation and its contribution to cancer by providing a highly qualified platform for European research training of bright young scientists, with the aim of defining secretory pathway-linked candidate biomarker genes suitable for cancer diagnosis and prognosis.