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Remove heavy metals from the body naturally

Goal: Some foods/ vegetables and crops can help detoxifying and getting rid of heavy metals( Lead, Cadmium, Mercury, arsenic and Nickel ,.......from the body. These foods bind to the metals and remove them in the digestive process.

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Valentin Vasilev
added 2 research items
PRESENTATION: "UNIVERSITY TRAINING OF STUDENTS UNDER "PUBLIC ADMINISTRATION" - GOOD PRACTICES", Annual Meeting of Human Resources Specialists; 2020; INSTITUTE OF PUBLIC ADMINISTRATION'; Council of Ministers of the Republic of Bulgaria
Parisa Ziarati
added a research item
Due to the low dietary value of crops, Zn-deficient soils and insufficient intake of other minerals, soil fortification is often necessary. Fortification is defined as the addition of one or more crucial nutrients to a food to reduce poverty in a population or specific population groups. Currently available technologies for rice fortification with vitamins and minerals are high-energy and time-consuming methods. Therefore, mineral enrichment of crops has received much attention from scientists. The originality of the current study consists in determining the optimal use of hard hazelnut shells, orange peel and rice husks for enrichment of paddy soil and simultaneous immobilization of heavy metals. The combination of the identified wastes, namely hazelnut shells, orange peel and rice husks, showed good potential for immobilization/elimination or reduction of heavy metals to less than permissible limits. Therefore, the use of this combination could be an effective strategy to both introduce new micronutrients into rice grain and remove heavy metals.
Imilla I. Arias-Olguín
added an update
Cecilia Nwadiuto Amadi, Samuel Offor, Chiara Frazzoli and Orish E Orisakwe. June 2019Environmental Science and Pollution Research 26(16)
DOI: 10.1007/s11356-019-05104-2
"The global burden of heavy metal especially mercury, arsenic, lead, and cadmium toxicities remains a significant public health challenge. Developing nations are particularly at high risk and carry the highest burden of this hazard. Chelation therapy has been the mainstay for treatment of heavy metal poisoning where the chelating agent binds metal ions to form complex ring–like structures called “chelates” to enhance their elimination from the body. Metal chelators have some drawbacks such as redistribution of some heavy metals from other tissues to the brain thereby increasing its neurotoxicity, causing loss of essential metals such as copper and zinc as well as some serious adverse effects, e.g., hepatotoxicity. The use of natural antidotes, which are easily available, affordable, and with little or no side effects compared to the classic metal chelators, is the focus of this review and suggested as cheaper options for developing nations in the treatment of heavy metal poisoning."
 
Imilla I. Arias-Olguín
added an update
Chetan Rajak, Neelu Singh and Poonam Parashar. Environ Sci Pollut Res Int. 2020 Dec.
"Toxicity due to heavy metals (HM), specifically mercury (Hg), arsenic (As), lead (Pb), and cadmium (Cd) remains a challenge to scientists till date. This review gives insights into natural antidotes for the management and prevention of HM toxicity. Various databases such as PubMed, Embase, and Science Direct were searched for available facts on natural antidotes and their commercial products against HM toxicity till date. Toxicity owing to such metals needs prevention rather than therapy. Natural antidotes, fruits and vegetables, rich in antioxidant are the answers to such toxicities. Synthetic chelators impart a major drawback of removing essential metals required for normal body function, along with the toxic one. Natural antioxidants are bestowed with scavenging and chelation properties and can be alternative for synthetic chelating agents. Natural compounds are abundantly available, economic, and have minimal side effects when compared with classical chelators. Prevention is better than cure and thus adding plentiful vegetables and fruits to our diet can combat HM toxicity-related illness."
Rajak C, Singh N, Parashar P. Metal toxicity and natural antidotes: prevention is better than cure. Environ Sci Pollut Res Int. 2020 Dec;27(35):43582-43598. doi: 10.1007/s11356-020-10783-3. Epub 2020 Sep 19. PMID: 32951168.
 
Parisa Ziarati
added an update
Environmental pollution is one of the major problems of the world and it is increasing day by day due to urbanization and industrialization. Over the last few decades large scale usage of chemicals in various human activities have thrown very fast, particularly in a country like India which has to go for rapid industrialization in order to sustain over growing large problem of population. The current pattern of industrial activity alters the natural flow of materials and introduces novel chemicals into the environment. The released organic compounds and heavy metals are one of the key factors that exert negative influences on man and environment causing toxicity to plants and other forms of biotics and abiotics that are continually exposed to potentially toxic heavy metals. Of the various sources of pollutants industriel effluents containing heavy metals pose a threat to the ecosystem. These metals are present in the waste water of different industries such as metal cleaning, oil refineries, mining, electroplating, paper and pulp, paint, textile and tanneries. Water used in these industries creates a waste that has potential hazards for our environment because of the introduction of various contaminants such as heavy metals into soil and water. This article briefly describes the possible natural ways to eliminate toxic heavy metals thereby to attain good health.
Reference is attached!
 
Parisa Ziarati
added an update
Underlying individuals’ unique, invaluable, and enigmatic metaphysical qualities, the human organism is, in a physical sense, essentially a self-regulating biochemical machine. At any moment, our thoughts and feelings, our actions, metabolism and physical well-being all stem from the sum of dynamic, intricate biochemistry working within a distinctive genetic context; innumerable biochemical reactions are taking place to prepare the enzymes, hormones, neurotransmitters and all that we need to undertake the tasks required for daily life. We are truly wonderfully crafted. Like any functional system, however, in order to thrive we must receive the raw materials that we need to carry out our biological processes and we must stay away from influences that are harmful and which impair our machine from functioning normally. The widespread introduction of assorted toxic chemical agents into our intricate biochemical workings has the potential to disrupt sophisticated biochemical processes, becoming a widespread source of harm. Early life exposures can have life-long consequences, even at levels commonly experienced and thought to be safe [1, 2].
Attention to toxic chemical exposures and environmental health sciences has been expanding at an impressive rate. Extensive research by independent scientists as well as governments has prompted numerous toxicology, medical, public health and other scientific journals to report on the impacts of environmental determinants on human health. With the recognition that recent and emerging changes in the external environment have the potential to influence genetic function, hormonal biology, the gastrointestinal microbiome, and mitochondrial processes, as well as other important physiological parameters, the significance of environmental medicine on individual and population health is rapidly becoming a major area of study for scientists and public health officials.
A concern that has become increasingly manifest is that persistent toxicants are retained within the human body long after the primary exposure [3]. Many toxic compounds have long half-lives; they biomagnify up the food chain, and some are increasingly found in the air we breathe, water we drink, food we consume, and assorted personal care products we apply to our skin. Moreover, many persistent pollutants accumulate in developing children through vertical transfer from mother to child in utero and via breast milk [4]. As a consequence, many individuals now carry heavy body burdens of persistent toxicants, which often increase with advancing age as a result of ubiquitous exposures. Furthermore, despite some nations’ regulations to restrict the ongoing use of some toxicants, historical contamination of persistent pollutants and regional release in other jurisdictions lacking restrictions have resulted in ongoing exposures and bioaccumulation throughout much of the world.
While the chemical revolution was birthed and grew prolifically over the last 5 to 6 decades, it appears that we will be spending much of the next few decades trying to deal with the fallout of this revolution. Future generations may look back with astonishment and wonder how our culture thought it could stand by and tolerate the poisoning of its people and somehow not anticipate the ravages of widespread disordered biochemistry and ill health. With the mounting severity of the toxicant bioaccumulation problem, however, organizations such as the Pediatric Academic Societies have begun to speak out announcing that “low level exposure to environmental toxicity may be impacting the functioning of the current generation” [5]. Furthermore, with the recognition of the potential damage to children, the World Health Organization recently expressed the urgent need to build “Children’s Environmental Health Capacity among Health Care Professionals” [6].
 
Amina Sultan
added a research item
The definite mechanism of SARS-CoV-2 transmission remains unclear, but it is certain that basically it is through aerosols produced by coughing or other sources. Besides, these aerosolized droplets can remain suspended in an area, even after the person responsible for the transmission has left and thus may result in the surface contamination and infection of the health-care professionals. Most of the dentists worldwide are anxious and have chief concerns about aerosols. Aerosols containing the virus can be a risk. So far, no clear evidence in the literature exists that aerosols containing the virus have affected people and of course, no proof to reject that, either. Most of the dentists have profound fear and anxiety of getting infected while working during the current viral outbreak that has usually been due to the overwhelming reports on the COVID-19 pandemic. Most dental professionals get exposed to infections, and older generations have lived through various health scares in the past, including HIV and SARS. Indeed, there is so much we still don’t know about COVID-19, but we can’t live with this fear for eternity; we have to find a way to live with this pandemic. Since the aerosols increase during and after the dental procedures, therefore, the Dental offices should adhere to CDC and OSHA guidelines to reduce the risk of transmission of infections. In consideration of the current situation, it will be a wise decision to decrease patient contact, restrict the generation of aerosols and use the best PPE.
Amina Sultan
added a research item
The central giant cell granuloma (CGCG) presents as a benign, painless, slow-growing swelling of the jaw. These lesions are reported more frequently in females and most often occur in the mandible. Radiographically, it presents as a distinct delineated bony pathology with a loss of lamina dura around teeth. There can be frequent signs of displacement of teeth and tooth germs. Currently, the usually followed surgical treatment of the CGCG ranges from simple curettage to en-bloc resection. The extensive resection of aggressive and larger lesions inevitably results in the loss of teeth and tooth germs, especially in younger patients. Since, calcitonin has a direct inhibiting effect on osteoclasts and is efficient in controlling diseases with increased osteoclast activity, such as Paget's disease, and osteoclastic bone metastases, hence serve as a promising alternative. This paper presents the effectiveness and safety of Calcitonin nasal spray, in the management of a CGCG of the jaw, in an 8-year-old patient who was given calcitonin as first-line therapy.
Parisa Ziarati
added a research item
Background Lung cancer is the most frequent cancer and the leading cause of cancer all around the world. Experimental data from Zanjan hospitals revealed a significant urinary arsenic content in lung cancer patients along with some anthropogenic aspects of lifestyle. In this study, the relationship between lung cancer and arsenic as well as other risk factors will be evaluated. Methods In a descriptive-analytic and cross-sectional study performed from 10 January to 30 August 2020, 155 people, 65.2% men and 34.8 % women were selected for evaluation and the amount of arsenic in urine samples were determined with anodic stripping voltammetry method and chemtronics protocol No AN027v2. Results Urinary arsenic concentration in lung cancer patients over 40 years old was 4 times, and in patients, 20-40 years old group was 3 times more than control groups. Urinary arsenic contents in lung cancer patients in all age categories are much lower by drinking Herbal Tea (p <0.001). A strong correlation between gender (male, p <0.001) and depression (p <0.001) with lung cancer was observed. Conclusions The results of the current study reveal that arsenic is one of the main factors contributing to Lung cancer. Besides, statistical analysis showed that men are (3.5 times in a high-risk population), depression, asbestos exposure, working in mine are other significant factors which highly affected patients.
Amina Sultan
added 2 research items
The novel severe acute respiratory syndrome (SARS‑CoV‑2) originated in Wuhan, Hubei Province of China, in December 2019, and due to its rapid spread rate, the WHO declared COVID‑19 a pandemic and a public health emergency of international concern. The transmission of any infection in a dental office can occur while coming in direct contact with body fluids of an infected patient, environmental surfaces or contaminated dental instruments, or from the infectious particles that have become airborne. Even though the main source of transmission are the patients showing symptoms of COVID‑19, recently, asymptomatic patients and patients in their incubation period are reported to be also the carriers of SARS‑CoV‑2, thereby increasing the risk of spread to close contacts and health‑care workers. Because any patient could be a potential asymptomatic COVID‑19 carrier, it is advisable to perform tele‑screening of all the patients reporting to the clinic. As the transmission of 2019‑nCoV via droplets and aerosol is of grave concern, as despite all the precautions taken, it is almost impossible to reduce droplet and aerosol production to zero during dental procedures, hence it is wise that the dental health professionals should not be dependent on any single infection control strategy. Keywords: Coronavirus, COVID‑19, dental health, dental risk management, pandemic, SARS‑CoV‑2 infection control
Objectives: To evaluate the association of parents 'acceptability for SDF therapy with the location of teeth, child's behaviour, age, gender or socioeconomic status. Material and methods: As parents are the decision-makers for their child, we conducted a questionnaire-based survey on 35 parents intending to assess their acceptance for SDF therapy and factors influencing their decision. For pre-treatment aesthetic evaluation of SDF application, the parents were presented with a set of pre-and post-treatment photographs of clinical cases for their observation and comparison along with the printed structured proforma. Results: Mean parental acceptance for SDF therapy for front teeth was 2.2 (SD 1.1) and 3.1 (SD 1.2) for back teeth. Cases where the child was fully cooperative, mean ratings were slightly higher for front teeth (2.5 SD 1.6) but lesser for back teeth (2.8, SD 2.2).Results showed that parental acceptance was significantly less (p<0.05) for anterior teeth and in younger children (< 3 years). Gender of the child and socioeconomic status of parents were not associated with their acceptance rates for SDF therapy. Conclusion: Longitudinal studies with a postoperative evaluation of SDF therapy acceptance should be conducted for a better understanding of this topic.
Barbara Sawicka
added 3 research items
Notification from Notulae Botanicae Horti Agrobotanici Cluj-Napoca The journal has been assessed and received national and international recognition of its high scientific quality by The National University Research Council from Romania (CNCSIS) and is indexed in Clarivate, Master Journal List - Science Citation Index Expanded and Journal Citation Reports.
Parisa Ziarati
added an update
2007 Apr;45(4):543-50. doi: 10.1016/j.fct.2006.07.024. Epub 2006 Aug 30.
Ginkgo biloba extract protects against mercury(II)-induced oxidative tissue damage in rats
Göksel Sener 1Ozer SehirliAyfer TozanAyliz Velioğlu-OvunçNursal GedikGülden Z OmurtagAffiliations expand
  • PMID: 17267089
  • DOI: 10.1016/j.fct.2006.07.024
Abstract
Mercury(II) is a highly toxic metal which induces oxidative stress in the body. In this study we aimed to investigate the possible protective effect of Ginkgo biloba (EGb), an antioxidant agent, against experimental mercury toxicity in rat model. Following a single dose of 5mg/kg mercuric chloride (HgCl(2); Hg group) either saline or EGb (150mg/kg) was administered for 5days. After decapitation of the rats trunk blood was obtained and the tissue samples from the brain, lung, liver, and kidney were taken for the determination of malondialdehyde (MDA) and glutathione (GSH) levels, myeloperoxidase (MPO) activity and collagen contents. Formation of reactive oxygen species in the tissue samples was monitored by chemiluminescence (CL) technique. BUN, creatinin, ALT, and AST levels and tumor necrosis factor-alpha (TNF-alpha) and lactate dehydrogenase (LDH) activity were assayed in serum samples. The results revealed that HgCl(2) induced oxidative damage caused significant decrease in GSH level, significant increase in MDA level, MPO activity and collagen content of the tissues. Treatment of rats with EGb significantly increased the GSH level and decreased the MDA level, MPO activity, and collagen contents. Similarly, serum ALT, AST and BUN levels, as well as LDH and TNF-alpha, were elevated in the Hg group as compared to control group. On the other hand, EGb treatment reversed all these biochemical indices. Our results implicate that mercury-induced oxidative damage in brain, lung, liver, and kidney tissues protected by G. biloba extract, with its antioxidant effects.
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  • Medicinal plants and natural products can play a significant role in mitigation of mercury toxicity.Bhattacharya S.Interdiscip Toxicol. 2018 Dec;11(4):247-254. doi: 10.2478/intox-2018-0024. Epub 2019 Oct 18.PMID: 31762676 Free PMC article. Review.
  • Biochemical and histopathological evaluation of Al2O3 nanomaterials in kidney of Wistar rats.Patlolla AK, Kumari SA, Madhusudhanachary P, Turner T, Tchounwou PB.Curr Top Biochem Res. 2018;19:1-12.PMID: 30740003 Free PMC article.
  • Natural Phytotherapeutic Antioxidants in the Treatment of Mercury Intoxication-A Review.Unsal V.Adv Pharm Bull. 2018 Aug;8(3):365-376. doi: 10.15171/apb.2018.043. Epub 2018 Aug 29.PMID: 30276132 Free PMC article. Review.
  • Toxicodynamics of Lead, Cadmium, Mercury and Arsenic- induced kidney toxicity and treatment strategy: A mini review.Rana MN, Tangpong J, Rahman MM.Toxicol Rep. 2018 May 26;5:704-713. doi: 10.1016/j.toxrep.2018.05.012. eCollection 2018.PMID: 29992094 Free PMC article. Review.
  • Extract of Ginkgo biloba promotes neuronal regeneration in the hippocampus after exposure to acrylamide.Huang WL, Ma YX, Fan YB, Lai SM, Liu HQ, Liu J, Luo L, Li GY, Tian SM.Neural Regen Res. 2017 Aug;12(8):1287-1293. doi: 10.4103/1673-5374.213548.PMID: 28966643 Free PMC article.
 
Parisa Ziarati
added an update
Cilantro (Coriandrum sativum) is a plant native to Mediterranean region of Europe. Cilantro has been used for at least 5000 years. The cilantro seeds, also known as coriander, has been found in ancient Egyptian tomb. Coriander has been used in the treatment of male infertility. The Chinese people have used cilantro for centuries. The ancient Egyptians used coriander tea to treat clinical conditions such as urinary tract infections and headaches. Several studies have been conducted to investigate the potential of cilantro in detoxification of heavy metals. Results of two published studies suggest that this plant could help improve mercury clearance in a number of patients poisoned with heavy metals. However, these studies showed that cilantro established a weaker bond with heavy metals in comparison to allicin of garlic and silybin of milk thistle, indicating that its administration has less priority than garlic and milk thistle. The results of another study showed that cilantro prevented localized placement of lead in mice. However, these results are remarkable for bone tissue and not for soft tissues. In other hand, the relationship between dose and response has not been observed so the presented results are not very reliable.
 
Parisa Ziarati
added an update
Natural chelating compounds:
Not only animals, but also plants produce some chelating compounds. Metallothionein content of foods may affect the bioavailability and metabolism of toxic metals such as cadmium. Metallothioneins are a superfamily of cysteine-rich, low-molecular-weight metalloproteins that bind heavy metal ions. These cytosolic metallopeptides thought to be involved in metal homeostasis, metal detoxification and oxidative stress protection, can reduce the gastrointestinal absorption and renal reabsorption of toxic metals and also stimulate detoxification processes (25,26): .
1. Fibers in food products, such as cereals and fruits, can be used as a chelating therapy, along with the main treatment, in order to cut off enterohepatic recirculation.
2. There are also some other natural polymers which are reported to be the potential absorbent of heavy metals, like algal polysaccharides alginate, chlorella and citrus pectin.
3. Since toxic metals have a high tendency to bind to sulfur containing peptides, a diet rich in foods containing sulfur such as alliums (A family of plants that include garlic and onion) and brassicas (like broccoli) are used to improve symptoms of poisoning and increase the removal of heavy metals from the body. 4. Cilantro (Coriandrum sativum) is a popular culinary and medicinal herb.
I highly recommend the paper : Heavy metals detoxification: A review of herbal compounds for chelation therapy in heavy metals toxicity Reza Mehrandish , Aliasghar Rahimian , Alireza Shahriary
J Herbmed Pharmacol. 2019; 8(2): 69-77
doi: 10.15171/jhp.2019.12
 
Parisa Ziarati
added an update
by Anthony William
Do you suffer from chronic health problems and have yet to find the answers you seek? If you feel that you have been searching for answers for far too long, you are not alone. You may already be doing everything you can think of to keep yourself healthy. You stick to your organic diet. You get as much exercise as you can tolerate. You meditate. You take your daily supplements. You take time for yourself. As far as you can tell, you’re doing everything right, and yet, your symptoms persist. Fatigue. Migraine headaches. Joint pain. Brain fog. Sluggishness. Inflammation. Constipation and other digestive disturbances. Susceptibility to infections. Nervousness and anxiety. Insomnia. Poor memory. Yeast and bacterial overgrowth. Skin eruptions. Attentional deficits. Mood dysregulation. Sadly, these types of symptoms are becoming more and more commonplace. If you suffer from any one of these on a regular basis, odds are you have been to countless health professionals, scoured the internet, and read everything you can get your hands on, awaiting relief that never comes, or lasts only a short while. You may even have been told that it’s “all in your head,” that it’s “hormonal,” or “it’s just stress.” Yet as your symptoms continue, you keep asking yourself “What have I missed? Why does my body still feel this way?”
In this modern era, we are bombarded by toxins of every kind imaginable. Our bodies are subjected to an onslaught of dangerous chemicals on a daily basis from things like air pollution, plastics, and industrial cleaning agents, not to mention the thousands of new chemicals introduced into our environment every year. Toxins also saturate our water reservoirs, fall down from the sky, and hide out in our homes and workplaces. This has become an unfortunate reality of modern life. However, if you are experiencing any of the above symptoms, there’s a good chance that a particular class of toxins are to blame. They are known as toxic heavy metals. Heavy metal toxicity—from metals such as mercury, aluminum, copper, cadmium, nickel, arsenic, and lead—represents one of the greatest threats to our health and well-being. While heavy metal toxicity is quite common, it is not commonly diagnosed. This is because heavy metal toxicity is an elusive adversary. It stays well-hidden within our bodies, never revealing itself unless you are actively looking for it.
 
Parisa Ziarati
added an update
The body does appear to sweat out toxic materials — heavy metals and bisphenol A (BPA), a chemical found in plastics, for instance, have been detected in sweat. But there’s no evidence that sweating out such toxins improves health.
“The claims for the benefits of saunas and other sweat-inducing treatments are not backed by science,” said Dr. Harriet Hall, a retired family physician and former Air Force flight surgeon, who edits the website Science-Based Medicine and is a co-author of “Consumer Health: A Guide to Intelligent Decisions.”
The concentration of metals detected in sweat are extremely low. Sweat is 99 percent water. The liver and kidneys remove far more toxins than sweat glands.
People who have dangerously high levels of heavy metals in their body will need prescription medication, not sweating, to get rid of them, .......
 
Barbara Sawicka
added an update
The main ingredient of potatoes is starch. Starch varieties contain from 17.0 to 27% of this ingredient. The non-starch dry matter also includes: nitrogen compounds, mainly as total protein (approx. 2%), minerals (approx. 1%), organic acids (0.5%), sum of sugars (approx. 1%), sugars reducing (approx. 0.5%), lipids (0.1%) and non-starch polysaccharides, such as: cellulose, pectins, hemicellulose and lignin (1.5-2%). Potato tubers also contain at least 2 toxic compounds belonging to glycoalkaloids: solanine and chaconin in the amount of up to 10 mg per 100 g of fresh tuber weight, 90% of which is in the peel. Potatoes contain the lowest nitrates among all vegetables - up to 20 mg in 100 g of fresh tuber weight. Unlike other potato species, it does not accumulate anti-nutritional ingredients from the environment. Contains only traces of mercury, cadmium and lead, which are> 90% in and directly below the skin. As a result, most of the glycoalkaloids and heavy metals contained in tubers are removed during potato peeling. The dry matter content influences the consistency of fried, dried, sterilized, frozen and cooked products and the absorption of fat by French fries and crisps, as well as the firmness and moisture of the flesh of the cooked tubers.
 
Parisa Ziarati
added an update
Garlic and Ginger are two ancient herbs incredibly famous for its flavor and aroma when cooked with different dishes.
Garlic helps in cleaning intestinal parasites and harmful bacterias from the body while Ginger helps in the detoxification process via perspiration. Both help in aiding digestive relative problems and getting rid of harmful substances or toxins present inside the body.
Treat yourself with Ginger tea every morning that effectively soothe the body and mind and add garlic to your foods for a toxin-free diet.
 
Parisa Ziarati
added an update
With the continued emergence of data supporting the role of toxins in chronic disease processes, it is becoming increasingly necessary for clinicians to understand how to provide therapeutic modalities to reduce toxin load in patients. In this paper, several studies regarding the influence of foods and food-based nutrients on the systems of detoxification were presented. From the current information presented, listed below are some key concepts for translation into the clinical setting.
. Nonclinical versus Clinical Studies
One of the limitations that comes to the forefront in this collection of studies is how the information, in many cases, is constrained primarily to studies in cells or animals. It remains questionable as to whether similar effects would be seen in humans at moderate, reasonable doses. In the cell studies, it is difficult to anticipate findings due to the lack of pleiotropic activity that occurs in a complex, living system with multiple detoxification systems working simultaneously. Along similar lines, animal studies are often difficult to extrapolate to individuals due to the degree of variability in genotype and environmental phenotype seen in the diverse human population. Therefore, at this time, it is best to take precaution in firmly advocating foods or food-based nutrients that only have cell or animal data as support. It is best to rely on the clinical studies that have been published to date in making more firm recommendations.
. Single Agent versus Lifestyle
While this paper focuses on isolated nutrients and foods that contain those nutrients, it might be optimal from a clinical perspective to consider how an entire lifestyle might induce or inhibit the array of detoxification enzymes. For example, this paper has not addressed behaviors like smoking, physical activity, or stress. The modern clinician needs to weigh all these variables against each other. Yet, science has not fully demonstrated the individual impacts of these factors, along with all of them together. Therefore, at this time, a dietary pattern favoring whole, unprocessed, plant-based foods and the removal or reduction of toxic substances in one's environment is a two-prong approach that would seem to have the best overarching scientific underpinning.
Modulating versus Inhibiting/Inducing Effects
In several instances, certain foods exhibited a particular activity on an enzyme, while, at higher doses, they had another, opposite effect. Essentially, many foods serve as what is commonly referred to as being “bifunctional modulators,” possessing the ability to effectively induce or inhibit detoxification enzyme activity based on the dose response. Therefore, the resulting clinical takeaway might be to encourage patients to follow a mixed, varied diet, full of different plant-based, whole foods. Smaller amounts of many compounds might be more therapeutic and supportive for biochemical pathways rather than overriding signals derived from high concentrations of nutrients through high-dose supplementation or the repeat, daily ingestion of large quantities of the same food.
. Polypharmacy
For patients who are taking multiple pharmaceuticals, it is important to know which detoxification systems will be influenced by nutrients and foods so that side effects are minimized or avoided.
5.5. Dietary Supplements versus Foods
Since there can be potent effects of food-based nutrients on detoxification pathways, it would be best for the average patient to follow, as indicated above, a mixed, complex, and whole-foods diet. Additionally, dietary supplements may be a helpful adjunct in patients in which the practitioner has information about the patient's genetic variability, so that nutrients can be tailored accordingly. Without a full understanding of a patient's SNPs (single nucleotide polymorphisms), it becomes difficult to make accurate assessments about nutrients and dosing.
. Duration of Dosing
Another factor to consider in therapeutic intervention is the timing and duration of the dose of nutrient or the food. In some of the research presented here, effects on detoxification enzymes were seen after several days of food intake or supplementation, while, in other cases, induction of an enzyme might be fairly rapid, followed by efficient adaptability. This variable needs to be considered in further clinical research and requires close monitoring in clinical practice.
. Foods Known to Impact Detoxification
Based on the four systems examined in this paper, there are several foods which seem to have demonstrated an influence on detoxification systems. Many of them have been acknowledged as part of naturopathic medicine. Hence, it would be useful to have a knowledge base of this cumulative set of foods as patients embark upon detoxification protocols. This recent scientific update notes clinical evidence of effects from cruciferous vegetables (in combination, and specifically watercress, garden cress, and broccoli), allium vegetables, apiaceous vegetables, grapefruit, resveratrol, fish oil, quercetin, daidzein, and lycopene. Many other foods, beverages, and nutrient bioactive compounds, based on this review of scientific literature, are also suggested as modulators of detoxification enzymes in vivo.....
Reference:
Review Article Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application
Hindawi Publishing Corporation Journal of Nutrition and Metabolism Volume 2015, Article ID 760689, 23 pages http://dx.doi.org/10.1155/2015/760689
 
Parisa Ziarati
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Give yourself a serious antioxidant boost! Pomegranates are loaded with anthocyanins, a type of antioxidant that gives the seeds their deep, red color.
It’s possible that anthocyanins may protect against DNA damage and inflammation and reduce the risk of heart disease, allergies, cancer, and diabetes.
Preliminary research indicates that they may also help to slow skin aging by reducing the weakening of skin’s collagen and elastin fibers and preventing dark spots.
Healthy Ways to Enjoy It
The jewel-toned, sweet-tart seeds can be added to a salad or sprinkled on top of breakfast cereal. You can also have them as a snack. If you can’t get a hold of the seeds, try adding a splash of unsweetened pomegranate juice to water to liven up the taste and help you increase your fluid intake. Just be sure not to overdo it — large amounts of pomegranate juice have the potential to interact with many medications.
 
Parisa Ziarati
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A person’s toxic body burden is a result of three main factors. First, there is the toxicant exposure we each may have received from both internal and external sources, as previously discussed. Second, each person’s genetic predisposition to effectively produce detoxification enzymes for processing these compounds or substrates is unique and depends on familial influence. Last, the integration of proper nutrition and ongoing dietary ingestion of helpful detoxification nutrients or phytonutrients can impact the body’s capacity to appropriately reduce the presence of toxicants and lower the body burden. Toxic symptoms may occur when we get to our personal limit of accumulated toxins and are not able to clear them fast or efficiently enough. Medical researchers are recognizing more symptoms related to the buildup of toxins, including obesity, type 2 diabetes, metabolic syndrome, cancer, fatigue, infertility, allergies, behavior and mood disorders, and neurological conditions such as tremors, headaches, and cognitive difficulties, along with several other diseases like Parkinson’s and Alzheimer’s. The process of detoxification involves many steps. There may be reasons why the body isn’t particularly efficient about clearing toxins. These reasons can be situational, such as having an increased exposure to toxins, being constipated and thus not able to excrete toxins in the stool, being deficient in specific nutrients, eating a nutrient-poor diet, being under stress, having a chronic disease, experiencing excessive inflammation, and not getting enough physical activity or restorative sleep. There may also be genetic reasons, such as having particularly slow enzymes that aren’t efficient in converting toxins into compounds that can be excreted. The goal of a clinically-directed metabolic detoxification protocol is to provide nutritional support for facilitating the pathways involved in the processing and excretion of toxins. A detox program results in improved symptoms and an increased sense of wellbeing for most individuals. Specifically, many who participate in a personalized detoxification program describe improvement in pain and fatigue levels, enhanced cognitive function and moods, more effective and satisfying sleep cycles, and weight loss. The Detox Food Plan Comprehensive Guide provides specific food and nutrition suggestions to optimize the metabolic detoxification experience and lower the body burden. The guide offers directions in how to sequence a healthy detox and wellness plan by providing tips on how to get started, what to eat, what to watch for, and how to provide the body with the right nutrients for longstanding, improved elimination and detoxification.
A person’s toxic body burden is a result of three main factors. First, there is the toxicant exposure we each may have received from both internal and external sources, as previously discussed. Second, each person’s genetic predisposition to effectively produce detoxification enzymes for processing these compounds or substrates is unique and depends on familial influence. Last, the integration of proper nutrition and ongoing dietary ingestion of helpful detoxification nutrients or phytonutrients can impact the body’s capacity to appropriately reduce the presence of toxicants and lower the body burden. Toxic symptoms may occur when we get to our personal limit of accumulated toxins and are not able to clear them fast or efficiently enough. Medical researchers are recognizing more symptoms related to the buildup of toxins, including obesity, type 2 diabetes, metabolic syndrome, cancer, fatigue, infertility, allergies, behavior and mood disorders, and neurological conditions such as tremors, headaches, and cognitive difficulties, along with several other diseases like Parkinson’s and Alzheimer’s. The process of detoxification involves many steps. There may be reasons why the body isn’t particularly efficient about clearing toxins. These reasons can be situational, such as having an increased exposure to toxins, being constipated and thus not able to excrete toxins in the stool, being deficient in specific nutrients, eating a nutrient-poor diet, being under stress, having a chronic disease, experiencing excessive inflammation, and not getting enough physical activity or restorative sleep. There may also be genetic reasons, such as having particularly slow enzymes that aren’t efficient in converting toxins into compounds that can be excreted. The goal of a clinically-directed metabolic detoxification protocol is to provide nutritional support for facilitating the pathways involved in the processing and excretion of toxins. A detox program results in improved symptoms and an increased sense of wellbeing for most individuals. Specifically, many who participate in a personalized detoxification program describe improvement in pain and fatigue levels, enhanced cognitive function and moods, more effective and satisfying sleep cycles, and weight loss. The Detox Food Plan Comprehensive Guide provides specific food and nutrition suggestions to optimize the metabolic detoxification experience and lower the body burden. The guide offers directions in how to sequence a healthy detox and wellness plan by providing tips on how to get started, what to eat, what to watch for, and how to provide the body with the right nutrients for longstanding, improved elimination and detoxification.
 
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How heavy metals accumulate in the body
While our bodies are designed to filter and eliminate heavy metals (and other toxins), when the exposure of metals exceeds the body’s ability to detox the metals, it can create multiple problems within the body.2  Accumulation of heavy metals is usually caused by a number of factors, but some of the most common ones include exposure via:
  • Food
  • Water
  • Polluted air
  • Lead-based paint
  • Cookware
  • Factories or industrial businesses
It’s important to point out that heavy metal poisoning isn’t limited to just adults. Children are exposed to many of the same things adults are, and a growing number of children are being treated for heavy metal poisoning. With children, diagnosis can be tricky as symptoms can present themselves differently than they do with adults. Some of the most common symptoms of heavy metal poisoning include:
  • Fatigue
  • Digestive issues
Headaches
  • Achiness
Chelation
One of the most commonly used treatments for heavy metal poisoning is chelation. Chelation (pronounced “KEY-lay-shun”) refers to using a medicine or supplement to remove the toxins from the body. The medication binds to the metals in your body and then both are eliminated through the urine.3 There are also several foods—such as cilantro, garlic, chlorella, and several more—that are believed to have binding properties that can support eliminating heavy metals as well. Although chelation therapy is considered an effective treatment, it should only be administered by a qualified and knowledgeable healthcare provider and never attempted on your own.
an essential oils detox heavy metals?
Currently, there is no solid scientific evidence that suggests essential oils can remove heavy metals from the body. They do not act as binders or chelation agents. However, that is not to say that essential oils aren’t incredibly beneficial during the detoxification process. In fact, there are many essential oils that are considered detoxifiers and that would be extremely useful when detoxing heavy metals. Specifically, essential oils that support the different detoxifying organs and systems of the body can be especially beneficial when detoxing heavy metals and can aid the process tremendously.
Essential oils for detoxing heavy metals
As plant extracts, essential oils are naturally beneficial for the body. Most oils can help in a number of ways and have a direct effect on multiple systems of the body. For a thorough heavy metal detox, it’s important to ensure that the body is functioning properly. This is why it’s crucial that all the different bodily systems are working the way they’re supposed to.
While there are many essential oils that can be beneficial in supporting heavy metal detoxification, below I have included what I believe to be 6 of the best essential oils for detoxing heavy metals. Many of the oils listed below have the potential to aid the detoxification process in multiple ways by supporting multiple systems in the body.
1. Rosemary
2. Grapefruit
3. Juniper Berry
4.Cypress
5. Fennel
6. Lemon
Blend #1
  • 5 drops lemon essential oil
  • 3 drops rosemary essential oil
  • 2 drops cypress essential oil
Blend #1
  • 5 drops lemon essential oil
  • 3 drops rosemary essential oil
  • 2 drops cypress essential oil
 
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Hibiscus sabdariffa L. (roselle) belonging to the Malvaceae family is widely grown in many countries. This plant is often used in the traditional medicine being rich in phytochemicals like polyphenols especially anthocyanins, polysaccharides and organic acids thus having enormous prospective in modern therapeutic uses.
The study aimed to review and document all the available evidence and information about the calyces of Hibiscus sabdariffa (roselle) with the special focus on their nutritional composition, bioactive constituents and therapeutic uses. The electronic database was searched up to 2017, using keywords Hibiscus sabdariffa, chemical constituents of roselle, therapeutic uses of roselle. Journals, books and conference proceedings were also searched.
The review provides valuable information about the nutraceutical component of Hibiscus sabdariffa L. and their utilization for curing various degenerative diseases like hypertension, hyperlipidemia, cancer and other inflammatory diseases of liver and kidney. Their toxicological effects have also been discussed from a safety point of view.
Most studies supported and provided the scientific basis for the statement that Hibiscus sabdariffa and their active constituents play an important role in the prevention of chronic and degenerative diseases that are associated with oxidative stress. Our study suggests, that good research is needed, to establish a potential strategy that can balance the pharmacological and toxic effects of roselle and standardized fingerprint of Hibiscus sabdariffa is required internationally for quality control.
A review on phytochemistry and therapeutic uses of Hibiscus sabdariffa L.
Biomedicine & Pharmacotherapy
Volume 102, June 2018, Pages 575-586
 
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According to the recent surveys, the air and soil pollution levels have risen from the toxic metals due to accumulation of these metals in soil and plants. These concerns have become one of the basic problems of agricultural products, which lead to food contamination. In recent years, the use of low-cost bio-adsorption has been considered which is mainly due to agricultural waste. It is worth mentioning that coffee consumption is over eleven billion tons per year around the world. Coffee bean waste (canephorat, Arabica) is solid and insoluble in water, which is why it is racked up and compiled in nature. Packed potting soil purchased from Tehran market. Meanwhile in 45 vases the Coffee waste (from 0% to 5%) dry weight percentage were mixed by soil, due to observing the effect of Coffee waste as adsorbent and in defined times: 1, 10, 20, 30, 40 days in the study. ICP-MS. Ion concentration was addressed in three replicates determined the Nickel (Ni) contents in aerial parts of vegetable in treated and untreated samples. The soil, leaves of vegetable was digested by wet method according the standard protocol (AOAC). Mean values were calculated using Analysis of Variance, (ANOVA) and adsorption capacity varied by considering the effects of assorted parameters like contact time, initial concentrations, and adsorbent dose. It was acknowledged by the results that coffee bean waste (CBW) has more potential to adsorb Ni during the first days of the study (p < 0.001) and adsorption capacity was diversified by considering the effects of various parameters like contact time, initial concentrations, pH, and absorbent dose. Coffee bean waste could acquire high level of Nickel in a short time and the uptake rate by edible vegetable plant is significantly afflicted by their concentrations in the contaminated soil (p< 0.05). A contact time of 30 days by %3 corianders was resulted to be optimum.
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Green algae and some other aquatic plants are capable of absorbing mercury in the environment. It is reported that Chlorella in diet increases the clearance of mercury from the digestive tract, muscle, ligaments, connective tissue and bones (37). Chlorella is a green algae which due to its high chlorophyll content acts as a natural chelator of heavy metals, especially lead and mercury. Chlorella and cilantro as food materials can detoxify some neurotoxins such as heavy metals (example: mercury) and toxic chemicals (like: phthalates, plasticizers and insecticides) .
Ref: doi: 10.15171/jhp.2019.12
 
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Phytochelatins
Phytochelatins are oligomers of glutathione, produced by the enzyme phytochelatin synthase. They are found in plants, fungi, nematodes and all groups of algae. Phytochelatins act as chelators, and are important for heavy metal detoxification. Phytochelatins composed of three amino acids: glutathione, cysteine, glycine (Glu, Cys, Gly), have been identified in many plant species and in some microorganisms. These compounds are reported to be involved in detoxification of cadmium. Nonetheless, there is little evidence indicating the efficacy of phytochelatins on detoxification of wide range of heavy metals (34). In this regard, studies have shown that phytochelatins can form complexes with lead, mercury and silver. The biochemical mechanism underlying detoxification of heavy metals by phytochelatins is very complicated. Briefly, increased concentration of metal ions triggers the activation of the enzyme phytochelatin synthase, then metal ions form complexes with phytochelatins followed by transfer into the vacuoles to form more complexes with sulfide groups and organic acids (35).
Ref : doi: 10.15171/jhp.2019.12
 
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Key herbs which can act in this way including Allium sativum (garlic), Silybum marianum (milk thistle), Coriandrum sativum (cilantro), Ginkgo biloba (gingko), Curcuma longa (turmeric), Phytochelatins, triphala, herbal fibers and Chlorophyta (green algae) are briefly discussed below: Allium sativum Allium sativum is an herbal medication containing allin, as its main amino acid. Allin contains sulfur substitutes and in the presence of alliinase is converted to allicin, which then produces other compounds such as: vinyldithiines, ajaenes, and poly sulfides (27). Sulfur components are responsible for the smell created by garlic. Allium vegetables, such as garlic, onion, leek and chive, contain organosulfur compounds contributing to clearance of heavy metals such as lead and arsenic by the liver. Also, cruciferous vegetables, such as broccoli, cauliflower, cabbage, kale, Brussels sprouts, turnips, and kohlrabi are rich sources of sulfur-containing substances.
Ref: doi: 10.15171/jhp.2019.12
 
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COVID-19 Heavy Metal Hypothesis
A characterizing feature of coronavirus disease 2019  (COVID-19)  is that the majority of people infected fight it off effectively with few or no symptoms presented. The typical immune response is more than sufficient to overcome the virus. There is however a small section of the population that is not able to do that and tragically succumb. There is something different about this subset of the population. We know conditions that increase your risk for succumbing to the virus are age, hypertension, obesity, and diabetes. Interestingly all of these conditions are also associated with the bioaccumulation of heavy metals. Seniors have significantly higher heavy metal levels in their blood than young people because each year you typically retain more than you excrete. Heavy metals increase risk for hypertension. Mercury causes hypertension by inactivating catecholaminei-0-methyl transferase, which increases serum and urinary epinephrine, norepinephrine, and dopamine. This effect increases blood pressure.8  This relationship is so well understood that Houston (2011) states “Mercury toxicity should be evaluated in any patient with hypertension.” Heavy metals have a demonstrated  association with diabetes and obesity as well.In addition, COVID-19 deaths appear to be related to the immune system launching a “cytokine storm” excessive levels of cytokines are released triggering a chain of events that can kill the patient.18 Mercury alters the cytokine response by increasing proinflammatory cytokines. Intriguingly, the relationship is even more specific than that,  interleukin-1β (IL-1β) cytokines are at the heart of COVID-19 induced cytokine storms, these are the exact cytokines that mercury increases.19– Endemen et al (2020) found that COVID-19 is linked to hypercoagulability. This conclusion is supported by cohort studies that found hypercoagulability and a severe inflammatory state in COVID-19 patients.23,24 Hypercoagulability is one of the known effects of mercury. Viral infections activate the blood coagulation system.28 Coagulation stimulates the cytokine response and the expression of  IL-1β  genes. My hypothesis is that bioaccumulation of  heavy metals is making certain individuals more susceptible to succumbing to COVID-19. A hypothetical mechanism is illustrated in Figure 1. Mercury induced hypercoagulation is touched off by COVID-19 infection. Coagulation induces proinflammatory cytokine response exacerbated by mercury causing a cytokine storm. 
 
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Although many countries have initiated programmes to lower the level of lead in the environment, human exposure to lead remains of concern to health care providers and public health officials worldwide. For over 35 years the World Health Organization and the International Programme on Chemical Safety have been concerned about the adverse effects on health of lead in the environment. The evaluation of human health risks arising from foodborne lead has been carried out by the World Health Organization on four occasions since 1972. In addition, health-based guidance values for lead in water, air and the workplace have been developed by various task groups convened by the World Health Organization. Environmental Health Criteria 3: Lead, published in 1977, examined the effects of lead on human health, and Environmental Health Criteria 85: Lead – Environmental Aspects was published in 1989. During the past 10 years, a large body of knowledge on the effects of lead on neurobehavioural development of children at low levels of exposure has accumulated. This booklet focuses on what is known about childhood lead poisoning, an entirely preventable disease.
 
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Travis J Riddell a, Orville Solon b, Stella A Quimbo b, Cheryl May C Tan c, Elizabeth Butrick a, John W Peabody a
Introduction
Lead poisoning is one of the most significant environmental health threats children face. Even low levels of lead exposure are associated with impairment of childhood cognitive function1 and abnormal infant behaviour.2
Over the past 30 years regulatory and environmental reforms in the developed world have significantly ameliorated lead pollution among children. In developing countries, the extent of environmental lead, and ways to reduce and prevent exposures are only beginning to be understood.3 These nations have many competing health challenges and lead poisoning may be considered less important when there is uncertainty about population prevalence rates and the various correlates and sources of lead poisoning. Regulations designed to limit lead pollution are less common and less likely to be enforced compared with developed countries.4
The few investigations carried out in developing countries have studied urban populations. These indicate that the problem may be greater than realized. One cohort study of children in Mumbai and Delhi, India, reported a correlation between blood lead levels (BLL) and age, standard of living, height/weight percentile and parity.5 Around the Philippines capital Metro Manila, several small investigations found children’s elevated BLL associated with proximity to lead acid battery recycling or repair activities,6 consumption of certain foods7 and playground soil.8 In Karachi, children’s BLL were linked to proximity to the city centre, application of surma (a traditional eye make-up), parental illiteracy, paternal lead exposure at the workplace and hand-to-mouth activity.9
The Quality Improvement Demonstration Study (QIDS) is a large population-based study focused on health policy reforms’ impact on the health status and health-care utilization of children under five living in the Visayas. The baseline QIDS survey collected biomarkers, including blood lead, along with demographic, socioeconomic and child health data points. Data were collected from over 2800 children allowing for assessment of BLL in this population and analysis of the correlates.
This paper describes the prevalence of lead poisoning among these children living in a rural area that covers about one third of the Philippines. We explore the correlations of lead toxicity in this population and describe an environmental investigation to characterize an unexpectedly common toxic health hazard.
Methods
This study was approved by the ethics committees at the University of California, San Francisco, and the University of the Philippines, Diliman. The children’s parents or guardians provided written informed consent before enrolment. The sections below detail the methodological approach taken in our investigation’s three phases: description of the prevalence of lead poisoning in this population, analysis of the correlates of BLL and environmental exposure assessment to identify the potential sources of lead.
Study subjects
Children aged between six months and five years were eligible for inclusion in QIDS. A stratified random sample was used: approximately 100 children from each of the 30 identified health districts were interviewed. Half were selected randomly from households using the current National Statistics Office census frame; the other half had been discharged from hospital within the past four to eight weeks. All answered the same questionnaire. Both separate and combined models were run. The discharged patients had an average of 8% lower levels of lead. For the analysis, we use the combined sample controlling for this covariate in the models reported in the results section. Hospital-based children were tested for lead on the day of discharge; the randomly selected children were tested during a home visit.
 
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More than 800m children suffer from lead poisoning worldwide, major report reveals
One third of the world’s children suffer from lead poisoning, a new report has found, with the vast majority living in developing countries where the issue has been widely ignored. 
According to research by Unicef and Pure Earth, more than 800 million children around the world have elevated levels of lead in their blood, impairing their cognitive development. The impact of this costs countries a staggering $977 billion a year.
The scale of the problem is “far greater than previously understood”, said Nicholas Rees, one of the report’s authors.
Lead has been known as a toxic substance for centuries, he explained, but while rich countries have taken steps to dramatically reduce lead exposure – by banning lead paint for example – in low and middle income countries the issue has been widely ignored.
Today, more than 90 percent of the disease burden from lead exposure occurs in these countries, the report finds.
The last few decades have seen an increase in average blood lead levels in poor countries, particularly in Africa and Asia but also in Central and South America and Eastern Europe.
In some countries in Africa, such as Liberia, three quarters of children have blood lead levels of 5 micrograms per decilitre (g/dL), the cut-off point for intervention set by the World Health Organization (WHO).
Lead seriously damages children’s brains. Studies cited in the report show that a blood lead level of 5g/dL can lower a child’s IQ by up to five points. While previously there was thought to be a safe level, experts now recognise even smaller amounts are harmful, according to Unicef.
Young children are particularly vulnerable, absorbing four to five times more of the lead that enters their bodies than adults do. Because their blood brain barriers are not fully developed, lead passes more quickly from the blood into the brain and nervous system, said Mr Rees.
IQ loss is not the only impact. High lead blood levels are also linked to shortened attention spans and violent behaviour. Pregnant women afflicted by lead poisoning are more likely to give birth prematurely and to children with deformities. 
Although acute lead exposure can produce “an immediate and extreme impact, such as convulsions”, most of the symptoms of lead poisoning are not visible and “only become apparent over time”, said Mr Rees.
The effects of lead exposure go beyond limiting the potential of individual children, he emphasised. They also cripple the whole country’s’ economic growth through lost productivity.
Studies show that increased blood lead levels are associated with higher crimes rates, too, adding a social burden as well as another economic cost.
Today, in rich countries the sources of contamination are limited. It is also mainly poor communities who are exposed – through cheap lead paint, or water flowing from old lead pipes.
But in low and middle income countries, toxic lead is everywhere. With its insidious symptoms, however, most people remain oblivious to the risks surrounding them. As well as in paint and pipes, in places like Bangladesh, Georgia and India it is used to bulk up spices like turmeric.
Elsewhere, such as in Mexico, lead-based glazes are used on ceramic dishes used for cooking and serving food.
The biggest source of lead contamination by far, however, is used lead-acid batteries. “About 85 per cent of all lead used in the world today” goes to making these, said Mr Rees.
“The number of vehicles in low-income countries has essentially tripled since the start of the century,” he explained, especially in rapidly industrialising countries.
In Bangladesh, for example, there were 60 million vehicles in 2014, says Maya Vandement, Unicef’s Chief of Health in the country. Just five years later, this had ballooned to 504 million.
Lead-acid batteries are also used for electric vehicles. Hailed for being environmentally friendly, their growing use has a hidden trade-off.
Cars stuck in traffic in Dhaka, the capital of Bangladesh CREDIT: EPA/ABIR ABDULLAH
For example, the batteries for electric rickshaws, which are typically charged twice a day, have a short life span, explained Ms Vandement. “Then they need to be recycled – that’s where the problem is.”
Official recycling operations are subject to regulations in most countries, but the rules are scantily enforced in many parts of the developing world, according to Unicef.
An even bigger problem comes from informal recycling sites. Spewing toxic fumes into the air and contaminating land, these have boomed in the last few years.
The men (and the few women) who toil in such sites carry the contaminated dust home, exposing their children to lead poisoning. Among the poorest, the dangerous work is a lifeline, however.
In Raksa, an island in the north of Bangladesh, the whole village depends on illegal sweltering, said Dr. Lutful Kabir, a research investigator at Pure Earth. Lead recycled there gets sent to factories to be re-used, fuelling an entire underground industry.
Having grown up in Kathgora, a village next to a lead factory, when eight-year-old Anik’s blood was tested for lead the results showed a shocking 26g/dL.
“He gets angry very easily, can’t seem to focus on his studies, and isn’t growing as a kid should” said his mother, Sharmin Akter. “People in the village are beginning to realise [lead’s] harmful impacts, and they will not let it happen again.”
But combatting lead poisoning is no easy task. “As quick as we shut down illegal sweltering sites and start decontaminating the area, new ones spring up again somewhere else,” said Dr Lutful.
He and his team also focus on educating people about the risks of lead exposure and the myriad sources of contamination as well as advocating for changes to government policy. 
Creating awareness is the biggest challenge, said Mr Rees. Most communities in countries with the highest rates of lead poisoning have “no idea”. Many policy makers are little better informed, added Ms Vandement, “that needs to change”.
 
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Cellular model for antiviral testing DESCRIPTION OF THE INVENTION The invention “cellular model for antiviral testing” is based on the use of a new form of virus detection analysis, termed herein “Gold Test” (sometimes referred to herein as “GT”).
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Products that are able to remove heavy metals from the body
Coriander - is able to release mercury, cadmium, lead and aluminum from both the bone and the central nervous system. Coriander, however, can release more toxins than it can remove from the body, which is why there is a high risk of mercury redistribution and deposition in the connective tissue (where the nerves are located). This process is called retoxification. This can easily be avoided by simultaneously administering a toxin-absorbing agent in the intestine, e.g. activated carbon, diatomaceous earth or chlorella. One tablespoon of coriander per day consumed for three weeks is enough to get rid of most heavy metal deposits from the body and allow the drug to work effectively. The cleansing effect of coriander is not limited only to the digestive system, but covers the whole body, including the lungs, kidneys, endocrine glands, liver and heart.
- Chlorella - binds toxins, all known toxic metals and environmental toxins, repairs and activates the body's detoxification functions, and also significantly increases the amount of intracellular reduced glutathione. Some people do not tolerate chlorella and are allergic to it. They may have symptoms such as breathing difficulties, chest pains and hives. In this case, stop taking the supplement.
- Garlic - protects white and red blood cells against oxidative damage caused by metals in the flower during their removal from the body, and also has detoxifying functions. Garlic is also a very strong, natural antibacterial agent. Bioactive selenium contained in garlic protects the body against mercury toxicity. Unfortunately, garlic is not a sufficient chelator.
- Selenium - if your diet lacks enough zinc and selenium or any other trace elements, toxic heavy metals can take their place. So to protect yourself from the effects of heavy metals, you need to ensure the right dose of trace elements - thanks to this heavy metals will be less likely to replace them during the production of enzymes.
- Glutathione - is a very important detoxification factor of the body.
Vitamin and mineral supplementation can be combined with other chelators.
If we want to use some agent as an adsorbent, we choose one preparation, e.g. chlorella, activated carbon, diatomaceous earth or enterosgel. In addition, during chelation, you can use herbs such as: almond chewbowl, dandelion, small-leaved bacillus, algae, Asian pennywort and Scots pine or pomegranate extract.
 
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Having an excess amount of heavy metals can negatively affect the human body. Some foods and medicines can help remove heavy metals from the body. Using such substances for this purpose is known as a heavy metal detox.
Having small amounts of some heavy metals, such as iron and zinc, is essential for a healthy body. However, having large amounts of heavy metals can be toxic to the body and the environment.
According to a 2019 review, heavy metal poisoning is a common health issue due to the prevalence of industrial, agricultural, and sewage waste.
Certain substances, such as those present in some foods and medications, bind to heavy metals and transport them out of the body. This process is called chelation.
However, unapproved chelation can be dangerous and even fatal. People should not attempt heavy metal detoxes without the supervision of a healthcare professional.
This article looks at the possible benefits of heavy metal detox diets, the evidence behind them, some vital safety considerations, and the possible side effects.
Heavy metal toxicity can affect the function of organs such as the brain, the liver, and the lungs. Having high levels of heavy metals in the body can also reduce energy levels and affect blood composition.
Long-term exposure to heavy metals can cause the symptoms seen in degenerative conditions, such as Parkinson’s disease and Alzheimer’s disease. In some cases, long-term exposure to some metals may even cause cancer.
Everyone has a certain amount of heavy metals in their body. For people with a normal amount, chelation has the potential to cause more harm than good.
Chelation therapy can treat heavy metal poisoning under the careful supervision of a healthcare professional. Using chelation therapy for anything other than extreme cases of heavy metal poisoning can be very dangerous and even fatal.
A person may be able to reduce the levels of heavy metals in their body more gradually by making changes to their diet. Certain foods, such as spirulina and cilantro, may help transport excess heavy metals out of the body.
According to one 2013 review, the following foods may be effective for heavy metal detoxification:
  • Dietary fiber: Various foods rich in fiber, such as fruit and grains with bran, may help remove heavy metals. Researchers have found fiber to reduce mercury levels in the brain and blood.
  • Chlorella: Studies have shown that chlorella increases the detoxification of mercury in mice.
  • Foods containing sulfur: Foods rich in sulfur, such as garlic and broccoli, may be good chelators. Research has suggested that garlic may have prevented kidney damage from cadmium and reduced oxidative damage from lead in rats.
  • Cilantro: Cilantro may help, but there is currently limited evidence to support this. In an animal study, cilantro decreased absorption of lead into bone. In a trial looking at children with lead exposure, cilantro was as effective as a placebo.
The same review also lists some supplements that may work to chelate heavy metals from the body:
  • Glutathione: Certain forms of glutathione, when a person takes it other than orally, may protect cells from the oxidative damage that heavy metals can cause.
  • Modified citrus pectin: Modified citrus pectin and substances from brown seaweeds lowered heavy metal toxicity by roughly 74% in human participants across five case studies.
  • Sulfur-containing amino acids: Examples of these are taurine and methionine.
  • Alpha-lipoic acid: Alpha-lipoic acid is a strong antioxidant that can renew other antioxidants in the body and chelate metals from the body.
  • Selenium: Selenium may help remove mercury from the body. In one trial, organic selenium supplementation benefited people with mercury exposure.
Although these are less extreme methods of detoxifying the body, it is still important to take care when using supplements or excessive quantities of one type of food.
Although dietary fiber may help detoxify the body, one study found that soluble fiber such as flaxseed increased the retention of cadmium in rats. People with high exposure to cadmium may therefore need to exercise caution when consuming flaxseed.
Certain chelators, such as alpha-lipoic acid, can cause the redistribution of metals in the body. People should therefore take care when using certain detoxification substances and always follow the advice of a healthcare professional.
 
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Only some heavy metals are necessary for the proper functioning of living organisms (e.g. copper, zinc), and e.g. cadmium, lead, mercury or arsenic are the cause of many human and animal diseases. The excessive accumulation of these elements in soils and plants was caused by the development of industry and communication as well as irrational use of plant protection products and mineral fertilizers. The most effective method of cleaning up the environment contaminated with heavy metals is obtaining these substances from the soil with the help of plants that are able to grow in conditions of high concentration of toxic substances and accumulate them in their bodies. Particularly interesting in phytoextraction are: reed fescue, reed canary, tall ryegrass, elongated wheatgrass, rosaceae, Gerard's mackerel, sugar miscanthus, compass lettuce, mugwort, Canadian goldenrod and late goldenrod. Different scenarios are possible phytoextraction of heavy metals from contaminated soils and utilization of plants for withdrawal of harmful substances.
 
 
Parisa Ziarati
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Some heavy metals are nutritionally essential elements playing key roles in different physiological and biological processes, like: iron, cobalt, zinc, copper, chromium, molybdenum, selenium and manganese, while some others are considered as the potentially toxic elements in high amounts or certain chemical forms. Nowadays, various usage of heavy metals in industry, agriculture, medicine and technology has led to a widespread distribution in nature raising concerns about their effects on human health and environment. Metallic ions may interact with cellular components such as DNA and nuclear proteins leading to apoptosis and carcinogenesis arising from DNA damage and structural changes. As a result, exposure to heavy metals through ingestion, inhalation and dermal contact causes several health problems such as, cardiovascular diseases, neurological and neurobehavioral abnormalities, diabetes, blood abnormalities and various types of cancer. Due to extensive damage caused by heavy metal poisoning on various organs of the body, the investigation and identification of therapeutic methods for poisoning with heavy metals is very important. The most common method for the removal of heavy metals from the body is administration of chemical chelators. Recently, medicinal herbs have attracted the attention of researchers as the potential treatments for the heavy metals poisoning because of their fewer side effects. In the present study, we review the potential of medicinal herbs such as: Allium sativum (garlic), Silybum marianum (milk thistle), Coriandrum sativum (cilantro), Ginkgo biloba (gingko), Curcuma longa (turmeric), phytochelatins, triphala, herbal fibers and Chlorophyta (green algae) to treat heavy metal poisoning.
Journal of Herbmed Pharmacology
J Herbmed Pharmacol. 2019; 8(2): 69-77
 
Parisa Ziarati
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Some heavy metals are nutritionally essential elements playing key roles in different physiological and biological processes, like: iron, cobalt, zinc, copper, chromium, molybdenum, selenium and manganese, while some others are considered as the potentially toxic elements in high amounts or certain chemical forms. Nowadays, various usage of heavy metals in industry, agriculture, medicine and technology has led to a widespread distribution in nature raising concerns about their effects on human health and environment. Metallic ions may interact with cellular components such as DNA and nuclear proteins leading to apoptosis and carcinogenesis arising from DNA damage and structural changes. As a result, exposure to heavy metals through ingestion, inhalation and dermal contact causes several health problems such as, cardiovascular diseases, neurological and neurobehavioral abnormalities, diabetes, blood abnormalities and various types of cancer. Due to extensive damage caused by heavy metal poisoning on various organs of the body, the investigation and identification of therapeutic methods for poisoning with heavy metals is very important. The most common method for the removal of heavy metals from the body is administration of chemical chelators. Recently, medicinal herbs have attracted the attention of researchers as the potential treatments for the heavy metals poisoning because of their fewer side effects. In the present study, we review the potential of medicinal herbs such as: Allium sativum (garlic), Silybum marianum (milk thistle), Coriandrum sativum (cilantro), Ginkgo biloba (gingko), Curcuma longa (turmeric), phytochelatins, triphala, herbal fibers and Chlorophyta (green algae) to treat heavy metal poisoning
Keywords: Herbal plants Heavy metals Chelation Detoxification
 
Parisa Ziarati
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Abstract:
Environmental pollution is one of the major problems of the world and it is increasing day by day due to urbanization and industrialization. Over the last few decades large scale usage of chemicals in various human activities have thrown very fast, particularly in a country like India which has to go for rapid industrialization in order to sustain over growing large problem of population. The current pattern of industrial activity alters the natural flow of materials and introduces novel chemicals into the environment. The released organic compounds and heavy metals are one of the key factors that exert negative influences on man and environment causing toxicity to plants and other forms of biotics and abiotics that are continually exposed to potentially toxic heavy metals. Of the various sources of pollutants industriel effluents containing heavy metals pose a threat to the ecosystem. These metals are present in the waste water of different industries such as metal cleaning, oil refineries, mining, electroplating, paper and pulp, paint, textile and tanneries. Water used in these industries creates a waste that has potential hazards for our environment because of the introduction of various contaminants such as heavy metals into soil and water. This article briefly describes the possible natural ways to eliminate toxic heavy metals thereby to attain good health.
 
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Elimination: Detoxification Clinical
,Schwalfenberg Gerry
,Sears. E Margaret 1,Genuis. J Stephen Bernhoft3 Robin and 3,Hope Janette 4C1 T6K Canada, AB, Edmonton, Street 66-2935, Alberta of University, Medicine of Faculty 1 8L1 K1H Canada, ON, Ottawa, Institute Research Ontario Eastern of Hospital s’Children 2 USA, 67206 KS, Wichita, Medicine Environmental of Academy
 
Parisa Ziarati
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Abstract
Introduction: There are a number of reports in the literature that discuss the heavy metal chelation properties of various natural substances1–7 Many of these have never been tested systematically using the “gold standard” methodology of the double– blind, placebo controlled trial. Our research group were commissioned by a Russian metal foundry to examine the chelating effects of these natural substances, and attempt to identify a natural compound that would be effective at chelating a number of toxic metals from Russian metal foundry workers. Design, methods and analysis: This was a randomised, double–blind, placebo controlled trial with 350 metal foundry workers using a number of natural substances purported in the literature to chelate heavy metals. Adult males aged 18–60years old were randomly allocated to various groups taking a number of natural substances to determine their chelating potential for heavy metals. Each of these groups consisted of a control as well as an experimental group. ICP–MS pre– and post– analysis of urine, blood and hair samples was carried out over a 3–year period. Discussion: This trial was designed to find the best natural compound that can be safely used for chelating men working in environments that are toxic with heavy metals. If successful, this researched natural compound may play a significant role in the treatment, prevention and general well–being of people working in toxic environments such as metal foundries and other industries with toxic by–products in the environment.
Keywords: heavy metals, toxic metals, natural oral heavy metal chelators, metal detox, mercury detox, heavy metal detox, toxic metal detoxificat
Georgiou Georgiou Da Vinci BioSciences Research Center
 
Barbara Sawicka
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Natural methods for removing heavy metals from the human body include:
• Bee honey, propolis and pollen, which have the ability to eliminate harmful metals from the body, especially heavy metals. Flavonoid compounds found in these products, which form water-soluble connections (chelates) with metals and are thus responsible for this action, are removed from the body. Control tests showed that a diet with the addition of bee products (mainly honey) reduced the average level of lead in blood serum by up to 37%. Propolis quite clearly removes lead from bones (in the range of 21.9–24.4%), as well as from the sciatic nerve (27.1%) and brain (8.5%), which indicates the release of this metal from peripheral and central the nervous system. This is of great practical importance in poisoning these systems with lead, especially in children
 
Parisa Ziarati
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Some foods/ vegetables and crops can help detoxifying and getting rid of heavy metals( Lead, Cadmium, Mercury, arsenic and Nickel ,.......from the body. These foods bind to the metals and remove them in the digestive process.