Project

PLAMORF | Plant Mobile RNAs: Function, Transport and Features

Goal: Shed light on the function, transport and features of plant mobile RNAs. ERC synergy grant project.

Date: 1 April 2019 - 31 March 2024

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Project log

Daniela Fichtenbauer
added an update
The sixth international conference on Plant Vascular Biology takes place in Berlin, Germany from July 17 – 21 2022. The PLAMORF scientists Friedrich Kragler, from the MP-IMP in Golm and Julia Kehr from the University of Hamburg are members of the local organizing committee.
Check the conference website for update on the program, registration and more information: www.pvb2022.org
 
Daniela Fichtenbauer
added an update
Several PLAMORF scientists will present their latest research at the EMBO Workshop: Intercellular communication and plasmodesmata in plant development and disease.
This includes principal investigator Julia Kehr from University of Hamburg, Fritz Kragler from Max-Planck-Institut for Molecular Plant Physiology, Francisca Méndez Pinochet, Saurabh Gupta, Ying Xu, and Frank Machin.
 
Daniela Fichtenbauer
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Daniela Fichtenbauer
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Data mining and analysis, mathematical modelling, machine-learning and ‘omics are transforming how plant research is being done. This is opening a new chapter in our understanding of the complexity behind plant life. Quantitative Plant Biology is a new open acces, not-for-profit journal....
 
Daniela Fichtenbauer
added an update
We just published an aimation explaining the PLAMORF research project funded by ERC/H2020. What is long-distance RNA transport in plants, and why does it matter? Find out more about this specific field of plant science in only 2 minutes in this science communication video!
 
Daniela Fichtenbauer
added an update
Visit our website www.plamorf.eu to read an interview with Richard Morris, group leader at the John Innes Centre, about his team’s work in the first year of PLAMORF, how Covid-19 affects their progress, what is planned next and what makes a good scientist.
 
Daniela Fichtenbauer
added a research item
Secondary base modifications on RNA, such as m 5 C, affect the structure and function of the modified RNA molecules. Methylated RNA Immunoprecipitation and sequencing (MeRIP-seq) is a method that aims to enrich for methylated RNA and ultimately identify modified transcripts. Briefly, sonicated RNA is incubated with an antibody for 5-methylated cytosines and precipitated with the assistance of protein G beads. The enriched fragments are then sequenced and the potential methylation sites are mapped based on the distribution of the reads and peak detection. MeRIP can be applied to any organism, as it does not require any prior sequence or modifying enzyme knowledge. In addition, besides fragmentation, RNA is not subjected to any other chemical or temperature treatment. However, MeRIP-seq does not provide single-nucleotide prediction of the methylation site as other methods do, although the methylated area can be narrowed down to a few nucleotides. The use of different modification- specific antibodies allows MeRIP to be adjusted for the different base modifications present on RNA, expanding the possible applications of this method.
Daniela Fichtenbauer
added an update
Check out our website, that is now online!
 
Daniela Fichtenbauer
added a project goal
Shed light on the function, transport and features of plant mobile RNAs. ERC synergy grant project.