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Plants are rich sources of bioactive compounds, and have been used in traditional medicine systems for the past few millennia; even now plant-based drugs continue to provide new remedies to mankind. The medicinal plant Alstonia scholaris (L.) R. Br. (Saptaparṇa, Chhatim) is widely used in the Indian school of traditional medicine of Ayurveda. The present study reports phytochemical studies and HPTLC fingerprinting profile of Alstonia scholaris roots. These results provide referential parameters for identification of this drug.
A new steroid, designated Alru-1, isolated from the hexane extract of Ailanthus excelsa Roxb, has been characterised from spectroscopic analysis and chemical transformation as stigmasta-4, 22-dien-3-ol.
Three indole alkaloids have been isolated from Alstonia macrophylla Wall. Two of these have been identified as affinisine (I) and picrinine (II). The third, a new base designated picralstonine, has been shown to possess structure (III).
Dipolar cycloaddition reactions of chalcones with non-stabilized azomethine ylides formed in situ from L-proline and aldehydes are studied.