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Metabolic syndrome

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Madhumita Panigrahi
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In last a few decades, market of herbal and traditional medicines have grown up leap and bound. The main drawback of traditional medicines is a lack of stability. Hence the present Study was carried out to observe the stability of Bhringraj Vati (Eclipta alba Hassk) & Triphala Gugulu with respect to its stability against microbial contamination of sample prepared and store in different climatic conditions and temperature. Sample of Bhringraj Vati & Triphala Gugulu were prepared and studied to check microbial contamination at regular time intervals. A baseline Microbial profile was studied at regular interval of 1 month for total 7 months (i.e. time for consumption of prepared drug). Every time sample was subjected to the microbiological study from the date of the preparation to the date of last microbiological study. In microbiological study of both the drugs, there were no growth found of microorganisms (bacterial or fungal) till26 th Feb 2019 i.e. 268 days from the date of preparation, shows its stability and good shelf life. Hence in present study the stability test of Bhringraj Vati & Triphala Gugulu with respect to microbiological findings was negative at room temperature, warm and cold, dry and humid conditions.
Madhumita Panigrahi
added 3 research items
Hair fall is a universal problem, having affected both sexes of all races to different extents for as long as mankind has existed. For thousands of years, men and women of all countries and races have shared the tragedy of premature hair loss. In Ayurveda, disease Khalitya (Hair fall) comes under the caption of Shiroroga and Kshudrarogaby various Acharya. The faulty hair care methods, dislikes to apply hair oil, excessive use of various type of hair cosmetics like hair colour, cream, dye, gel, chemical shampoos, soaps, etc., excessive use of hair equipment along with faulty dietetic habits and life style, pollution, hormonal imbalances, etc. are the common causes of Khalitya. A 28 years old female patient came to OPD of department of Basic Principle with chief complaints of Khalitya (Hair Falling), Shirah Kandu (Itching on Scalp), Kesha Rukshata (Dryness of Hair), Kesha Kathinya (Harshness of Hair), Kesha Tanutva (Thinness of Hair). In this case Bhringraj Vati as oral medication, coconut hair oil as external application followed by washing the hair with a supplied neutral shampoo were advised. The improvement provided by the therapy was assessed on the basis of signs and symptoms before and after treatment. A special scoring pattern was developed for assessing signs and symptoms. The medication was found safe and effective in controlling hair fall and improving the overall condition of hair.
Background: Since the past decades, there has been increasing acceptance and public interest in herbal products and therapies in both developing and developed countries. So, we cannot assure pharmaceutical industries insulation from adulterations and quality decrement. Therefore, quality control for efficacy and safety of herbal products is at prime concern. Bhringraj is a plant of immense value. It is a plant from the family Asteraceae. Besides curing diseases it also improves general health. Bhringaraj Vati is not mentioned in any classics. It is an Anubhuta drug formulated for the treatment of metabolic syndrome. Objective: The present study is aimed at setting up a standard profile of Bhringaraj Vati through Pharmacognostical and Physicochemical parameters. Methods: Raw drugs identification and authentication was done by pharmacognostical study i.e. morphological features, organoleptic characters and powder microscopy. Physicochemical evaluation was carried out of final product. Results & conclusion: Pharmacognostical study of raw drugs showed presence of starch grain, trichome with smooth surface, collapse spongy parenchyma, fibers with wide lumen, micro-crystals etc. Pharmaceutical evaluation showed results PH 7,loss on drying 7.5%w/w, Ash value 35%w/w, Acid insoluble ash 19.5%w/w, Water soluble extract 15.9%w/w, Methanol Soluble Extract 9.36 %w/w, Hardness 2.35 kg/cm2. The result of present study will also serve as reference standards in the preparation of drug formulation.