Project

Hot Solute

Goal: The HotSolute project aims to provide small molecular compounds so called “extremolytes”, which stabilize cells and their cellular structures under extreme conditions, for biotechnological applications. Extremolytes cannot be produced in the available mesophilic production hosts and therefore two thermophilic hosts, Thermus thermophilus and Sulfolobus acidocaldarius of bacterial and archaeal origin, respectively, will be established as novel platform organisms. Extremolytes possess great potential for application in the cosmetic and health care market.

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Project log

Benjamin H. Meyer
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The HotSolute project aims to provide small molecular compounds so called “extremolytes”, which stabilize cells and their cellular structures under extreme conditions, for biotechnological applications. Extremolytes cannot be produced in the available mesophilic production hosts and therefore two thermophilic hosts, Thermus thermophilus and Sulfolobus acidocaldarius of bacterial and archaeal origin, respectively, will be established as novel platform organisms. Extremolytes possess great potential for application in the cosmetic and health care market.