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The technical requirements and hygiene standards for the buildings and internal building installations of the medical establishments provided in various normative documents are considered. Fulfillment of these requirements would increase the readiness of medical institutions to isolate a (suspected) patient with an airborne infection (such as Severe Acute Respiratory Syndrome and/or COVID-19), in order to prevent the spread of infection among staff, other patients and visitors, especially those with reduced immunity or falling into another risk group group vulnerable to various pathogens transmitted in the hospital environment.. We mainly focus on Ordinance № RD-02-20-3 of the Ministry of Regional Development and Public Works of 21.12.2015 for design, implementation and maintenance of public service buildings in the field of education and science, healthcare, culture and arts, , as well as the Medical Standard on prevention and control of hospital-acqiured infections, approved by Ordinance № 3 of 08.05.2013 of the Ministry of Health. Bringing isolation rooms or parts of buildings of medical institutions in the country to the cited requirements would increase their readiness for early response in epidemic situations related to airborne infections.