Zoë Hyde

Zoë Hyde
University of Western Australia | UWA · Western Australian Centre for Health and Ageing

MPH PhD

About

67
Publications
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2,468
Citations

Publications

Publications (67)
Article
Full-text available
It is widely thought that children are much less susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection than adults and do not play a substantial role in transmission. However, emerging research suggests this perception is unfounded. Seroprevalence and contact tracing studies show children are similarly susceptible an...
Article
Multi-layered mitigations can substantially reduce the risk of transmission within schools and into households. We summarise a set of recommendations that are in line with guidelines from the US Centers for Disease Control and Prevention (CDC) and practised in many countries to reduce the risk of transmission in schools and mitigate the impact of C...
Article
Full-text available
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the coronavirus disease 2019 (COVID-19) pandemic, is believed by many to be transmitted via respiratory droplets and fomites, with occasional airborne transmission observed in the setting of aerosol generating procedures. However, research shows viable SARS-CoV-2 can be dete...
Article
Objectives To investigate whether diabetes and obesity are associated with frailty independently, and to determine the proportion of frailty cases attributable to each factor. Study design Prospective cohort study of 4219 older men assessed in 2001–04 (time-point 1, T1), of whom 1939 were reassessed in 2008–09 (time-point 2, T2). Frailty was defin...
Article
Full-text available
Objective To offer a quantitative risk–benefit analysis of two doses of SARS-CoV-2 vaccination among adolescents in England. Setting England. Design Following the risk–benefit analysis methodology carried out by the US Centers for Disease Control, we calculated historical rates of hospital admission, Intensive Care Unit admission and death for as...
Preprint
Full-text available
The UK JCVI committee recently announced that vaccines would not be offered to all 12-17 year olds, as the potential risks were not outweighed by the benefits. Here, we offer a quantitative risk-benefit analysis of vaccines among 12-17 year olds in England, showing that the benefits of vaccination greatly outweigh risks among 12-17 year olds in Eng...
Preprint
On 22nd February, the UK government announced schools in England would fully reopen on the 8th March 2021. While returning to school as soon as possible is imperative for the education, social development, and mental and physical welfare of children, not enough has been done to make schools safer for students and staff. Multi-layered mitigations ca...
Article
Full-text available
The epidemiology of coronavirus disease 2019 in children has been challenging to establish, owing to the high prevalence of asymptomatic infection in this population. Lower secondary attack rates in children compared with adults have been observed in household contact studies, but there is evidence that this may reflect lower testing in children an...
Article
Enhancing quality of life (QoL) is the primary goal of aged care services for older people with dementia. Despite this, there are no culturally appropriate QoL measures for older Indigenous peoples with or without dementia. This study aims to address this gap. The Good Spirit, Good Life (GSGL) tool was co‐developed with older Aboriginal Australians...
Article
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 35 million people globally, with more than 1 million deaths recorded by WHO as of Oct 12, 2020. As a second wave of COVID-19 affects Europe, and with winter approaching, we need clear communication about the risks posed by COVID-19 and effective strategies to combat...
Preprint
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In their recent paper, Viner and colleagues aimed to determine the susceptibility of children and adolescents to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and concluded they are less susceptible than adults. While the authors are to be commended for investigating this important topic, many of the studies reviewed are l...
Preprint
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Lavezzo and colleagues recently conducted a prevalence survey of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the Italian municipality of Vo’. While their work provides valuable evidence that the epidemic can be successfully controlled with non-pharmaceutical interventions, the authors reported an unusually high proport...
Preprint
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To the Editor: In their recent review, Oran and Topol (1) aimed to determine the prevalence of asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and concluded 40-45% of infected persons likely remain symptom-free. Although the authors attempted to distinguish between pre-symptomatic cases (i.e., those yet to devel...
Article
Background Pain is a growing public health problem associated with significant health and functional implications. Limited data exist for Aboriginal Australians. Aim To describe the prevalence, severity and sites of pain, analgesic use, and associated factors including depression and disability, in remote‐living Aboriginal Australians. Methods Cr...
Article
Objective: To describe demographic features and well-being of carers of Aboriginal Australians aged ≥45 years in remote Western Australia. Method: Carer burden, empowerment, and depression were assessed in 124 Aboriginal carers in four remote Aboriginal communities. Results: Carers were aged 38.8 ± 15.0 years, 73.4% were female, and 75.8% were chil...
Article
Full-text available
Objectives To investigate the prevalence of polypharmacy, under‐prescribing and potentially inappropriate medicine use among Aboriginal Australians living in remote Western Australia. Design Cross‐sectional study. Setting Six remote communities and the town of Derby in the Kimberley, Western Australia. Participants Aboriginal people aged 45 year...
Article
In this cross-sectional study of 141 Aboriginal Australians aged ≥45 years living in the remote Kimberley region of Western Australia, we explored whether glycated haemoglobin (HbA1c) levels were associated with frailty. Sixty-four participants (45.4%) had a HbA1c level ≥6.5% and 84 participants (59.6%) were frail. A significant trend was observed...
Article
Background Little is known about urinary incontinence in older Aboriginal Australians. Aim To describe urinary incontinence assessment, prevalence, incidence, and associated conditions in older Aboriginal Australians. Methods Wave 1 consisted of 363 Aboriginal participants aged ≥45 years from Western Australia. 289 participants participated in Wa...
Article
Full-text available
Objectives We aimed to describe mortality in a cohort of remote-living Aboriginal Australians using electronic record linkage. Methods Between 2004 and 2006, 363 Aboriginal people living in remote Western Australia (WA) completed a questionnaire assessing medical history and behavioural risk factors. We obtained mortality records for the cohort fr...
Data
Kaplan-Meier survival curves showing associations between age and all-cause mortality. (PNG)
Article
Objective: To describe the prevalence of falls and associated risk factors in older Indigenous Australians, and compare the accuracy of validated falls risk screening and assessment tools in this population in classifying fall status. Method: Cross-sectional study of 289 Indigenous Australians aged ≥45 years from the Kimberley region of Western...
Article
Objectives: Frailty represents a loss of homeostasis, markedly increasing the risk of death and disability. Frailty has been measured in several ethnic groups, but not, to our knowledge, in Aboriginal Australians. We aimed to determine the prevalence and incidence of frailty, and associations with mortality and disability, in remote-living Aborigi...
Article
Aboriginal Australians are reported to develop dementia earlier than the general population. The causes remain unknown. This was a longitudinal study of 363 participants aged ≥45 years. Consensus diagnoses were established for cognitive impairment or dementia. At follow-up, 189 people (mean ± standard deviation age, 65.4 ± 10.3 years) participated,...
Article
Full-text available
Context and objective Prostate, colorectal and lung cancers are common in men. In this study, we aimed to determine whether vitamin D status is associated with the incidence of these cancers in older men. Design Prospective cohort study. Setting and participants 4208 older men aged 70–88 years in Perth, Western Australia Main outcome measures Pl...
Article
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This study aimed to develop a culturally acceptable and valid scale to assess depressive symptoms in older Indigenous Australians, to determine the prevalence of depressive disorders in the older Kimberley community, and to investigate the sociodemographic, lifestyle and clinical factors associated with depression in this population. Cross-sectiona...
Article
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Background: Population-based studies, as well as clinicians, often rely on self-report and hospital records to obtain a history of stroke. This study aimed to compare the validity of the diagnosis of stroke by self-report and by hospital coding according to their cross-sectional association with prevalent vascular risk factors, and longitudinal as...
Article
The aim of the present study was to assess whether peripheral arterial disease is associated with an increased risk of hip fracture in a cohort of 12,094 older men. There was no association between claudication and hip fracture, but there was a significant association with an ankle brachial index (ABI) <0.9. Introduction It is uncertain whether per...
Article
The relationship between testosterone and cancer is relatively unexplored. We sought to examine whether testosterone and related hormones are associated with incident prostate, lung, and colorectal cancer. This was a population-based cohort study. Demographic and clinical predictors of cancer, and testosterone, sex hormone-binding globulin (SHBG),...
Article
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Low testosterone is associated with all-cause mortality, but the relationship with cause-specific mortality is uncertain. Our objective was to explore associations between testosterone and its related hormones and cause-specific mortality. This was a population-based cohort study. Demographic and clinical predictors of mortality, and testosterone,...
Article
Hypogonadism is associated with impaired libido and erectile dysfunction in young men, but the causes of sexual dysfunction in older men are less well understood. To determine the prevalence and predictors of sexual problems in older men. Sexual problems, as assessed by a self-reported questionnaire. This was a population-based, cohort study of 3,2...
Article
To determine the prevalence of potentially suboptimal medication use and association with adverse outcomes. A prospective, observational cohort study of 4260 community-dwelling older men from Perth, Western Australia (mean age of 77 ± 3.6 years) was conducted. Follow-up was for 4.5 years (or until death, if sooner). Cox proportional hazard models w...
Article
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Hypogonadism in men is associated with insulin resistance, elevations in pro-inflammatory cytokines and fibrinogen, and an atherogenic lipid profile. However, it is uncertain whether the age-related decline in testosterone is associated with ischaemic heart disease (IHD) events. To determine whether testosterone and its associated hormones, sex hor...
Article
Knowledge about sexuality in elderly persons is limited, and normative data are lacking. To determine the proportion of older men who are sexually active and to explore factors predictive of sexual activity. Population-based cohort study. Community-dwelling men from Perth, Western Australia, Australia. 3274 men aged 75 to 95 years. Questionnaires f...
Article
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The prevalence of frailty increases, whereas testosterone decreases, as men age. Low testosterone may be a risk factor for development of this syndrome. Our objective was to determine whether testosterone levels are associated with frailty. We conducted a prospective cohort study. Between 2001 and 2004, frailty was assessed in 3616 community-dwelli...
Article
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To assess the prevalence of and risk factors for claudication and its association with subsequent cardiovascular events. Observational cohort study of 12 203 Western Australian men aged 65 years and over, recruited from 1996 to 1999, and followed up from 2001 to 2004. Prevalence of claudication and incidence of peripheral arterial disease (PAD); ri...
Article
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Context: Abdominal aortic aneurysm (AAA) is associated with mortality in older adults, and increasing aortic diameter predicts incident cardiovascular events. Although AAA occurs predominantly in men, its association with male sex hormones is unclear. Objective: The objective of the study was to examine whether male sex hormones are independentl...
Article
Elevated levels of gonadotropins have been observed in patients with Alzheimer's disease and have been associated with poorer cognition in women, but not men. The aim of this study was to explore the relationship between gonadotropins and cognition in a cohort of 585 healthy, community-dwelling men aged 70-87 years. Cognitive function was assessed...
Article
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The prevalence of alcohol, tobacco and illicit drug use has been reported to be higher amongst lesbian and bisexual women (LBW) than their heterosexual counterparts. However, few studies have been conducted with this population in Australia and rates that have been reported vary considerably. A self-completed questionnaire exploring a range of heal...
Article
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Insulin resistance is associated with metabolic syndrome and type 2 diabetes, representing a risk factor for cardiovascular disease. This relationship may be modulated to some extent by age-related changes in sex hormone status. We examined whether lower testosterone or sex hormone-binding globulin (SHBG) levels in older men are associated with ins...
Article
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Lower circulating testosterone concentrations are associated with metabolic syndrome, type 2 diabetes, carotid intima-media thickness, and aortic and lower limb arterial disease in men. However, it is unclear whether lower testosterone levels predict major cardiovascular events. We examined whether lower serum testosterone was an independently sign...
Article
Circulating testosterone declines during male ageing, and low testosterone may predispose to ill health. We sought to determine whether greater participation in healthy behaviours predicted reduced risk of subsequent lower circulating testosterone in older men. Cross-sectional analysis of a population-based follow-up study. A total of 3453 men aged...
Article
Full-text available
Reduced circulating testosterone and sex hormone-binding globulin (SHBG) are implicated as risk factors for metabolic syndrome. As SHBG increases with age while testosterone declines, we examined the relative contributions of SHBG and testosterone to the risk of metabolic syndrome in older men. We conducted a cross-sectional study of 2502 community...
Article
To determine the relationship of total and free serum testosterone to cognitive performance in older men. Cross-sectional study of a population-based sample. Participants A total of 2932 men aged 70-89 years. Cognitive function was assessed using the Standardized Mini-Mental State Examination (SMMSE). Early morning sera were assayed for total testo...
Article
Full-text available
An age-related decline in serum total and free testosterone concentration may contribute to ill health in men, but limited data are available for men > 70 years of age. We sought to determine the distribution and associations of reduced testosterone concentrations in older men. The Health in Men Study is a community-representative prospective cohor...
Technical Report
Major aims of the study were to provide a broad overview of the health status of lesbian and bisexual women; supply guidance to future health promotion programs targeting this population; and to provide a starting point for further in-depth research. Where appropriate, data are contrasted with the 2004 National Drug Strategy Household Survey, age-w...

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