Ziba Farajzadegan

Isfahan University of Medical Sciences · Community Medicine Department

Background The objective is to summarize evidence from systematic reviews, scoping reviews, and meta-analyses evaluating the effects of any format of Internet-based, mobile-, or telephone-based intervention as a technology-based intervention in suicide prevention. Materials and Methods This is an umbrella review, that followed Preferred Reporting...

In recent years, research on the competing endogenous RNAs (ceRNAs) in cancer is in full swing. These investigations are discovering the importance of critical RNAs in cancer progression. Enhancer of zeste 2 polycomb repressive complex 2 subunit ( EZH2 ) is one of these RNAs that has been identified as a potential therapeutic target in many types o...

Background Meat and meat products are introduced as one of the frequent sources of Clostridioides difficile. We aimed to determine the prevalence and antibiotic resistance of C. difficile isolates in meat and meat products using a systematic review and meta-analysis. Methods A literature search was performed in the primary international and biblio...

Purpose To systematically review the published manuscripts on the non-steroidal intravitreal injection for treatment of noninfectious uveitic cystoid macular edema (CME). Methods The PubMed, Scopus, and Web of Science, Science Direct, ProQuest, Cochrane Library, ProQuest, Embase, Clinical Key, and Springer were searched for relevant articles publi...

Background: Psychosomatic medicine is a systemic model of care based on the biopsychosocial model in which the physical, emotional, and social aspects of clinical conditions are considered. Family Medicine (FM) and psychosomatic medicine have many similarities in their community-based and family-based approaches. Studies have shown the necessity an...

Background: Violent behavior in adolescents is one of the important public health problems; however, studies on this issue in developing countries are limited. Nowadays, adolescents spend a lot of day-night time watching TV. Objectives: The aim of this study was to evaluate the relationship between watching violent movies and perpetrating violent b...

Background: Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder among women of reproductive years. In addition to multiple physical problems, this syndrome has many psychological complications. Thus, the present study attempted to explore the psychological experiences of women with PCOS in Iran's sociocultural context. Material...

Background Meniere’s disease (MD) is a complex disease that can severely affect the quality of life. In this systematic review and meta-analysis, we aimed to investigate the effect of vestibular rehabilitation (VR) versus control/other interventions on the quality of life in patients with MD. Methods We searched six electronic databases (PubMed/ME...

Introduction With an increasing rate of population aging and its consequences, preparation for active aging based on older adults' needs is an unavoidable priority. Active aging needs must be identified to help strategic planning for older adults' health and wellbeing. This study aimed to explore the active aging needs from the perspectives of olde...

With an increase in the older adult population, many countries have designed programs to promote active aging. Thus, knowledge of the factors and features of these programs is necessary to design a comprehensive active aging program. This study aimed to review the active aging programs focusing on the extraction of essential factors, key features,...

Aims: Gastric cancer (GC) represents a global health-care challenge. In recent years, a large number of competing endogenous RNA (ceRNA) network studies have elucidated critical long non-coding RNAs (lncRNAs) as potential prognostic biomarkers in GC. Nevertheless, there is no systematic review and meta-analysis regarding them. Here, we propose a sy...

Background Dramatic body changes in pregnancy cause severe concerns among pregnant women about their appearance. Therefore, this study aimed to explore body perception in pregnant women. Materials and methods The qualitative study, using the conventional content analysis approach, was conducted on Iranian pregnant women who were in their second or...

Background and purpose: Thoracic hyperkyphosis may adversely influence physical function in older adults, but the literature is mixed and confounded by possible sex differences. This systematic review and meta-analysis aimed to examine the association between hyperkyphosis and physical function in older females. Methods: Scopus, ISI Web of Scien...

Background: The aim of the present systematic review and meta-analysis was to evaluate the therapeutic efficacy of bosentan, a dual endothelin receptor antagonist, for systemic sclerosis (SSc) patients with digital ulcers (DUs). Materials and methods: A systematic search of MEDLINE, Embase, Web of Science, and Scopus was done using appropriate k...

Background: Dramatic body changes in pregnancy cause severe concerns among pregnant women about their appearance. Therefore, this study aimed to explore body perception in pregnant women. Material and methods: The qualitative study, using the conventional content analysis approach, was conducted on Iranian pregnant women who were in their second or...

Lifestyle modification in women with polycystic ovary syndrome (PCOS) could be associated with increased psychological symptoms. This study aimed to evaluate the effect of lifestyle modification counseling using 5A’s model on the psychological symptoms of women with PCOS. This double-blind, randomized field trial was performed on 70 women with PCOS...

This study aimed to compare the non-acid nucleic blood multi-factor panels together and with mammography in terms of sensitivity, specificity, and accuracy in primary breast cancer detection (I, II, III, and IV). We systematically reviewed studies assessing non-acid nucleic blood tumor markers panels' diagnostic value in both healthy women and pati...

Background: This meta-analysis was performed to investigate the effect of serum lipids on the risk of breast cancer incidence. Methods: PubMed, Web of Science, Scopus, and EMBASE were searched systematically from January 1998 to April 2019. Inclusion criteria were English observational studies (cohort or case-control) and the concentration of at...

BACKGROUND: Surrogacy has become an alternative family formation option for women who are unable to carry a pregnancy. There is no comprehensive care program despite the different nature of this pregnancy. The present study aimed to develop a reproductive health-care program for surrogate mothers within the cultural and social context of Iran. MATE...

Background: Castor oil is used in some countries to induce labor, but results on its effectiveness and safety is controversial. This systematic review and meta-analysis aimed to evaluate the effect of castor oil on labor induction and prevalence of vaginal delivery along with investigating its safety. Materials and methods: PubMed, Scopus, Web o...

Background Despite the fact that women with polycystic ovary syndrome (PCOS) experience many psychological problems, the need of these women to planning appropriate to improve their mental health seems to be ignored. Therefore, this study will conduct to exploring needs of women's with PCOS using a qualitative approach in Iranian sociocultural cont...

Introduction: Scientific studies confirm that unhealthy habits play an important role in the development of various disorders in all age groups. The field of medicine is a challenging period for students of this field that causes unwanted changes in their health habits and lifestyle. Objectives: The aim of this study is the evaluate and compare the...

Lifestyle modification in women with polycystic ovary syndrome (PCOS) could be associated with an increase in psychological symptoms. The aim of this study was to evaluate the effect of lifestyle modification counseling through using 5As Model on the psychological symptoms of women with PCOS. This double-blind randomized field trial was performed o...

Background Minimizing costs associated with the care of patients undergoing total knee arthroplasty (TKA) can reduce the burden on health systems that regularly struggle with limited resources. Predicting and reducing TKA associated length of stay (LoS) can therefore be invaluable. This study aimed to determine the factors that impact LoS in patien...

Background: There was the association between the metabolic syndrome (MS) and obstructive sleep apnea (OSA). Also, the genetic factors have been implicated in the OSA. Our aim was to compare the frequency of MS in first-degree relatives (FDRs) of OSA patients with healthy controls. Methods: 39 FDR (parents, siblings, and children) of patients di...

Objective: Granulomatosis with polyangiitis (GPA), formerly known as Wegner's granulomatosis, is a rare vasculitic syndrome classified under Anti-Neutrophilic Cytoplasmic Autoantibody (ANCA)-associ- ated vasculitides, which is fatal if untreated. The mainstay of treatment consists of immunosuppression using a combination of corticosteroids with ei...

This study is aimed at determining the best nonacid nucleic blood tumor marker panels in terms of sensitivity, specificity, and accuracy in order to detect breast cancer in early stages (I, II, and III) among eligible women for breast cancer screening. PubMed, Web of Science, Embase, Scopus, and Cochrane were systematically reviewed to assess nonac...

Hypercholesterolemia is a significant risk factor for heart disease. The soluble fiber in oat (Avena sativa L.), beta-glucan has been shown to significantly lower serum total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) levels but not triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C) according to previous studi...

Introduction: In recent years, the survival rate of breast cancer increases due to improvement in early detection and curative therapies and it highlights the importance of supportive care. The focus of supportive care is on well-being and bettering patient's Quality of life. Sense of coherence (SOC) is a factor enhancing the QOL. SOC represents...

Objective The current study aims to investigate high- versus low-dose dexamethasone administration to control the disease with minor complications. Methods The current multicentric randomized clinical trial was conducted on 119 patients with COVID-19 pneumonia and assigned into two groups of low-dose (8 mg daily intravenous dose for at least 7 day...

Introduction: In recent years, the survival rate of breast cancer increases due to improvement in early detection and curative therapies and it highlights the importance of supportive care. The focus of supportive care is on well-being and bettering patient's Quality of life. Sense of coherence (SOC) is a factor enhancing the QOL. SOC represents pa...

Introduction and hypothesisTo study the mid-term safety and functional outcomes of transvaginal anterior vaginal wall prolapse repair using polyvinylidene fluoride (PVDF) mesh (DynaMesh®-PR4) by the double trans-obturator technique (TOT).Methods Between 2015 and 2020, we prospectively included women with symptomatic high-stage anterior vaginal wall...

Introduction and hypothesis To study the mid-term safety and functional outcomes of transvaginal anterior vaginal wall prolapse repair using polyvinylidene fluoride (PVDF) mesh (DynaMesh®-PR4) by the double trans-obturator technique (TOT). Methods Between 2015 and 2020, we prospectively included women with symptomatic high-stage anterior vaginal w...

Objective: In this study, we evaluated the predictive factors for the occurrence of metabolic acidosis in patients with multi-drug poisoning, including antidepressants (Ad)/antipsychotics (Ap). Methods: This cross-sectional study was carried out in the referral poisoning center, Khorshid University Hospital, affiliated with Isfahan University of...

Introduction: The interaction between angiotensin-converting enzyme 2 (ACE2) and SARS-CoV-2 is a crucial factor in the viral infections leading to the release of inflammatory proteins, such as TNF-α. Thus, it is hypothesized that TNF-α blockers can prevent either COVID-19 incidence or its serious symptoms. TNF-α blockers are prescribed to treat va...

The relationship between the level of consciousness and other symptoms of poisoning and therapeutic outcome in patients poisoned with oral valproic acid.

Background: The cardiovascular mortality rate in Iran has been reported 65% of all death recently. Despite the high prevalence of cardiovascular diseases (CVD) risk factors and its burden in developing countries, public awareness of CVD symptoms and its risk factors are very low, leading to poor control of these risk factors. Methods: Our study...

Genistein, an isoflavone in soybean products has potential cardio-protective effects and is used also as an alternative for estrogen therapy in postmenopausal women. However, results in this regard are inconsistent and also, not all risk factors related to cardiovascular supportive effects have been meta-analyzed. We searched PubMed, Scopus, ISI We...

Introduction: Rheumatoid arthritis (RA) is a systemic autoimmune disease with substantial morbidity and mortality. Anti-malarial drugs like hydroxychloroquine are indicated in several rheumatic diseases such as RA. Some reports have suggested hydroxychloroquine for prevention of COVID-19. Objectives: Whether hydroxychloroquine has prophylactic effe...

Introduction

Objective: Opioids poisoning is of the most important cause of mortality. The objective of the study was to compare the demographic factors, clinical manifestations, and outcomes of the most common opioids involved in drug overdose presenting to the Emergency Department. Methods: This cross-sectional study was conducted from October 2016 to Marc...

Abstract Background Men’s participation in perinatal care is one of the key factors in promoting maternal and neonatal health. The effects of various methods of training on men’s knowledge and attitude about participation in perinatal care can be different. So, this study aimed to compare the effect of two methods of training on men’s knowledge and...

Introduction : Concomitant onset of active systemic lupus erythematosus (SLE) and psoriasis is rare; however, due to the common skin involvement in both and exacerbation of psoriasis with antimalarial medications used for SLE, it is crucial to investigate the concomitant occurrence of both diseases. Objectives : The present study aims to investigat...

Background: Quality of life among cancer patients after diagnosis and treatment steps is an important factor in preventing further cancer complications. Thus, appropriate tools to evaluate the quality of life among this group are required. Quality of life in Adult Cancer Survivors (QLACS) questionnaire is a suitable tool which evaluates different a...

Maternal smoking during pregnancy has detrimental effects on fetal development. The current review examined the differences in offspring’s bone mineral density (BMD) between mothers smoked during pregnancy and those who did not. A systematic review and meta-analysis on the studies investigating the influence of maternal smoking during pregnancy on...

This study aims to review the epidemiological studies on the association between cadmium (Cd) exposure during pregnancy and neonatal anthropometric measures. Electronic search of PubMed, Scopus, Web of Science, and Cochrane Collaboration was conducted till end of 2018. Pooled estimates were performed using a fixed-effects model or random-effects mo...

Background: The incidence of overweight and obesity in children has increased in recent decades. Physical activity (PA), which is a multidimensional behavior, has an important role in preventing and decreasing obesity. The aim of the study is to evaluate the knowledge, attitude, and exercise habits of middle school students and also explore the di...

Introduction: Concomitant onset of active systemic lupus erythematosus (SLE) and psoriasis is rare; however,due to the common skin involvement in both and exacerbation of psoriasis with antimalarial medicationsused for SLE, it is crucial to investigate the concomitant occurrence of both diseases. Objectives: The present study aims to investigate th...

Objective: The climacteric adjustment questionnaire (CAQ) was developed to assess the adjustment with fertility changes in middle-aged women. The aim of this study was to examine the psychometric properties of the CAQ in a sample of Iranian middle-aged women. Method: This study used the impact item method and exploratory factor analysis (EFA) to...

Introduction: Husband’s addiction often leads to the disruption of family roles and duties. In this process, women as wives in families with addicted husbands may tolerate pressures from everywhere and are emotionally, physically, mentally, and behaviorally at risk. Objective: Armed with a qualitative approach, the present study tries to recognize...

This study was conducted with the aim of developing and psychometric evaluation of prenatal body image questionnaire in Farsi language. For preparation of the prenatal body image questionnaire, psychometric steps were performed on a questionnaire based on the results of a qualitative study. Construct validity was evaluated in a cross-sectional stud...

Background: The aim of the present study is identifying the outputs of middle-aged health checks program (MAHCP) in Isfahan province in central of Islamic Republic of Iran. Methods: This is a cross-sectional study. During 30 months, from March 2014 to September 2016, 30-59 years old females and males were screened for abdominal obesity, overweig...

Background Currently, various forms of non-invasive respiratory support have been used in the management of respiratory distress syndrome (RDS) in preterm neonates. However, nasal high-frequency oscillatory ventilation (nHFOV) has not yet been applied commonly as an initial treatment. Objectives This study was designed to investigate the efficacy...

Background There is a belief that in patients with acromegaly, first-generation somatostatin analogs (SSAs) might improve cardiovascular (CV) structure and function. However, most published clinical trials involved only a few patients and their results are rather variable. We aimed to conduct a systematic review on available studies on the impact o...

Background: Anthropometric indices have a debatable relationship with breast cancer (BC) among different ethnicity. In the current study, we have evaluated the relationship between anthropometric indices and BC in Iranian participants. Methods: Between 2012 and 2014, a total of 7,805 women were enrolled from different mammography centers in Isfahan...

Introduction: Statin family drugs are lipid-lowering agents with anti-inflammatory effects. Objectives: The aim of our study was to evaluate anti-inflammatory effects of different statins in rheumatoid arthritis patients. Patients and Methods: Around 161 eligible subjects with rheumatoid arthritis were enrolled. They randomly were divided into thre...

Background Gestational surrogacy is one of the options for women whom pregnancy is contraindicated. Despite of increasing demand for gestational surrogacy, its various aspects are controversial. The unique nature of surrogacy causes surrogate mothers to face a variety of problems such as, ethical confusion, psychological disturbance and reproductiv...

Background Mechanical ventilation (MV) is a life-saving intervention that should be considered for patients with respiratory failure. This study was conducted to evaluate the predictive value of physiologic dead space for weaning success and compare it with rapid shallow breathing index (RSBI). Materials and Methods This cross-sectional study was...

Background: Most of patients with Obstructive Sleep Apnea (OSA) are at risk of metabolic syndrome. The treatment of choice for OSA patients is the Continuous Positive Airway Pressure (CPAP). Reports about the effect of CPAP on metabolic parameters are controversial. So, we aimed to evaluate the effect of CPAP therapy on blood pressure, Fasting Blo...

Background Paraquat (PQ) poisoning is a serious public health problem in many countries. In spite of different treatments, the mortality is still high. We performed a meta-analysis to see whether hemoperfusion (HP) in combination with other treatments reduces the mortality more than HP alone in patients with PQ poisoning. Materials and Methods We...

Background The role of men’s participation in prenatal, delivery and postpartum care is very important, well defined and cannot be over emphasized. Very few studies exist about men’s role in promoting the health of the mother and barriers to their participation in perinatal care in Iran; hence, the present study was conducted to determine the barri...

Background Investing in adolescent’s health, especially, the role of girls in community health and future generations is one of the most important strategies of the Millennium Development Goals. In this regard, supplying adolescents’ special needs including access to educational, health and counseling services for promoting reproductive health have...

Background: The aim of this study was to evaluate the prevalence of positional obstructive apnea among the patients with obstructive sleep apnea (OSA) and its difference in terms of clinical and baseline factors in patients. Methods: This prospective cross-sectional study was conducted on 130 patients with OSA referred to Bamdad Respiratory and Sl...

Background Youth violence is an important public health challenge, and the literature on this problem in developing countries has been limited. The present study aims to determine the prevalence of violence its related risk factors in in a sample of students in Isfahan, Iran. Materials and Methods In this cross-sectional study, 2800 middle and hig...

Background Hepatitis C virus (HCV) infections remain as one of the major public health problems worldwide. The current study aimed at investigating the potential risk factors of HCV+ in a sample of Iranian patients. Materials and Methods In a case–control study, 436 HCV-infected patients and 531 age-matched HCV antibody negative controls were recr...

Background There have been studies on the outcome of acute intoxication with antidepressants or antipsychotics. We performed outcome prediction analysis in acute poisoning patients with antidepressants/antipsychotics with or without combination with other drugs. Materials and Methods A cross-sectional study was performed in Khorshid (PBUH) Univers...