Zhikal Omar Khudhur

Ishik University · Medical analysis

Objectives The genetic polymorphisms of the endothelial nitric oxide synthase (eNOS) gene are strongly associated with several cardiovascular diseases (CVDs) in various populations. The current study aimed to investigate the association of the eNOS rs1800779 (A/G) polymorphism with the progress of myocardial infarction (MI). Methods Eighty-five he...

Nitric oxide, carbon monoxide and hydrogen sulfide are three endogenous gasotransmitters that serve a role in regulating normal and pathological cellular activities. They can stimulate or inhibit cancer cell proliferation and invasion, as well as interfere with cancer cell responses to drug treatments. Understanding the molecular pathways governing...

Extracellular vesicles (EVs) are small molecules produced by most cells that may aid in cell communication. They can transfer functional biomolecules from one cell to the next, and even across the body. Exosomes are some of the most studied extracellular vesicle components. Many medications may be incorporated into exosomes and then disseminated to...

Recently, there is increasing evidence that coronavirus disease 2019 (COVID-19) causes men to experience more serious symptoms and have a higher mortality rate than women, but the association between sex and immune response stays unknown till now, and weather patient’s prognosis associated with sex or not is another vague in COVID-19. In this study...

Background Multiple sclerosis (MS), as a neurodegenerative disorder, exhibits inflammation and oxidative stress hallmarks. Objective The research aims to know any disturbances in haematological parameters and antioxidant system of relapsing-remitting multiple sclerosis (RRMS) patients in the Kurdish population. Methods A case-control research mee...

Coronavirus disease-19 (COVID-19) is a complex disease that causes illness ranging from mild to severe respiratory problems. It is caused by a novel coronavirus SARS-CoV-2 (Severe acute respiratory syndrome coronavirus-2) that is an enveloped positive-sense single-stranded RNA (+ssRNA) virus belongs to coronavirus CoV family. It has a fast-spreadin...

Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders that are distinguished by the inability in social interaction, communication, and repetitive behavior pattern. One of the etiologic factors of the disease is believed to be methionine synthase reductase (MTRR) A66G polymorphism, which participates in homocysteine (Hcy)/folate...

Multiple sclerosis (MS) is a type of autoimmune disease where immune cell attacks our cells mistakenly; its severity is measured by expanded disease status scale (EDSS). The study aims the investigation of −1082 polymorphism in interleukin 10 (IL-10) as one of the etiologies that develops the disease. This is a case-control study that allele-specif...