Zheng Cheng

• srbg

Endophytic fungi play important roles in regulating plant growth and development and usually used as a promising strategy to enhance the biosynthesis of host valuable secondary metabolite, but the underlying growth-promoting mechanisms are only partly understood. In this study, the wild-type Arabidopsis thaliana seedlings co-cultured with fungal en...

[This corrects the article DOI: 10.1016/j.chmed.2020.07.002.].

Objective To establish multi-class bioactive constituents’ determination of ten Anoectochilus, four Goodyera and one Ludisia species, and provide reference for the improvement of their quality control. Methods HPLC-ELSD and phenol–sulphuric acid methods were used for the quantitative determination of lactone glycosides (kinsenoside and its diaster...

Searching for the p+ip superconducting (SC) state has become a fascinating subject in condensed matter physics recently, as a dream application awaiting in topological quantum computation. Unfortunately, so far there is no universal principle for realizing p+ip in generic solid-state systems. Here we report a theoretical discovery of a p+ip SC grou...

A wide range of external stress stimuli trigger plant cells to undergo complex network of reactions that ultimately lead to the synthesis and accumulation of secondary metabolites. Accumulation of such metabolites often occurs in plants subjected to stresses including various elicitors or signal molecules. Throughout evolution, endophytic fungi, an...

A new pterocarpan derivative, pruinosanone D (1), a new isoflavonoid, pruinosanone E (2), and a new chalcone, pruinosanone F (3), were isolated from Caragana pruinosa roots, along with four known analogues (4-7), identified as 2,4-dihydroxy-3'-methoxy-4'-ethoxychalcone, 7,4-dihydroxyflavanone, butin and scutellaprostin C, respectively. Their struct...

To investigate anti-arthritic effects of matrine isolated from the roots of S. flavescens on type II collagen-induced arthritis (CIA) in rats and to explore its related potential mechanisms, CIA rats were established and administered with matrine (20, 40 or 80 mg/kg/days, for 30 days). Subsequently, blood was collected to determine serum levels of...

The ground state phase of a spin-12 J1−J2 antiferromagnetic Heisenberg model on a square lattice around the maximally frustrated regime (J2∼0.5J1) has been debated for decades. Here we study this model using the cluster update algorithm for tensor-product states (TPSs). The ground state energies at finite sizes and in the thermodynamic limit (with...

Endophytic fungi or endophytes exist widely inside the healthy tissues of living plants, and are important components of plant micro-ecosystems. Over the long period of evolution, some co-existing endophytes and their host plants have established a special relationship with one and another, which can significantly influence the formation of metabol...

The genus Fagopyrum (Polygonaceae), currently comprising 15 species of plants, includes three important buckwheat species: Fagopyrum esculentum (F. esculentum) Moench. (common buckwheat), Fagopyrum tataricum (F. tataricum) (L.) Gaertn. (tartary buckwheat) and Fagopyrum dibotrys (F. dibotrys) (D. Don) Hara. (perennial buckwheat), which have been wel...

College young teachers are the reserve force and entrusted with the future development of the college and its disciplinary system. So it is very important to cultivate and enhance the quality of those young teachers in college. The first author is a growing young teacher in college. In term of the present situation and problems in college young tea...

We introduce a tensor renormalization group scheme for coarse-graining a two-dimensional tensor network that can be successfully applied to both classical and quantum systems on and off criticality. The key innovation in our scheme is to deform a 2D tensor network into small loops and then optimize the tensors on each loop. In this way, we remove s...

Background: Podocarpium podocarpum (DC.), an edible and medicinal plant popularly used for the treatment of bruises and fracture in Chinese folk medicine, has been proved to possess significant antiosteoporotic effect in our latest research. Purpose: Our study aimed to investigate the in vitro and in vivo antiosteoporotic effect of kaempfertrin...

Currently, human liver is susceptible to injury caused by alcohol and virus infiltration, resulting in hepatitis, cirrhosis, and even hepatocellular carcinoma. Paederia scandens (Lour.) Merr. var. tomentosa (Rubiaceae) has been used as traditional medicine in Asian countries to treat jaundice, dysentery, and abdominal mass. Furthermore, the abundan...

The string-net approach by Levin and Wen, and the local unitary transformation approach by Chen, Gu, and Wen, provide ways to classify topological orders with gappable edge in two-dimensional (2D) bosonic systems. The two approaches reveal that the mathematical framework for (2+1)-dimensional (2+1)D bosonic topological order with gappable edge is c...

Quantum-disordering a discrete-symmetry breaking state by condensing domain-walls can lead to a trivial symmetric insulator state. In this work, we show that if we bind a 1D representation of the symmetry (such as a charge) to the intersection point of several domain walls, condensing such modified domain-walls can lead to a non-trivial symmetry-pr...

It is well known that a bosonic Mott insulator can be realized by condensing vortices of a boson condensate. Usually, a vortex becomes an antivortex (and vice versa) under time reversal symmetry, and the condensation of vortices results in a trivial Mott insulator. However, if each vortex or antivortex interacts with a spin trapped at its core, the...

Our study aimed to investigate the antiosteoporotic properties of the ethanol extract of Podocarpium podocarpum (DC.) Yang et Huang (PE) in ovariectomized (OVX) rats and to characterize the active constituents. As a result, PE significantly inhibited the increased urinary Ca excretion and activity of bone resorption markers including tartrate-resis...

Our study aims to ascertain the antiinflammatory activity of Veronicastrum axillare and characterize the bioactive constituents. Antiinflammatory activity of the total extract and different fractions from V. axillare was investigated by employing the xylene-induced mouse ear edema model. As a result, the ethyl acetate (EtOAc) fraction showed the hi...

Rehmannia Libosch. ex Fisch. et C.A. Mey. is a small genus consisting of six species (R. glutinosa, R. chingii, R. elata, R. henryi, R. piasezkii, and R. solanifolia) in the Scrophulariaceae family, endemic to China [1]. R. glutinosa is the most popular one, the rhizome of which is known as “Dihuang” and is used for a variety disorders in tradition...

Abstract The development of plant tissue (including organ and cell) cultures for the production of secondary metabolites has been underway for more than three decades. Plant cell cultures with the production of high-value secondary metabolites are promising potential alternative sources for the production of pharmaceutical agents of industrial impo...

Ethnopharmacological relevance: Xanthium strumarium L. fruit (Xanthiu fruit) has been traditionally used as a medicinal herb in China for the treatment of many ailments including rheumatoid arthritis. However, the anti-arthritic activity of Xanthium strumarium fruit has still not been demonstrated. In the present study, we confirmed that the extra...

The seeds of Vitex negundo L (Verbenaceae) have been commonly used as a folk remedy for the treatment of rheumatism and joint inflammation in Traditional Chinese Medicine. This study aimed to evaluate the anti-arthritic activity of the extract of V. negundo seeds (EVNS) using Freund's complete adjuvant (CFA) induced arthritis (AA) in rat model. As...

3-(4-Fluorophenyl)-N-((4-fluorophenyl)sulphonyl)acrylamide (FFSA) is a potential tubulin polymerisation inhibitor. In this article, a theoretical study of the binding between FFSA and tubulin in colchicine site was carried out by molecular docking, molecular dynamics (MD) simulation and binding free energy calculations. The docking calculations pre...

The binding mode of (-)-zampanolide (ZMP) to tubulin was investigated using docking, molecular dynamics (MD) simulation, and binding free-energy calculations. The docking studies validated the experimental results indicating that the paclitaxel site is the binding site for (-)-ZMP. The 18 ns MD simulation shows the docking mode has changed a lot, w...

Chemical investigation of Vitex negundo seeds afforded four new lignans, including a phenylindene-type lignan, vitexdoin F (1), and three phenylnaphthalene-type lignans, vitexdoins G, H and I (2-4). Their structures were elucidated by detailed spectroscopic analyses on the basis of NMR, IR, and MS data. All compounds were evaluated for their anti-i...

To investigate the chemical constituents of the endophytic fungus Verticillium sp. isolated from Rehmannia glutinosa. The compounds were isolated and purified by repeated column chromatography, and their structures were determined on the basis of physicochemical properties and spectral analysis. Their cytotoxic and antifungal activities were evalua...

Abstract The molecular docking, MD simulation and binding free energy calculation were performed to explore the probable binding modes between PLA and tubulin. Through docking study, three possible binding sites for PLA were speculated as follows: the taxane site, the alternative site and a new site in α-tubulin. Then, 12.0 ns MD simulations show t...

To summarize the surgical technique and perioperative management of laparoscopic sleeve gastrectomy (LSG). A total of 57 morbid obesity patients undergoing LSG surgery from May 2010 to December 2012 were enrolled in the study, whose clinical data in perioperative period were analyzed retrospectively. These patients had more than 1 year of follow-up...

To evaluate the surgical outcomes and complications after laparoscopic adjustable gastric banding (LAGB) in obese patients. This retrospective study included 228 patients (73 males and 155 females, mean age, 32.5 ± 10.3 years) who underwent LAGB at the Changhai Hospital of the Second Military Medical University from June 2003 to June 2011. The body...

We construct a class of projected entangled pair states which is exactly the resonating valence bond wave functions endowed with both short range and long range valence bonds. With an energetically preferred resonating valence bond pattern, the wave function is simplified to live in a one-parameter variational space. We tune this variational parame...

Two strains of endophytic fungi, Penicillium melinii Yuan-25 and Penicillium janthinellum Yuan-27, with strong anti-Pyricularia oryzae activity, were obtained from the roots of Panax ginseng. Based on bioactivity-oriented isolation, a new benzaldehyde derivative, ginsenocin (1), together with six known compounds, methyl 2,4-dihydroxy-3,5,6-trimethy...

Introduction: Cervical cancer, the second most common gynecological malignant tumor seriously harmful to the health of women, remains a leading cause of cancer-related death for women in developing countries. Although a large amount of scientific research has been reported on plants as a natural source of treatment agents for cervical cancer, it i...

We study the effect of interactions on 2D fermionic symmetry-protected topological (SPT) phases using the recently proposed braiding statistics approach. We focus on a simple class of examples: superconductors with a Z2 Ising symmetry. Although these systems are classified by Z in the noninteracting limit, our results suggest that the classificatio...

To investigate the impacts of laparoscopic bariatric surgery on fasting glucagon-like peptide-1 (GLP-1) and Ghrelin level in patients with type 2 diabetes mellitus (T2DM), and the mechanism in surgical treatment of T2DM. From March 2010 to August 2011, 44 patients with T2DM underwent laparoscopic bariatric, including laparoscopic Roux-en-Y gastric...

Ethnopharmacological relevance: The dried root of Litsea cubeba (Lour.) Pers. (Family Lauraceae) has long been used as a folk remedy in Traditional Chinese Medicine (TCM) and Dai Ethnopharmacy for the treatment of rheumatic diseases in southwestern China. Aim of the study: This study investigated the preventive efficacy of Litsea cubeba root in...

Recently, two-dimensional band insulators with a topologically nontrivial (almost) flat band has been studied extensively, which can realize integer and fractional quantum Hall effect in a system without an orbital magnetic field. Realizing a topological flat band generally requires longer range hoppings in a lattice Hamiltonian. It is natural to a...

A novel bi-isoflavonoid, podocarnone (1), together with five known flavonoids, namely genistein (2), afzelin (3), astragalin (4), luteolin (5) and pratensein (6), were isolated from the whole plants of Podocarpium podocarpum (DC.) Yang and Huang for the first time. The structure of podocarnone (1) was elucidated by detailed spectroscopic analyses,...

We construct a class of projected entangled pair states (PEPS) which is exactly the resonating valence bond (RVB) wavefunctions endowed with both short range and long range valence bonds. With an energetically preferred RVB pattern, the wavefunction is simplified to live in a one parameter variational space. We tune this variational parameter to mi...

Seven new labdane-type diterpenoids, vitextrifolins A-G (1-7), along with eight previously reported analogues, were isolated from the fruits of Vitex trifolia. The structures of 1-7 were elucidated by spectroscopic data interpretation. The isolates were evaluated for their cytotoxicity against four human cancer cell lines (A549, HCT116, HL-60, and...

Comparative molecular field analysis (CoMFA) method was applied to study three-dimensional quantitative structure activity relationship (3D-QSAR) of a series of benzothiazole derivatives as potent anticancer agents. The CoMFA model of cross-validation and the partial-least-square (PLS) model of non cross-validation have been well established. The b...

Symmetry-protected topological (SPT) phases are bulk-gapped quantum phases with symmetries, which have gapless or degenerate boundary states as long as the symmetries are not broken. The SPT phases in free fermion systems, such as topological insulators, can be classified; however, it is not known what SPT phases exist in general interacting system...

Theoretical studies on the DNA-photocleavage efficiencies of Ru(ii) polypyridyl complexes have been carried out using density functional theory (DFT). First, an evaluation of the computational accuracy of the redox potentials for [Ru(bpy)(3)](2+) in the ground state and the excited state was tested by different computational methods. Secondly, the...

Objective: To investigate the outcomes after 2 methods of laparoscopic gastric bypass surgery for patients with type 2 diabetes mellitus(T2DM). Methods: From December 2009 to June 2011, 21 patients with T2DM underwent laparoscopic gastric bypass surgery, including laparoscopic Roux-en-Y gastric bypass (LRYGB, n=11), and laparoscopic mini-gastric...

An international symposium on the standard surgical treatment of morbid obesity and type 2 diabetes mellitus was held in Florida, USA in March 2011. An expert panel from all over the world attended the meeting. The expert panelists discussed and established International Sleeve Gastroectomy Expert Panel Consensus Statement : best practice guideline...

Six new acylphloroglucinol derivatives, sampsonols A-F (1-6), were isolated from the petroleum ether extract of the aerial parts of Hypericum sampsonii. The structures and relative configurations of sampsonols A-F were elucidated by extensive spectroscopic analyses. All these compounds were tested for their in vitro cytotoxic and anti-inflammatory...

Theoretical studies on the DNA-photocleavage efficiencies and mechanisms of Ru(II) complexes [Ru(bpy)2(L)]2+ (bpy = 2,2′-bipyridine; L: dppz = dipyrido[3,2-a:2′,3′-c]phenazine; mitatp = 5-methoxy-isatino[1,2-b]-1,4,8,9-tetraazatriphenylene; nitatp = 5-nitro-isatino [1,2-b]-1,4,8,9-tetraazatriphenylene) 1–3 were carried out using density functional...

Based on bioactivity-oriented isolation, the EtOAc extract of a culture broth of the endophytic fungus Perenniporia tephropora Z41 from Taxus chinensis var. mairei, with strong anti-Pyricularia oryzae activity, afforded a new sesquiterpenoid, perenniporin A (1), together with three known compounds, ergosterol (2), rel-(+)-(2aR,5R,5aR,8S,8aS,8bR)-de...

Vitex negundo Linn. (Verbenaceae) seeds are pepper substitute and occasionally used as a condiment for edible purposes. The seeds also find use for analgesia, sedation, rheumatism and joint inflammation in folk medicine. To isolate and characterize bioactive constituents from V. negundo seeds. The ethanol extract of V. negundo seeds was subjected t...

Inspired by the recent theoretical discovery of robust fractional topological phases without a magnetic field, we search for the non-abelian quantum Hall effect in lattice models with topological flat bands. Through extensive numerical studies on the Haldane model with three-body hard-core bosons loaded into a topological flat band, we find convinc...

We construct a 2D quantum spin model that realizes an Ising paramagnet with gapless edge modes protected by Ising symmetry. This model provides an example of a "symmetry-protected topological phase." We describe a simple physical construction that distinguishes this system from a conventional paramagnet: we couple the system to a Z_2 gauge field an...

We studied the spin 1/2 J1-J2 Heisenberg antiferromagnets on square lattice using the recently proposed cluster update for tensor network states [arXiv:1110.4362]. Ground state wavefunction with tensor network bond dimension upto D=9 was obtained. Through a finite size scaling analysis, we observe a second order phase transition from an antiferroma...

Theoretical studies on the related properties of Co(III) polypyridyl complexes [Co(phen)(2)L](3+) (L: dppz = dipyrido[3,2-a:2',3'-c]phenazine; phen = 1,10-phenanthroline; dione = 1,10-phenanthroline-5,6-diketone) 1-3 interacting with DNA, including the DNA-binding, DNA-photocleavage and spectral properties, have been carried out. First, the full ge...

Two new triterpenoid saponins, caraganins A and B (1 and 2), structurally characterized by a 22-oxo group, were isolated from the seeds of Caragana microphylla Lam., together with their n-butyl esters as artifacts (1a and 2a). Their structures and configurations were elucidated by detailed spectroscopic analyses on the basis of NMR, IR, and MS data...

Symmetry-protected topological (SPT) phases are gapped short-range-entangled quantum phases with a symmetry G, which can all be smoothly connected to the trivial product states if we break the symmetry. In this paper, we introduce a (special) group super-cohomology theory which is a generalization of the standard group cohomology theory. We show th...

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The ground state phase of spin-1/2 J_1-J_2 antiferromagnetic Heisenberg model on square lattice in the maximally frustrated regime (J_2 ~ 0.5J_1) has been debated for decades. Here we study this model by using a recently proposed novel numerical method - the cluster update algorithm for tensor product states (TPSs). The ground state energies at fin...

Inspired by recent theoretical discovery of robust fractional topological phases without a magnetic field, we search for the non-Abelian quantum Hall effect (NA-QHE) in lattice models with topological flat bands (TFBs). Through extensive numerical studies on the Haldane model with three-body hard-core bosons loaded into a TFB, we find convincing nu...

The emergence of superconductivity in doped Mott insulators has been debated for decades. In this paper, we report the theoretical discovery of a time-reversal symmetry breaking superconducting ground state in the doped Mott insulator (described by the well known t-J model) on honeycomb lattice, based on a recently developed variational method: the...

Recent proposals of topological flat band models have provided a new route to realize the fractional quantum Hall effect without Landau levels. We study hard-core bosons with short-range interactions in two representative topological flat band models, one of which is the well-known Haldane model (but with different parameters). We demonstrate that...

Chemical investigation on the seeds of Vitex negundo has afforded a new furan-containing sesquiterpenoid, negunfurol (1), a new norlabdane-type diterpenoid, negundoal (2), and two new norursane-type triterpenoids, negundonorins A (3) and B (4), together with two know compounds, 3-formyl-4,5-dimethyl-8-oxo-5H-6,7-dihydronaphtho[2,3-b]furan (5) and 3...

The hydrolysis process of Ru(III) complex (HL)[trans-RuCl4L(dmso-S)] (L=1-methyl-1,2,4-triazole and dmso-S=S-dimethyl sulfoxide) (1), a potential antitumor complex similar to the well-known antitumor agent (Him)[trans-RuCl4(dmso-S)(im)] (NAMI-A, im=imidazole), was investigated using density functional theory combined with the conductor-like polariz...

A new furanofuran lignan, vitelignin A (1), together with eight known lignan derivatives, were isolated from the seeds of Vitex negundo. Their structures were identified as (+)-4-oxo-8-hydroxy-2,6-di(3,4-methylenedioxy)phenyl-3,7-dioxabicyclo[3.3.0]octane (1), 4-oxosesamin (2), (+)-sesamin (3), (+)-paulownin (4), 4-hydroxysesamin (5), 4,8-dihydroxy...

It is well known that the topological phenomena with fractional excitations, the fractional quantum Hall effect, will emerge when electrons move in Landau levels. Here we show the theoretical discovery of the fractional quantum Hall effect in the absence of Landau levels in an interacting fermion model. The non-interacting part of our Hamiltonian i...

Two new sesquiterpenoids, identified as (rel 1S, 3R, 4R, 7R)-3-[5-hydroxy-4-methylpent-3-enyl]-1, 3, 7-trimethyl-2-oxabicyclo [2, 2, 1] heptane (1) and (rel 1S, 3R, 4R, 7R)-3-[3, 4-dihydroxy-4-methylpentyl]-1, 3, 7-trimethyl-2-oxabicyclo [2, 2, 1] heptane (2), were isolated from cultures of Trichoderma atroviride (strain no. S361), an endophytic fu...

Crocus sativus Linn. (Iridaceae), commonly known as saffron, becomes more and more popular due to its versatile biological and medicinal properties. At present, studies mainly focus on the traditional medicinal part, the saffron stigma, with less attention to the other parts of saffron, such as the perianth, the stamen, and the corm, which are high...

Symmetry protected topological (SPT) phases are gapped short-range-entangled quantum phases with a symmetry G. They can all be smoothly connected to the same trivial product state if we break the symmetry. The Haldane phase of spin-1 chain is the first example of SPT phase which is protected by SO(3) spin rotation symmetry. The topological insulato...

The crude extract of Acanthopanax senticosus (AS) has been used extensively in Russia, China, Korea and Japan as an adaptogenic agent to fight against stress and fatigue. However, whether the liposoluble fraction possesses antifatigue activity or not is still unclear. A liposoluble fraction was administered orally to mice for 9 days. The swimming t...

Two new triterpenoid saponins, namely caraganoside C (1) and caraganoside D (2), were isolated from the seeds of Caragana microphylla. Their structures were elucidated on the basis of spectroscopic analyses, including homo- and hetero-nuclear correlation NMR experiments (COSY, HSQC and HMBC). Both 1 and 2 exhibited moderate inhibitory activity agai...

Endophytic fungi are microorganisms living within the tissues of host plants, and have proven to be rich sources of biologically active secondary metabolites and therefore have attracted increasing attention in recent years. To isolate and characterize bioactive constituents from the endophytic fungus cultures of Crocus sativus Linn. (Iridaceae). E...

Trichodermanin A, a structurally unique diterpenoid with skeletal carbons arranged compactly in a fused 6-5-6-6 ring system, has been isolated from cultures of Trichoderma atroviride (strain no. S361), an endophytic fungus isolate in Cephalotaxus fortunei. The structure of this compound was elucidated based on extensive spectroscopic methods and co...

Quantum phases with different orders exist with or without breaking the symmetry of the system. Recently, a classification of gapped quantum phases which do not break time reversal, parity or on-site unitary symmetry has been given for 1D spin systems in [X. Chen, Z.-C. Gu, and X.-G. Wen, Phys. Rev. B \textbf{83}, 035107 (2011); arXiv:1008.3745]. I...

Recent proposals of topological flat band (TFB) models have provided a new route to realize the fractional quantum Hall effect (FQHE) without Landau levels. We study hard-core bosons with short-range interactions in two representative TFB models, one of which is the well known Haldane model (but with different parameters). We demonstrate that FQHE...

Topological phases exist in quantum many-body systems beyond the usual symmetry breaking understanding of phase and phase transition. While a full classification of topological insulators and superconductors has been given for non-interacting fermions, the question of what phases exist for strongly interacting systems and how to identify them seems...

Motivated by the recent proposal of a Mott insulating state with strong spin-orbit coupling for the Iridate Na2IrO3[1], we discuss the collective ground states of the effective Iridium moments in the presence of Heisenberg-Kitaev exchange interactions and a time-reversal symmetry breaking magnetic field. For a field pointing in the (111) direction...

Desmodium podocarpum is a plant that has been used in the folk medicine to treat febrile diseases, cough and bleeding wounds. However, there is no scientific basis or reports in the modern literature regarding its effectiveness as an analgesic, anti-inflammatory and antipyretic agent. The objective of this study is to evaluate the analgesic, anti-i...

To evaluate the outcomes after laparoscopic gastrointestinal surgery for patients with obesity and type 2 diabetes mellitus(T2DM). From June 2003 to June 2010, 219 patients underwent laparoscopic gastrointestinal surgery for obesity and T2DM, including laparoscopic adjustable gastric banding(LAGB, n=201), laparoscopic mini gastric bypass(LMGB, n=13...

Quantum many-body systems divide into a variety of phases with very different physical properties. The questions of what kinds of phases exist and how to identify them seem hard, especially for strongly interacting systems. Here we make an attempt to answer these questions for gapped interacting quantum spin systems whose ground states are short-ra...

Motivated by the recent experimental observation of a Mott insulating state for the layered Iridate Na2IrO3, we discuss possible ordering states of the effective Iridium moments in the presence of strong spin-orbit coupling and a magnetic field. For a field pointing in the [111] direction - perpendicular to the hexagonal lattice formed by the Iridi...

Symmetry protected topological (SPT) phases are gapped short-range-entangled quantum phases with a symmetry $G$, which can all be smoothly connected to the same trivial product state if we break the symmetry. In this paper, we propose that distinct $d$-dimensional bosonic SPT phases with on-site symmetry $G$ (which may contain anti-unitary time rev...

A theoretical study was conducted on the effects of three substituents in the Ru(II) polypyridyl complex, [Ru(phen)2(6-R-dppz)]2+, (R = H for complex 1, OH for complex 2, and NO2 for complex 3), on the photocleavage of DNA. The geometric and electronic structures of these complexes in the ground (S0), first singlet (S1), and triplet (T1) excited st...

A new dibenzocyclooctane lignan, schisanbicolorin A, together with fifteen known lignans, were isolated from the stems of Schisandra bicolor Cheng. Their structures were identified as (aS,6R,7S)-5,6,7,8-tetrahydro-2,3,13-trimethoxy-6,7-dimethyldibenzo[3,4]cycloocta [1,2-f][1,3]benzodioxol-1-ol (1), neglschisandrin C (2), angeloylgomisin R (3), schi...

To investigate the effects of Gastric bypass surgery on the apoptosis of islet β-cells in type 2 nonobese diabetic (NOD) rats and its mechanisms. Seventy-two 8-week-old GK rats were randomly divided into four groups:operation group (group O, n = 18), sham operation group (group S, n = 18), diet control group (group F, n = 18) and control group (gro...

to investigate the anti-hyperprolactinemia activity of casticin, a flavonoid isolated from Vitex rotundifolia, and elucidate its molecular mechanism. hyperprolactinemia (MIHP) was induced by administration of metoclopramide dihydrochloride (50 mg/kg, tid, ip, for 10 d) in SD rats and the primary pituitary cells were prepared from the pituitary glan...

The string-net approach by Levin and Wen, and the local unitary transformation approach by Chen, Gu, and Wen, provide ways to systematically describe topological orders in 2D boson systems. The two approaches reveal that the mathematical framework for topological order is closely related to (projective) tensor category theory. In this paper, we gen...

Theoretical studies on the spectral and DNA-photocleavage properties of Co(III) and Ru(II) polypyridyl complexes [M(phen)2(pyip)]n+ (M = Co(III) and Ru(II), n = 3 and 2, respectively) have been carried out, using DFT, HF and CIS methods. The electronic absorption spectra of the two complexes were calculated and simulated using TDDFT and CPCM model....

Quantum many-body systems divide into a variety of phases with very different physical properties. The question of what kind of phases exist and how to identify them seems hard especially for strongly interacting systems. Here we make an attempt to answer this question for gapped interacting quantum spin systems whose ground states are short-range...

The antinociceptive activities of the petroleum ether fraction (PEF) from the aqueous ethanol extract of Vitex negundo Linn. (Verbenaceae) seeds have been evaluated in several nociceptive mouse models. Given orally, the PEF (at doses of 12, 24, and 48 mg/kg body weight) produced significant dose-related inhibitions on chemical nociception induced b...

Two gapped quantum ground states in the same phase are connected by an adiabatic evolution which gives rise to a local unitary transformation that maps between the states. On the other hand, gapped ground states remain within the same phase under local unitary transformations. Therefore, local unitary transformations define an equivalence relation...

The projective construction (the slave-particle approach) has played an very important role in understanding strongly correlated systems, such as the emergence of fermions, anyons, and gauge theory in quantum spin liquids and quantum Hall states. Recently, fermionic Projected Entangled Pair States (fPEPS) have been introduced to effciently represen...

The tensor product representation of quantum states leads to a promising variational approach to study quantum phase and quantum phase transitions, especially topological ordered phases which are impossible to handle with conventional methods due to their long range entanglement. However, an important issue arises when we use tensor product states...

Laparoscopic resection of gastric stromal tumors is being performed with increased frequency. This study aims to evaluate the feasibility and safety of the extraluminal laparoscopic gastric wedge resection (ELWR) technique. Clinical data of 84 patients who underwent ELWR for gastric submucosal tumors between September 2000 and December 2007 were re...

To report the newly developed reconstruction technique after laparoscopic total gastrectomy: intracorporeal circular stapling esophagojejunostomy using the transorally inserted anvil (OrVil; Covidien), and evaluate its feasibility, safety, and clinical outcomes. After LTG (3 patients with gastric carcinoma in the body) or LPG (2 patients with gastr...