Zhen Xuen Brandon Low

• Student at Monash University Malaysia

Rationale In our ongoing battle against the coronavirus 2019 (COVID-19) pandemic, a major challenge is the enduring symptoms that continue after acute infection. Also known as Long COVID, post-COVID-19 syndrome (PCS) often comes with debilitating symptoms like fatigue, disordered sleep, olfactory dysfunction, and cognitive issues (“brain fog”). Cur...

In vertebrates, the circadian mechanism regulates many physiological and behavioral activities. The major key output of the circadian clock is the secretion of melatonin in the pineal gland. Melatonin secretion remains low during the daytime and increases significantly at night. The rise and fall of melatonin level is a key factor that conveys rhyt...

Emerging evidence suggests that classical psychedelics possess immunomodulatory and anti-inflammatory properties; however, these effects are yet to be well-established. This systematic review aims to provide a timely and comprehensive overview of the immunomodulatory effects of classical psychedelics in preclinical studies. A systematic search was...

Sleep is an essential biological phase of our daily life cycle and is necessary for maintaining homeostasis, alertness, metabolism, cognition, and other key functions across the animal kingdom. Dysfunctional sleep leads to deleterious effects on health, mood, and cognition, including memory deficits and an increased risk of diabetes, stroke, and ne...