Zhaowei Kong

• PhD
• Professor (Associate) at University of Macau

Intermittent normobaric hypoxia training, an alternative to altitude training for athletes, may be beneficial to treat overweight and obesity. The purpose of this study is to investigate whether normobaric hypoxia training combined with low-caloric diet has the additive effect on weight loss compared with normoxia training in obese young adults. Tw...

Objective: The aim of this study was to compare the effects of 5-week high-intensity interval training (HIIT) and moderate-to-vigorous intensity continuous training (MVCT) on cardiometabolic health outcomes and enjoyment of exercise in obese young women. Methods: A randomized controlled experiment was conducted that involved thirty-one obese fem...

This study aimed to examine the effects of four weeks of a low-carbohydrate diet (LC) and incorporated exercise training on body composition and cardiometabolic health. Fifty-eight overweight/obese Chinese females (age: 21.2 ± 3.3 years, body mass index (BMI): 25.1 ± 2.8 kg/m 2) were randomly assigned to the control group (CON, n = 15), the LC cont...

Background The efficacy of exercise interventions in the treatment of mental health disorders is well known, but research is lacking on the most efficient exercise type for specific mental health disorders. Objective The present study aimed to compare and rank the effectiveness of various exercise types in the treatment of mental health disorders....

Interval training protocols have gained popularity over the years, but their impact on appetite sensation compared to officially recommended training method, moderate intensity continuous training (MICT) is not well understood. Thus, this systematic review and meta-analysis aimed to compare a single session of high intensity interval training (HIIT...

Background: Insufficient physical activity and prolonged sedentary behavior have emerged as major global public health challenges. Short bouts (≤10 min) of accumulated exercise (SBAE) throughout the day may be a promising strategy to mitigate the adverse effects of prolonged sitting and promote physical activity, ultimately promoting overall health...

This study explored the impact of circadian rhythms on the circulating cardiac troponin T (cTnT) response to a graded exercise test (GXT) and examined whether an initial GXT influenced the cTnT response to a subsequent GXT performed 7–9 days later. Twenty‐one healthy young males (age: 20.6 ± 2.2 years, body mass index: 22.2 ± 2.6 kg/m², V̇O2max: 31...

Background This study evaluated physical fitness and mental health in young and elderly women 3 months after mild COVID-19 infection, and examined the impact of infection and age on long COVID occurrence and trajectory. Methods There were 213 eligible female volunteers (107 young, 106 elderly) recruited approximately three months after the signifi...

Background: The impact of COVID-19 infection on physical and mental health of young adults remains unclear. This study aimed to investigate the changes in the physical fitness three months after recovering from acute COVID-19 infection, and examine if the infection could also influence the mental health of university students. Methods: A total of 4...

This study investigated the acute effects of ketone monoester on metabolic and neurocognitive indicators and underlying metabolism-brain-cognition interactions among young adults of healthy weight (HW) and those with overweight/obesity (OW). Forty participants were divided into two groups: HW (n = 20, age 23.80 ± 3.96 years, body mass index (BMI) 2...

Repeated-sprint training in hypoxia (RSH) has been shown to boost team-sport players' repeated-sprint ability (RSA). Whether players' global inspiratory muscle (IM) and core muscle (CM) functions would be altered concomitantly with RSH was not reported. This study was designed to compare the concomitant alternations in players' RSA and their IM and...

Objectives To transform the standardized descriptions of the ultrasound characteristics of endometrial and intrauterine lesions devised by the International Endometrial Tumor Analysis (IETA) group into a practical scoring method and to investigate whether application of this method enhances the diagnostic accuracy of ultrasound radiologists with di...

There is evidence that complex relationships exist between motor functions, brain structure, and cognitive functions, particularly in the aging population. However, whether such relationships observed in older adults could extend to young adults remains to be elucidated. Thus, the current study addressed this gap in the literature by investigating...

Transcranial direct current stimulation (tDCS) and high-intensity interval training (HIIT) have been demonstrated to enhance inhibitory control and working memory (WM) performance in healthy adults. However, the potential benefits of combining these two interventions have been rarely explored and remain largely speculative. This study aimed to expl...

Ratio-scaled VO2 is the widely used method for quantifying running economy (RE). However, this method should be criticized due to its theoretical defect and curvilinear relationship indicated by the allometric scaling, although no consensus has been achieved on the generally accepted exponent b value of body weight. Therefore, this study aimed to p...

Background Enhancement in maximal oxygen consumption (VO2max) induced by hypoxic training is important for both athletes and non-athletes. However, the lack of comparison of multiple paradigms and the exploration of related modulating factors leads to the inability to recommend the optimal regimen in different situations. This study aimed to invest...

Purpose To investigate (1) the boosting effects immediately and 4 weeks following 2-week, 6-session repeated-sprint training in hypoxia (RSH2-wk, n = 10) on the ability of team-sport players in performing repeated sprints (RSA) during a team-sport-specific intermittent exercise protocol (RSAIEP) by comparing with normoxic counterpart (CON2-wk, n =...

Background: Effects of ketone supplements as well as relevant dose-response relationships and time effects on blood β-hydroxybutyrate (BHB), glucose and insulin are controversial. Objective: This study aimed to summarize the existing evidence and synthesize the results, and demonstrate underlying dose-response relationships as well as sustained...

Background: Exercise intensity has been suggested to influence acute appetite-regulating gut hormone responses after exercise. High intensity interval training (HIIT) with near maximal to maximal intensity or sprint interval training (SIT) with supramaximal intensity might induce greater effects on gut hormones compared to moderate intensity conti...

It is unclear whether virtual reality (VR)-based exercise can improve physical fitness in people with intellectual disability (ID). This systematic review therefore aimed to synthesize existing evidence regarding the efficacy of VR-based exercise on physical fitness in people with ID. Eligible articles were searched through six major electronic dat...

In this study we investigated changes in concentrations of cerebral oxyhaemoglobin (O2Hb), deoxyhaemoglobin (HHb), and total haemoglobin (tHb) during repeated sprints and their relationship with cardiac output. We also examined the effect of glucose ingestion and acute hyperglycaemia on cerebral haemoglobin responses. Ten young male participants in...

Simple Summary Transcranial direct current stimulation (tDCS) is used as an adjuvant rehabilitation treatment to improve postural control and lower limb function. This study explored the effects of sham and anodal tDCS over the leg region of M1 on static and dynamic postural stability in healthy young adults. Jump-landing tasks were used to examine...

This study examined the alterations of heart rate variability (HRV) following iso-duration resistance (RES) and sprint-interval exercises (SIE) by comparing with that of non-exercise control (CON) in 14 non-obese (NOB) and 15 obese (OB) young men. Time and frequency domain measures as well as nonlinear metrics of HRV were assessed before and immedi...

Objective: The aim of our study was to examine cognition response to sprint interval exercise (SIE) against different levels of hypoxia. Research design and methods: 26 recreational active males performed SIE (20 × 6 s of all-out cycling bouts, 15 s of passive recovery) under normoxia (FIO2: 0.209), moderate hypoxia (FIO2: 0.154), and severe hyp...

Kong, Zhaowei, Qian Yu, Shengyan Sun, On Kei Lei, Yu Tian, Qingde Shi, Jinlei Nie, and Martin Burtscher. The impact of sprint interval exercise in acute severe hypoxia on executive function. High Alt Med Biol. xx:xxx-xxx, 2022. Objective: The present study evaluated executive performance responses to sprint interval exercise in normoxia and relativ...

Objective This study was aimed to evaluate the effects of low-carbohydrate diet (LC) and incorporated high-intensity interval training (HIIT) or moderate-intensity continuous training (MICT) on gut microbiota, and the associations between changes in gut microbiota and cardiometabolic health-related profiles. Methods Fifty overweight/obese Chinese...

Background The purpose of this study was to compare the differences in enjoyment and affect in response to four weight control intervention protocols over 12 weeks. Methods Sixty overweight young females were randomised into four intervention groups: repeated sprint training (RST, 6-sec all-out sprint interspersed with 9-sec rest), high-intensity...

Sprint interval training (SIT) is characterized by intensity of “all-out” effort and superior time-efficiency compared to traditional moderate-intensity continuous training (MICT) and has been proposed as one viable solution to address the commonly reported barrier of lack of time for physical activity. While substantial physiological benefits of p...

Background Studies have shown that high-intensity interval training (HIIT) is superior to moderate-intensity continuous training (MICT) for increasing peak oxygen uptake (VO 2peak ) and reducing cardiovascular disease (CVD) and mortality. To our knowledge, previously published systematic reviews have neither compared different HIIT models with MICT...

This study aims to examine relations between Chinese preschoolers’ physical well-being (physical fitness and motor skills), executive functioning, and academic skills (receptive language, math, and science skills) at the end of the Kindergarten year, the last year of preschool in the Chinese early childhood education system. A total of 273 children...

Background and objective Episodic memory enables people to recall and re-experience episodes associated with past spatial and temporal context. This study examined the effect of physical exercise break during prolonged sitting on episodic memory performance. Further, we investigated functional connectivity as a possible mechanisms contributing to e...

Objective The purpose of this study was to investigate the effects of repeated sprint interval training (RSIT) under different hypoxic conditions in comparison with normoxic RST on cardiorespiratory fitness (CRF) and metabolic health in sedentary young women. Methods Sixty-two sedentary young women (age 21.9 ± 2.8 years, peak oxygen uptake [V̇O2pe...

The purpose of this study was to determine whether exercise training mediated cardiac troponin T (cTnT) and whether this was associated with increases in left ventricular mass (LVM). Fifty-four sedentary obese women were randomised to high-intensity interval training (HIIT, repeated 4-min cycling at 90% V̇O2max interspersed with 3-min rest), work-e...

The present study aimed to determine the effect of wearing a face mask during aerobic dance exercise on cognitive function, more specifically on attention, as well as on perceived exertion and mood states. Thirteen healthy college students (9 males and 4 females: mean age = 17.5 years, height = 1.72 m, weight = 71.00 kg) volunteered to participate...

Background: It remains uncertain whether exercise modality (high-intensity interval [HIE]; moderate-intensity continuous [MCE]) mediates exercise-induced changes in markers of pro-arrhythmogenic state and/or cardiac damage. This study examines heart rate variability (HRV) and cardiac troponin T (cTnT) kinetic responses to HIE and MCE. Methods: Fou...

Objectives This study examined the influences of the volume of all-out sprint-interval exercise (SIE) on acute post-exercise heart rate variability (HRV) recovery. Methods HRV recovery following a session of (i) 2 × 30-s SIE (SIE2), (ii) 4 × 30-s SIE (SIE4), and (iii) non-exercising control (CON) were compared in 15 untrained young males. Time dom...

The present study aimed to investigate the effect of transcranial alternating current stimulation (tACS) on the primary motor cortex (M1) during action observation, and subsequent action execution, on motor cortex excitability. The participants received tACS at 10 Hz or 20 Hz, or a sham stimulation over the left M1 for 10 min while they observed a...

Benefits of performing sprint interval training (SIT) under hypoxic conditions on improving cardiorespiratory fitness and body composition have been well-documented, yet data is still lacking regarding affective responses to SIT under hypoxia. This study aimed to compare affective responses to SIT exercise under different oxygen conditions. Ninetee...

Objective: The purpose of this study was to evaluate the effects of a 4-week low-carbohydrate diet (LC) with or without exercise training on cardiometabolic health-related profiles in overweight/obese women. Methods: Fifty overweight/obese Chinese women (age: 22.2 ± 3.3 years, body mass index (BMI): 25.1 ± 3.1 kg·m-2) were randomized to either a...

Objectives: the current study aimed to investigate the relationship between physical activity (PA) level and inhibitory control performance and then to determine whether this association was mediated by multiple sleep parameters (i.e., subjective sleep quality, sleep duration, sleep efficiency, and sleep disturbance). Methods: 180 healthy universit...

The present research examined the effects of family-related factors on how parents perceive and choose physical activities that stimulate their children’s physical fitness and motor development. Using the random sampling approach, a total of 284 4- to 5-year-old children (n = 147 boys; n = 137 girls) were included in the sample. These children’s ph...

The current study aimed to investigate the relationship between physical activity (PA) level and inhibitory control performance and then determine whether this association was mediated by multiple sleep parameters (i.e., subjective sleep quality, sleep duration, sleep efficiency, sleep disturbance). Methods. 180 healthy university students (age: 20...

Cardiorespiratory fitness (CRF) is assumed to exert beneficial effects on brain structure and executive control (EC) performance. However, empirical evidence of exercise-induced cognitive enhancement is not conclusive, and the role of CRF in younger adults is not fully understood. Here, we conducted a study in which healthy young adults took part i...

This study examined the effects of 12 weeks of sprint interval training (SIT), high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on cardiorespiratory fitness (peak oxygen uptake, VO 2peak), body composition and physical activity enjoyment in overweight young women. Sixty-six participants (age 21.2 ± 1.4 years...

Background: It has been shown that prolonged exhaustive exercise, such as half-marathon running, could lead to transient post-exercise elevation of cardiac troponins, increase in oxidative stress, and mild decline in renal function in adolescent athletes. With increases in sports participation involving young people, there has been much interest i...

Problematic smartphone use (PSU) has become a prevalent issue worldwide. Previous studies suggest that physical exercising may effectively reduce smartphone users’ addiction levels. Comparisons and further evaluations on the long-term effects of different types of exercise-based interventions on treating PSU remain to be investigated. Objective. We...

Background/Objective Mental health problems are common among adolescents and greatly influenced by stressful events. This study sought to assess the prevalence and correlates of insomnia, depressive and anxiety symptoms among Chinese adolescents during the COVID-19. Method Cross-sectional study (N = 1794 adolescents, mean age = 15.26) was conducte...

Background: Physical exercises can affect executive function both acutely and chronically, with different mechanisms for each moment. Currently, only a few reviews have elaborated on the premise that different types of exercises have different mechanisms for improving executive function. Therefore, the primary purpose of our systematic review was t...

Objective: The current study aimed at comparing the effects of Tai Chi (a motor-cognitive exercise) with walking (an exercise without cognitive demands) on cognitive performance, brain structure, and brain function in the elderly. Methods: This cross-sectional study included 42 healthy elderly women within two groups: Tai Chi (n = 20; mean age =...

Visceral fat loss in response to four-cycle ergometer training regimens with explicit differences in exercise intensity and modality was compared. Fifty-nine obese young women (body fat percentage ≥ 30%) were randomized to a 12-week intervention consisting of either all-out sprint interval training (SITall-out , n = 11); supramaximal SIT (SIT120 ,...

The purpose of this study was to examine the effects of a short-term ketogenic diet (KD) on body composition and cardiorespiratory fitness (CRF) in overweight/obese Chinese females. Twenty young females [age: 21.0 ± 3.7 years, weight: 65.5 ± 7.7 kg, body mass index (BMI): 24.9 ± 2.7 kg⋅m–2] consumed 4 weeks of a normal diet (ND) as a baseline and t...

Objective The current study aimed at determining effects of Tai Chi as an example of a combined motor-cognitive exercise relative to regular walking as an example of an exercise without cognitive demands on cognitive functioning and the functional and structural integrity of the brain in the elderly. Methods Healthy elderly women with at least 6 y...

The impairment of cognitive function can cause substantial emotional and financial burdens. A recent global increasing trends in cognitive impairment and associated disorders have been observed, which will continue to grow coupled with the rapidly aging population. As a non-pharmaceutical approach, calorie restriction has received wide research int...

Purpose This study aimed to examine (1) the independent effects of hypoxia on cognitive function and (2) the effects of exercise on cognition while under hypoxia. Methods Design: Systematic review with meta-analysis. Data sources: PubMed, Scopus, Web of Science, PsychInfo, and SPORTDiscus were searched. Eligibility Criteria for Selecting Studies:...

Low-carbohydrate diets (LCs) seem effective on weight reduction and maintenance. However, the affect and enjoyment of exercise during LCs is not clear. The purpose of the present study was to compare the psychological responses to high-intensity interval training (HIIT) and to moderate-intensity continuous training (MICT) during the consumption of...

Background: Skeletal muscle atrophy induced by hypoxia could affect the physical fitness and training effect of the athletes in the rapid altitude, and also affect the production and life of the general public. Resistance training in a hypoxic environment could effectively alleviate the occurrence of muscular atrophy. Whether autophagy lysosomal pa...

Purpose: Previous research has evaluated the effects of acute hypoxia exposure on cognitive function, notably executive function. No studies, to date, have evaluated the effects of acute hypoxia exposure on memory interference, which was the purpose of this experiment. Methods: A within-subjects, counterbalanced experimental design was employed, wi...

Objectives: It is unclear whether exercise modality (moderate-intensity continuous [MCE]; high-intensity interval [HIE]) and menstrual cycle phase (follicular [FP]; luteal [LP]), individually or in combination, mediate the commonly observed exercise-induced elevation in cardiac troponin T (cTnT). This study examines cTnT responses to MCE and HIE d...

This study examined the effects of a specific core exercise program, as a re-warm-up regime during the half-time period, on inspiratory (IM) and core (CM) muscle functions, leg perfusion and the team sport-specific sprint performance in the initial stage of the second half of a simulated exercise task. Nine team-sports players performed a simulated...

Background: Cognitive decline and balance impairment are prevalent in the aging population. Previous studies investigated the beneficial effects of 24-style Tai Chi (TC-24) on either cognitive function or balance performance of older adults. It still remains largely unknown whether modified Chen-style TC (MTC) that includes 18 complex movements is...

Aims: To compare postprandial glucose responses to high-intensity interval exercise (HIE) between obese and lean individuals. Methods: Thirty healthy young adult males (15 obese, 15 lean) ate a standardised meal, then performed HIE (4 × 30-s Wingate cycling/4-min rest) or a no-exercise control trial (CON). Blood glucose was measured preprandially a...

The risk of malignant arrhythmias is higher during extremely intense exercise and after its cessation. It is still unclear whether high-intensity interval exercise (HIE), an increasingly popular option in preventive and rehabilitative medicine, can lead to an impaired electrophysiological milieu, as revealed by QT interval prolongation on an electr...

Purpose Exercise induces a cardioprotective effect referred to as “preconditioning”. Whether the preconditioning impacts upon the cardiac troponin T (cTnT) response to subsequent exercise bouts is unclear. This study investigated the effects of an initial exercise bout, a second exercise bout 48 h later, as well as subsequent exercise every 48 h fo...

Objective: The purpose of this study was to investigate the effects of Tai Chi (TC) on anthropometric parameters and physical fitness among children and adolescents with intellectual disabilities (ID). Methods: Sixty-six Chinese individuals engaged in sport-related extracurricular activities (TC and aerobic exercise (AE)) as exercise interventio...

Purpose:To examine the effect of acute moderate-intensity continuous exercise performedunder normobaric severe hypoxia on cognition, compared to sea-level normoxia.Methods:Thirtyhealthy inactive women randomly performed two experimental trials separated by at least three daysbut at approximately the same time of day. Executive functions were measur...

This current meta-analysis review was conducted to examine the effectiveness of Qigong-based therapy on individuals with major depressive disorder. Six electronic databases (PubMed, PsycINFO, Cochrane Library, and Web of Science, Chinese National Knowledge Infrastructure, and Wangfang) were employed to retrieve potential articles that were randomiz...

Objective: The purpose of this study was to investigate the effects of Tai Chi (TC) on arterial stiffness, physical function of lower-limb, and cognitive ability in adults aged over 60. Methods: This study was a prospective and randomized 12-week intervention trial with three repeated measurements (baseline, 6, and 12 weeks). Sixty healthy adults w...

Some studies have shown that resistance training combined with plyometric training is more time-efficient and effective for fitness development. The degree and frequency of combined training might influence the benefit of training to maintain time. To better understand this phenomenon of the degree and frequency of combined training in pre- and ear...

Tai Chi (TC) can be considered safe and effective intervention to improve pain and pain-related functional disability. However, it is unclear that whether aging individuals with Chronic Non-Specific Low Back Pain (CNS-LBP) can achieve positive results. This study, therefore, attempted to explore the effects of TC on pain and functional disability i...

Background and Objectives: Limited research has evaluated the effects of acute exercise on cognition under different conditions of inspired oxygenation. Thus, the purpose of this study was to examine the effects of high-intensity interval exercise (HIE) under normoxia (inspired fraction of oxygen (FIO2): 0.209) and moderate hypoxia (FIO2: 0.154) on...

Objective: This study is the first meta-analysis investigating the rehabilitative effects of Wuqinxi for patients with chronic obstructive pulmonary disease (COPD). Methods: Five electronic databases (PubMed, Web of Science, Scopus, CNKI, and Wanfang) from inception until early November 2018 were searched. All randomized controlled trials (RCT) usi...

Aims This study characterized (1) the cardiac troponin T (cTnT) response to three forms of acute high‐intensity interval exercise (HIE), and (2) the impact of 12 weeks of HIE training on the cTnT response to acute exercise in sedentary obese young women. Methods Thirty‐six sedentary women were randomized to traditional HIE training (repeated 4‐min...

This study compared the effects of 12-week sprint interval training (SIT), high-intensity interval training (HIIT), and moderate-intensity continuous training (MICT) on cardiorespiratory fitness (V̇O2peak), body mass and insulin sensitivity in overweight females. Forty-two overweight women (age 21.2 ± 1.4 years, BMI 26.3 ± 2.5 kg·m⁻²) were randomiz...

Introduction: High-intensity interval training (HIIT) is an emerging lifestyle intervention strategy for controlling obesity. HIIT consisted of brief all-out supramaximal sprint intervals was termed as sprint interval training (SIT). This study was designed to examine the time-efficient characteristics of SIT in reducing abdominal visceral fat. Met...

Background/Objective This study examined whether time spent at high rates of oxygen consumption (VO2) during 6-s sprint interval exercises (SIE) is a function of recovery interval duration. Methods In a randomised crossover study, thirteen male endurance runners performed 40 × 6-s all-out sprints interspersed with 15-s, 30-s and 60-s passive recov...

New findings: What is the central question of this study? Does exercise training impact resting and postexercise cardiac troponin T (cTnT) concentration? What is the main finding and its importance? This randomized controlled intervention study demonstrated that 12 weeks of either high-intensity interval training or moderate-intensity continuous t...

Previous studies have investigated the effects of high-intensity interval training (HIIT) on cardiorespiratory fitness and body composition in overweight populations. However, the additive effect of HIIT and hypoxia on health parameters is not clear. This study compared the effects of HIIT under hypoxic conditions on cardiometabolic function with t...