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Publications (58)
Performance validity tests (PVTs) can be seen as gatekeepers for valid neuropsychological assessment, by marking cognitive test scores that may not reflect true ability levels. The present study explored the significance of repeated validity testing of adults with attention-deficit/hyperactivity disorder (ADHD), by exploring the potential value of...
This study aims to compare the experiences of women and men of different age groups with regard to their first autism spectrum disorder (ASD) diagnosis, symptoms, treatment, and gender roles to inform our understanding in clinical practice of differences as well as similarities. Semi-structured interviews were conducted amongst 22 women (n = 12) an...
We developed a Dutch questionnaire called the Autistic Women’s Experience (AWE) and compared its psychometric properties to the Autism Spectrum Quotient (AQ). Whilst attenuated gender differences on the AQ have been widely replicated, this instrument may not fully capture the unique experience of autistic women. The AWE was co-developed with autist...
Background:
Attention-deficit/hyperactivity disorder (ADHD) has been associated with hyperfocus, a transient experience of enhanced attentional focus and diminished awareness of time and the environment.
Aims:
This study aims to investigate the association between the frequency, duration and pervasiveness of hyperfocus across different situation...
“Een ieder weet wat aandacht is”, stelde de Amerikaanse psycholoog en filosoof William James al in 1890. Vandaag de dag is er in de neuropsychologie veel kennis verworven over de structuur van aandacht als cognitief fenomeen. Recent psychometrisch onderzoek met de Everyday Life Attention Scale (ELAS) wijst uit dat de structuur van aandacht in het d...
Objective
This comprehensive review examined sex differences in prescription rates and efficacy or effectiveness of pharmacotherapy treatment in girls and women with attention deficit hyperactivity disorder (ADHD), while identifying gaps in the scientific knowledge on this topic.
Method
A rigorous electronic database search was carried out in orde...
Background
Effectiveness studies indicate various classroom management strategies (CMSs) that are helpful for students with attention-deficit/hyperactivity disorder (ADHD), but little is known about teachers’ experiences with these CMSs in school practice.
Objective
This study examined primary and secondary school teachers’ reported frequency of u...
Terwijl affectieve empathie verwijst naar de automatische neiging om gevoelens van de ander over te nemen wanneer die emoties toont, verwijst cognitieve empathie naar een meer bewust aan te sturen vermogen om het perspectief van een ander in te nemen (o.a. theory of mind genoemd). Of vrouwen empathischer (affectief dan wel cognitief) zijn dan manne...
The Everyday Life Attention Scale (ELAS) is a sensitive and reliable self-report questionnaire assessing attentional capacities of respondents in nine different situations of daily life. The ELAS has the potential to add relevant information to the clinical evaluation of attention deficits, to guide treatment planning, as well as to evaluate treatm...
Children who have symptoms of Attention Deficit/Hyperactivity Disorder (ADHD) often experience disruptive and off-task behavior and lower school performance than would be expected based on their cognitive abilities. These behavior and achievement difficulties are a challenge to teachers, who often provide inclusive education for children with ADHD....
Schaken is een van oudsher klassiek bordspel waarbij veel cognitieve vaardigheden nodig zijn, zoals concentratie, planning en inhibitie. Daarom zijn het vaak de slimme kinderen die kiezen voor schaakles of zelfs eerder toegang krijgen tot het volgen van schaakles, binnen en buiten school. Maar zijn het de slimme kinderen die schaaklessen gaan volge...
This study describes the development and utility of a new self-report measure of attentional capacities of adults with Attention Deficit Hyperactivity Disorder (ADHD): the Everyday Life Attention Scale (ELAS). Different from previous attention scales, attentional capacities are rated for nine everyday situations. Study 1 investigated the factor str...
Based on the Empathizing–Systemizing (E–S) theory, it was hypothesized that the underrepresentation of female students in the physical sciences and the underrepresentation of males in the social sciences relates to differences in E–S cognitive style between the sexes. This hypothesis was tested in 115 physical science students and 155 social scienc...
Studies in children with ADHD suggest impairments in social cognitive functions, whereas studies in adults with ADHD are scarce and inconclusive. The aim of this study was to investigate the relationship between ADHD traits and self-reported social cognitive style in a sample of adults from the general population. For this purpose, a community samp...
Spontaneous eye blink rate is modulated by task demands and internal state, and is demonstrated to reflect central dopamine activity. Also, spontaneous eye blinks are strategically timed around salient stimuli. This study investigates whether children with attention deficit hyperactivity disorder (ADHD) show reduced blink rates, blink modulation an...
As attention–deficit/hyperactivity disorder (ADHD) is one of the most frequently diagnosed developmental disorders in childhood, effective yet safe treatment options are highly important. Recent research introduced physical exercise as a potential treatment option, particularly for children with ADHD. The aim of this review was to systematically an...
Objective
Children with attention deficit hyperactivity disorder (ADHD) experience many peer interaction problems and are at risk of peer rejection and victimisation. Although many studies have investigated problematic peer functioning in children with ADHD, this research has predominantly focused on boys and studies investigating girls are scant....
Although deficits in Executive Functioning (EF) are reported frequently in young individuals with Autism Spectrum Disorders (ASD), they remain relatively unexplored later in life (>50 years). We studied objective performance on EF measures (Tower of London, Zoo map, phonetic/semantic fluency) as well as subjective complaints (self- and proxy report...
Objective:
The study investigated whether baseline plasma oxytocin (OXT) concentrations might moderate the effects of nasally administered OXT on social orienting.
Methods:
Thirty-one males with Autism spectrum disorder (ASD) and thirty healthy males participated in a double-blind placebo-controlled crossover trial. After administration of the c...
Introduction:
There is limited research on Autism Spectrum Disorders (ASD) in females. Although the empathy construct has been examined thoroughly in autism, little attention has been paid to empathy in adult women with this condition or to gender differences within the disorder.
Objective:
Self-reported empathy in adult women with ASD was exami...
Autism spectrum disorder (ASD) is marked by impairments in social-emotional situations, executive functioning, and behavioral regulation. These symptoms may be related to deficits in performance monitoring, i.e., the ability to observe and evaluate one's own behavior and performance which is necessary for the regulation of future behavior. The pres...
Children with attention-deficit/hyperactivity disorder (ADHD) often exhibit problem behavior in class, which teachers often struggle to manage due to a lack of knowledge and skills to use classroom management strategies. The aim of this meta-analytic review was to determine the effectiveness of several types of classroom interventions (antecedent-b...
Aandachtstekortstoornis met hyperactiviteit (ADHD) wordt geassocieerd met meer risicovol gedrag in het dagelijks leven, wat mogelijk verklaard kan worden door cognitieve en motivationele beperkingen. Om meer inzicht in dit verband te krijgen, werd de literatuur geraadpleegd over de prestaties op goktaken bij personen met ADHD. Tegen de verwachtinge...
Volwassenen met aandachtstekortstoornis met hyperactiviteit (ADHD) hebben vaak moeite met tijdmanagement en het nakomen van afspraken. Een belangrijke functie voor tijdmanagement is tijdwaarneming, die weer samenhangt met de werking van het kortetermijn- en het werkgeheugen. De onderliggende mechanismen van tijdmanagement bij volwassenen met ADHD z...
Objectives:
Whole Body Vibration (WBV) is a passive exercise method known to have beneficial effects on various physical measures. Studies on adults furthermore demonstrated beneficial effects of WBV treatment on cognition (e.g. inhibition). The present study replicated these findings in healthy children and examined acute effects of WBV treatment...
Objective:
The study investigated the effects of nasally administered oxytocin on neurophysiological orienting to empathy-evoking pictures in normally intelligent male adults with and without an autism spectrum disorder (ASD). It further investigated whether these effects might be moderated by the individual's approach and avoidance tendencies.
M...
The 'Empathy Quotient' (EQ) and 'Systemizing Quotient' (SQ) are used worldwide to measure people's empathizing and systemizing cognitive styles. This study investigates the psychometric properties of the Dutch EQ and SQ in healthy participants (n = 685), and high functioning males with autism spectrum disorder (n = 42). Factor analysis provided sup...
Sluggish cognitive tempo (SCT) oftewel een vertraagd cognitief tempo is op het moment een veel besproken onderwerp binnen het kader van de aandachtstekortstoornis met hyperactiviteit (ADHD). SCT is een sociaal-emotionele stijl die wordt gekenmerkt door ‘dagdromen’, ‘in de war zijn’, ‘in het niets staren’, ‘vertraagd reageren’ en ‘ongemotiveerd zijn...
Objective
This study investigated the effect of social relevance in affective pictures on two orienting responses, i.e. the evoked cardiac response (ECR), and a long latency cortical evoked potential (LPP) and whether this effect would differ between males and females. Assuming that orienting to affective social information is fundamental to experi...
In recent years, there is an increasing awareness that individuals may purposely feign or exaggerate symptoms of attention deficit hyperactivity disorder (ADHD) to gain external incentives, including access to stimulant drugs or special academic accommodations. There are vast consequences of undetected feigned ADHD such as substantial costs covered...
Objectives
Since the elimination of items associated with Sluggish Cognitive Tempo (SCT) during the transition from DSM-III to DSM-IV from the diagnostic criteria of Attention-deficit Hyperactivity Disorder (ADHD), interest in SCT and its associated cognitive as well as emotional and social consequences is on the increase. The current review discu...
The aim of this review was to gain insight into the relationship between Attention deficit hyperactivity disorder (ADHD) and risky performance in gambling tasks and to identify any potential alternate explanatory factors.
PsycINFO, PubMed, and Web of Knowledge were searched for relevant literature comparing individuals with ADHD to normal controls...
Current models of ADHD suggest abnormal reward and punishment sensitivity, but the exact mechanisms are unclear. This study aims to investigate effects of continuous reward and punishment on the processing of performance feedback in children with ADHD and the modulating effects of stimulant medication.
15 Methylphenidate (Mph)-treated and 15 Mph-fr...
Topographical maps of the feedback P2 (170–220 ms). Topographical maps of the feedback P2 in the interval of 170–220 ms after feedback onset on gain, no won, no loss and loss trials, separated for the TD, Mph-treated and Mph-free ADHD groups.
(TIF)
Topographical maps of the LPP (450–800 ms). Topographical maps of the LPP in the interval of 450–800 ms after feedback onset on gain, no win, no loss and loss trials, separated for the TD, Mph-treated and Mph-free ADHD groups.
(TIF)
Topographical maps of the FRN (260–360 ms). Topographical maps of the feedback related negativity (FRN) in the interval of 260–360 ms after feedback onset on gain, no won, no loss and loss trials, separated for the TD, Mph-treated and Mph-free ADHD groups.
(TIF)
Time on task effects on accuracy and RT separated for the TD, Mph-treated and Mph-free ADHD groups. As the task duration was ∼60 minutes, time on task may have had a differential influence on the task performance, and therefore on the brain processes, in the TD and ADHD groups. In order to check whether this may have influenced the outcomes, time o...
Topographical maps of the FRN difference potentials (260–360 ms). Topographical maps of the difference potentials for the feedback related negativity (FRN) in the interval of 260–360 ms after feedback onset for the gain minus no gain comparison and the no loss minus loss comparison, separated for the TD, Mph-treated and Mph-free ADHD groups.
(TIF)
Het vakgebied van de klinische neuropsychologie is relatief jong en vooral de klinische kinderneuropsychologie moet deels nog tot wasdom komen. Veel kinderneuropsychologische diagnostiek is gekopieerd van, of ontleend aan, de volwassen klinisch neuropsychologische diagnostiek. Er is een landelijke specialistische postdoctorale opleiding in de klini...
Objective:
This study aimed to investigate sex differences in the temporal dynamics of experiencing empathy by using electrophysiological measurements.
Methods:
Twenty-five females and 27 males viewed 414 pictures of the International affective picture system varying in emotional valence (positive, negative and neutral) and presence of humans (h...
Although the 10-repeat (10R) variant of the dopamine transporter gene (DAT1 or SLC6A3) is suggested to be a risk allele for Attention Deficit Hyperactivity Disorder (ADHD) no relationships between DAT1 and measures of cognition in children with ADHD have yet been demonstrated. We studied neurophysiological correlates of performance monitoring durin...
Attention Deficit Hyperactivity Disorder (ADHD) is a developmental disorder that has previously been related to a decreased sensitivity to errors and feedback. Supplementary to the traditional performance measures, this study uses autonomic measures to study this decreased sensitivity in ADHD and the modulating effects of medication. Children with...
Applying a probabilistic learning task we examined the influence of functional polymorphisms of the serotonin transporter gene (5-HTTLPR) and the D2 dopamine receptor gene (DRD2/ANKK1) on error and feedback processing by measuring electrocortical event-related potentials (ERPs) in 10- to 12-year-old children.
Three pairwise group comparisons were c...
Performance monitoring was investigated in typically developing (TD) children, children with Autistic Spectrum Disorder (ASD), and Methylphenidate (Mph)-treated and medication-free children with Attention Deficit Hyperactivity Disorder (ADHD).
Subjects performed a feedback-based learning task. Event-related Potentials (ERPs) time locked to response...
In this study we measured event-related potentials (ERPs) and evoked heart rate (EHR) to investigate performance monitoring in 10-12-year-old children. The children received feedback on their performance while conducting a probabilistic learning task. Error-related ERP components time-locked to the response increased in amplitude when the children...
Aandachtstekortstoornis met hyperactiviteit (ADHD) en Autisme Spectrum Stoornis (ASS) zijn ontwikkelingsstoornissen die in het handboek voor de psychiatrie staan omschreven als twee duidelijk verschillende classificaties. Echter, in de klinische praktijk alsook op neuropsychologisch niveau zijn ze vaak lastig te onderscheiden. Eerder onderzoek geef...
