Yvonne Chan

Northwestern University | NU · Department of Urology

Large animal testing and clinical trials using bioengineered bladder for augmentation have revealed that large grafts fail due to insufficient blood supply. To address this critical issue, an in vivo staged implant strategy was developed and evaluated to create autologous, vascularized bioengineered bladder tissue with potential for clinical transl...

Purpose: Bladder fullness and urgency are difficult to express for some patients. We hypothesized that images on a pictorial urgency scale would correlate with International Continence Society (ICS) standard verbal descriptors and bladder volume. Materials and methods: Aim 1. Toilet trained children and their parents were tested, excluding those...

Introduction: The Malone antegrade continence enema (MACE) procedure is effective in management of fecal incontinence and intractable constipation. Stomal incontinence and stenosis are the most common issues reported, and a recent large study of imbricated MACE procedures reports a surgical revision rate of 17%. The laparoscopic approach is now wi...

Purpose of review: Spina bifida is caused by incomplete neural tube closure during the first trimester. This condition may lead to bowel and bladder dysfunction as well as truncal weakness and motor anomalies. Presentations vary between myelomeningoceles and lipomeningoceles and may result in different outcomes. This review seeks to explore our cu...

Many pathological processes including neurogenic bladder and malignancy necessitate bladder reconstruction, which is currently performed using intestinal tissue. The use of intestinal tissue, however, subjects patients to metabolic abnormalities, bladder stones, and other long-term sequelae, raising the need for a source of safe and reliable bladde...

Introduction: Patient age and hospital volume have been shown to affect perioperative outcomes after pediatric pyeloplasty. However, there are few multicenter studies that focus on outcomes at teaching hospitals, where many of the operations are performed. Objective: The goal was to determine if surgical approach, age, case volume, or other fact...

Erectile dysfunction is a common and complex disease that has biological, clinical, and sociological significance. Scientific research with cell cultures, organ baths, and animal models has significantly advanced our understanding of the physiology of penile erection and common pathways involved in erectile dysfunction. Such studies have paved the...

Purpose: Both pediatric urologists and pediatric surgeons perform hernia repairs, hydrocelectomies and orchiopexies. We hypothesized that surgeons perform more incarcerated and female hernia repairs while urologists perform more orchiopexies and hydrocelectomies. Methods: The Vizient-AAMC Faculty Practice Solutions Center® database was queried f...