Yusuf Alif Pratama

Yusuf Alif Pratama
Airlangga University | UNAIR

Doctor of Pharmacy Candidate

About

15
Publications
1,011
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31
Citations
Introduction
Yusuf is a Doctoral Student of Pharmaceutical Sciences, Faculty of Pharmacy Universitas Airlangga. Now, He is doing his research on allergy, immunology, and pharmacology
Skills and Expertise

Publications

Publications (15)
Article
Full-text available
Background: Dyslipidemia is a lipid metabolic disorder that increases the risk of cardiovascular disease, typically marked by abnormalities in triglycerides (TG), low-density lipoprotein (LDL), and total cholesterol (TC), along with decreased high-density lipoprotein (HDL) levels. This study explored the potential of quercetin, a natural substance,...
Article
Full-text available
Food allergies are a global health problem that continues to grow annually, with a prevalence of more than 10%. Shrimp allergy is the most common and life-threatening allergy. There is no cure for food allergies, but shrimp allergen extract (SAE) offers promise as a treatment through allergen-specific immunotherapy (AIT). However, whether SAE induc...
Article
Full-text available
Subchondral defects are often caused by trauma involving cartilage damage, leading to subsequent damage to the underlying bone, specifically the subchondral region. Bilayer scaffolds made from biomaterials, such as bovine hydroxyapatite, possess biocompatible and biodegradable properties that mimic the natural environmental conditions of target tis...
Article
Context: Graptophyllum pictum (L.) Griff. leaves (GPL) are traditionally used in Indonesia to treat hemorrhoids, and the anti-hemorrhoid activity of the ethanolic extract of G. pictum leaves (GPLE) has been proven scientifically. However, since it contains a variety of compounds, both hydrophilic and lipophilic, which has diverse solubility, absorp...
Article
Aims This study aims to develop an anti-aging nanoformulation with Curcuma heyneana extract as bioactive substance. Background Curcuma heyneana Valeton & Zipj extract has been proven in previous research to have antioxidant, anti-ageing, anti-inflammatory and wound healing properties, which makes it a potential bioactive material for anti-ageing a...
Article
Full-text available
Background: The different sequences of the allergen protease can induce different immunogenicity for the development of immunotherapy. Dermatophagoides pteronyssinus that has Der p1 as major protein will be developed as local allergen to be immunotherapy for treating rhinitis allergy. Objective: This study aims to optimize and standardize the local...
Article
Full-text available
Background: Food allergies have become more common in the last decade. Shrimp is one of the most dominant food allergy triggers in Asian countries, including Indonesia. After ingesting allergens, B cells will produce allergen-specific Immunoglobin E (IgE). In the sensitization period, repeated allergen exposure promotes Mast Cell (MC) degranulatio...
Article
Full-text available
Background: Allergy is a hypersensitivity reaction that is generally mediated by Immunoglobulin E (IgE). More than 25% of the world's population is suspected of having these various diseases, and the prevalence and progression of these diseases have continued to increase significantly in recent years. Among these allergyrelated diseases, allergic...
Article
Allergen extract as allergen-specific immunotherapy (AIT) is the only causative therapy and provides protection or tolerance to an allergen in the long term. However, allergen extracts from different countries may have different effectiveness. This study aimed to evaluate the effectiveness of Indonesian shrimp allergen extract (SAE) as an immunothe...
Article
Osteoblasts, cells derived from mesenchymal stem cells (MSCs) in the bone marrow, are cells responsible for bone formation and remodeling. The differentiation of osteoblasts from MSCs is triggered by the expression of specific genes, which are subsequently controlled by pro-osteogenic pathways. Mature osteoblasts then differentiate into osteocytes...
Article
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Bone grafts a commonly used therapeutic technique for the reconstruction and facilitation of bone regeneration due to fractures. BHA–GEL (bovine hydroxyapatite–gelatin) pellet implants have been shown to be able accelerate the process of bone repair by looking at the percentage of new bone, and the contact between the composite and bone. Based on t...
Article
Full-text available
Background and aim: Perennial allergic rhinitis (AR) is a chronic upper respiratory disease, with inflammation mediated by immunoglobulin E in the nasal mucosa caused by house dust mites. Recently, allergen immunotherapy showed promising allergic healing in patients with a definite history of sensitization. Based on this finding, a product was dev...
Article
Full-text available
Background: In developing a pharmaceutical product, it is necessary to conduct pre-clinical and clinical trials to ensure its safety and effectiveness. The toxicity test is conducted to assess the safety of a substance to determine its toxic effect of the substance. Objective: This study aims to determine the acute and subchronic toxicity of admini...
Article
Pada era globalisasi, banyak orang bepergian dengan berbagai keperluan, terutama perjalanan liburan. Peningkatan jumlah perjalanan memicu banyaknya orang yang bepergian terkena penyakit selama atau setelah melakukan perjalanan. Hal ini disebabkan orang-orang tersebut kurang memiliki pengetahuan tentang pre-travel health preparation. Untuk mengetahu...

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