Yun-Ju Claire Chen

Verified

Yun-Ju verified their affiliation via an institutional email.

Learn more

Verified

Yun-Ju verified their affiliation via an institutional email.

Learn more

• Doctor of Philosophy
• Assistant Professor at Chang Gung University

Assessing autistic traits alongside co‐occurring emotional/behavioral concerns (EBCs) is challenging due to their overlap in clinical presentations, which can vary by age and sex. This study aimed to investigate domain‐specific associations between autistic traits and EBCs–including anxiety, affective, attention‐deficit/hyperactivity, and oppositio...

Early sensory differences may cascade into later social-communication difficulties in autism, yet their impacts on broader functional outcomes have remained understudied. This study aimed to conduct a comprehensive investigation into the longitudinal impacts of sensory patterns, including sensory hyperresponsiveness, hyporesponsiveness, and sensory...

Participation in daily activities is often linked to functional independence and well-being, yet individual variability in participation and factors associated with that variation have rarely been examined among autistic youth. We applied latent profile analysis to identify subgroups of youth based on parent-reported activity participation frequenc...

Sensory-based subtypes among autistic children have been well documented, but little is known about longitudinal sensory subtypes beyond autistic populations. This prospective study aimed to identify subtypes based on trajectories of parent-reported sensory features measured at 6-19 months, 3-4, and 6-7 years of age among a community-based birth co...

This prospective study examined the latent growth trajectories of sensory patterns among a North Carolina birth cohort (N = 1517; 49% boys, 87% White) across infancy (6–19 months), preschool (3–4 years), and school years (6–7 years). Change rates of sensory hyper- and hyporesponsiveness better differentiated children with an autism diagnosis or ele...

The use of parent-report screeners for early detection of autism is time- and cost-efficient in clinical settings but their utility may vary by respondent characteristics. This study aimed to examine the degree to which infants’ age and sex impacted parental reports of early behavioral signs of autism captured by the First Years Inventory Version 3...

Although participating in research is often presented as something that can ‘help others in the future’, research participants may also benefit from accessing and understanding their own research data. However, participant attitudes toward receiving individual data via research reports are under researched. This study examined participant perceptio...

Introduction The developmentally variable nature of autism poses challenges in providing timely services tailored to a child’s needs. Despite a recent focus on longitudinal research, priority-setting initiatives with stakeholders highlighted the importance of studying a child’s day-to-day functioning and social determinants of health to inform clin...

Researchers increasingly employ longitudinal trajectory methods to understand developmental pathways of people on the autism spectrum across the lifespan. By assessing developmental or health-related outcome domains at three or more timepoints, trajectory studies can characterize their shape and varying rates of change over time. The purpose of thi...

Background: The Washington Group/UNICEF Child Functioning Module (WG/UNICEF CFM) was developed to assess functional difficulties among children and youth in national household surveys. The objective of this study was to examine the latent structure of the WG/UNICEF CFM using a graded response scale in a nationally representative sample of children...

Introduction This study examined the prevalence of functional difficulties and associated factors in Canadian children/youth aged 5 to 17 years diagnosed with autism spectrum disorder (ASD). Methods We analyzed data from the 2019 Canadian Health Survey on Children and Youth (CHSCY), a nationally representative survey of Canadian children/youth tha...

Introduction Cette étude porte sur la prévalence des difficultés fonctionnelles et des facteurs connexes chez les enfants et les jeunes canadiens de 5 à 17 ans ayant reçu un diagnostic de trouble du spectre de l'autisme (TSA). Méthodologie Nous avons analysé les données tirées de l’Enquête canadienne sur la santé des enfants et des jeunes (ECSEJ)...

Background Previous research has demonstrated heterogeneous adaptive outcomes across the autism spectrum; however, the current literature remains limited in elucidating turning points and associated factors for longitudinal variability (chronogeneity). To address these empirical gaps, we aimed to provide a finer‐grained characterization of trajecto...

Infants at elevated likelihood of developing autism display differences in sensory reactivity, especially hyporeactivity, as early as 7 months of age, potentially contributing to a developmental cascade of autism symptoms. Caregiver responsiveness, which has been linked to positive social communication outcomes, has not been adequately examined wit...

Background Aberrant attention patterns have been commonly reported in autistic children. However, few studies have examined attention to non-social stimuli varying in salience and complexity using eye-tracking technology, as well as their links to clinical sensory features. Method Forty-one children [16 with autism spectrum disorder (ASD), 10 with...

Importance: Although three sensory factors (hyperresponsiveness [HYPO]; hyporesponsiveness [HYPER]; and sensory interests, repetitions, and seeking behaviors [SIRS]) have been demonstrated among a wide age range of clinical populations, they have not been well validated in the general population, especially with a large community sample of young ch...

Early detection of autism risk in the community is critical to increasing families' access to early intervention, yet few measures have been developed and tested for the general population of infants <16 months to tap a broader range of autism risk constructs. This study aimed to (a) examine the factor structure of the First Years Inventory, versio...

Recent advances in longitudinal methodologies for observational studies have contributed to a better understanding of Autism as a neurodevelopmental condition characterized by within-person and between-person variability over time across behavioral domains. However, this finer-grained approach to the study of developmental variability has yet to be...

Past research has demonstrated the ubiquitous presence and early emergence of sensory patterns, including hyperresponsiveness (HYPER), hyporesponsiveness (HYPO), and sensory interests, repetitions, and seeking behaviors (SIRS) in children with autism spectrum disorder (ASD), as well as the potential role of sensory processing as a key building bloc...

Date Presented Accepted for AOTA INSPIRE 2021 but unable to be presented due to online event limitations. This paper tests the structure of the First Years Inventory (FYI 3.1), a measure of social communication (SC) and sensory regulation (SR) and whether the structure varies over age; data collection was done on a community sample of 1,893 childre...

Date Presented 04/13/21 Sensory processing challenges are measured by caregiver report and clinician observation and affect many people with autism spectrum disorder and their caregivers. It is unclear how caregiver stress influences the correlation between scores on caregiver report and observational measures. The present analysis explores correla...

Date Presented 03/28/20 Sensory-processing challenges are measured by caregiver report and clinician observation and affect many people with autism spectrum disorder and their caregivers. It is unclear how caregiver stress influences the correlation between scores on caregiver reports and observational measures. The present analysis explored correl...

Date Presented 03/27/20 The analysis in this paper tests the utility of the FYI 3.1 as an autism screening tool and how that utility varies over age. Initial screening was done on a community sample of 1,893 children between 8 and 16 months of age. Sensitivity and positive predictive value were tested over a range of specificity from 85 to 99%. Pri...

Rationale: Emerging research on interventions for infants at elevated likelihood of ASD is driven by arguments that initiating targeted interventions in infancy could prevent full ASD symptom expression, or attenuate severity. Recent innovations involve testing “pre-emptive” interventions with infant siblings of children with ASD, infants with gen...

Date Presented 04/06/19 The current study aims to examine the utility of the First Years Inventory, a parent-report screener for early identification of autism spectrum disorder (ASD), as a potential tool for distinguishing ASD from other developmental delays. Despite being rarely addressed by previous studies in the field, the differentiation betw...

Date Presented 4/19/2018 The First Years Inventory is a parent-report screening designed to identify infants aged 9–15 mo who may be at risk for a later diagnosis of autism spectrum disorder. This study examined the developmental sensitivity of items using a large community sample (N = 5,796) to increase the utility of this screening in clinical se...

Date Presented 4/20/2018 The First Year Inventory–Lite is a brief parent-report measure created to reduce the clinical burden of a longer screening tool for autism spectrum disorder (ASD). Twenty-five items related to social–communication and sensory–regulatory functions were examined to develop cut points predictive of ASD outcomes at age 3. Prima...

A short screening tool for early identification of social communication and sensory regulatory risk markers of autism spectrum disorder (ASD) would be beneficial in clinical settings such as occupational therapy. • The FYI-Lite 1 is a subset of 25 items from the First Years Inventory (FYI) 2 , a parent-report screener for infants at-risk for ASD, t...

Despite the challenges of achieving adequate sensitivity in screening at 12 months 1 , early identification of autism is essential for obtaining early services, which may improve developmental outcomes 2. • The First Years Inventory version 3.1 (FYI) 3 is a newly revised parent-report screener 2 designed to identify infants at around one year of ag...

There is an increasing awareness about the importance of translation from basic scientific findings into practical application for efficiently improving human health, especially in the pharmaceutical industry. In the field of neurorehabilitation, however, the bench-to-bedside process continues to be developing, and thus most of the therapeutic inte...