Yuming Guo

Yuming Guo
Monash University (Australia) · School of Public Health and Preventive Medicine

MD, PhD

About

685
Publications
277,021
Reads
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56,546
Citations
Introduction
Global Environmental Health, Environmental Epidemiology, climate change, air pollution, machine learning, exposure assessment, time series, meta analysis, multi-country study, Editorial Board of PLOS Medicine, EHP, EI, and The Innovation.
Additional affiliations
May 2020 - December 2028
University of Melbourne
Position
  • Professor (Adjunct)
March 2017 - December 2025
The University of Queensland
Position
  • Professor (Adjunct)
February 2016 - February 2017
The University of Queensland
Position
  • Senior Researcher
Education
January 2010 - April 2012
Queensland University of Technology
Field of study
  • Environmental Epidemiology/Biostatistics
August 2006 - July 2009
Peking University
Field of study
  • Environmental Health

Publications

Publications (685)
Article
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Objectives To better understand the burden of air pollution on deaths, we examined the effects of air pollutants on years of life lost (YLL) in Beijing, China. Design Retrospective regression analysis using daily time series. Setting 8 urban districts in Beijing, China. Participants 80 515 deaths (48 802 male, 31 713 female) recorded by the Beijin...
Article
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Although studies have provided estimates of premature deaths attributable to either heat or cold in selected countries, none has so far offered a systematic assessment across the whole temperature range in populations exposed to different climates. We aimed to quantify the total mortality burden attributable to non-optimum ambient temperature, and...
Article
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Background Exposure to cold or hot temperatures is associated with premature deaths. We aimed to evaluate the global, regional, and national mortality burden associated with non-optimal ambient temperatures. Methods In this modelling study, we collected time-series data on mortality and ambient temperatures from 750 locations in 43 countries and f...
Article
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Background Heatwaves are a critical public health problem. There will be an increase in the frequency and severity of heatwaves under changing climate. However, evidence about the impacts of climate change on heatwave-related mortality at a global scale is limited. Methods and findings We collected historical daily time series of mean temperature...
Article
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This study aimed to investigate the association between air pollutants and methylation of peripheral brain-derived neurotrophic factor (BDNF) promoters. A total of 101 individuals were recruited in this panel study. BDNF promoter methylation was detected by bisulfite-PCR amplification and pyrosequencing. Participants’ exposure to air pollutants was...
Article
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Background Identifying how greenspace impacts the temperature-mortality relationship in urban environments is crucial, especially given climate change and rapid urbanization. However, the effect modification of greenspace on heat-related mortality has been typically focused on a localized area or single country. This study examined the heat-mortali...
Article
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Background Long-term exposure to fine particles ≤2.5 μm in diameter (PM 2.5 ) has been linked to cancer mortality. However, the effect of wildfire-related PM 2.5 exposure on cancer mortality risk is unknown. This study evaluates the association between wildfire-related PM 2.5 and site-specific cancer mortality in Brazil, from 2010 to 2016. Methods...
Article
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There is little research on how long-term exposure to independent and multiple air pollutants changes cardiometabolic risk in adults. In addition, previous studies focused on only the effect of one or two lifestyles on cardiometabolic risk. The evidence on the interactive effects of the lifestyle score and exposure to independent and mixtures of ai...
Article
Background Despite emerging recognition of the benefits of green and blue spaces on human health, evidence for their effect modifications on heat–mortality associations is limited. We aimed to investigate the effect modifications of green and blue spaces on heat–mortality associations among different age and sex groups and at different heat levels....
Article
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Background Onchocerciasis is a disease caused by infection with Onchocerca volvulus, which is transmitted to humans via the bite of several species of black fly, and is responsible for permanent blindness or vision loss, as well as severe skin disease. Predominantly endemic in parts of Africa and Yemen, preventive chemotherapy with mass drug admini...
Article
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Aims To evaluate the associations between residential greenness and glucocorticoid levels and whether air pollutants and sex modify the relationship between greenness and glucocorticoid level in Chinese rural adults. Methods We collected cross-sectional survey data from 6055 participants from the Henan Rural cohort. The three-year average resident...
Article
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Background Both ambient ozone exposure and residential greenness are linked to the aging process. However, their interactive effect on molecular biomarkers of aging (telomere length (TL) and mitochondrial DNA copy number (mtDNA-CN)) remains unclear. Methods This study was conducted among 6418 rural Chinese adults. The concentration of ambient ozon...
Article
An increasing body of evidence has linked greenspace and various health outcomes in children and adolescents, but the conclusions were inconsistent. For this review, we comprehensively summarized the measurement methods of greenspace, resultant health outcomes, and potential mechanisms from epidemiological studies in children and adolescents (aged...
Article
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Cancer has become the leading cause of premature death in many counties in recent decades. Previous studies showed plenty of evidence that control of modifiable risk factors would reduce the cancer burden. Since modifiable risk factors could be eliminated by changing the lifestyles of individuals, a greater uptake of modifiable risk factors is crit...
Article
Background Evidence remains limited and inconsistent for the associations between sustained air pollution exposures and diabetes development. This study aimed to determine the potential effects of particulate matter with a diameter of ≤10 micrometres (PM10), particulate matter with a diameter of ≤2.5 micrometres (PM2.5) and nitrogen dioxide (NO2) o...
Article
Italy is among the countries with the highest ozone concentration in Europe. However, the mortality burden of ozone and related economic loss has not been fully characterized. This study aimed to estimate the ozone-mortality association in Italy and evaluate attributable mortality burden and related economic loss in 2015–2019. We collected daily al...
Article
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Background: Globally, transport and unintentional injuries persist as leading preventable causes of mortality and morbidity for adolescents. We sought to report comprehensive trends in injury-related mortality and morbidity for adolescents aged 10-24 years during the past three decades. Methods: Using the Global Burden of Disease, Injuries, and...
Article
Background The burden of gastrointestinal infections related to hot ambient temperature remains largely unexplored in low-to-middle income countries which have most of the cases globally and are experiencing the greatest impact from climate change. The situation is particularly true in Brazil. Objectives Using medical records covering over 78 % of...
Article
Spontaneous preterm birth (SPB) has drawn public attention due to its increasing incidence and adverse effects on fetal growth. Effect of copper (Cu) imbalance in maternal bodies on the risk of SPB remains a subject of debate, and the related mechanisms are still unraveled. Here we applied natural stable copper isotopes to explore the underlying as...
Article
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Depression is the most common mental illness and contributes to a huge disease burden. However, few studies have examined the association between ambient temperature on depression. In this study, a three times repeated survey was conducted in 24 communities nationwide in China, through a face-to-face interview. Weather and air pollution data were c...
Article
Introduction Long-term exposure to air pollution is associated with lung function impairment. However, whether long-term improvements in air quality could improve lung function is unclear. Objectives To examine whether the reduction of long-term air pollution was associated with lung function improvement among Chinese young adults. Methods We con...
Article
Background Limited studies investigated the association of prenatal exposure to PM2.5 and fetal growth measured by ultrasound with inconsistent results. No study evaluated the effect of PM2.5 constituents on fetal growth in utero. We aimed to investigated whether prenatal exposure to PM2.5 and its constituents was associated with fetal growth measu...
Preprint
BACKGROUND Particulate matter (PM) is detrimental to the respiratory and circulatory system. However, no study was found evaluating the lag effects of weekly exposure to fine PM from preconception to delivery on the risk of hypertensive disorders of pregnancy (HDP). OBJECTIVE To investigate the lag effect windows of PMs on the risk of HDP in week...
Article
Background: Although studies have provided the estimates of floods-diarrhoea associations, little is known about the lag effect, effect modification, and attributable risk. Based on Sichuan, China, an uneven socio-economic development province with plateau, basin, and mountain terrains spanning different climatic zones, we aimed to systematically...
Article
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The association of ozone with type 2 diabetes mellitus (T2DM) is uncertain. Moreover, the moderating effect of physical activity on this association is largely unknown. This study aims to evaluate the independent and combined effects of ozone and physical activity on T2DM and fasting blood glucose (FBG) in a Chinese rural adult population. A total...
Article
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Background Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quantify the burden of type 2 diabetes attributable to PM2·5 originating from ambient and household air p...
Article
Context Recent studies in specific population subgroups (e.g., pregnant women) have suggested PM exposure increases the risk of hyperuricemia. However, no studies have examined this in the general population. Furthermore, the underlying mechanism through which PM impacts hyperuricemia risk is poorly understood. Objective To assess the association...
Article
Background With the increasing frequency and duration of wildfires over the past 10 years, the effects of wildfire on health need to be better understood. Long-term exposure to particulate matter less than 2·5 μm in diameter (PM2·5) has been linked to cancer mortality. However, the long-term effects of wildfire-related PM2·5 exposure on cancer mort...
Article
Background Evidence is limited for the association between outdoor light at night (LAN) and mild cognitive impairment (MCI), a transitional stage between normal aging and dementia and Alzheimer's disease in the elderly. In this study, the association between outdoor LAN and MCI was examined based on a multi-city study among veterans in China. Meth...
Article
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Rationale: The associations between ambient coarse particulate matter (PM2.5-10) and daily mortality is not fully understood at a global scale. Objectives: To evaluate the short-term associations between PM2.5-10 and total, cardiovascular, and respiratory mortality across multiple countries/regions worldwide. Methods: We collected daily mortal...
Article
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Purpose of Review Health effects of long-term exposure to ambient PM 2.5 vary with regions, and 75% of the deaths attributable to PM 2.5 were estimated in Asia-Pacific in 2017. This systematic review aims to summarize the existing evidence from cohort studies on health effects of long-term exposure to ambient PM 2.5 in Asia-Pacific. Recent Finding...
Article
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Heatwaves are Australia’s deadliest natural hazard. Anthropogenic climate change has increased the intensity, frequency and duration of heatwaves over Australia in the past several decades and these trends are projected to worsen in the future. Despite the strong knowledge of heatwave characteristics and their projected changes, there remains a gap...
Article
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Aims: To examine the temporal trends of the association between heat exposure and hospitalizations for renal disease in Queensland, Australia, between the summer season of 1 December 1995 and 31 December, 2016. Methods: A total of 238,427 de-identified hospitalization records for renal disease were collected from Queensland Health. Meteorological d...
Article
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Background: Older adults with type 2 diabetes are at higher risk of developing common geriatric syndromes and have a lower quality of life. To prevent type 2 diabetes in older adults, it's unclear whether the health benefits of physical activity (PA) will be influenced by the harms caused by increased exposure to air pollution during PA, especiall...
Article
Objective Quantifying the spatial and socioeconomic variation of mortality burden attributable to particulate matters with aerodynamic diameter ≤ 2.5 µm (PM2.5) has important implications for pollution control policy. This study aims to examine the regional and socioeconomic disparities in the mortality burden attributable to long-term exposure to...
Article
Previous studies assessing adverse health have traditionally focused on a single environmental exposure, failing to reflect the reality of various exposures present simultaneously. Air pollution, ambient temperature and greenness have been proposed as critical environmental factors associated with metabolic syndrome (MetS). However, evidence explor...
Article
Background Long-term exposure to PM2.5 is proved to be linked with mortality. However, limited studies have estimated the PM2.5 related loss of life expectancy (LLE) and its changing trends. How much life expectancy would be improved if PM2.5 pollution is reduced to the new WHO air quality guideline (AQG) level is unclear. Methods Data on deaths f...
Article
Air pollution addresses short-term health effects on morbidity, especially for children. Assessing the impacts of air pollution on elementary students is critical for developing preparedness response strategies for this sensitive group. In the 2016–17 academic year, up to 687,748 groups of illness-related absence records and the information on whet...
Article
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To reduce the high disease burden caused by air pollution, World Health Organization (WHO) issued a new air quality guideline (AQG) on the 22nd September 2021. A timely quantitative assessment of health benefits by meeting these targets is a key measure to advocate and inform national and regional disease control policies. We collected daily major...
Article
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Importance: Healthy sleep has an important role in the physical and mental health of children. However, few studies have investigated the association between outdoor artificial light at night (ALAN) and sleep disorders in children. Objective: To explore the associations between outdoor ALAN exposure and sleep disorders in children. Design, sett...
Preprint
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Background Australia implemented an mRNA-based booster vaccination strategy against the COVID-19 Omicron variant in November 2021. We aimed to evaluate the effectiveness and cost-effectiveness of the booster strategy over 180 days. Methods We developed a decision-analytic Markov model of COVID-19 to evaluate the cost-effectiveness of a booster str...
Article
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Background Increased mortality risk is associated with short-term temperature variability. However, to our knowledge, there has been no comprehensive assessment of the temperature variability-related mortality burden worldwide. In this study, using data from the MCC Collaborative Research Network, we first explored the association between temperatu...
Article
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RNA binding proteins (RBPs) are critical for the post-transcriptional control of RNAs and play vital roles in a myriad of biological processes, such as RNA localization and gene regulation. Therefore, computational methods that are capable of accurately identifying RBPs are highly desirable and have important implications for biomedical and biotech...
Article
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Health risks of chronic exposure to microcystins (MCs), a family of aquatic contaminants produced mainly by cyanobacteria, are critical yet unsolved problems. Despite a few epidemiological studies, the metabolic profiles of humans exposed to MCs remain unknown, hindering the deep understanding of the molecular toxicity mechanisms. Here, sensitive n...
Article
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Famine exposure or air pollution is linked to type 2 diabetes mellitus (T2DM). However, their combined effects on T2DM remain largely unknown. A total of 11,640 individuals were obtained from the Henan Rural Cohort Study. According to their birthdate, participants were divided into three famine exposure subgroups: fetal exposed, childhood exposed,...
Article
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Prior studies have linked prenatal exposure to air pollutants with adverse pregnancy outcomes, but few have empirically and experimentally investigated the causal effects on adverse outcomes, abortion, and fetal abnormalities. The aim of this study was to estimate the combined effects of prenatal exposure to gaseous air pollutants (CO, SO 2 , and N...
Article
Background A growing body of studies have reported the health benefits of greenness. However, less is known about the potential beneficial effects of residential greenness on gut microbiota, which is essential to human health. In this study, we aim to examine the association between residential greenness and gut microbiota in a population-based coh...
Article
Global warming has been changing the planet’s climate pattern, leading to increasing frequency, intensity and duration of extreme weather events and natural disasters. These climate-changing events affect various health outcomes adversely through complicated pathways. This paper reviews the main signs of climate change so far, e.g., suboptimal ambi...
Article
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Heatwaves are associated with increased mortality and are exacerbated by the urban heat island (UHI) effect. Thus, to inform climate change mitigation and adaptation, we quantified the mortality burden of historical heatwave days in Sydney, Australia, assessed the contribution of the UHI effect and used climate change projection data to estimate fu...
Article
Climate change and an increase in the number of major fire events occurring around the world have drawn attention to the importance of understanding the association between air pollution events and mental health. In 2014, the Morwell open-cut brown coal mine adjacent to the Hazelwood power station in the Latrobe Valley region of Victoria, Australia...
Article
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Objective: Emerging evidence has shown that ambient air pollution affects brain health, but little is known about its effect on epileptic seizures. This work aimed to assess the association between daily exposure to ambient air pollution and the risk of epileptic seizures. Methods: This study used epileptic seizure data from two independent data...
Article
Background: Long-term exposure to ambient ozone links to aging biomarkers and increased risk for atherosclerotic cardiovascular diseases (ASCVD). However, the roles of aging biomarkers in the association of long-term exposure to ambient ozone with ASCVD are unclear. Methods: 5298 participants completed the questionnaire and physical examination...
Article
Background Human beings and society are experiencing substantial consequences caused by non-optimum temperatures. However, limited studies have assessed the economic burden of premature deaths attributable to non-optimum temperatures. Objectives To characterize the association between daily mean temperature and the economic burden of premature dea...
Article
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Long-term ozone exposure may lead to non-communicable diseases and increase mortality risk. However, cohort-based studies are relatively rare, and inconsistent exposure metrics impair the credibility of epidemiological evidence synthetization. To provide more accurate meta-estimations, this study updates existing systematic reviews by including rec...
Article
Background Living near green spaces may benefit various health outcomes. However, no studies have investigated the greenness-bone linkage in the general population. Moreover, to which extent ambient air pollution (AAP), physical activity (PA), and body mass index (BMI) mediate this relationship remains unclear. We aimed to explore the association b...
Article
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High surrounding road density could increase traffic-related air pollution, noise and the risk of traffic injuries, which are major public health concerns for children. We collected geographical data for all childcare centers (16,146) in Australia and provided the data on the road density surrounding them. The road density was represented by the ch...
Article
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Epidemiological analyses of health risks associated with non-optimal temperature are traditionally based on ground observations from weather stations that offer limited spatial and temporal coverage. Climate reanalysis represents an alternative option that provide complete spatio-temporal exposure coverage, and yet are to be systematically explored...