Yugo Shobugawa

Yugo Shobugawa
Niigata University · Division of International Health

MD, PhD

About

127
Publications
9,913
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1,743
Citations
Citations since 2017
84 Research Items
1172 Citations
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2017201820192020202120222023050100150200250300
2017201820192020202120222023050100150200250300

Publications

Publications (127)
Article
Full-text available
Introduction: A 2015 study showed a decreasing trend in the incidence of osteoporotic hip fractures in Niigata Prefecture, Japan, which had been increasing. This study aimed to investigate the incidence of osteoporotic hip fractures in 2020, determine the long-term change in the incidence of hip fractures from 1985 to 2020, and assess whether the...
Article
PurposeVisual impairment is a possible cause of physical frailty. Reduced physical activity (PA) may be involved in the pathway from visual impairment to physical frailty, although the association between vision and objectively measured PA among older adults remains unclear. This study examined the sex-specific association of subjective vision with...
Article
Full-text available
Objectives This study aims to investigate whether there is a differential association between socioeconomic status (SES) and adherence to hypertension medication among older adults in rural and urban areas in Myanmar and assess what type of SES is associated with a difference. Design Cross-sectional study using baseline data from the Japan Geronto...
Article
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People have a preference for, and feel better in, beautiful natural environments. However, there are no epidemiological studies on the association between neighborhood beauty and neuroimaging measures. We aimed to determine association between neighborhood beauty and regional brain volume. Participants were 476 community-dwelling older adults from...
Article
Background: Recently, several studies reported that pneumonia might increase the risk of cognitive decline and dementia due to increased frailty. Objectives: This study aims to examine the association between a history of pneumonia and subsequent dementia risk. Methods: Participants were 9952 aged 65 years or older Japanese men and women from...
Article
Background: We investigated the association between tooth loss and structural brain volume and its mediating effect on the association between tooth loss and cognitive function in older Japanese. Methods: A cross-sectional study was conducted by using the data of 494 randomly sampled community-dwelling individuals aged 65-84 years living in Toka...
Preprint
Objectives: People have a preference for, and feel better in, beautiful natural environments. However, there are no epidemiological studies on the association between exposure to neighborhood beauty and neuroimaging measures, such as regional brain volume. This study aimed to determine association between subjective and objective neighborhood beaut...
Article
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Purpose: Handgrip strength (HGS) is indicative of overall physical health among older adults. A decrease in HGS may be associated with an increased risk of disease. The aim of this study is to determine the factors associated with HGS among older adults in Malaysia. Patients and methods: One thousand two hundred four (1204) participants from urb...
Article
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Background Acute lower respiratory infection (ALRI) remains the leading cause of death in children worldwide, and viruses have been the major cause of ALRI. In Myanmar, ALRI is associated with high morbidity and mortality in children, and detailed information on ALRI is currently lacking. Methods This prospective study investigated the viral aetio...
Article
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Few studies have examined whether objective or subjective economic status (ES) has a greater association with the happiness of older adults, despite concerns regarding the growing economic cost of morbidity and their functional dependence in developing countries with aging populations. Thus, this study examined whether objective/subjective ES was a...
Article
Background Adverse childhood experiences (ACEs) can affect later-life health outcomes via brain structural differences. However, there is no sufficient empirical evidence about whether brain morphological differences remain until old ages. Objective We examined the association between ACEs and brain volumes among older individuals. Participants a...
Article
Objectives : Having gratitude is associated with reduced social isolation and depression, which are risk factors for dementia. However, it is unknown whether gratitude is directly associated with cognitive function. This study aimed to determine associations between gratitude and cognitive function and to elucidate the underlying biological mechani...
Article
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Objectives : There is no consensus regarding the impact of population density on the transmission of respiratory viral infections such as COVID-19 and seasonal influenza. We aimed to determine the correlation between population density and incidence and duration of COVID-19 transmission. Methods : We retrospectively collected publicly available da...
Article
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Background: Recent findings indicate that leisure activity (LA) delays cognitive decline and reduces the risk of dementia. However, the association between LA and brain volume remains unclear. This study aimed to examine the association between LA variety and brain volume with a focus on the hippocampus and gray matter. Methods: Data were obtained...
Article
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Background: Childhood maltreatment can impede gratitude, yet little is known about the older population and its moderators. The aim of this study is to clarify the association between childhood maltreatment and levels of gratitude of the older population, and the moderating effect of social ties on the association. Methods: We analyzed the data...
Article
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Purpose: Older people often have chronic diseases which require a continuity of care over the long term. Countries undergoing population aging need to ensure that older people are receiving the care they need. This study assesses the prevalence of, reasons for, and factors associated with unmet healthcare needs among older people individuals in Ma...
Article
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Shah SA, Safian N, Ahmad S, et al. J Multidiscip Healthc. 2021;14:2931–2940. The authors have advised there was misuse of the word “elderly” in the title and some sentences within the main text. Additionally, the Ethics Approval and Funding sections have also been updated. The paper title should read from “Unmet Healthcare Needs Among Elderly Malay...
Article
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Background: School closures are a subject of debate during the present coronavirus disease 2019 (COVID-19) pandemic. Because children are not the main driver of COVID-19 transmission in the community, school education must be prioritized in conjunction with appropriate infection prevention and control measures, as determined by local COVID-19 inci...
Article
Background Physical inactivity can be associated adversely with markers of eye health, but little is known about how ophthalmic disease (OD) may be related to sedentary behaviour (SB) and different intensities of physical activity in older adults. We compared device-assessed time spent in SB, light-intensity PA (LPA), and moderate-to-vigorous physi...
Article
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Abstract Background Non-pharmaceutical interventions (NPIs), such as sanitary measures and travel restrictions, aimed at controlling the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), may affect the transmission dynamics of human respiratory syncytial virus (HRSV). We aimed to quantify the contribution of the sales of hand hygiene pr...
Article
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Background: Homebound status is one of the most important risk factors associated with functional decline and long-term care in older adults. Studies show that neighborhood built environment and community social capital may be related to homebound status. This study aimed to clarify the association between homebound status for community-dwelling ol...
Preprint
Full-text available
Background Acute lower respiratory infection (ALRI) remains the leading cause of death in children worldwide, and viruses have been the major causative factors of ALRI after the introduction of bacterial conjugate vaccines. In Myanmar, ALRI is associated with high morbidity and mortality in children. However, detailed information on ALRI is current...
Article
Full-text available
Objective Inequalities exist between the 23-valent pneumococcal polysaccharide vaccination (PPSV23) rate in each municipality among Japanese older adults. Exploring individual-level and community-level intervenable factors is necessary to improve the vaccination rates. We examined the associations between community-level and individual-level social...
Article
Full-text available
Pneumonia is a leading cause of mortality among older adults worldwide. Recently, several studies reported that frailty was associated with mortality among older adults hospitalized due to respiratory infectious diseases, including pneumonia. However, it is unknown whether frailty is associated with susceptibility to and severity of pneumonia in fu...
Article
Full-text available
Happiness is an essential component to experience healthy ageing. Hence, understanding the factors that contribute to happiness is important. This study aimed to determine the factors associated with happiness among the elderly population in Malaysia. In this study, 1204 respondents were recruited from urban and rural areas in Selangor. A face-to-f...
Article
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Few studies have examined the effects of inbound overseas travelers and meteorological conditions on the shift in human respiratory syncytial virus (HRSV) season in Japan. This study aims to test whether the number of inbound overseas travelers and meteorological conditions are associated with the onset week of HRSV epidemic season. The estimation...
Article
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Background: The hippocampus is a brain structure important for memory and cognitive function. Physical activity may help prevent hippocampal atrophy. However, few studies have measured sedentary behavior (SB) and intensity-specific physical activity using an accelerometer. This study aimed to examine the cross-sectional associations of objectively-...
Article
Full-text available
The aim of the study was to investigate rural–urban differences in depressive symptoms in terms of the risk factors among older adults of two regions in Myanmar to provide appropriate intervention for depression depending on local characteristics. This cross-sectional study, conducted between September and December, 2018, used a multistage sampling...
Article
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The overall coronavirus disease secondary attack rate (SAR) in family members was 19.0% in 10 prefectures of Japan during February 22-May 31, 2020. The SAR was lower for primary cases diagnosed early, within 2 days after symptom onset. The SAR of asymptomatic primary cases was 11.8%.
Article
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Background: Increasing the coverage of vaccinations recommended by the World Health Organization in the older adult population is an urgent issue, especially in the context of avoiding co-epidemics during the current coronavirus disease 2019 crisis. The aim of this study was to examine factors associated with the quality of perceived patient-physic...
Article
Full-text available
Low objective socioeconomic status (SES) has been correlated with poor physical and mental health among older adults. Some studies suggest that subjective SES is also important for ensuring sound physical and mental health among older adults. However, few studies have been conducted on the impact of both objective and subjective SES on mental healt...
Preprint
Full-text available
Pneumonia is a leading cause of mortality among older adults worldwide. Recently, several studies reported that frailty was associated with mortality among older adults hospitalized due to respiratory infectious diseases, including pneumonia. However, it is unknown whether frailty is associated with susceptibility to and severity of pneumonia in fu...
Article
Full-text available
The need for assistance among the elderly is rising, which poses challenges for healthcare systems. Thus, this study aims to determine the factors associated with the need for assistance in the daily living activities of Malaysia′s elderly population. A total of 1204 elderly individuals, aged 60 years and above, were recruited. An interview was con...
Article
Aim To examine associations of intensity-specific physical activity and bout-specific sedentary time with frailty status among Japanese community-dwelling older adults, taking into account the interrelationships of these behaviors. Methods Participants were 511 community-dwelling older adults. Physical activity and sedentary time were assessed usi...
Preprint
Full-text available
Background Few studies have examined whether objective or subjective economic status (ES) has a greater effect on the happiness of older adults in developing countries with ageing populations. This study examined whether objective/subjective economic status (ES) is associated with happiness in older adults in Myanmar. Method A multistage, random sa...
Article
Full-text available
Purpose Myanmar is rapidly ageing. It is important to understand the current condition of older adults in the country. To obtain such information, we conducted home-visit surveys to collect data for evaluating social determinants of health on older adults in Yangon (representative of an urban) and Bago (representative of a rural) regions of Myanmar...
Article
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We conducted a prospective, multicenter, non-randomized observational study to assess the duration of fever and symptoms of influenza A/H1N1pdm09 and A/H3N2 infected children < 19 years old treated with either baloxavir or oseltamivir. Additionally, these symptoms were investigated in association with pre- and post-baloxavir treatment-emergent poly...
Article
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Background: Levels of physical activity change throughout the year. However, little is known to what extent activity levels can vary, based on accelerometer determined sedentary and physically-active time. The aim of this longitudinal study was to examine older adults' activity changes from a non-snowfall season to a subsequent snowfall season, wi...
Article
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Sekentei (social appearance) is a Japanese concept that describes a person’s sense of implicit societal pressure to conform to social norms. However, evidence of a relationship between sekentei and health outcomes is sparse. This study examined the association between sekentei and cognitive function among community-dwelling older Japanese people. B...
Article
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We analyzed 3,184 cases of coronavirus disease in Japan and identified 61 case-clusters in healthcare and other care facilities, restaurants and bars, workplaces, and music events. We also identified 22 probable primary case-patients for the clusters; most were 20-39 years of age and presymptomatic or asymptomatic at virus transmission.
Article
Full-text available
Poor sleep is associated with lifestyle, however, few studies have addressed the association between sleep quality and the neighborhood environment. This study aimed to investigate the associations between living environment factors and sleep quality in older people. Participants were community-dwelling people aged ≥65 years who participated in the...
Article
Full-text available
Background: We investigated the association between age, duration of clinical symptoms and viral shedding in outpatient children infected with respiratory syncytial virus (RSV) in Japan. Methods: Outpatients younger than 2 years of age, with suspected RSV infection between 2014 and 2018, were enrolled in the study. Following informed consent, na...
Article
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Background Neuraminidase inhibitors (NAIs) effectively treat influenza. The clinical effectiveness of four NAIs (oseltamivir, zanamivir, laninamivir, and peramivir) was evaluated against influenza A/H1N1pdm09, A/H3N2, and B viruses. Additionally, fever duration in patients infected with oseltamivir-resistant influenza A/H1N1pdm09 with the H275Y mut...
Article
Full-text available
Background: The concept of sekentei (social appearance), defined as sensitivity about one's reputation, reflects Japanese behavioral principles and involves pressure to conform to social norms, particularly among people living in rural areas. However, data regarding the relationship between sekentei and health behaviors are sparse. In this study,...
Article
Full-text available
Background: Physical activity can help to protect against cognitive decline in older adults. However, little is known about the potential combined relationships of time spent in sedentary behavior (SB), light-intensity physical activity (LPA), and moderate-to-vigorous physical activity (MVPA) with indices of cognitive health. We examined the cross-...
Article
Full-text available
Background: Studies have shown that rural residents face disadvantages concerning medical access and socio-economic conditions. However, the social determinants of health among older people in rural areas are still unclear. The Neuron to Environmental Impact across Generation (NEIGE) study investigated the social determinants of health among older...
Article
Objectives: To clarify changes in the incidence of cervical lesions in rheumatoid arthritis (RA) patients with advanced treatment and the impact of cervical lesions on the patients’ quality of life (QOL). Methods: Incidence of radiographic cervical lesions in 1333 RA patients in 2015 was compared with that in our 1999 survey. The association betwee...
Article
Full-text available
Purpose To investigate the prevalence of and factors associated with dysfunctional low back pain (LBP) in patients with rheumatoid arthritis (RA). Methods This cross-sectional study included 1276 RA outpatients from two hospitals. The Roland–Morris Disability Questionnaire was used to address the functional–dysfunctional state criterion. Clinical...
Article
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Background: We estimated influenza vaccine effectiveness (VE) in 2015-2016 season against medically attended, laboratory-confirmed influenza, when quadrivalent inactivated vaccine (IIV4) was first introduced in Japan, using test-negative case-control design. Influenza A(H1N1)pdm09 cocirculated with B/Yamagata and B/Victoria during the study period...
Article
Full-text available
Early detection of dementia provides opportunities for interventions that could delay or prevent its progression. We developed the Japanese version of the Quick Mild Cognitive Impairment (Qmci-J) screen, which is a performance-based, easy-to-use, valid and reliable short cognitive screening instrument, and then we examined its validity. Community-d...
Article
Full-text available
We investigated the circulation patterns of human influenza A and B viruses in Myanmar between 2010 and 2015 by analyzing full HA genes. Upper respiratory tract specimens were collected from patients with symptoms of influenza-like illness. A total of 2,860 respiratory samples were screened by influenza rapid diagnostic test, of which 1,577 (55.1%)...
Data
Demographic and clinical data and accession numbers of sequences generated in this study. (DOCX)
Data
Bayes factor and Posterior Probability of migration events of influenza viruses A(H1N1)pdm09, A(H3N2), and B, Myanmar and other countries, 2010–2015. (DOCX)
Data
Regression of root-to-tip genetic distance against sampling date of A(H3N2)-HA gene. The coefficient correlation of 0.88 and R2 of 0.77 show a positive correction between genetic divergence and sampling time. The data set of A(H3N2)-HA gene is therefore fit for phylogenetic molecular clock analysis in BEAST. (TIF)
Data
Spatio-temporal dispersion pattern of HA of influenza A(H1N1)pdm09 in Asia, Oceania, Europe, North America South America, and Africa. The snapshots show the dispersal pattern of A(H1N1)pdm09 virus of HA from 2010 to 2015. Connections between different countries represent branches in the MCC tree along which the relevant location transition occurs....
Data
Animation of the phylogeographic dispersion pattern of HA of influenza A(H3N2) in Asia, Oceania, Europe, North America, South America, and Africa. The dispersal pattern of A(H3N2) virus of HA from 2010 to 2015 were analyzed and visualized with the spatial phylogenetic reconstruction of evolutionary dynamics using data-driven documents (SpreaD3) v0....
Data
Primers and probes used for detection of influenza B isolates. (DOCX)
Data
Yearly distribution of samples and Influenza virus isolates in Pyinmana, Myanmar, 2010–2015. (DOCX)
Data
Regression of root-to-tip genetic distance against sampling date of A(H1N1)pdm09-HA gene. The coefficient correlation of 0.87 and R2 of 0.75 show a positive correction between genetic divergence and sampling time. The data set of A(H1N1)pdm09-HA gene is therefore fit for phylogenetic molecular clock analysis in BEAST. (TIF)
Data
Animation of the phylogeographic dispersion pattern of HA of influenza B in Asia, Oceania, Europe, North America, South America, and Africa. The dispersal pattern of B virus of HA from 2010 to 2015 were analyzed and visualized with the spatial phylogenetic reconstruction of evolutionary dynamics using data-driven documents (SpreaD3) v0.9.7.1. Conne...
Data
The region and collection time of sequences involved in phylogeographic analysis. (DOCX)
Data
Yearly distribution of samples and Influenza virus isolates in Yangon, Myanmar, 2010–2015. (DOCX)
Data
Yearly distribution of samples and Influenza virus isolates in Pyin Oo Lwin, Myanmar, 2010–2015. (DOCX)
Data
Animation of the phylogeographic dispersion pattern of HA of influenza A(H1N1)pdm09 in Asia, Oceania, Europe, North America, South America, and Africa. The dispersal pattern of A(H1N1)pdm09 virus of HA from 2010 to 2015 were analyzed and visualized with the spatial phylogenetic reconstruction of evolutionary dynamics using data-driven documents (Sp...
Data
Regression of root-to-tip genetic distance against sampling date of influenza B-HA gene. The coefficient correlation of 0.70 and R2 of 0.49 show a positive correction between genetic divergence and sampling time. The data set of influenza B-HA gene is therefore fit for gene phylogenetic molecular clock analysis in BEAST. (TIF)
Data
Spatio-temporal dispersion pattern of HA of influenza A (H3N2) in Asia, Oceania, Europe, North America South America, and Africa. The snapshots show the dispersal pattern of A(H3N2) virus of HA from 2010 to 2015. Connections between different countries represent branches in the MCC tree along which the relevant location transition occurs. Location...
Data
Spatio-temporal dispersion pattern of HA of influenza B in Asia, Oceania, Europe, North America South America, and Africa. The snapshots show the dispersal pattern of influenza B virus of HA from 2010 to 2015. Connections between different countries represent branches in the MCC tree along which the relevant location transition occurs. Location cir...
Article
Purpose: The purpose of this study was to investigate the association of early social environment with Kawasaki disease (KD). Methods: We analyzed the data of children aged up to 10 years derived from the 21st Century Longitudinal Survey in Newborns (n = 41,872) in Japan. Parental education, total household income, and family size were obtained...