Youngrong Park

Youngrong Park
Pohang University of Science and Technology | POSTECH · Department of Chemistry

About

12
Publications
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552
Citations

Publications

Publications (12)
Article
In this study, we designed and synthesized far-red- and near-infrared-emitting Cu-doped InP-based quantum dots (QDs), and we also demonstrated their highly specific and sensitive biological imaging ability. Cu-doped InP/ZnS (core/shell) QDs were prepared using the hot colloidal synthesis method in the organic phase. The ZnS shell passivates the sur...
Article
Full-text available
Two imaging probes can be co-used for colonoscopic diagnosis: a fluorescent probe that ratiometrically switches between two colors in response to λ-glutamyltranspeptidase activity and an antibodyquantum dot probe. As shown by Ki Hean Kim, Sungjee Kim, Seung-Jae Myung, and co-workers in article number 1703450, co-application of two probes affords ac...
Article
Full-text available
A rapid and accurate molecular fluorescence imaging technique will greatly reduce cancer mortality by overcoming the detection limit of the naked eye in colonoscopy. Two imaging probes are reported that can be co-used for colonoscopic diagnosis: a fluorescent molecular probe, cresyl violet–glutamic acid derivative, that ratiometrically switches bet...
Article
Early detection of structural or molecular changes in dysplastic epithelial tissues is crucial for cancer screening and surveillance. Multi-targeting molecular endoscopic fluorescence imaging may improve noninvasive detection of precancerous lesions in the colon. Here, we report the first clinically compatible, wide-field-of-view, multi-color fluor...
Article
Photoluminescent quantum dots (QDs) promise many biomedical applications as a new class of optical probes showing unique optical properties such as high brightness, stability, and multiplexing ability. In this review, we focus on recent research interest of medically-translatable QDs for in vitro biomedical sensing and in vivo imaging. QD-based bio...
Article
The detection of colon cancer using endoscopy is widely used but the interpretation of the diagnosis is based on the clinician's naked eye. This is subjective and can lead to false detection. Here we developed a rapid and accurate molecular fluorescence imaging technique using antibody-coated quantum dots (Ab-QDs) sprayed and washed simultaneously...
Article
Full-text available
Facile and rapid one-pot synthesis for nearly monodisperse Cu2SnS3 and Cu2ZnSnS4 nanocrystals was developed using a heat-up method. Their crystalline phase and size were simultaneously controlled by judiciously choosing the sulfur precursor reactivity and the oleic acid content.
Article
Full-text available
We report a miniaturized probe-based combined two-photon microscopy (TPM) and optical coherence tomography (OCT) system. This system is to study the colorectal cancer in mouse models by visualizing both cellular and structural information of the colon in 3D with TPM and OCT respectively. The probe consisted of gradient index (GRIN) lenses and a 90°...
Article
Intravital imaging has provided molecular, cellular and anatomical insight into the study of tumor. Early detection and treatment of gastrointestinal (GI) diseases can be enhanced with specific molecular markers and endoscopic imaging modalities. We present a wide-field multi-channel fluorescence endoscope to screen GI tract for colon cancer using...
Article
The parallel and highly sensitive detection of biomolecules is of paramount importance to understand biological functions at the single cell level and for various medical diagnoses. Surface-engineered semiconductor quantum dots (QDs) have been demonstrated to act as a signal amplifiable reporter in immunoassays. This takes advantage of the QDs' rob...
Article
Layered double hydroxide (LDH)-quantum dot (QD) composites are synthesized via a room temperature LDH formation reaction in the presence of QDs. InP/ZnS (core/shell) QD, a heavy metal free QD, is used as a model constituent. Interactions between QDs (with negative zeta potentials), decorated with dihydrolipoic acids, and inherently positively charg...

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