Young J Kim

• Seoul National University

A 3D occupancy map that is accurately modeled after real-world environments is essential for reliably performing robotic tasks. Probabilistic volumetric mapping (PVM) is a well-known environment mapping method using volumetric voxel grids that represent the probability of occupancy. The main bottleneck of current CPU-based PVM, such as OctoMap, is...

We present a semiautonomous robotic pen-drawing system, called SSK, that is capable of creating pen art on a large nonplanar surface. Our robotic system relies on a seven-degree-of-freedom impedance-controlled manipulator with a three-degree-of-freedom holonomic mobile platform. We use a vector-graphics engine to take an artist's pen drawing as inp...

We present a new robotic drawing system based on stroke-based rendering (SBR). Our motivation is the artistic quality of the whole performance. Not only should the generated strokes in the final drawing resemble the input image, but the stroke sequence should also exhibit a human artist's planning process. Thus, when a robot executes the drawing ta...

TSP art is an art form for drawing an image using piecewise-continuous line segments with no crossings. This paper presents a multi-color robotic pen drawing system capable of drawing complicated TSP pen art on a planar surface. Given a colored, raster image, we first convert it into a set of points representing the original image's tone by control...

An interdisciplinary approach to antimicrobial resistance (AMR) is essential to effectively address what is projected to soon become a public health disaster. Veterinary medicine accounts for a majority of antimicrobial use, and mainly in support of industrial food animal production (IFAP), which has significant exposure implications for human and...

Feline chronic gingivostomatitis (FCGS) is a severe immune-mediated inflammatory disease with concurrent oral dysbiosis (bacterial and fungal). Broad-spectrum antibiotics are used empirically in FCGS. Still, neither the occurrence of antimicrobial-resistant (AMR) bacteria nor potential patterns of co-occurrence between AMR genes and fungi have been...

We propose a 3D face generative model with local weights to increase the model’s variations and expressiveness. The proposed model allows partial manipulation of the face while still learning the whole face mesh. For this purpose, we address an effective way to extract local facial features from the entire data and explore a way to manipulate them...

We propose a 3D face generative model with local weights to increase the model's variations and expressiveness. The proposed model allows partial manipulation of the face while still learning the whole face mesh. For this purpose, we address an effective way to extract local facial features from the entire data and explore a way to manipulate them...

Previous studies have suggested the involvement of viral and bacterial components in the initiation and progression of feline chronic gingivostomatitis (FCGS), but the role of fungi remains entirely unknown. This pilot study aimed to investigate the bacteriome and mycobiome in feline oral health and disease. Physical exams, including oral health as...

One challenge of legged locomotion on uneven terrains is to deal with both the discrete problem of selecting a contact surface for each footstep and the continuous problem of placing each footstep on the selected surface. Consequently, footstep planning can be addressed with a Mixed Integer Program (MIP), an elegant but computationally demanding me...

Probabilistic volumetric mapping (PVM) represents a 3D environmental map for an autonomous robotic navigational task. A popular implementation such as Octomap is widely used in the robotics community for such a purpose. The Octomap relies on octree to represent a PVM and its main bottleneck lies in massive ray-shooting to determine the occupancy of...

One challenge of legged locomotion on uneven terrains is to deal with both the discrete problem of selecting a contact surface for each footstep and the continuous problem of placing each footstep on the selected surface. Consequently, footstep planning can be addressed with a Mixed Integer Program (MIP), an elegant but computationally-demanding me...

We propose a novel RGB-D camera tracking system that robustly reconstructs hand-held RGB-D camera sequences. The robustness of our system is achieved by two independent features of our method: adaptive visual odometry (VO) and integer programming-based key-frame selection. Our VO method adaptively interpolates the camera motion results of the direc...

Encountered-type haptic rendering provides realistic, free-to-touch, and move-and-collide haptic sensation to a user. However, inducing haptic-texture sensation without complicated tactile actuators is challenging for encountered-type haptic rendering. In this paper, we propose a novel texture synthesizing method for an encountered-type haptic disp...

In this paper, we propose haptic interfaces based on force feedback to provide a physical painting experience to virtual reality users. Through this system, the user can create surface-based painting holding a haptic stylus, while utilizing both visual feedback from the worn HMD and haptic feedback during painting. In particular, the haptic interfa...

In this paper, we propose a novel penetration metric, called deformable penetration depth PDd, to define a measure of inter-penetration between two linearly deforming tetrahedra using the object norm. First of all, we show that a distance metric for a tetrahedron deforming between two configurations can be found in closed form based on object norm....

Considerable evidence suggests loss-of-function mutations in the chromatin remodeler CHD2 contribute to a broad spectrum of human neurodevelopmental disorders. However, it is unknown how CHD2 mutations lead to impaired brain function. Here we report mice with heterozygous mutations in Chd2 exhibit deficits in neuron proliferation and a shift in neu...

With virtual reality, digital painting on 2D canvas is now being extended to 3D space. In this paper, we generalize the 2D pixel canvas to a 3D voxel canvas to allow artists to synthesize volumetric color fields. We develop a deep and dynamic octree‐based painting and rendering system using both CPU and GPU to take advantage of the characteristics...

Traumatic brain injury is a major risk factor for many long-term mental health problems. Although underlying mechanisms likely involve compromised inhibition, little is known about how individual subpopulations of interneurons are affected by neurotrauma. Here we report long-term loss of hippocampal interneurons following controlled cortical impact...

We show a novel encountered‐type haptic system, H‐Wall, to enable haptic feedback using a manipulator of seven degrees of freedom suitable for simulating indoor virtual reality environments, which are characterized and confined by a set of vertical walls and revolving doors. At runtime, our system tracks hand motion using a red–green–blue depth sen...

The cover image, by Yaesol Kim et al., is based on the Special Issue Paper Encountered‐type Haptic Display for Large VR Environment using Per‐plane Reachability Maps, https://doi.org/10.1002/cav.1814.

In this paper, an effective, interactive grasping algorithm is proposed to provide physically realistic interactions in the virtual world. We have provided a solution to lacking dynamic control resulting in penetrations and frictionless contact due to kinematic virtual hand provided by hand‐tracking devices, by including a proxy hand in the system....

The proposed physics-based approach can generate stable and robust full-body animation of various gaits under different gravitational conditions. As input, this method takes motion-captured human motions in the Earth’s gravity and builds an inverted-pendulum on cart (IPC) control model, which is analyzed using the motion-captured data. The authors...

With increases of display resolution and graphical quality demands, global illumination techniques are sought after to meet such demands. However, global illumination algorithms have a long processing time on mobile devices, such as smartphones or tablet PCs. Besides the performance issue, the algorithms consume a large amount of battery-powered en...

With virtual reality, digital painting on 2D canvases is now being extended to 3D spaces. Tilt Brush and Oculus Quill are widely accepted among artists as tools that pave the way to a new form of art - 3D emmersive painting. Current 3D painting systems are only a start, emitting textured triangular geometries. In this paper, we advance this new art...

The study examined the differential mechanisms of mechanical allodynia and thermal hyperalgesia after injection of IL-1β into the orofacial area of male Sprague-Dawley rats. The subcutaneous administration of IL-1β produced both mechanical allodynia and thermal hyperalgesia. Although a pretreatment with iodoresiniferatoxin (IRTX), a transient recep...

This study examined the participation of central mitogen-activated protein kinases (MAPKs) in the central sensitization produced by a subcutaneous injection of interleukin-1β (IL-1β) in male Sprague-Dawley rats. Formalin-induced responses were evaluated 24 h after an IL-1β injection. A subcutaneous injection of 10 ng of IL-1β elevated the formalin-...

Umbilical cord blood (UCB), a rich source of hematopoietic stem cells, offers practical and ethical advantages. It has been reported that various adult stem cells transplanted into a damaged liver show characteristics of a hepatic lineage. In a previous study, we reported on novel UCB-derived adult stem cells, termed umbilical cord blood-derived mu...

Laryngeal carcinoma is the eleventh-most common form of cancer among men worldwide and is the second-most common malignancy of the head and neck. The primary functions of the larynx involve phonation, respiration, and deglutition but it also contributes to taste and smell by allowing the movement of air over the special sense organs. Thus, loss of...

In late midlife, heterosexual women report markedly lower levels of sexual satisfaction than heterosexual men. This article explored the social factors contributing to this difference, using data from 1,035 sexually-active heterosexual adults, aged 40-59 years, who participated in the National Health and Social Life Survey (NHSLS). Conducted in 199...

This article examines the relationship between gender and heterosexual partnering in midlife, using survey data from 1240 women and men aged 40 to 59. Although older ages are associated with lower numbers of sexual partners for both genders, larger proportions of women report having no partners, and at earlier ages than men. Sexual conservatism and...

Adherens junctions and desmosomes are critical for embryogenesis and the integrity of adult tissues. To form these junctions, classical cadherins interact via alpha- and beta-catenin with the actin cytoskeleton, whereas desmosomal cadherins interact with the intermediate filament system. Here, we used a hormone-activated mutant N-cadherin expressed...

Cadherins are expressed on the cell surface as a dimer in the membrane of one cell (cis dimer) that interacts with a cis dimer on an adjacent cell to form an adhesive trans dimer. It is well established that both cis and trans dimers must form for the cadherin to be an effective adhesion protein. In addition to their adhesive activity cadherins als...

Examined qualities of the therapeutic relationship as perceived by low-income children who were in treatment for serious emotional disorders and their mothers. Recent emphasis on engaging families in the treatment of their children highlights the importance of understanding processes that facilitate therapeutic partnerships. Therapeutic bonds (i.e....

Cadherins are calcium-dependent glycoproteins that function as cell-cell adhesion molecules and are linked to the actin cytoskeleton via catenins. Newly synthesized cadherins contain a prosequence that must be proteolytically removed to generate a functional adhesion molecule. The goal of this study was to examine the proteolytic processing of N-ca...

An important class of short-fiber reinforced composites is the sheet molding compound, which is recently developed and currently used in many engineering applications. Fatigue failure of the composites is a subject of major concern in design and cyclic crack propagation, is of particular significance in the fatigue life prediction of short fiber co...

The fatigue behaviour of six different hollow section T-joints subjected to out-of-plane bending moment was investigated experimentally using scaled steel models. The joints had circular brace members and rectangular chord members. Hot spot stresses and the stress concentration factors (SCFs) were determined experimentally. Fatigue testing was carr...

The relationship between women's employment and the risk of divorce is both complex and controversial. The role specialization (or interdependence) view of marriage argues that the gains to marriage for both partners decrease when both are in the labor force, and hence women's employment destabilizes marriage. In contrast, the economic opportunity...

Large quantities of porcine hepatocyte aggregates with various degrees of aggregation (DA) could be obtained by controlling the suspension periods (0, 9, 24, and 48 h), and by entrapping the hepatocyte aggregates in model materials of encapsulation such as Ca-alginate and type-I collagen gels. The effects of DA on liver-specific functions of hepato...

The purpose of the present study was to examine the responses of medullary dorsal horn neurons to microiontophoretic application of the -aminobutyric acid (GABA)A receptor antagonist, bicuculline. The mechanisms of bicuculline-induced hypersensitivity were also investigated. Extracellular recordings were made with the central barrel of a seven-barr...

Children with chronic illnesses have a heightened risk for mental health problems. To develop, implement, and evaluate child outcomes of a 15-month, community-based, family-support intervention designed to reduce risk for poor adjustment and mental health problems in children with 1 of 4 chronic illnesses (diabetes mellitus, sickle cell anemia, cys...

The purpose of this study was to examine the effects of a bleaching agent (30% hydrogen peroxide) on the surface of bovine enamel using a scanning electron microscope and a UV-VIS-NIR spectrophotometer. Five non-carious bovine incisors were bleached for 0, 1, 2 and 3 days using 30% hydrogen peroxide. The light reflectance spectrum was measured usin...

Mucinous gastric carcinoma (MGC) is a histopathologic subtype of gastric carcinoma with a poor prognosis. The purpose of this study was to compare the disease course of MGC with non-mucinous gastric carcinoma (NMGC) and study the clinicopathologic features that influence the prognosis of MGC patients. We reviewed the records of 2,383 patients with...

Fiber composite materials are widely used in aerospace industries due to their high specific strength and stiffness. Especially, the increasing use of polymer composite materials for injection of automobile components has led to a considerable interest in the application of stress pattern analysis by thermal emission to these composite materials. T...

This paper evaluates the fatigue fracture behavior of a chopped strand glass mat/polyester composite both in air and sea water. Bending fatigue(R=-1) was performed on dry and wet specimens, that is respectively in air and sea water. Where the pH concentration of sea water was controlled to 6.0, 8.2, 10.0 and the wet specimens were immersed in the s...

E- and N-cadherin are members of the classical cadherin family of proteins. E-cadherin plays an important role in maintaining the normal phenotype of epithelial cells. Previous studies from our laboratory and other laboratories have shown that inappropriate expression of N-cadherin by tumor cells derived from epithelial tissue results in conversion...

Dynamic multistate models can show realistic population dynamics over time, model complex cycles, and encompass the life history of a cohort. This paper uses a recently developed approach to obtain the analytic solution of a time-dependent multidimensional differential equation. The illustrative robust/frail model presented shows that the assumptio...

Carcinoembryonic antigen (CEA) has been widely accepted as a tumor marker useful in the diagnosis and management of colorectal carcinoma. When CEA levels are positive in patients with gastric carcinoma, they could be useful prognostic indicators. The value of CEA as a tumor marker for gastric carcinoma, however, remains a matter of controversy. The...

In this paper, we take a new approach to the question of whether or not intentions regarding future fertility affect fertility-related behavior. Our approach has three principal features: 1) it takes sterilization as its outcome, rather than pregnancy or birth; 2) it is based on a conceptual model in which fertility-related behavior is seen as dete...

Keloid and hypertrophic scars are fibrous dermal tumors characterized by overabundant collagen deposition. Previous studies demonstrated that exogenous transforming growth factor beta (TGF-beta) might increase collagen production in incisional wound models and in vitro. Using an in vivo model of human scar xenografts maintained in congenitally athy...

This research examines the impact of teenage childbearing on secondary school completion, while focusing on the problem of causal ambiguity in the relationships among self-determined behaviours. Techniques for dealing with the teenage childbearing problem are discussed, and results from these methods are compared. Data from the High School and Beyo...

Keloids, hypertrophic scars, and burn hypertrophic scars are all forms of proliferative scarring characterized by overabundant matrix formation. Recently these dermal proliferative disorders have been linked clinically to the cytokine transforming growth factor beta (TGF-beta), and in vitro tests have shown it to be responsible for the activation o...

Selectins are adhesion molecules that mediate calcium-dependent cell-cell interactions among leukocytes, platelets, and endothelial cells. The naturally occurring vascular ligands for the selectins are mostly mucin-type glycoproteins. Increased expression and altered glycosylation of mucins are known to be prominent features of carcinoma progressio...

: Keloids, hypertrophic scars, and burn hypertrophic scars are all forms of proliferative scarring characterized by overabundant matrix formation. Recently these dermal proliferative disorders have been linked clinically to the cytokine transforming growth factor beta (TGF-[beta]), and in vitro tests have shown it to be responsible for the activati...

The purpose of this study was to describe a new axial-pattern experimental flap model in the rat. Wistar rats weighing 200 to 250 g were used in the experiment. In 15 rats, the superficial anatomy of the ventral thoracic region was studied by anatomic dissection, dye injection, and microangiography, using 5 rats in each group. The anatomic studies...

We examine the relationship between fertility intentions and fertility behavior using a sample of 2,812 non-Hispanic Whites interviewed twice by the National Survey of Families and Households. Time 1 fertility intentions are strong and persistent predictors of fertility, even after controlling for background and life course variables. The effect is...

The analytic models used by family demographers would be strengthened by the concept of social capital, placed in the context of social exchange theory. Using that concept to designate resources that emerge from social ties, the authors advance five propositions: 1) social capital is a multidimensional attribute of an individual; 2) the dimensions...

A population's growth potential is significantly underestimated by conventional calculations of population momentum which assume an immediate drop to replacement level fertility. Here we assume that the growth rate of births linearly declines to zero over a specified time interval, and find simple and intuitively meaningful expressions for the size...

Pain management for partial-thickness burns and split-thickness skin graft donor sites remains a persistent problem. Topical capsaicin (trans-b-methyl-N-vanillyl-noneamide) has been successful for pain relief in postherpetic neuralgia, arthritis, and diabetic neuropathy. It is thought to work by inhibiting type C cutaneous factors and by releasing...

Selectins are adhesion receptors that normally recognize certain vascular mucin-type glycoproteins bearing the carbohydrate structure sialyl-Lewisx. The clinical prognosis and metastatic progression of many epithelial carcinomas has been correlated independently with production of tumor mucins and with enhanced expression of sialyl-Lewisx. Metastas...

Many aspects related to the biology and the effective therapy of proliferative scars have remained undefined, in part due to a lack of an accurate and reproducible animal model with which to systematically study them. This report describes a new model for investigating the pathophysiology and manipulation of human proliferative scars. Human prolife...

No abstract Abbreviations: Sia, sialic acid, type unspecified; Tn antigen, GalNAcα 1-O-Ser/Thr; T antigen, Galβ1-3GalNAcα-O-Ser/Thr; Sialyl LewisX, Siaα2-3Galβ1-4(Fucα1-3)GlcNAc; Sialyl Lewisa, Siaα2-3Galβ1-3(Fucα1-4)GlcNAc; Sialyl-Tn antigen, Siaα2-6GalNAcα1-O-Ser/Thr; FucT, fucosyltransferase; ST, sialyltransferase.

Population momentum and population aging occur when an initially growing population experiences a reduction in fertility to replacement level. Conceptually and empirically, momentum and aging express the same change, albeit on different scales. Fundamentally, they are two manifestations of the underlying process of demographic transformation. We co...

This paper advances a new approach that provides closed form expressions for the birth trajectory produced by a regime of changing vital rates. An exponentiated sinusoidal net maternity function is considered in detail, as populations with cyclically varying net maternity are of particular interest because of their connection to the Easterlin hypot...

Prevailing theories of fertility behavior do not explain what sustains fertility in industrialized countries. Extending James Coleman's concept of social capital, the authors argue that the social resource value of children is an important factor motivating child-bearing. Data for the United States from the 1987-88 National Survey of Families and H...

Starting with a sinusoidal birth function, we derive an explicit expression for the associated wave of net maternity (R(t)). The phase shift and relative amplification of R(t) depend heavily on the cycle length of oscillation (T) relative to the mean age of net maternity (mu) and on the amplitude of oscillation of the birth function. For short cycl...

Previous studies have shown that the mucin-type polypeptides GlyCAM-1, CD34, and MAdCAM-1 can function as ligands for L-selectin only when they are synthesized by the specialized high-endothelial venules (HEV) of lymph modes. Since sialylation, sulfation, and possibly fucosylation are required for generating recognition, we reasoned that other muci...

Stable population models, based on fertility and mortality rates that do not change over time, are too unrealistic and inflexible to capture the dynamics of many observed populations. Dynamic models, which allow vital rates to change over time, are needed to systematically analyze such populations. Here we examine dynamic—hyperstable—models with in...

Substantial regularities characterize the transition to stability that follows a shift from one set of vital rates to another. The new vital, rates interact with the population's initial age composition and generate birth waves whose amplitude and attenuation depend on the ratio of ultimate to initial growth and on the new pattern of stable net mat...

The authors studied three hypothesized explanations for reduced birth weights of infants born to US adolescent mothers--social disadvantage, biologic immaturity, and unhealthy behaviors during pregnancy. A hierarchical regression analysis was pursued to evaluate these explanations using data from the National Longitudinal Study of Youth on 1,754 fi...

To predict complex behavior in protein displacement systems of immobilized metal ion affinity chromatography (IMAC), numerical simulation of non-linear chromatography was developed and compared with the ideal solution of the model. The theoretical and experimental results demonstrate that the IMAC model can be successfully employed in predicting in...

A rigorous multicomponent isotherm for preparative immobilized metal affinity chromatography (IMAC) must consider the multipointed nature of adsorption, the possibility of steric hindrance of the stationary phase upon binding of macromolecules, and the role of the mobile-phase modifier. In this paper, the metal affinity interaction chromatography (...

The purification of recombinant thrombolytic protein from a crude fermentation broth mixture was examined in strong cation exchange (SCX) Chromatographic system. SCX system was shown to exhibit unique selectivity for the recombinant protein broth mixture. While SCX system showed lower total binding capacity for the recombinant protein than Anti-bod...

Metal affinity displacement chromatography was employed for the purification of proteins. The mobile phase modifier imidazole was shown to exhibit complex induced gradients in these displacement systems resulting in different imidazole microenvironments in each protein displacement zone. Furthermore, the induced imidazole gradient produced an eleva...

The purification of recombinant thrombolytic protein from a crude fermentation broth mixture was examined in antibody exchange (ABx) chromatographic system. ABx system was shown to exhibit unique selectivity for the recombinant protein broth mixture and higher total binding capacity for the recombinant protein than cation-exchange system. The resea...

The cyclically stable population relaxes the stable population assumption of fixed vital rates and replaces it with the assumption of a recurring sequence of schedules of vital rates. From any point (or stage) in one cycle of the sequence to the same stage in the next cycle, the cyclically stable population grows at a constant rate (λ). While the a...

The vertical distribution of background atmospheric aerosols was measured over south-central New Mexico as a part of the Atmospheric Lidar Verification Experiment (ALIVE) during four research field periods in the summers and winters of 1989 and 1990. Aerosol size distribution was measured from the surface up to 4500 m above sea level (asl) over the...