Yosra Yosra Zgueb

Yosra Yosra Zgueb
Razi Hospital · psychiatry "A"

About

75
Publications
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369
Citations
Citations since 2016
61 Research Items
363 Citations
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2016201720182019202020212022020406080100120140
2016201720182019202020212022020406080100120140

Publications

Publications (75)
Article
Aims The present survey aims to assess the overall mood disorder prevalence and identify associated socio-demographic and clinical factors in a Tunisian community sample, with special attention to the COVID-19 pandemic. Background Mood disorders are one of the leading causes of all non-fatal burden of disease, with depression being at the top of t...
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Introduction The era of the paternalisation of the patient is over, gradually giving way to new models, in particular that of “shared medical decision making”, with the aim of responding to the growing desires of the patient and giving priority to his autonomy. Objectives to establish the influence of the new active position of the patient in the...
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Introduction Clozapine use is not deprived of serious complications that can condition treatment strategies, particularly hematological. Recognizing the time it takes for these effects to set, can therefore help to better screen their appearance, improving healthcare. Objectives To study the time of onset of hematological adverse reactions in pati...
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Introduction Bipolar disorder (BD) is a chronic and recurrent illness frequently associated with functional deterioration and treatment challenges. High rates of thyroid dysfunction have been found in patients with BD, compared to the general population. Objectives To illustrate through a case-report the therapeutic challenges of treatment-resista...
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Introduction Approximately 30% of individuals diagnosed with schizophrenia suffer from treatment-resistant or refractory schizophrenia. The gold standard for treatment is clozapine. However, a significant number of patients discontinue clozapine treatment and this carries a poor prognosis. Objectives This study explores patients’ motives for cessa...
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Introduction Suicide attempts in late adolescence deserves special attention. Identifying particularities of suicidal behavior in this age group seems important in order to detect suicidal ideations. Objectives Describe the characteristics of suicide attempts in late adolescence among hospitalized patients. Methods This is a retrospective descrip...
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Introduction Much has been learned about SARS-CoV-2. However, the mechanism of short or long-term neuropsychiatric symptoms remains unclear. several hypotheses, including lack of oxygen caused by lung damage, inflammation affecting brain cells, or Lack of blood flow caused by swelling of the small blood vessels in the brain, have been advanced to e...
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Introduction Suicidal behavior remains an important clinical problem and a major cause of death in youth. Objectives The purpose of this study was to describe the epidemiological and clinical profile of adolescents with suicide attempts. Methods This is a retrospective descriptive study that focused on a population of Tunisian adolescents aged be...
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Introduction The complexity of the feeling of satisfaction makes its measurement complex, in this context our work aims to develop a simple and practical measurement tool to identify problems within the processes of psychiatric care in order to provide corrective interventions. Objectives to validate the psychometric properties of a scale designed...
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Introduction Treatment adherence, is defined as “the extent to which a person’s behavior — taking medication, following a diet, and/or executing lifestyle changes — corresponds with the agreed recommendations from a healthcare provider.” The course of patients with mental health is habitually chronic and based on an indefinite continuation of treat...
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Introduction The covid-19 pandemic is a difficult global phenomenon that causes a lot of anxiety and uncertainty. This situation has involved reactions of fear. Healthcare professionals are necessarily in contact with patients, but may find themselves torn between the duty to care and the duty to protect themselves and their relatives. Objectives...
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Introduction Clozapine is highly effective in patients with treatment-resistant schizophrenia but, to ensure optimal clinical response it is important to optimize its use and this depends on adequate pharmacological monitoring. Objectives Evaluate the therapeutic response rate according to clozapine plasma concentration. Methods It was a cross-se...
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Introduction In the literature, some studies consider psychiatric patients to be vulnerable to COVID-19, in contrast to other studies that find them rather protected. Objectives To determine the impact of the COVID 19 pandemic on patients undergoing psychiatric care. Methods This is a descriptive and cross-sectional study that took place in the p...
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Introduction Mixed states in mood disorders present significant clinical and prognostic challenges. Although the DSM-5 has broadened diagnostic criteria for mixed states with the development of the ‘mixed features’ specifier and its application to unipolar depressive disorders, some mixed episodes might still be overlooked. Objectives to evaluate...
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Introduction A delusion of pregnancy is defined as a fixed false belief that one is pregnant in the absence of any evidence to support the pregnant state. Different mechanisms have been advanced to explain this phenomenon. Objectives Herein, we present a case of hyperprolactinemia with delusion of pregnancy during the use of Amisulpride. Methods...
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Introduction The direct and indirect effects of the COVID-19 pandemic on the mental health of the population have become a concern in the field of research in psychiatry. First psychotic episodes following infection with SARS cov2 have been reported. Objectives Through a clinical case, we will illustrate the association of psychiatric symptoms wit...
Preprint
Background: Studies about two most used and validated instruments for the early detection of BD, the 32 - item Hypomania Checklist (HCL - 32) and the Mood Disorder Questionnaire (MDQ)screeners, in non-Western countries are scarce. This study aimed to explore the reliability, factor structure, and criterion validity of the Arabic versions in a sampl...
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Purpose Studies of mental illness stigma reduction interventions have been criticised for failing to evaluate behavioural outcomes and mechanisms of action. This project evaluates training for medical students entitled ‘Responding to Experienced and Anticipated Discrimination’ (READ), developed to focus on skills in addition to attitudes and knowle...
Preprint
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Background: Mental health and other health professionals working in mental health care may contribute to the experiences of stigma and discrimination among mental health service users, but can also help reduce the impact of stigma on service users. However the few studies of interventions to equip such professionals to be anti-stigma agents those t...
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Background Stigma among healthcare providers is a barrier to the effective delivery of mental health services in primary care. Few studies have been conducted in primary care settings comparing the attitudes of healthcare providers and experiences of people with mental illness who are service users in those facilities. Such research is necessary ac...
Article
Introduction: Treatment resistant schizophrenia (TRS), affecting approximately one-third of patients with schizophrenia, is associated with a serious impairment in global psychosocial functioning. Clozapine is the only licensed drug for TRS. However its prescription remains limited by its side effects requiring mandatory monitoring. The need to id...
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Background: Bipolar disorder is associated with circadian disruption and a high risk of suicidal behavior. In a previous exploratory study of patients with bipolar I disorder, we found that a history of suicide attempts was associated with differences between winter and summer levels of solar insolation. The purpose of this study was to confirm th...
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Introduction Biological rhythms play an important role in the etiology of mood disorders. Several lines of evidence established a link between circadian rhythm disruption and mood episodes. Chronotypes are the behavioral manifestations of circadian rhythms and eveningness appears to be more frequent in bipolar disorder (BD). The influence of chrono...
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Introduction While the links between cyclothymia and creativity are well documented, the experts have tried to determine whether temperament would influence the major choices of life such as career. Objectives The study aims mainly to evaluate the temperaments of a sample of Tunisian students, and to look for the possible correlations between the...
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Introduction The coronavirus disease 2019 (COVID-19) pandemic created a situation of general distress. Although the focus has been initially more on the physical health during the pandemic, mental health concerns linked to the lockdown have quickly risen. Objectives The aim of this study was to evaluate the impact of the first wave of COVID-19 pan...
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Introduction Electronic cigarettes (e-cigarettes) are battery-powered devices developed with the goal of mimicking the action of smoking. Their use has increased over the past years. Objectives The aim of this study was to evaluate the prevalence of the use of e-cigarettes among teenagers in high school and to examine the predictor factors. Metho...
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Introduction E-cigarette use has increased over the last years. Many studies have examined teenagers’ attitudes towards smoking, but did not examine adolescents’ attitudes towards e-cigarettes. Objectives The aim of this study was to examine high school students’ attitudes regarding e-cigarette safety, addictive properties and social norms and to...
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Introduction The outbreak of the Covid-19 epidemic in Tunisia has led a total confinement startingfrom March 23rd, 2020. Remote interventions of psychiatrists and psychologists have been set up to help tunisiancitizens. The requestsconcerned panic attacks, acute stress disorder, sleepdisorders and relapse of some patients followed for mooddisorders...
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Introduction Violence against women is a public health problem worldwide. During humanitarian crises such as wars, violence expands mainly to the detriment of the most vulnerable groups. Objectives This study aims to assess the effect of the COVID-19-related lockdown on gender-based violence. Methods This study was conducted using an online surve...
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Introduction Procrastination is a common phenomenon among students, defined by the tendency to delay tasks. Procrastination can have a negative impact not only on academic achievement but also on other areas of life. Objectives To assess students’ level of procrastination and associated psychological factors Methods We conducted a cross-sectional...
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Introduction The regulation of emotions is a psychological process covering the capacity of inhibiting, maintaining or modulating emotions to create a coherent psychological functioning and to enable the individual to live in adequacy with his or her environment. Objectives The aim of the study was to develop an Arabic version of the “Regulation o...
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Introduction Due to COVID-19 pandemic, the Tunisian government officially announced a lockdown on March 2020. This decision caused a significant change in the everyday life of Tunisians such as movement restriction revealing the psychosocial aspect of this crisis. Objectives This study aims to assess the impact of the COVID-19 pandemic on the ment...
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The coronavirus disease 2019 (COVID-19) pandemic created a situation of general distress. Although the focus has been initially more on the physical health during the pandemic, mental health concerns linked to the lockdown have quickly risen. This study aims to assess the effect of the COVID-19-related lockdown on Tunisian women’s mental health and...
Article
Background: Depression is a major burden for the health-care system worldwide. It is important to use standardized and easily applicable tools for large-scale population screening to improve the early detection of depression. The PHQ-9 has been recommended as the best available screening and case-finding instrument based on its brevity and ability...
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Suicide is a public health problem affecting majority of patients with psychiatric diseases, including bipolar disorder (BD). The purpose of this study was to estimate the prevalence of suicide attempts (SAs) and to identify different factors associated with it in a population of patients with bipolar disorder type I (BD I). We conducted a cross-se...
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Neuropsychiatric manifestations in Sjögren’s syndrome are common and can occur not only during its course, but also at the onset of the disease. Depression and anxiety were the most frequently described symptoms. However, the association with bipolar disorder seems to be rare and not well documented. This case report presents a patient with bipolar...
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Background The perception by mental health service staff of respect for users' rights is a fundamental component of organizational well-being. The objective of this work is to examine how cultural differences and the working context can influence the perception of respect for users' rights in mental health professionals in the Mediterranean area....
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Background: The perception by mental health service staff of respect for users' rights is a fundamental component of organizational well-being. The objective of this work is to examine how cultural differences and the working context can influence the perception of respect for users' rights in mental health professionals in the Mediterranean area....
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Background The Mood Disorder Questionnaire (MDQ) is a frequently used screening tool for the early detection of Bipolar Disorder (BD), which is often unrecognized or misdiagnosed at its onset. In this study, data from Tunisia has been used to evaluate the psychometric properties of the Arabic MDQ. Methods The sample included 151 patients with a cu...
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Background The Well-Being at Work and Respect for human Rights Questionnaire (WWRR) was conceived based on the hypothesis that the perception of respect for users' rights is an essential element of well-being in the workplace in healthcare. The objective of the study is to examine the principal components of the WWRR. Methods A random sample repre...
Article
In order to manage the urgent psychological need for support in response to the anticipated reaction of the population to the COVID-19 pandemic, we developed a new psychological crisis intervention model by implementing a centralised psychological support system for all of Tunisia. We set up a helpline which is accessible throughout the country, in...
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Introduction: Schizophrenia, bipolar disorder and schizoaffective disorders are severe mental illnesses (SMI) associated with high levels of co-morbid psychopathology and premature mortality. Reducing delays in accessing services and providing early intervention are key strategies in preventing morbidity and mortality associated with these disease...
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Background: Vaginismus affects up to 1% of the female population and often represents a physical manifestation of an underlying psychological problem. Our objective was to investigate the psychosomatic impact of vaginismus in pregnant women and evaluate the quality of their therapeutic care in Tunisia. Methods: We included pregnant patients with...
Chapter
This chapter provides an overview of the current situation and the challenges Tunisia faces in the field of dementia care. Tunisia is a country in full demographic transition, witnessing an ageing of its population and an increase in dementia incidence and prevalence. There is growing awareness that the healthcare system needs to be better oriented...
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Vaginismus in one of the most frequent causes of non-consummation of marriage, and of infertility, in Arab-Muslim societies. Cognitive behavioural therapy (CBT) proved to be effective, but it is important to consider the cultural context of the patient attending CBT for vaginismus. The aim of our study was therefore to draw attention to the belief...
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Objective To confirm prior findings that the larger the maximum monthly increase in solar insolation in springtime, the younger the age of onset of bipolar disorder. Method Data were collected from 5536 patients at 50 sites in 32 countries on six continents. Onset occurred at 456 locations in 57 countries. Variables included solar insolation, birth...
Article
Introduction Co-morbid obsessive-compulsive disorder (OCD) in bipolar disorder (BD) negatively affects clinical course and outcome, and considerably complicates its treatment. Objective To show a therapeutic approach still rarely used in case of resistant bipolar disorder associated with OCD. Methods Presentation of the clinical case of Mr. M.H.,...
Article
Introduction Psychiatric disorders frequently occur in patients with temporal lobe epilepsy (TLE) (70%). This combination further reduces the quality of life of patients as diagnosis is difficult and therapeutic opportunities are often missed. Objectives The aim of this case study is to show the possible association between TLE and psychiatric sem...
Article
Introduction The PHQ-9 has been recommended as the best available screening and case-finding instrument for primary care based on its brevity, and ability to inform the clinicians on both depression severity and diagnostic criteria. Objective Our study evaluated the reliability and the validity of the Tunisian version of the PHQ-9 in detecting maj...
Article
Introduction Dyspareunia is defined as persistent or recurrent genital pain that occurs just before, during or after intercourse. Dyspareunia after childbirth is quite common and have a range of repercussions to women's lives, including their sexual functioning. It could be affected by different risk factors. While role of obstetric factors includi...
Article
Introduction Schizophrenia is a disabling, chronic psychiatric disorder that has far-reaching consequences for both patients and their relatives. Management of schizophrenia involves family support and care. In this context, burden of care is a concept related to caregivers and family's members of patients assuming responsibility for these patients...
Article
Introduction Tardive syndromes (TS) resulting from prolonged exposure to dopamine receptor blocking agents are frequent. Clozapine is considered to have a low risk of causing new onset TS and accounts therefore as an interesting option in patients with invalidating TS. Objectives Our study aims to describe clozapine indications in patients experie...
Article
Introduction Akathisia is probably the most common and one of the most distressing of the movement disorders associated with antipsychotic drugs. Little is known about its prevalence and its risk factors in real-world psychotic and bipolar patients to date. Objectives The main objective of this study was to determine the prevalence of akathisia an...
Article
Introduction Akathisia is commonly known for its objective components such as rocking while standing or sitting and lifting feet. However, little is known about its psychiatric impact that can even lead to suicidal attempts. Objectives The aim of this study is to investigate the main psychiatric symptoms associated with akathisia in a Tunisian sam...
Article
Introduction: Depression is considered a global public health problem especially in the developed countries, where depression is the leading cause of morbidity. Objectives: To determine the point prevalence and the severity of depression in primary health care, to define the profile of patients suffering from depression and consulting in primary...
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Introduction: The experience of psychosis or related treatment can be conceptualized as a traumatic event, which might lead to posttraumatic stress disorder (PTSD) or PTSD syndrome (which is defined as the presence of PTSD symptoms irrespective of the DSM-IV criterion A definition of a traumatic event as an actual or threatened harm). Few studies...
Article
La qualité de vie d’une personne handicapée dépend certainement du degré d’incapacité, mais les facteurs environnementaux, sociaux et économiques jouent un rôle fondamental indépendamment de la sévérité du handicap. Le but de ce travail est de déterminer les différents paramètres objectifs qui interviennent sur la qualité de vie auprès d’un échanti...
Article
Background Mortality in patients in psychiatric hospitals is reported to be two to three times as high as in the general population. In Tunisia, we do not have any figures on mortality and causes of death in psychiatric inpatients. Aim The aim of our study was to assess the mortality rate in a psychiatric hospital in comparison to the mortality ra...
Article
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Mortality in patients in psychiatric hospitals is reported to be two to three times as high as in the general population. In Tunisia, we do not have any figures on mortality and causes of death in psychiatric inpatients.
Article
Every death at a psychiatric hospital raises questions about its cause and the forensic responsibilities it engages.Objectives-To assess the rate of deaths posing forensic problems at a psychiatric hospital.-To determine the patients’ victimological profile.-To identify the causes and risk factors of these deaths.Methods We conducted a retrospectiv...
Article
During the Tunisian Revolution, health professionals at several emergency departments (ED) in Tunis faced difficult situations characterized by an extremely high throughput of patients who also suffered unusual lesions (gunshot wounds). Facing the omnipresent death during the bloodiest periods of the Revolution did definitely leave its traces on he...
Article
The concept of treatment-resistant schizophrenia can be understood in two ways:1)as the persistence of schizophrenic symptoms in a patient taking a medication supposed to be efficient or2)as inefficiency of treatments available for certain forms of schizophrenia such as the early-onset form.Objective To study the relationship between early onset of...
Article
Background: In Tunisia, with the remarkable progress in health, life expectancy has significantly increased these last decades. Indeed, in 2004, 9.3% of the population was aged over 60, and this rate is predicted to reach 17% in 2029 and about 29% by 2050. In the elderly, chronic subdural hematoma (HSDC) may be caused by even minimal trauma or occ...

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precise the role of mindfulness in the treatment of the PTSD, we use MBCT program with some some modifications / the aim oh the study is to evaluate the role of MBCT in the treatment of PTSD