Yoshie Adriana Hata Uribe

Yoshie Adriana Hata Uribe
National University of Colombia | UNAL · Departamento de Farmacia (Bogotá)

Pharmacist, MSc, PhD

About

18
Publications
4,285
Reads
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394
Citations
Introduction
Additional affiliations
October 2009 - present
University of Basel
Description
  • PhD Student
April 2007 - September 2015
National University of Colombia
Position
  • Auxiliary Professor
March 2004 - present
National University of Colombia
Position
  • Research Assistant
Description
  • Teaching assistant in lab practices for pharmacist (phytochemistry). Lecturer.
Education
October 2009 - May 2014
University of Basel
Field of study
  • Pharmaceutical Sciences
February 2003 - July 2005
National University of Colombia
Field of study
  • Pharmaceutical Sciences
February 1993 - April 2000
National University of Colombia
Field of study
  • Pharmacy

Publications

Publications (18)
Article
Magnetic fields (MFs) have been used as an external stimulus to increase cell proliferation in chondrocytes and extracellular matrix (ECM) synthesis of articular cartilage. However, previously published studies have not shown that MFs are homogeneous through cell culture systems. In addition, variables such as stimulation times and MF intensities h...
Article
The growth plate is a cartilaginous layer present from the gestation period until the end of puberty where it ossifies joining diaphysis and epiphysis. During this period several endocrine, autocrine, and paracrine processes within the growth plate are carried out by chondrocytes; therefore, a disruption in cellular functions may lead to pathologie...
Article
Full-text available
Long bone formation starts early during embryonic development through a process known as endochondral ossification. This is a highly regulated mechanism that involves several mechanical and biochemical factors. Because long bone development is an extremely complex process, it is unclear how biochemical regulation is affected when dynamic loads are...
Article
Objective: Hyaline cartilage degenerative pathologies induce morphologic and biomechanical changes resulting in cartilage tissue damage. In pursuit of therapeutic options, electrical and mechanical stimulation have been proposed for improving tissue engineering approaches for cartilage repair. The purpose of this review was to highlight the effect...
Article
In an in vitro screen of 206 extracts from South African plants, the CH2Cl2/MeOH (1:1) stem extract of Drypetes gerrardii Hutch. var gerrardii (Putranjivaceae) inhibited Plasmodium falciparum and Leishmania donovani (IC50s of 0.50 and 7.31 μg/ml, respectively). In addition, the CH2Cl2/MeOH (1:1) extract of the leaves showed activity against Trypano...
Article
Two hundred and seven extracts were prepared from sixty plants from South Africa and screened for in vitro activity against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, and Plasmodium falciparum. For the 21 extracts which inhibited the growth of one or more parasites with more than 95 % at 10 µg/mL, the IC50 values agains...
Article
Full-text available
A library of 206 extracts from selected South African plants was screened in vitro against a panel of protozoan parasites, Plasmodium falciparum, Trypanosoma brucei rhodesiense, and Leishmania donovani. A CH2Cl2/MeOH (1 : 1) extract of Abrus precatorius L. ssp. africanus strongly inhibited P. falciparum (98 %), T. b. rhodesiense (100 %), and L. don...
Article
Human African trypanosomiasis is a neglected tropical disease in sub Saharan Africa that is fatal if left untreated. In a search for new natural products with anti-trypanosomal activity, we recently identified abruquinones B and I from Abrus precatorius as potent in vitro trypanocidal compounds with high selectivity indices. To obtain sufficient co...
Article
In a screen of 1800 plant and fungal extracts for antiplasmodial, antitrypanosomal, and leishmanicidal activity, the n-hexane extract of Chrysanthemum cinerariifolium (Trevir.) Vis. flowers showed strong activity against Plasmodium falciparum. We isolated the five pyrethrins [i.e., pyrethrin II (1), jasmolin II (2), cinerin II (3), pyrethrin I (4),...
Article
In the course of a larger screen of 1800 plant and fungal extracts, the ethyl acetate extract of Saussurea costus roots potently inhibited the growth of Trypanosoma brucei rhodesiense. Subsequent HPLC based activity profiling led to the identification of the sesquiterpene lactones arbusculin B (1), α-cyclocostunolide (2), costunolide (3), and dehyd...
Article
Full-text available
Three hundred extracts were prepared from plants traditionally used in South Africa to treat malaria and screened in vitro for activity against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, and Plasmodium falciparum. For the 43 extracts which inhibited the growth of one or more parasites to more than 95 % at 9.7 µg/mL, the...
Article
In South Africa, Salvia repens is used traditionally to treat sores, stomach ache and diarrhoea. The high performance liquid chromatography (HPLC)-based activity profiling of S. repens whole plant extract showed an active abietane diterpene, identified as 12-methoxycarnosic acid (1) which showed antiprotozoal activity against axenically grown Leish...
Article
In order to improve the knowledge of Colombian flora, particularly that belonging to the llanos orientales region, Strychnos schultesiana Krukoff was chosen for a chemical composition in-depth study to establish a potential utility in medicinal or industrial fields. For this analysis, a preliminary phytochemical study of three organs of the plant -...
Article
Full-text available
Con el fin de ahondar en el conocimiento de la flora colombiana, particularmente aquella presente en la region de los llanos orientales, se eligio la especie Strychnos schultesiana Krukoff para profundizar en su composicion quimica y asi establecer una potencial utilidad medicinal o industrial. Para ello se realizo un analisis fitoquimico prelimina...
Article
Antimalarial activity of 10 vegetal extracts (9 ethanolic extracts and 1 crude alkaloid extract), obtained from eight species traditionally used in Colombia to treat malaria symptoms, was evaluated in culture using Plasmodium falciparum chloroquine resistant (FcB2) strain and in vivo on rodent malaria Plasmodium berghei. The activity on ferriprotop...
Article
Full-text available
Resumen En el presente trabajo presentamos un breve resumen de la problemática asociada a la malaria y los trabajos de screening de plantas con potencial actividad antimalárica. Se presentan los resultados obtenidos con la utilización de un programa de análisis de imágenes de extendidos sanguíneos. El programa ha sido desarrollado para correr autom...

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