Yoram Yovell

• Hebrew University of Jerusalem

As Louis Sander understood, human infants are evolutionarily endowed with emotional minds that allow them to experience themselves as affectively vibrant creatures, who seek to be recognized as important players in the world. If so recognized, they experience themselves as positive individuals; if merely neglected as predetermined beings whose affe...

Background: Evidence points toward shared characteristics between female survivors of sexual abuse and women with dyspareunia. This study explored, for the first time, similarities and differences between women who were exposed to sexual abuse to those with dyspareunia, in order to examine whether insecure attachment styles and high somatization l...

In light of recent neuroscientific findings relevant to psychoanalytic theories about drive and love, Yovell addresses two interrelated and partially overlapping questions: What can the neurosciences contribute to a psychoanalytic understanding of drive? And what can they contribute to a psychoanalytic understanding of how romantic love, sexuality...

Objective: Suicidal ideation and behavior currently have no quick-acting pharmacological treatments that are suitable for independent outpatient use. Suicidality is linked to mental pain, which is modulated by the separation distress system through endogenous opioids. The authors tested the efficacy and safety of very low dosages of sublingual bup...

Los avances recientes en la neurociencia cognitiva, afectiva y social le permitieron a estos campos estudiar los aspectos de la mente que son de fundamental importancia para el psicoanálisis. Estos avances abren una serie de posibilidades para esta disciplina. ¿Puede el psicoanálisis entablar un diálogo productivo y mutuamente enriquecedor con las...

Recent advances in the cognitive, affective and social neurosciences have enabled these fields to study aspects of the mind that are central to psychoanalysis. These developments raise a number of possibilities for psychoanalysis. Can it engage the neurosciences in a productive and mutually enriching dialogue without compromising its own integrity...

Mammalian brains contain at least 7 primal emotional systems - SEEKING, RAGE, FEAR, LUST, CARE, PANIC and PLAY (capitalization reflects a proposed primary-process terminology, to minimize semantic confusions and mereological fallacies). These systems help organisms feel affectively balanced (e.g. euthymic) and unbalanced (e.g. depressive, irritable...

Objectives. This study assessed the interactive effect of two risk factors: "Juvenile stress" and sex in the long-term consequences of "Juvenile stress" in male and female rats. Methods. Rats were exposed to "Juvenile stress" and to additional stress in adulthood. Measurements of anxiety and depressive-like behaviours were assessed in relation to e...

Women with a history of sexual abuse (SA) commonly report greater pain symptoms. It is still unclear whether enhanced pain susceptibility is the result of altered pain processing and response. Therefore, this pilot study aimed to explore pain sensitivity to experimentally induced pain and associated psychology in women with a history of severe SA....

In this study, the authors explored the relations among painful experience during sexual intercourse, attachment style, and somatization. The authors assessed these variables by self-report of dyspareunia (painful vaginal intercourse) and by completion of the Experience in Close Relationships Scale and the short version of the Brief Symptom Invento...

This paper offers a neuropsychoanalytic examination of two partially overlapping issues: the nature of the relationship between romantic love, sexuality, and attachment; and the possible existence of a unique drive for romantic love. Over the last century, Freud’s theories about the mental forces and developmental pathways that lead to adult romant...

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Traumatic amnesia has been amply documented in the psychoanalytic literature but inconsistently in the research literature. Six trauma were followed prospectively. Survivors were interviewed 7, 30, and 120 days following the traumatic event. Each interview documented in detail their recollections of the day of their trauma. In four subjects who did...

When patient and therapist belong to two opposing ethnic groups that are engaged in war and terror, anonymity, neutrality, and indeed psychotherapy itself become almost impossible. Primitive transferences that involve suspicion and hostility are mobilized from the very beginning, and sadomasochistic power struggles threaten the therapeutic alliance...

Memories in general, and memories of trauma in particular, are of extreme importance to psychoanalysis, and have been so for over a hundred years. To this day, traumatic memories are the focus of controversy regarding both theory and technique within the field of psychoanalysis (Hedges, 1994). Over the past few years, they have also become a subjec...

An important recent insight in a number of neurobiological systems is that during learning, individual dually regulated proteins with associative properties function as critical sites of stimulus convergence. During conditioning in Aplysia, the Ca2+ /calmodulin-sensitive adenylyl cyclase (AC) in mechanosensory neurons serves as a molecular site of...

To assess the relationship between two phenotypes in an extremely well-characterized population of personality disorder patients–impulsive aggression and prolactin response to fenfluramine–and tryptophan hydroxylase (TPH) genotype, TPH genotype (at an intronic polymorphic site) and prolactin response to fenfluramine were assessed in 40 Caucasian pa...

To assess the relationship between two phenotypes in an extremely well-characterized population of personality disorder patients–impulsive aggression and prolactin response to fenfluramine–and tryptophan hydroxylase (TPH) genotype, TPH genotype (at an intronic polymorphic site) and prolactin response to fenfluramine were assessed in 40 Caucasian pa...

To assess patterns of hearing loss and asymmetry in major depressive disorder (MDD), pure-tone and brief-click audiometric thresholds were measured in 59 inpatients with MDD and 40 normal control subjects. For both tasks, patients had higher bilateral thresholds, with marked hearing loss for the highest pure-tone frequency. At lower frequencies, pa...

Studies in Aplysia and Drosophila have suggested that Ca2+/calmodulin-sensitive adenylyl cyclase may act as a site of convergence for the cellular representations of the conditioned stimulus (Ca2+ influx) and unconditioned stimulus (facilitatory transmitter) during elementary associative learning. This hypothesis predicts that the rise in intracell...

Cellular experiments have suggested that during classical conditioning of the gill and siphon withdrawal reflex of Aplysia, adenylyl cyclase may serve as a molecular site of convergence for Ca2+ and serotonin (5-hydroxytryptamine; 5-HT), the cellular representations of the conditioned and unconditioned stimuli (CS and US). We explored the possible...

During short-term sensitization, a simple form of nonassociative learning in Aplysia, the presentation of a single brief noxious stimulus results in enhancement of the defensive withdrawal reflex lasting minutes to tens of minutes. This behavioral plasticity involves presynaptic facilitation of synaptic transmission from the mechanosensory neurons...

Two experimental approaches--the cellular and the neurogenetic--to the study of molecular mechanisms of elementary memory implicate the cyclic AMP cascade in general, and adenylate cyclase in particular, in the processes of acquisition and short-term memory. Models of learning and memory should account for four basic phenomena: persistence of memor...

The Drosophila memory mutant rutabaga (rut) has been previously shown to have a defective subpopulation (or functional state) of the enzyme adenylate cyclase. We report here that the reduced adenylate cyclase activity is also associated with a defective responsiveness of the enzyme to forskolin. Forskolin activation isotherms of the enzyme in norma...

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