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Yohan Farouz

Yohan Farouz
Roche · Pharma Research and Early Development (pRED)

Ph.D.

About

9
Publications
24,139
Reads
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426
Citations
Additional affiliations
September 2012 - August 2014
Paris Descartes, CPSC
Position
  • Professor
Description
  • Created a new course of Biomedical Modeling in the Biomedical Engineering Master's programme. The course aims at teaching Matlab programming through projects based on real biological and medical needs.
September 2011 - September 2015
Ecole Normale Supérieure de Paris
Position
  • PhD Student
September 2011 - September 2015
French Institute of Health and Medical Research
Position
  • PhD Student
Education
October 2009 - September 2010
Imperial College London
Field of study
  • Biomedical Engineering
September 2006 - September 2010
Ecole Polytechnique ParisTech
Field of study
  • Biology, Materials Science
September 2004 - June 2006
Lycée Janson de Sailly
Field of study
  • Mathematics, Physics, Chemistry

Publications

Publications (9)
Article
A novel hybrid phage carrying genes from prokaryotic M13 phage and eukaryotic adeno-associated viruses can be used as a tissue engineering material with gene delivery functions. The filamentous shape of the resulting hybrid phage easily forms nanofibrous matrices, which can support cellular growth in tissue culture conditions and deliver the target...
Article
Tissue engineering aims at recapitulating permissive conditions that enable cells to collaborate and form functional tissues. Applications range from human tissue modeling for diagnostic purposes to therapeutic solutions in regenerative medicine and surgery. Across this spectrum, human stem cells are the active ingredient, expandable virtually inde...
Article
Soft hydrogels such as alginate are ideal substrates for building muscle in vitro because they have structural and mechanical properties close to the in vivo extracellular matrix (ECM) network. However, hydrogels are generally not amenable to protein adhesion and patterning. Moreover, muscle structures and their underlying ECM are highly anisotropi...
Article
Retinal cells within neurovascular units generate the blood-retinal barrier (BRB) to regulate the local retinal microenvironment and to limit access to inflammatory cells. Breakdown of the endothelial junctional complexes in the BRB negatively affects neuronal signaling and ultimately causes vision loss. As new therapeutics are being developed eith...
Thesis
Cell therapy is a promising strategy to help regenerate the damaged heart. Recent studies have placed a lot of hopes in embryonic stem cells and our lab had previously found a way to differentiate them into cardiac progenitors, cells that can only differentiate into cardiomyocyte, endothelial cells or smooth muscle cells. This early commitment decr...
Chapter
Full-text available
To get approval for initiating a stem cell clinical trial is becoming increasingly difficult because of the stringency of regulatory guidelines. The first section of this chapter presents an outline of the major issues which should be kept in mind by investigators from the very early onset of the program so as to frame it in such a way that it may...
Article
Background Cardiac-committed cells and biomimetic scaffolds independently improve the therapeutic efficacy of stem cells. This study tested the long-term effects of their combination. Methods and Results Eighty immune-deficient rats underwent permanent coronary artery ligation. Five to 7 weeks thereafter, those with an echocardiographically-measur...
Article
Full-text available
Aim: There is now compelling evidence that cells committed to a cardiac lineage are most effective for improving the function of infarcted hearts. This has been confirmed by our pre-clinical studies entailing transplantation of human embryonic stem cell (hESC)-derived cardiac progenitors in rat and non-human primate models of myocardial infarction...
Article
Type: Review Language: French. Original title: Réparer les coeurs brisés et les vaisseaux abîmés

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