Yogesh Kumar Dwivedi

Yogesh Kumar Dwivedi
B. S. Anangpuria Educational Institutes · Computer Science

B.Tech in Computer Science Engineering
desire to do something extraordinary for cyber technology world.

About

104
Publications
4,552
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Introduction
At this time we are searching on the market policies and changing with the times on the method of marketing the technological features in the market well and delivering them to the customers in the right way. Which is psychologically possible in different and different ways as well. We are also doing more and more data research about the increasing internet employment, Due to which the foundation will be strengthened, research on artificial intelligence machine learning and internet is going on.

Publications

Publications (104)
Article
Vitamin D deficiency is associated with immune dysregulation, increased vulnerability to infections, depression, and suicidal behavior. One mediator of vitamin D-dependent immune regulation and antimicrobial defense is the cathelicidin antimicrobial peptide (LL37), encoded by the cathelicidin-related antimicrobial peptide (CRAMP) gene. We compared...
Article
Increasing evidence incriminates low-grade inflammation in cardiovascular, metabolic diseases, and neuropsychiatric clinical conditions, all important causes of morbidity and mortality. One of the upstream and modifiable precipitants and perpetuators of inflammation is chronic periodontitis, a polymicrobial infection with Porphyromonas gingivalis (...
Article
We report the preparation of 0.1% Eu³⁺; x% Gd³⁺ (0 ≤ x ≤ 1.2) ZnAl2O4 phosphors using the citrate sol–gel method. X-ray diffraction (XRD) data revealed that all annealed samples consisted of the single phase of cubic ZnAl2O4 structure. The scanning electron microscopic (SEM) images indicated pronounced effect of dual doping on the surface morpholog...
Article
Full-text available
Childhood environment can have a profound impact on brain structure and function. Epigenetic mechanisms have been shown to play a critical role in adaptive and maladaptive processes by regulating gene expression without changing the genome. Over the past few years, early life stress (ELS) has been established as a major risk factor for major depres...
Article
Background: Major Depressive Disorder (MDD) is a leading cause of mental disability worldwide. Despite many studies, the pathophysiology associated with MDD brain is not very clear. It is reported that cellular stress is related to depressive symptoms. Under stressful conditions, intracellular homeostasis processes can be disrupted, which can indu...
Book
This book constitutes the refereed proceedings of the IFIP WG 8.6 International Working Conference "ICT Unbounded, Social Impact of Bright ICT Adoption" on Transfer and Diffusion of IT, TDIT 2019, held in Accra, Ghana, in June 2019. The 30 revised full papers and 4 short papers presented were carefully reviewed and selected from 72 submissions. Th...
Article
Suicide is a major public health concern. A significant proportion of depressed individuals show suicidal ideation. The currently available medications are not optimal and a large number of depressed/suicidal patients do not respond to these medications. Thus, there is an urgent need to fully understand the neurobiological mechanisms associated wit...
Article
Introduction: Dexmedetomidine provides stable perioperative hemodynamic profile with decreased requirement of opioids. It has neuroprotective effect and may be suitable anesthetic adjuvant when compared to fentanyl. The main aim of our study was to compare dexmedetomidine and fentanyl in relation to blunting of sympathetic response to intubation an...
Article
Full-text available
Worldwide, suicide is a leading cause of death. While a sizable proportion of deaths by suicide may be preventable, it is well documented that despite major governmental and international investments in research, education and clinical practice suicide rates have not diminished and are even increasing among several at-risk populations. While nonhum...
Article
Full-text available
Worldwide, suicide is a leading cause of death. Although a sizable proportion of deaths by suicide may be preventable, it is well documented that despite major governmental and international investments in research, education and clinical practice suicide rates have not diminished and are even increasing among several at-risk populations. Although...
Article
Introduction Suicide is a leading cause of death. Although research on the biological aspects of suicide is accumulating, there is no testable biomarker to assess suicidality. miRNAs, small non-coding RNAs, have been implicated in synaptic plasticity, genetic susceptibility to stress and coping to stress response. Because of the presence of microRN...
Article
Objectives: Recent evidences suggest that mitochondrial dysfunction maybe involved in the pathophysiology of major depressive disorder (MDD); however, the role of mitochondrial genes in this disorder has not been studied systematically. In the present study, we profiled expression of mitochondrial genes in dorsolateral prefrontal cortex (dlPFC) of...
Article
Central infusion of the Na+/K+-ATPase inhibitor, ouabain in rats serves as an animal model of mania because it leads to hyperactivity, as well as reproduces ion dysregulation and reduced BDNF levels similar to that observed in bipolar disorder. Bipolar disorder is also associated with cognitive inflexibility and working memory deficits. It is unkno...
Chapter
Major affective disorders are common conditions associated with relevant disability, psychosocial impairment, and suicidal behavior. Both affective disorders and suicidal behavior have been associated with impairments in synaptic plasticity and cellular resilience. It has been suggested that small noncoding RNAs, especially microRNAs (miRNAs) may b...
Article
Suicide is a major public concern. About one million people commit suicide every year worldwide. In the teenage population, it is the third leading cause of death in the USA. Although the underlying pathophysiology of suicide is not very well understood, postmortem brain studies have provided a greater understanding of the neurobiological abnormali...
Article
Edge detection is the common approach used in segmentation in image processing. In an image, edge can be the boundary between two regions with relatively distinct grey level properties. Image processing is a sequence of operations which are applied to the images to enhance, alter the select regions of interest called segmentation. In this paper, su...
Article
This paper report the structural and spectroscopic properties of BaTiO3 nanosized phosphor activated with Ho3+and Yb3+ ions. Samples were prepared using solid state reaction method. XRD techniques have been used for the phase characterizations. The phosphor contains nanocrystallites with average size of ∼65 nm. Optical properties of the synthesized...
Article
Full-text available
In this paper, we examine the combined effects of thermal radiation, buoyancy force and magnetic field on oscillatory flow of a conducting optically thin dusty fluid through a vertical channel filled with a saturated porous medium. The governing partial differential equations are obtained and solved analytically by variable separable method. Numeri...
Chapter
Major depressive disorder (MDD) is a major public health concern. Although much work has been done to characterize MDD, a large number of MDD patients do not respond to the currently available medications and the relapse rate for depression is quite high. Thus, there is an urgent need to fully understand the neurobiological abnormalities associated...
Article
The laser‐induced crystallization method was applied to pattern β‐BaB2O4 crystals (β‐BBO) in the inside of bulk glass plate and fibers of 8Sm2O3–42BaO–50B2O3, in which the focal position of continuous wave (CW) Yb:YVO4 fiber lasers (power: 0.9–1.0 W, scanning speed: 2 μm/s) with a wavelength of 1080 nm was moved gradually from the surface to the in...
Article
The paper investigates the effects of heat transfer in MHD flow of viscoelastic stratified fluid in porous medium on a parallel plate channel inclined at an angle θ. A laminar convection flow for incompressible conducting fluid is considered. It is assumed that the plates are kept at different temperatures which decay with time. The partial differe...
Article
The present note deals with the effects of radiative heat transfer and free convection in MHD for a flow of an electrically conducting, incompressible, dusty viscous fluid past an impulsively started vertical non-conducting plate, under the influence of transversely applied magnetic field. The heat due to viscous dissipation and induced magnetic fi...
Article
Full-text available
An analytical study of effect of heat source on MHD blood flow through bifurcated arteries has been done. The blood flowing through arteries is treated to be unsteady Newtonian flow. The coupled linear partial differential equations are solved by converting into ordinary linear differential equations by choosing the axial velocity, normal velocity...
Article
Full-text available
The present paper is concerned with the study of MHD free convective flow of a visco-elastic (Kuvshinski type) dusty gas through a porous medium induced by the motion of a semi-infinite flat plate under the influence of radiative heat transfer moving with velocity decreasing exponentially with time. The expressions for velocity distribution of a du...
Article
We consider a zero mean discrete time series, and define its discrete Fourier transform (DFT) at the canonical frequencies. It can be shown that the DFT is asymptotically uncorrelated at the canonical frequencies if and only if the time series is second?order stationary. Exploiting this important property, we construct a Portmanteau type test stati...
Article
Full-text available
The present paper is concerned with the study of MHD free convective flow of a visco-elastic (Kuvshinski type) dusty gas through a porous medium induced by the motion of a semi-infinite flat plate under the influence of radiative heat transfer moving with velocity decreasing exponentially with time. The expressions for velocity distribution of a du...
Article
cAMP-specific PDE4 are a family of enzymes capable of hydrolyzing cAMP to 5’AMP. cAMP plays a major role in synaptic plasticity, neurite outgrowth, and neuronal differentiation and survival and recent studies demonstrate involvement of cAMP in pathophysiology of depression. The cAMP-specific PDE4 can be differentiated from other PDE families by seq...
Chapter
The widespread domestic use of broadband Internet technology has been recognized to have a positive influence on national economies and improve the life of citizens. Despite substantial investment to develop the infrastructure, many countries have experienced slow adoption rates for broadband. This chapter develops a view of UK broadband adoption u...
Chapter
The widespread domestic use of broadband Internet technology has been recognized to have a positive influence on national economies and improve the life of citizens. Despite substantial investment to develop the infrastructure, many countries have experienced slow adoption rates for broadband. This chapter develops a view of UK broadband adoption u...
Chapter
The previous chapters (Chapters 4 and 5) described the development and validation of a survey instrument for the purpose of data collection in order to examine broadband adoption, usage, and impact. Chapter 3 provided a discussion and justification of the data collection and analysis methods. This chapter presents the findings obtained from the sur...
Chapter
Broadband potentially has benefits for education, but in order to be beneficial it has to be used. In this chapter, we have investigated from a user perspective: (1) to what extent broadband is used in Dutch education (in the classroom as well as in the organisation as a whole); (2) the experiences teachers have with broadband, including impediment...
Chapter
This chapter empirically examines factors affecting the adoption of broadband in the developing countries of Bangladesh and the Kingdom of Saudi Arabia (KSA). In the case of Bangladesh, attitudinal, normative, and control factors—discussed in the UK case study in Division I of this book—were used and adapted in order to provide insights about broad...
Chapter
The previous chapter formed a conceptual model aimed at examining broadband adoption, usage, and impact from the context of household consumers. This chapter aims to provide an overview of the research approaches utilised within information systems (IS) field, which leads to the selection of an appropriate research approach for guiding the validati...
Chapter
Chapter 2 described the proposed conceptual model that is used to understand the adoption, usage, and impact of broadband from the consumer perspective. Chapter 3 described the appropriate research approach for testing the hypotheses and to validate the proposed conceptual model. From Chapter 3 it was concluded that the survey research approach is...
Chapter
The previous chapter (Chapter 4) described the development and validation of a survey instrument for the purpose of data collection in order to examine broadband adoption, usage and impact. Chapter 3 provided a discussion and justification of the data collection and analysis methods. This chapter presents the findings obtained from a nationwide sur...
Chapter
This chapter provides a conclusion of the results and discussions of the UK case study research presented in this book. The chapter begins with an overview of this research in the next section. This is followed by the main conclusions drawn from this research. Following this, a discussion of the research contributions and implications of this resea...
Chapter
The penetration of the Internet and opportunities involving information and communication technologies (ICTs) have occurred at an escalating rate within the private sector. This has caused governments and public sector organisations around the globe to become aware of their potential and consequently utilise them; thereby triggering investments in...
Chapter
An examination of previous literature in the information systems (IS) area illustrates that researchers have not yet undertaken research on broadband in the area of consumer diffusion, including the adoption, usage, and impact in the household (Crabtree, 2003; Oh et al., 2003; Stanton, 2004). Instead, most of the research associated with broadband...
Chapter
The previous chapters (Chapters 6 and 7) presented the findings obtained from the survey conducted to examine the adoption, usage, and impact of broadband in UK households. The purpose of this chapter is to discuss and reflect upon the findings from a theoretical perspective using those presented in Chapter 2. It also discusses the empirical issues...
Chapter
Broadband is a technology still penetrating the telecommunication market and is seen as the most significant evolutionary step since the emergence of the Internet. However we argue that in the rush to achieve market share, insufficient attention has been paid to quality issues, the central theme of this chapter. Indeed, the concept of quality is a...
Chapter
This chapter presents the implications of the research discussed in this book and outlines future research trends in the area of consumer adoption and usage of broadband. The findings of the studies detailed in this book generate a number of implications that may be relevant to policy makers, Internet service providers (ISPs), and other relevant st...
Chapter
The Netherlands has experienced a high uptake of broadband Internet amongst its population. However, the question remains whether there are any differences between people with a broadband connection to people with a narrowband connection. The central research question in this chapter is therefore: how do Dutch internet users with a broadband connec...
Chapter
The previous chapter (Chapter 6) examined the differential usage of the Internet in broadband and narrowband environments. However, the previous chapter excluded the comparison of current and future consumer use of various electronic services and applications at home and in the work place in the UK. A recently published report that was submitted to...
Chapter
This chapter provides an introduction to this research monograph. The following section provides a definition of broadband, outlines broadband’s potential, and then provides a discussion of the research problem comprising the focus of this book. Following that, a discussion of the state of broadband adoption, usage, and impact is presented. This is...
Article
In modern society, suicide is a major public health problem, yet currently the neurobiologic risk factors associated with suicide are still poorly understood. Recent studies demonstrate that alteration in synaptic and structural plasticity is key to affective disorders and suicide. Signal transduction molecules play an important role in such plasti...
Article
Earlier studies have implicated brain-derived neurotrophic factor in stress and in the mechanism of action of antidepressants. It has been shown that antidepressants upregulate, whereas corticosterone downregulates, brain-derived neurotrophic factor expression in rat brain. Whether various classes of antidepressants reverse corticosterone-mediated...
Article
Full-text available
The Raf kinases Raf-1 and B-Raf are upstream activators of the extracellular signal-regulated kinase (ERK)-signaling pathway and therefore participates in many physiological functions in brain, including neuronal survival and synaptic plasticity. Previously, we observed that activation of ERK-1/2, the downstream component of ERK signaling, is signi...
Conference Paper
Full-text available
Neuroscience 2004 Abstract Presentation Number: 354.7 Abstract Title: Antidepressant effects on HPA axis-mediated changes in protein kinase A in rat brain. Major depression is frequently associated with hyperactive hypothalamic-pituitary-adrenal (HPA) axis. Clinically effective therapy with antidepressants normalizes the disturbed HPA activity. The...
Article
In order to examine whether antidepressants mediate their action by interacting with one of the key components of the phosphoinositide (PI) signaling pathway, i.e. PI-specific phospholipase C (PLC), and whether this represents a common mechanism of action of antidepressants, we determined the effects of antidepressants of various classes on PI-PLC...
Article
lipoxygenase (5LOX) is the key enzyme in the synthesis of leukotrienes from arachidonic acid. Hyperglucocorticoidemia, dexamethasone, and aging up-regulate 5LOX in the brain, including the cerebellum in vivo. We studied the mechanisms of dexamethasone-triggered 5LOX up- regulation in primary cultures of rat cerebellar granule neurons (CGN). We meas...
Article
The extracellular regulated kinases (ERK) 1 and ERK2 are members of mitogen-activated protein (MAP) kinase family that play an important role in transducing extracellular signals to the nucleus and have been implicated in a broad spectrum of biological responses. To test the hypothesis that MAP kinases may be involved in depression, we examined the...
Article
The hypothalamic-pituitary-adrenal (HPA) axis has been shown to be involved in mood and behavior. The possibility that adrenal glucocorticoids regulate components of the phosphatidylinositol (PI) signal transduction pathway was investigated. Two different doses of corticosterone (CORT) pellets (50 or 100 mg) were implanted in normal and bilaterally...
Article
Alterations in hypothalamic-pituitary-adrenal (HPA) function are associated with changes in mood and behavior. Protein kinase A (PKA), on activation, phosphorylates many important intracellular proteins and thereby plays a major role in mediating various physiological functions in brain. We systematically examined the relationship of altered HPA fu...
Article
Alterations in hypothalamic-pituitary-adrenal (HPA) function are associated with changes in mood and behavior. Protein kinase A (PKA), on activation, phosphorylates many important intracellular proteins and thereby plays a major role in mediating various physiological functions in brain. We systematically examined the relationship of altered HPA fu...
Article
The enzyme phosphoinositide-specific phospholipase C (PI-PLC) is a component of the phosphoinositide signal transduction system. Other components of this system have been found to be abnormal in adults and adolescents who have committed suicide, and so the authors examined whether PI-PLC activity and protein expression of PLC isozymes are abnormal...
Article
In the brain, the expression of 5-lipoxygenase (5-LO), the enzyme responsible for the synthesis of inflammatory leukotrienes, increases during aging. Antiinflammatory drugs are currently being evaluated for the treatment of aging-associated neurodegenerative diseases such as Alzheimer's disease. Although generally considered antiinflammatory, gluco...
Article
Altered hypothalamic-pituitary-adrenal (HPA) function has been shown to be associated with changes in mood and behavior. The enzyme phosphoinositide-specific phospholipase C (PI-PLC), an important component of the PI signal transduction system, plays a major role in mediating various physiological functions. In the present study, we investigated th...
Article
Altered hypothalamic-pituitary-adrenal (HPA) function (increased plasma cortisol level) has been shown to be associated with mood and behavior. Protein kinase C (PKC), an important component of the phosphatidyl-inositol signal transduction system, plays a major role in mediating various physiological functions. The present study investigates the ef...
Article
Full-text available
Postmortem prefrontal cortices (PFC) (Brodmann's areas 10 and 46), temporal cortices (Brodmann's area 22), hippocampi, caudate nuclei, and cerebella of schizophrenia patients and their matched nonpsychiatric subjects were compared for reelin (RELN) mRNA and reelin (RELN) protein content. In all of the brain areas studied, RELN and its mRNA were sig...
Article
The aim of this study was to examine the effects of subchronic administration of psychoactive drugs on the alpha subunits of G proteins in the rat brain, and also to determine if different classes of psychoactive drugs share a common property, i.e., of altering levels of these proteins. For this purpose, we selected the psychoactive drugs desiprami...
Article
There is evidence indicating that Ins 1,4,5-trisphosphate receptors (IP3R) are involved in the pathophysiology of abnormal brain function. A decreased number of IP3R in the brain of patients with Alzheimer's disease or olivopontocerebellar atrophy have been reported; however, the role of IP5R in the platelets of persons with these and other mental...
Article
Abnormalities in the serotonergic system have been implicated in suicidal behavior. Higher numbers of serotonin-2 (5-HT2) receptors have been reported in the post-mortem brain of suicide victims. In order to further examine the role of 5-HT2A receptors in suicidal behavior, the authors studied 5-HT2A receptors in platelets of suicidal and nonsuicid...
Article
Perfusion of liver of rats toxicated with galactosamine or thioacetamide with a 0.02% solution of picroliv (glycoside fraction of Picrorhiza kurroa) for 30 min (1 ml/min; 6 mg/rat), significantly reversed toxicant-induced changes in the activities of several enzymes. Galactosamine induced increases in the activities of alkaline phosphatase, gamma-g...
Article
The hepatoprotective activity of Picroliv, a standardized iridoid glycoside fraction of Picrorhiza kurroa, has been investigated by studying the protection of biochemical and histological changes induced in livers of rats given single oral doses (7 mg/kg) of aflatoxin B1. Administration of aflatoxin B1 resulted in a significant increase in 5'-nucle...
Article
D-Galactosamine (800 mg/kg, intraperitoneally) caused significant decrease in the activities of 5'-nucleotidase, glucose-6-phosphatase and cytochrome P450 and increase in activities of gamma-glutamyl transpeptidase, succinate dehydrogenase, acid phosphatase and acid ribonuclease in liver after 24 hr. The levels of RNA, protein and glycogen decrease...
Article
The efficacy of Picroliv, a standardized iridoid glycoside fraction of Picrorhiza kurroa, was studied against the Amanita phalloides-induced biochemical changes in rat liver. A phalloides (50 mg.kg-1) caused significant increases in the activities of hepatic 5'-nucleotidase, gamma-glutamyl transpeptidase, acid ribonuclease, and succinate dehydrogen...

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