Yoav Kan-Tor

Hebrew University of Jerusalem | HUJI · Leibnitz Center for Research in Computer Science

The application of deep learning methods, particularly foundation models, in biological research has surged in recent years. These models can be text-based or trained on underlying biological data, especially omics data of various types. However, comparing the performance of these models consistently has proven to be a challenge due to differences...

Purpose To compare two different datasets, using Eyetemis, an online analytical tool designed for assessing the spherical equivalent prediction errors (SEQ-PE) of intraocular lens (IOL) power calculation formulas following cataract surgery. Setting Institutional. Design Retrospective case series. Methods The study was comprised of two distinct d...

In IVF treatments, extended culture to single blastocyst transfer is the recommended protocol over cleavage-stage transfer. However, evidence-based criteria for assessing the heterogeneous implications on implantation outcomes are lacking. The purpose of this work is to estimate the causal effect of blastocyst transfer on implantation outcome. We f...

In IVF treatments, accurate assessment of the developmental potential of embryos to implant is essential for reaching reasonable pregnancy rates while shortening time-to-pregnancy. Hence, clinical guidelines recommend extended incubation to blastocyst transfers, which provide better evaluation of embryo developmental potential. However, cleavage st...

Purpose Our objective was to design an automated deep learning model that extracts the morphokinetic events of embryos that were recorded by time-lapse incubators. Using automated annotation, we set out to characterize the temporal heterogeneity of preimplantation development across a large number of embryos. Methods To perform a retrospective stu...

Resilin is an elastic rubber‐like protein found in the cuticles of insects. It incorporates outstanding properties of high resilience and fatigue lifetime, where kinetic energy storage is needed for biological functions such as flight and jumps. Since resilin is rich in tyrosine groups, localized photopolymerization is enabled due to the ability to...

How are children affected when states prohibit child welfare agencies from discriminating against same‐sex couples who wish to foster or adopt? This question stands at the heart of a debate between governments that seek to impose such antidiscrimination requirements and child welfare agencies that challenge them on religious freedom grounds. Yet un...

Purpose First trimester miscarriage is a major concern in IVF-ET treatments, accounting for one out of nine clinical pregnancies and for up to one out of three recognized pregnancies. To develop a machine learning classifier for predicting the risk of cleavage-stage embryos to undergo first trimester miscarriage based on time-lapse images of preimp...

Study question Decision of how many and which embryos to transfer in each cycle is determined by multiple factors, and the integration of patient-specific considerations is challenging. Summary answer We developed an embryo transfer strategy support tool (ET-SST) that finds the optimal way to conduct the embryo transfer process. What is known alr...

The majority of human embryos, whether naturally or in vitro fertilized (IVF), do not poses the capacity to implant within the uterus and reach live birth. Hence, selecting the embryos with the highest developmental potential to implant is imperative for improving pregnancy rates without prolonging time to pregnancy. The developmental potential of...

Purpose : To compare standard and total corneal astigmatism measurements to the predicted pseudophakic (non-toric) refractive astigmatism in candidates for cataract surgery. Design : A retrospective, cross-sectional study. Methods : A single-center analysis of consecutive eyes measured with an SS-OCT biometer at a large tertiary medical center be...

This article addresses the gap between normative expectations of the right to protest in liberal democracies and the continued practice of repressive protest policing. The empirical literature has identified three types of factors explaining repressive policing: macro- or societal-level factors, meso-level factors relating to the police organizatio...

In IVF treatments, extended culture to single blastocyst-transfer is the recommended protocol over cleavage-stage transfer. However, evidence-based criteria for assessing the heterogeneous implications on implantation outcome are lacking. To estimate the causal effect of blastocyst-transfer on implantation outcome, we assembled a multicenter datase...

Monitoring pupillary size and light-reactivity is a key component of the neurologic assessment in comatose patients after stroke or brain trauma. Currently, pupillary evaluation is performed manually at a frequency often too low to ensure timely alert for irreversible brain damage. We present a novel method for monitoring pupillary size and reactiv...

Significance The clinical utility of mesenchymal stromal/stem cells (MSCs) in mediating immunosuppressive effects and supporting regenerative processes is broadly established. However, the inherent heterogeneity of MSCs compromises its biomedical efficacy and reproducibility. To study how cellular variation affects fate decision-making processes, w...

Purpose To assess oocyte quality in young patients with decreased ovarian response to controlled ovarian stimulation using time-lapse analysis. Methods A retrospective cohort study conducted at five medical centers between 2013 and 2017. The “decreased ovarian response” (DOR) group consisted of 241 women who underwent controlled ovarian stimulatio...

Background It is unclear whether sperm origin, either ejaculated or testicular, in couples diagnosed with male factor infertility, affects the timing of the embryo's developmental events evaluated by time‐lapse monitoring and implantation rates. Objective To examine the effect of sperm origin on embryo morphokinetics in couples diagnosed with male...

Objective Develop a machine learning classifier for predicting the risk of cleavage-stage embryos to undergo first trimester miscarriage based on time-lapse images of preimplantation development. Design Retrospective study of a 4-year multi-center cohort of women undergoing intra-cytoplasmatic sperm injection (ICSI). The study included embryos wit...

Mesenchymal stromal/stem cells (MSCs) are a heterogeneous population of multipotent progenitors that contribute to tissue regeneration and homeostasis. MSCs assess extracellular elasticity by probing resistance to applied forces via adhesion, cytoskeletal, and nuclear mechanotransducers, that direct differentiation toward soft or stiff tissue linea...

In in vitro fertilization (IVF) treatments, early identification of embryos with high implantation potential is required for shortening time to pregnancy while avoiding clinical complications to the newborn and the mother caused by multiple pregnancies. Current classification tools are based on morphological and morphokinetic parameters that are ma...

The ThoraXS has the potential to change the way we treat trauma victims today, ensuring that every chest trauma patient will receive the appropriate treatment in a timely manner, in the field.

Tension pneumothorax is a life-threatening medical emergency mostly associated with chest trauma. It is considered a leading cause of death due to injury and represents a substantial portion of potentially preventable deaths in the battlefield. The accepted therapeutic approach is manual thoracostomy with chest tube insertion. This is a relatively...