Yixin Wang

Yixin Wang
Tsinghua University | TH · Department of Mechanical Engineering

Master of Engineering

About

11
Publications
1,136
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90
Citations

Publications

Publications (11)
Article
Full-text available
Soft actuators with high safety, adaptivity, and energy-to-weight ratio have the potential to be used in developing more adaptive legged robots. In this work, we incorporate soft actuators into rigid parallel mechanisms and develop multi-degree-of-freedom (multi-DOF) soft-rigid hybrid joints that can actively achieve 1, 2, and 3 DOFs actuated by 2,...
Article
Full-text available
Accurate drug delivery to the lesion has been deliberated for several decades, but one important phenomenon is usually neglected that the immune system can prevent smooth transportation of nanomedicine. Although injection would reduce first-pass effect, macrophages in the blood can still recognize and phagocytose nanomedicine. Here we show that a l...
Article
Although advances in coating technologies have allowed us to match—or even exceed—the lubricity of Nature’s low-friction surfaces, the performance of synthetic materials inevitably diminishes over time as the surfaces are worn and damaged by irreversible breakage of covalent bonds. Synthetic systems lack the bespoke repair mechanisms that replenish...
Article
Full-text available
The superlubrication property of articular cartilage is attributed to the hydration lubrication mechanism. This involves the complexation of biomacromolecules with phosphatidylcholine lipids to form a lubricating boundary layer on the surface. Based on this mechanism, a branched polyelectrolyte polymer – PEI‐PMPC was synthesised in this study to en...
Article
A charged polymer brush grafted surface, inspired by natural articular cartilage, achieves an excellent lubricating performance with a low coefficient of friction due to the mechanism of hydration lubrication. The surface charged brush forms a hydration shell which can undergo large normal load without deformation. Additionally, the rapid exchange...
Article
Osteoarthritis (OA) is a chronic joint disease resulting from joint inflammation and damage. In this study, we employed a boundary lubricant known as 1, 2-distearoyl-sn-glycero-3-phosphocholine (DSPC) liposome for loading of an anti-inflammatory drug D-glucosamine sulphate (GAS) to construct a treatment strategy allowing for sustained anti-inflamma...
Article
Natural articular cartilage has excellent superlubrication property, and it is attributed to the hydration lubrication mechanism of the charged biomacromolecules which extend from the cartilage surface to form a brush‐like layer. In this study, a bioinspired brush‐like polyelectrolyte, namely poly(2‐methacryloyloxyethyl phosphorylcholine) (PMPC), i...

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Project (1)
Project
We used from small molecules to polymers, all of them take amounts of charges to achieve hydration lubrication for applications in area biomedical science, mechanical science, and medical devices.