Yirupaiahgari KS Viswanath

Yirupaiahgari KS Viswanath
South Tees Hospitals NHS Foundation Trust · Tertiary Upper GI, Laparoscopic and Endoscopy Unit

MBBS, MS, FRCS (Glas.), FRCSI, FRCS(Gen.Surg.)

About

208
Publications
28,682
Reads
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1,801
Citations
Additional affiliations
October 2018 - October 2021
South Tees Hospitals NHS Foundation Trust
Position
  • Chair
September 2018 - present
Teesside University
Position
  • Professor
September 2015 - present
Teesside University
Position
  • Managing Director
Description
  • Programme Director for post-doctoral MCh surgical specialities carrying 180 credits including dissertation; MCh surgical gastro and minimally invasive surgery, MCh General and Breast Oncoplasty, MCh Endovascular surgery

Publications

Publications (208)
Article
Full-text available
Gastroesophageal reflux disease (GERD) is a common condition affecting more than 30% of the western adult population. Its impact on the quality of life is a well-known entity especially in patients with moderate to severe GERD. In the long term, it can lead to Barrett’s metaplasia, dysplasia, and adenocarcinoma. The ‘triad of intrinsic lower esoph...
Article
Full-text available
on behalf of the Oesophagogastric Anastomosis Audit collaborative Objective: This Delphi exercise aimed to gather consensus surrounding risk factors, diagnosis, and management of chyle leaks after esophagectomy and to develop recommendations for clinical practice. Background: Chyle leaks following esophagectomy for malignancy are uncommon. Although...
Article
Abstract Background Laparoscopic surgery has almost replaced open surgery in many areas of Gastro-Intestinal (GI) surgery. There is currently no published expert consensus statement on the principles of laparoscopic GI surgery. This may have affected the training of new surgeons. This exercise aimed to achieve an expert consensus on important prin...
Article
Full-text available
AbstractAim: The SARS-CoV- 2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.Methods: This was an international prospective cohort study of consecutive colorectal cancer...
Article
Background Health care workers, including surgical professionals, experienced psychological burnout and physical harm during the coronavirus 2019 pandemic. This global survey investigated the coronavirus 2019 pandemic impact on psychological and physical health. Methods We conducted a global cross-sectional survey between February 18, 2021 and Mar...
Article
Background Gastric cancer (GC) is the 5th most common malignancy and remains one of the major causes of worldwide cancer-related deaths. COVID-19 pandemic has had a significant impact on the provision of cancer care. This study aims to overview the global standpoint of gastric cancer patients (GCP) during the first year of the pandemic. Methods Th...
Article
Background Radical oesophagectomy is the recognized standard curative surgery for operable oesophageal cancers. Postoperative morbidity and mortality are considerable following open oesophagectomy. Minimally invasive techniques- (thoraco-laparoscopy and robotic surgery) has evolved as an alternative for open techniques. Oncological outcomes, tumor...
Article
Background Laparoscopic hiatal hernia repair continues to suffer from high recurrence rates, which has prompted the use of mesh reinforcement by some surgeons. Use of mesh however remains controversial due to its association with complications such as erosion, fibrosis and oesophageal stenosis. Biosynthetic Poly-4-Hydroxybutyrate Phasix™ ST mesh is...
Article
Full-text available
Objectives Studies have demonstrated high rates of mortality in people with proximal femoral fracture and SARS-CoV-2, but there is limited published data on the factors that influence mortality for clinicians to make informed treatment decisions. This study aims to report the 30-day mortality associated with perioperative infection of patients unde...
Article
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Background: This study aimed to determine the impact of pulmonary complications on death after surgery both before and during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic.
Article
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There is little evidence around the potentially protective role of previous Bacillus Calmette-Guerin (BCG) vaccination on postoperative mortality in patients with perioperative SARS-CoV-2 vaccination. Prior BCG vaccination did not protect SARS-CoV-2 infected patients against postoperative pulmonary complications and 30-day mortality.
Conference Paper
Full-text available
Background Gastric cancer (GC) is the 5th most common malignancy and remains one of the major causes of worldwide cancer-related deaths. COVID-19 pandemic has had a significant impact on the provision of cancer care. This study aims to overview the global standpoint of gastric cancer patients (GCP) during the first year of pandemic (PY1).
Conference Paper
Full-text available
Laparoscopic hiatal hernia repair continues to suffer from high recurrence rates, which has prompted the use of mesh reinforcement by some surgeons However, use of mesh remains controversial due to associated complications such as erosion and oesophageal stenosis Biosynthetic Poly 4 Hydroxybutyrate Phasix ™ST mesh is an emerging technology which co...
Article
Full-text available
Background Surgery is the main modality of cure for solid cancers and was prioritised to continue during COVID-19 outbreaks. This study aimed to identify immediate areas for system strengthening by comparing the delivery of elective cancer surgery during the COVID-19 pandemic in periods of lockdown versus light restriction.
Article
Full-text available
Background: Surgery is the main modality of cure for solid cancers and was prioritised to continue during COVID-19 outbreaks. This study aimed to identify immediate areas for system strengthening by comparing the delivery of elective cancer surgery during the COVID-19 pandemic in periods of lockdown versus light restriction. Methods: This internati...
Article
Full-text available
Background RCS Eng, the Royal College of Surgeons of England, has published much information with regard to the consenting process. A majority of patients seek health information through online resources as well as discussing with the care givers. Therefore, it is necessary that online material is both of high quality and reliable for patients. We...
Article
Full-text available
Abstract Background Surgery is the primary treatment that can offer potential cure for gastric cancer, but is associated with significant risks. Identifying optimal surgical approaches should be based on comparing outcomes from well designed trials. Currently, trials report different outcomes, making synthesis of evidence difficult. To address this...
Article
Full-text available
Background Rectal prolapse is a life-altering problem and laparoscopic ventral mesh rectopexy (LVMR) is emerging as the surgical intervention of choice. However, the literature is ambiguous on its effect on bowel function and sparse as regards bladder and sexual function. The aim is to assess short-term functional outcomes following LVMR. Method A...
Article
Full-text available
Background No evidence currently exists characterising global outcomes following major cancer surgery, including esophageal cancer. Therefore, this study aimed to characterise impact of high income countries (HIC) versus low and middle income countries (LMIC) on the outcomes following esophagectomy for esophageal cancer. Method This international...
Article
Full-text available
Abstract Systematic review and meta-analysis of the impact of intra-operative ultrasound guided breast-conserving surgery in early breast cancer. Background: Breast Conservation (BCS) is the standard surgical procedure for early breast cancer. It is challenging for surgeons to achieve adequate excision of the lesion with clear margins and acceptabl...
Article
Full-text available
Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates an...
Article
Full-text available
Background/Aims: STRETTA improves the quality of life and reduces the need for anti-reflux medication in select patients, especially those with uncomplicated gastro-esophageal reflux disease (GERD). We aimed to review the outcomes of STRETTA in patients with medically refractory GERD, who had undergone previous gastric surgery. Methods: This was a...
Article
Full-text available
Peri‐operative SARS‐CoV‐2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS‐CoV‐2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Su...
Research Proposal
Full-text available
Dear colleague, We are all used to the acronym PROMS (patient-related outcome measures), as a tool to measure patient outcomes, moreover, with regret not many surveys been carried out to, assess DROMS, where 'D' stands for Doctor especially during the ongoing pandemic. With a lot of humility and proudness, attached is the 3-4 minute survey to capt...
Article
Aim This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic. Method This was an international cohort study of patients undergoing elective resection of colon or rectal cancer without preoperative suspicio...
Article
Abstract Background The Oesophago-Gastric Anastomosis Audit (OGAA) is an international collaborative group set up to study anastomotic leak outcomes after oesophagectomy for cancer. This Delphi study aimed to prioritize future research areas of unmet clinical need in RCTs to reduce anastomotic leaks. Methods A modified Delphi process was overse...
Article
Full-text available
Background: Surgical services are preparing to scale up in areas affected by COVID-19. This study aimed to evaluate the association between preoperative SARS-CoV-2 testing and postoperative pulmonary complications in patients undergoing elective cancer surgery. Methods: This international cohort study included adult patients undergoing elective sur...
Article
Full-text available
Muscle Tension Dysphonia (MTD) is a syndrome involving abnormal vocal cord behaviour due to increased tension of laryngeal musculature. It has a complex etiology, but gastroesophageal reflux disease (GERD) is implicated in up to half of cases. The authors present the first reported case of MTD being successfully treated using STRETTA, an endoscopic...
Article
Full-text available
Background: The Oesophago-Gastric Anastomosis Audit (OGAA) is an international collaborative group set up to study anastomotic leak outcomes after oesophagectomy for cancer. This Delphi study aimed to prioritize future research areas of unmet clinical need in RCTs to reduce anastomotic leaks. Methods: A modified Delphi process was overseen by the O...
Article
Full-text available
Aim The royal college of Surgeons’ Supported Decision-Making guidance details how patients should access information necessary to make clinical decisions alongside their medical team. As patients become more reliant on information found via the internet, it is important to ensure that there are suitable, validated, and appropriate resources. This s...
Article
Background The Oesophago-Gastric Anastomosis Audit (OGAA) is an international collaborative group set up to study anastomotic leak outcomes after oesophagectomy for cancer. This Delphi study aimed to prioritize future research areas of unmet clinical need in RCTs to reduce anastomotic leaks. Methods A modified Delphi process was overseen by the OGA...
Article
Objective: This study aimed to characterize rates and management of anastomotic leak (AL) and conduit necrosis (CN) after esophagectomy in an international cohort. Background: Outcomes in patients with anastomotic complications of esophagectomy are currently uncertain. Optimum strategies to manage AL/CN are unknown, and have not been assessed in a...
Article
Full-text available
Background Surgical services are preparing to scale up in areas affected by COVID-19. This study aimed to evaluate the association between preoperative SARS-CoV-2 testing and postoperative pulmonary complications in patients undergoing elective cancer surgery. Methods This international cohort study included adult patients undergoing elective surge...
Article
Full-text available
IntroductionObesity is a chronic disease due to excess fat storage, a genetic predisposition, and environmental contribution where surgery offers a viable treatment option. The surgical treatment of obesity in the elderly population (> 55 years) remains controversial.PurposeTo evaluate the safety and efficacy of laparoscopic sleeve gastrectomy (LSG...
Article
Full-text available
PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathw...
Article
Full-text available
Citation: YKS Viswanath and Edward J Nevins. "A Novel Endoscopic Assessment Score which Predicts Long Term Outcome Following Stretta; Early Results". EC Gastroenterology and Digestive System 7.10 (2020): 07-12. Abstract Background: Endoscopic anti-reflux radio-frequency therapy (STRETTA) is a NICE approved treatment for gastro-esophageal reflux
Article
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Keywords: Endoscopic ultrasound scan pancreatic cystic neoplasm FNAC A B S T R A C T Introduction: Pancreatic cancer is the sixth most common cause of death from cancer in the UK. Cystic pancreatic neoplasms are being recognized more with the increase in the use of the CT scan. EUS has been increasingly used to asses and identify lesions in the pan...
Article
Full-text available
The application of artificial intelligence (AI), especially machine learning or deep learning (DL), is advancing at a rapid pace. The need for increased accuracy at endoscopic visualisation of the gastrointestinal (GI) tract is also growing. Convolutional neural networks (CNNs) are one such model of DL, which have been used for endoscopic image ana...
Poster
Full-text available
Systematic Review of Online Patient Resources to Support Shared Decision Making for Laparoscopic Cholecystectomy
Conference Paper
Full-text available
ABSTRACT Aim breast conservative surgery (BCS) and oncoplastic procedures are becoming more and more popular, providing better aesthetic outcome but one of the main draw-back of these procedures is involvement of the margin and return to theatre, causing undesired economic and cosmetic outcome in addition to psychological burden on the patients. Fr...
Article
Full-text available
Background: Several guidelines to guide clinical practice among esophagogastric surgeons during the COVID-19 pandemic were produced. However, none provide reflection of current service provision. This international survey aimed to clarify the changes observed in esophageal and gastric cancer management and surgery during the COVID-19 pandemic. Meth...
Article
Full-text available
Background The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods This inte...
Article
Full-text available
Summary Background The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods Th...
Article
Full-text available
Background: Late stage diagnosis of oesophageal and gastric cancer is common, which limits treatment options and contributes to poor survival. Aim: To explore patients' understanding, experience and presentation of symptoms before a diagnosis of oesophageal or gastric cancer. Design & setting: Between May 2016 and October 2017, all patients ne...
Article
Full-text available
Background: Bariatric surgery is an effective treatment for obesity and the associated comorbidities but carries a number of important risks. The Royal College of Surgeons advises patients to utilise online resources as part of the shared decision-making process. The aim of this study was to assess the quality of online materials on bariatric surg...
Article
Centralization of care has improved outcomes in esophagogastric (EG) cancer surgery. However, specialist surgical centers often work within clinical silos, with little transfer of knowledge and experience. Although variation exists in multiple dimensions of perioperative care, the differences in operative technique are rarely studied. An esophageal...
Conference Paper
Full-text available
Introduction: Detection of dysplasia at Barrett’s surveillance depends on a number of factors including: the endoscopist’s skill, use of advanced imaging (NBI, Acetic acid), adherence to Seattle protocol, and high-risk patient factors like male sex, smoking, length of Barrett’s segment and ednesday, October 23, 2019 Tuesday, October 22, 2019 y, Oct...
Article
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This report examines the quality of care received by patients admitted to hospital with a primary diagnosis of acute pancreatitis during the first 6 months of 2014. My first impression was that this report was a good news story, since a sizeable proportion of these patients received good care during a time when our daily press had started to regula...
Conference Paper
Full-text available
Background: Bariatric surgery is an effective treatment for obesity and the associated comorbidities but carries a number of important risks. The Royal College of Surgeon advises patients to utilize online resources as part of the shared decision making process. The aim of this study was to assess the quality of online materials on bariatric surger...
Article
Full-text available
Aims: AGR2 is a tissue-restricted member of the protein disulfide isomerase family that has attracted interest because it is highly expressed in a number of cancers, including gastroesophageal adenocarcinoma. The behavior of AGR2 was analyzed under oxidizing conditions, and an alkylation trapping and immunoprecipitation approach were developed to i...
Presentation
Full-text available
PTU-052 Table 1 "true" LGD (n=34) IND (n=13) (Downstaged cohort) NDBO (n=21) (Downstaged cohort) Mean age, years 66 71 69 Male sex 30/34 (88%) 12/13 (92%) 16/21 (76%) Median progression time to HGD/ IMC (months) 10(IQR,4-16) 19(IQR,11-28) 42(IQR 28-72) Median months of follow-up 17(IQR, 6-39) 31(IQR,15-46) 17(IQR,6-31) Conclusion Our data shows the...
Article
Full-text available
Background Late stage diagnosis of oesophageal and gastric cancer is common, limiting treatment options and contributing to poor survival. Aim To explore patient’s understanding, experience and presentation of symptoms prior to a diagnosis of oesophageal or gastric cancer. Design and Setting Between May 2016 and October 2017, all patients newly dia...
Article
Full-text available
BACKGROUND: Anastomotic leaks are associated with significant risk of morbidity, mortality and treatment costs after oesophagectomy. The aim of this study was to evaluate international variation in unit-level clinical practice and resource availability for the prevention and management of anastomotic leak following oesophagectomy. METHOD: The Oeso...
Conference Paper
Full-text available
Background Stretta® offers a therapeutic alternative for patients suffering from refractory gastro-oesophageal reflux disease (GORD). Current evidence suggests the treatment may improve symptoms of GORD and decrease requirement for proton pump inhibitor (PPI) therapy. This is the first UK study to evaluate outcomes after Stretta therapy with 2 year...
Conference Paper
Introduction Detection of dysplasia at Barrett’s surveillance depends on a number of factors - the endoscopist’s skill, use of advanced imaging, adherence to Seattle protocol, and high risk patient factors like male sex, smoking, length of Barrett’s segment and family history of oesophageal adenocarcinoma. Whether the high rates of dysplasia diagno...
Conference Paper
Full-text available
Interim outcome of open Lichtenstein inguinal hernia repair using self-adherent Adhesix® mesh; a prospective observational study
Conference Paper
Full-text available
Outcome of primary sublay ventral hernia repair using light weight PerFix™ Plug mesh: Prospective cohort study
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