Yingchao MengETH Zurich | ETH Zürich · Department of Chemistry and Applied Biosciences
Yingchao Meng
Dr. Sc.
About
29
Publications
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325
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Additional affiliations
September 2018 - April 2020
September 2016 - July 2018
July 2014 - June 2016
Education
September 2018 - September 2022
September 2016 - July 2018
August 2012 - July 2016
Publications
Publications (29)
The coating of filter media with silver is typically achieved by chemical deposition and aerosol processes. Whilst useful, such approaches struggle to provide uniform coating and are prone to blockage. To address these issues, an in situ method for coating glass fibers is presented via the dopamine‐mediated electroless metallization method, yieldin...
Iron oxide magnetic nanoparticles have emerged as promising theranostic agents for cardiovascular diseases. Using a multiscale approach, we investigate the interaction of 27 nm diameter multicore magnetite nanoflowers with blood components. Using flow cytometry and dynamic light scattering, we determine safe magnetite nanoflowers concentration leve...
Due to the differences in mechanical properties between cancer cells and their benign counterparts, the mechanical characteristics of cells have emerged as a significant feature in diagnosing cancer. Consequently, measuring cell deformability as a means of mechanical phenotyping is promising for both the detection and classification of the disease....
Small extracellular vesicles (sEVs; <200 nm) that contain lipids, nucleic acids, and proteins are considered promising biomarkers for a wide variety of diseases. Conventional methods for sEV isolation from blood are incompatible with routine clinical workflows, significantly hampering the utilization of blood-derived sEVs in clinical settings. Here...
Centrifugal microfluidic platforms aim to integrate and perform complex biological and chemical processes within disc-like substrates and valving through centrifugal forces and the Coriolis effect. Although the integration of active valves within such system can be used to enhance fluid control, the ability to fabricate and integrate addressable va...
Near-field optical manipulation has been widely used for guiding and trapping nanoscale objects close to an optical-active interface. This near-field manipulation opens opportunities for next-generation biosensing with the capability of large-area trapping and in situ detection. In this article, we used the finite element method (FEM) to analyze th...
The Extracellular RNA communication consortium (ERCC) is an NIH-funded program aiming to promote the development of new technologies, resources, and knowledge about exRNAs and their carriers. After Phase I (2013-2018), Phase 2 of the program (ERCC2, 2019-2023) aims to fill critical gaps in knowledge and technology to enable rigorous and reproducibl...
Since their discovery, CRISPR/Cas systems have been extensively exploited in nucleic acid biosensing. However, the vast majority of contemporary platforms offer only qualitative detection of nucleic acid, and fail to realize ultrasensitive quantitative detection. Herein, we report a digital droplet-based platform (DropCRISPR), which combines loop-m...
Colorimetric immunoassay is a widely used method for pathogen detection. The conventional implementation of immunoassays in 96-well plates often encounters difficulties for samples with low concentrations. In this study, the detection performance has been improved using a cellulose acetate membrane for target enrichment and immunodetection. For thi...
Rare-earth-doped upconversion nanoparticles (UCNPs) show great promise in a range of applications, including biological imaging and sensing, solar cells and security inks. Although their emission color can be tuned widely as a function of host matrix and dopant composition, the high dimensionality of the associated parameter space and the sensitivi...
Extracellular vesicles (EVs) play a critical role in the regulation of various biological processes and pathologies, and have significant utility as potential diagnostic biomarkers and drug delivery systems. That said, conventional methods for EV manipulation and analysis suffer from several drawbacks, including low yield and/or purity, complexity...
Lots of porous carbon materials, including boroncontaining carbon (BC) and isostatic pressure graphite (IG-110), are used in high-temperature gas cooled reactor (HTGR). To prevent corrosion caused by carbon-water reaction at high temperature, water absorbed in the materials needs to be removed before the reactor operation. It has become the consens...
压水堆核电站安全分析报告是核安全监管部门对其进行安全审查的重要文件,大破口失水事故是核电站运行的设计基准事故,是安全分析报告中的重要内容。本文使用RELAP5/MOD3.2进行压水堆冷管段大破口失水事故的计算,对比发现一回路冷管段发生双端断裂大破口时燃料元件包壳温度峰值(PCT)最高,且长时间维持在较高温度,此条件下反应堆最危险。计算结果表明,事故发生后,一回路压力迅速下降,堆芯冷却剂的流动性变差,导致堆芯裸露,燃料包壳温度又重新回升。通过安注系统和辅助给水系统等一系列动作,能保证燃料元件包壳温度不超过1204℃的限值。
The safety analysis report of the pressurized water reactor (PWR) nuclear power plant...
Carbonaceous dust can seriously affect the safe operation of high-temperature gas-cooled reactor (HTGR). Past researches have been focused on the physical generation mechanism which is mainly attributed to abrasion. However, discrepancies between actual observations and predictive models have been observed. To explain the observed discrepancies, ot...
Carbonaceous particles can pose serious threats to the safety of high temperature gas-cooled reactor (HTGR), and particle size distribution is one of the primary concerns for carbonaceous particles. Many researches have been conducted to study on the physical generation mechanism of carbonaceous particles in HTGR, which is mainly ascribed to abrasi...
A large number of carbon materials are adopted in high-temperature gas-cooled reactor (HTGR). These carbon materials mainly include graphite IG-110 and boron-containing carbon material (BC), both of which are typical porous materials and normally absorb moisture. In order to inhibit the chemical corrosion reaction between core internals materials a...
Carbonaceous dust can bring some potential threats to the safe operation of the high temperature gas-cooled reactor. Predictive models based on physical generation mechanism have produced errors in regards of actual observations. Thus, the chemical generation mechanism is worth investigating. This paper mainly analyzes the formation of carbonaceous...
高温气冷堆(High Temperature Gas-cooled Reactors,HTGRs)运行过程中会产生碳质粉尘,这些粉尘会对反应堆的运行安全带来不利影响。已有的研究主要集中在物理层面,但基于物理磨损得到的碳质粉尘产量与实际测量间存在较大误差。为解释测量到的误差并为反应堆的运行与设计提供指导,有必要对碳质粉尘的化学生成进行研究。在HTGRs运行过程,部分气体杂质在一定条件下可通过化学气相沉积(Chemical Vapor Deposition,CVD)的方式沉积析出碳质粉尘。本文将从实验和数值计算两方面对HTGRs内碳质粉尘的CVD生长开展研究。在实验方面,主要研究了H_2、CO、Ar气氛下,碳质粉尘在Inconel 617合金表面的CVD生长行为。研究表明,沉积后,基底表面的碳元...
To obtain size distribution of nanoparticles, scanning electron microscope (SEM) and transmission electron microscopy (TEM) have been widely adopted, but manual measurement of statistical size distributions from the SEM or TEM images is time-consuming and labor-intensive. Therefore, automatic detection methods are desirable. This paper proposes an...
Hall thrusters have been widely used in orbit correction and the station-keeping of geostationary satellites due to their high specific impulse, long life, and high reliability. During the operating life of a Hall thruster, high-energy ions will bombard the discharge channel and cause serious erosion. As time passes, this sputtering process will ch...
Drag-free flight has played a more and more important role in many space missions. The thrust control system is the key unit to achieve drag-free flight by providing a precise compensation for the disturbing force except gravity. The cusped field thruster has shown a significant potential to be capable of the function due to its long life, high eff...
The cusped field thruster is a new electric propulsion device that is expected to have a non-uniform radial current density at the anode. To further study the anode current density distribution, a multi-annulus anode is designed to directly measure the anode current density for the first time. The anode current density decreases sharply at larger r...
A new temperature measuring device based on thermoacoustic effect is designed to make up for the absence of passive temperature measuring device in the field of nuclear reactor, which is usually measured by thermocouples.The new device can improve the reliability and security of instrumentation,especially in harsh environment.By using the DeltaEC t...
The cusped field thruster is a newly emerging electric propulsion device. A radial non-uniformity of current density is supposed at the anode. To further study the anode current density distribution, a multi-annulus anode is designed to directly measure the anode current density for the first time. With the increase of the radial position, the anod...
The cusped field thruster is a kind of newly developed electric propulsion device. The electric field at the channel exit and the low frequency oscillation were measured by former experiments. While the formation mechanism of them have not been fully interpreted yet. Through studying two distinguishing typical electron paths in the thrusters, a flu...
多级会切磁场等离子推力器是一种新兴的电推进系统,各研究机构在过去的研究中均观察到该推力器电流密度存在径向分布的不均匀性,但尚为给出直接的实验验证。为了进一步研究多级会切磁场等离子推力器阳极区电子电流密度的分布状况,本文在国际上首次采用多环阳极的方式对阳极区电子电流密度进行了测量。研究结果表明,阳极区电子电流密度的分布具有不均匀性,且越靠近中心区域电子电流密度大幅度的提高,并发现阳极区电子电流密度的变化具有同时性,振幅同时增大或减小;实验还发现随着阳极电压的增加,中央通道电子电流密度相对值RCA逐渐增大,而且通气位置对电子电流的密度分布有一定的影响,实验结果对指导多级会切磁场等离子推力器阳极的设计和优化具有重要的指导意义。