Ying Wang

University of Shanghai for Science and Technology | USST · wang

Porcine deltacoronavirus (PDCoV) and transmissible gastroenteritis coronavirus (TGEV), the two causative agents of porcine diarrhea, have been reported to be at risk of cross-species transmission, including to humans. However, the potential host range in which these two CoVs interact remains unclear. We screened 16 animal counterparts for porcine a...

Objective: This study aimed to compare the efficacy of continuous perfusion of underwater bone grinding combined with a Y-shaped incision versus a microscopic posterior ear incision in the treatment of attic cholesteatoma. Study Design: Clinical trials were prospective studies from the Northern Jiangsu People’s Hospital. Research Object: Adult pati...

Coinfections with porcine circovirus types 2, 3, and 4 (PCV2, PCV3, and PCV4) are increasingly being detected in the swine industry. However, there is no commercially available vaccine which prevents coinfection with PCV2, PCV3, and PCV4. The development of a vaccine expressing capsid (Cap) fusion proteins of multiple PCVs represents a promising ap...

We successfully synthesized Ag nanowire/ZnO nanowall composite films with various morphologies using the water bath and polyol methods. These films combined the beneficial features of one-dimensional Ag nanowires and two-dimensional ZnO nanowalls. By altering the concentration of the growth solution, we successfully prepared ZnO nanowall/Ag nanowir...

Background Metabolic dysfunction-associated fatty liver disease (MAFLD) affects up to one-third of the global population. Since no approved pharmacotherapy for MAFLD is available, lifestyle modification remains the cornerstone of clinical care. Our study aims to evaluate the association of an overall healthy lifestyle with MAFLD risk. Methods We c...

Background: Cognitive impairment is the most common long‐term complication in children with congenital heart disease (CHD) and is closely related to the brain network. However, little is known about the impact of CHD on brain network organization. This study aims to investigate brain structural network properties that may underpin cognitive deficit...

Porcine epidemic diarrhea virus (PEDV) causes the third most important disease in the pig industry, after African swine fever and porcine reproductive and respiratory syndrome, and leads to illness or death of the entire litter, causing significant economic losses. In this study, three PEDV strains (HN-1, HN-2, and SC2023) were isolated from swine...

Combustion power generation is still the main way of lignite utilization, but lignite combustion will produce a lot of toxic gases, so how to make lignite clean utilization has become an urgent problem to be solved. Hydrogen is an environmentally friendly, zero-carbon emission clean energy because microorganisms can degrade brown coal to produce hy...

Pigeon Newcastle disease, caused by pigeon paramyxovirus type 1 (PPMV-1), is a significant infectious disease in pigeons that can result in substantial mortality and poses a severe threat to the pigeon industry. Rapid and accurate onsite diagnosis of pigeon disease is crucial for timely diagnosis and the implementation of effective prevention and c...

Aim: To identify the optimal first-line treatment for patients with extensive-stage small-cell lung cancer (ES-SCLC). Materials & methods: We conducted a network meta-analysis (CRD42023486863) to systematically evaluate the efficacy and safety of eight first-line treatment regimens for ES-SCLC, including 15 clinical trials. Results: Our analysis sh...

Crossover recombination is a hallmark of meiosis that holds the paternal and maternal chromosomes (homologs) together for their faithful segregation, while promoting genetic diversity of the progeny. The pattern of crossover is mainly controlled by the architecture of the meiotic chromosomes. Environmental factors, especially temperature, also play...

A double-layer broadband antireflective coating with remarkable optical performance and superhydrophilicity has been designed and prepared based on TiO2-SiO2 hybrid films. The synthesis of TiO2-SiO2 composite sols is carried out using titanium isopropoxide and tetraethyl orthosilicate as raw ingredients in an acid-catalyzed system. The TiO2-SiO2 hy...

Background Pyroptosis belongs to a unique type of programmed cell death among which GSDME is reported to exert anti-tumor immunity. However, the underlying mechanisms of how to boost tumor-infiltrating lymphocytes and whether it could benefit the efficacy of ICIs are still unknown. Methods CRC samples were used to analyze its relationship with CD8...

Porcine circovirus type 3 (PCV3) infection can cause symptoms similar to those of porcine circovirus type 2 (PCV2) infection, and coinfections with both PCV2 and PCV3 are observed in the swine industry. Consequently, developing chimeric vaccines is essential to prevent and control porcine circovirus infections. In this study, we used both E. coli a...

Existing research extensively incorporates syntactic information, especially dependency trees, to enhance the performance of relation extraction tasks. However, relying solely on dependency information may not fully exploit the rich semantic and syntactic information contained in sentences, and not all information in dependency trees is substantive...

Porcine circovirus disease (PCV) causes substantial economic losses in the pig industry, primarily from porcine circovirus type 2 (PCV2) and porcine circovirus type 3 (PCV3). Novel vaccines are necessary to prevent and control PCV infections. PCV coat proteins are crucial for eliciting immunogenic proteins that induce the production of antibodies a...

In this study, the rolling process of the warm-rolled duplex-phase Mg–8.3Li–3.1Al–1.09Si alloy and the strengthening mechanism of as-rolled Mg–Li alloy were investigated. The highest ultimate tensile strength (UTS, 323.66 ± 19.89 MPa) could be obtained using a three-pass rolling process with a 30% thickness reduction for each pass at 553 K. The str...

Impurity doping is a necessary technology for the application of semiconductor materials in microelectronic devices. The quantification of doping effects is crucial for controlling the transport properties of semiconductors. Here, taking two-dimensional (2D) hexagonal boron phosphide semiconductor as an example, we employ coherent potential approxi...

A double-layer broadband antireflection (AR) coating with excellent transmittance at 250–400 nm has been designed and prepared by the sol-gel method. The quarter-half double-layer structure is optimized with the aid of Filmstar thin film design software. Mesoporous SiO 2 film templated by an ethylene oxide-propylene oxide-ethylene oxide triblock co...

Background Brain metastasis is one of the main causes of recurrence and death in non-small cell lung cancer (NSCLC). Although radiotherapy is the main local therapy for brain metastasis, it is inevitable that some cancer cells become resistant to radiation. Microglia, as macrophages colonized in the brain, play an important role in the tumor microe...

Catalytic hydrogenation of carbon dioxide (CO2) for the preparation of higher carboxylic acids is attractive and promising. Herein, we demonstrate a general strategy for producing higher carboxylic acids via reaction of CO2 and H2 with light (C2~C4) oxygenates such as ketones, alcohols, polyols, ethers and epoxides. In a green solvent consisting of...

As recurrent and metastatic nasopharyngeal carcinoma (NPC) is the most common cause of death among patients with NPC, there is an urgent clinical need for the development of precision diagnosis to guide personalized treatment. Recent emerging evidence substantiates the increased expression of transferrin receptor 1 (also known as cluster of differe...

Recent study evidence the traditional Chinese medicinal (TCM) plant-derived schaftoside shows promise as a potential drug candidate for COVID-19 treatment. However, the biosynthetic pathway of schaftoside in TCM plants remains unknown. In this study, the genome of the TCM herb Grona styracifolia (Osbeck) H.Ohashi & K.Ohashi (GSO), which is rich in...

In recent years, with the increased usage of tumour necrosis factor (TNF) inhibitors, more side effects have been revealed. Paradoxical psoriasis, including psoriasis vulgaris, palmoplantar pustulosis, scalp psoriasis and their combinations, is a common adverse effect. However, erythrodermic psoriasis associated with alopecia due to anti-TNF-α is r...

The clinical impact of site-specific perineural invasion (PNI) in prostate cancer remains poorly understood. We compared radical prostatectomy findings and oncologic outcomes in 434 patients with single-site PNI on systematic sextant biopsy. PNI was present in the right apex (n = 62; 14%), right mid (n = 70; 16%), right base (n = 89; 21%), left ape...

Cheap Ni catalysts are highly active for the catalytic conversion of biomass, but it is challenging to prepare Ni-based catalysts with high selectivity and stability under mild conditions. Adjusting the adsorption strength of Ni catalysts to reaction substrates and intermediates by metal introduction is an effective strategy to achieve high yields...

Lithium‐selenium (Li−Se) batteries are promising energy storage devices. However, the long‐term durability and high‐rate performance of the Se cathode have been limited by significant volume expansion and the troublesome shuttle effect of polyselenides during repeated charging/discharging processes. To revolutionize these issues, we applied a top‐d...

To study the effect of various extractants on the structure of peat humic acid, peat humic acid was extracted using NH3·H2O, Na2CO3, NaHCO3, and Na2SO3 via alkali-extraction and acid-precipitation methods. The extracted peat humic acid was characterized using ultraviolet−visible (UV-vis) spectroscopy, Fourier transform infrared (FT-IR) spectroscopy...

Riemerella anatipestifer, belonging to Weeksellaceae family Riemerella, is a bacterium that can infect ducks, geese, and turkeys, causing diseases known as duck infectious serositis, new duck disease, and duck septicemia. We collected diseased materials from ducks on a duck farm in China and then isolated and purified a strain of serotype 1 R. anat...

Background To investigate whether CT-based radiomics can effectively differentiate between heterotopic pancreas (HP) and gastrointestinal stromal tumor (GIST), and whether different resampling methods can affect the model’s performance. Methods Multi-phase CT radiological data were retrospectively collected from 94 patients. Of these, 40 with HP a...

Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most important pathogens affecting the swine industry. In this report, a novel PRRSV strain SXht2012 was isolated from Shanxi province in China. To identify genetic characteristics of SXht2012, we conducted phylogenetic and homology analyses after sequencing its complete geno...

Pet golden hamsters were first identified being infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant of concern (VOC) and transmitted the virus back to humans in Hong Kong in January 2022. Here, we studied the binding of two hamster (golden hamster and Chinese hamster) angiotensin-converting enzyme 2 (ACE2) p...

Background Our primary objective was to assess the association between joint exposure to various air pollutants and the risk of ischemic stroke (IS) and the modification of the genetic susceptibility. Methods This observational cohort study included 307 304 British participants from the United Kingdom Biobank, who were stroke-free and possessed co...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes a variety of clinical manifestations, many of which originate from altered immune responses, either locally or systemically. Immune cell cross-talk occurs mainly in lymphoid organs. However, systemic cell interaction specific to coronavirus disease 2019 has not been well...

Flexible broadband photodetectors are desired but challenging to be fabricated for next‐generation wearable intelligent optoelectronic devices. Considering the narrow bandgap and strong light absorption, molybdenum telluride (MoTe2) based photoelectrochemical photodetectors are successfully assembled by liquid phase exfoliation accompanied with the...

Under the target of ‘emission peak and carbon neutrality’, electricity distribution networks will massively access low‐carbon technologies, which will result in problems such as insufficient hosting capacity, unbalanced electricity loads, degraded power quality etc. The low‐voltage flexible distribution network (LVFDN), which interconnects its low‐...

Background Neurofibrillary tangles (NFTs) are one of the most common pathological characteristics of Alzheimer’s disease. The NFTs are mainly composed of hyperphosphorylated microtubule-associated tau. Thus, recombinant tau is urgently required for the study of its fibrillogenesis and its associated cytotoxicity. Methods and results Heterologous e...

Sodium‐ion batteries (SIBs) and sodium‐ion capacitors (SICs) are promising candidates for cost‐effective and large‐scale energy storage devices. However, sluggish kinetics and low capacity of traditional anode materials inhibit their practical applications. Herein, a novel design featuring a layer‐expanded MoS2 is presented that dual‐reinforced by...

Overcoming hepatitis B virus (HBV) is a challenging problem because HBV deceives the host immune system. We have found that DENN domain-containing 2A (DENND2A) was essential for HBV maintenance, although its role remains unclear. In this study, we elucidate its function by screening a novel DENND2A-binding peptide, DENP4-3S. DENP4-3S exhibits homol...

Histone post-translational modifications, such as phosphorylation, methylation, acetylation, and ubiquitination, play vital roles in various chromatin-based cellular processes. Meiosis is crucial for organisms that depend on sexual reproduction to produce haploid gametes, during which chromatin undergoes intricate conformational changes. An increas...