Yigit Duzkoylu

• Gastroenterological Surgery at Turkiye Yuksek Ihtisas Education and Research Hospital, Ankara, Turkey

Endoscopic retrograde cholangiopancreatography (ERCP) is an interventional procedure that is often performed under sedation anesthesia and that is used in the diagnosis and treatment of hepatopancreaticobiliary diseases. The objective of this study was to compare the efficacy of hypnosis in conjunction with sedoanalgesia and sedoanalgesia alone in...

Enteric duplication cysts (EDCs) are infrequent intraabdominal lesions, though they can be detected anywhere throughout the gastrointestinal tract. Rarely, they can be asymptomatic and encountered in adulthood. Completely isolated EDCs are rarer with malignant transformation inside the cyst. Herein, we report a unique case of a mucinous neoplasm th...

Background and aims: Obesity, metabolic syndrome, and hyperlipidemia are known as risk factors for colorectal tumors. Colorectal polyps are accepted as potential precursors of colorectal cancer (CRC). This study was designed to clarify the association between the levels of serum lipids and the presence of colorectal polyps. Methods: This study was...

OBJECTIVE Colorectal cancer is one of the most common malignancies. Survival rates are directly related to the stage of cancer at the time of diagnosis, emphasizing the value of early diagnosis. Positron emission tomography with 18F-fluorodeoxyglucose is the gold standard imaging technique in staging, monitoring after treatment, and follow-up. We a...

Background and aim Acute pancreatitis is a common inflammation of the pancreas which can be severe and even potentially mortal. High rates of mortality showed the importance of immediate identification of patients at high risk and led the clinicians to refer to various scoring systems. Our aim was to investigate a clinical predictive model using th...

Inguinal and incisional hernias are the two most common types of hernias caused by abdominal wall weakness and defects in connective tissue. The structure of the extracellular matrix, mainly collagen and metalloproteinases (MMPs), and their regulators have been studied extensively and found to play a significant role in the pathophysiology of herni...

Background: Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) are the most common primary malignancies of the liver. The combined form of these two tumors (i.e., cHC-CC) is a considerably rare type of liver cancer displaying both malignant components. Objectives: The present study aimed to explore the factors affecting survival in patients...

Hydatid disease, mostly caused by Echinococcus granulosus, is a common parasitic infestation of the liver. In this type of infectious disease, humans are an intermediate host. Although most common sites are liver (70%) and lungs (25%), this parasitic tapeworm can be seen at any region of the body. Intraperitoneal cysts are usually secondary to the...

Giriş ve Amaç: Bu çalışmanın amacı canlıdan karaciğer transplantasyonunda greftin değerlendirilmesinde bilgisayarlı tomografi ile ölçülen tahmini greft volümünden korreksiyon faktörü kullanılarak hesaplanan tahmini greft ağırlığı ile gerçek greft ağırlığının karşılaştırılması ve bu korreksiyon faktörünün efektivitesinin araştırılmasıdır. Gereç ve Y...

ÖZET Amaç: Hekimler tarafından talep edilen laboratuvar analizlerinde, farklı tiplerde ve yüksek miktarda kan örneği toplanır. Bu çalışmanın amacı hospitalize hastalarda flebotomi ile kan kaybının miktarını ve hastaların Hb düzeylerine etkisini belirlemektir. Gereç ve Yöntem: Bir eğitim ve araştırma hastanesinin iç hastalıkları ve genel cerrahi kli...

Preoperative prediction of pancreatic fistula using computerized tomography

Pancreaticoduodenectomy is the gold standard treatment of neoplastic lesions of periampullary region. It is a well-known fact that postoperative pancreatic fistula is considered as the most common cause of morbidity. We aimed to present a novel technique using preoperative computed tomography (CT) evaluating the ratio of fatty volume to total pancr...

Background and Objectives The self-expandable metal stent (SEMS) is an alternative for several possible surgical and palliative treatments of upper gastrointestinal obstructions that occur in several disease states. The present study was performed to describe a single-center experience with upper gastrointestinal stents. Methods All patients at a...

Introduction Appendectomy is still the most commonly performed intra-abdominal operation worldwide. Interestingly, it has not reached the same popularity as other laparoscopic surgical procedures. Although multiple techniques have been described, a standard approach has not been described for the laparoscopic technique yet. Aim To perform hybrid a...

Introduction: Endoscopic retrograde cholangiopancreatography (ERCP) with sphincterotomy is the first step treatment modality of choledocholithiasis. In spite of an extended sphincterotomy, 10–15% of complex choledochal stones (larger than 15 mm and/or more than 3 stones) cannot be removed and recurrent ERCP procedures may be needed. Aim: To evaluat...

Background Hundreds of thousands of people have fled to Turkey since the civil war started in Syria in 2011. Refugees and local residents have been facing various challenges such as sociocultural and economic ones and access to health services. Trauma exposure is one of the most important and underestimated health problems of refugees settling in c...

Schwannomas are nevre sheath tumors originating from Schwann cells ( neural crest) of neural tissue and usually known to have benign behaviour. Although they are usually found on acoustic nevre or peripheral nerves, rarely they can be encountered in gastrointestinal system. Their colorectal presence is extremely rare. Diagnosis is made by immunohis...

Objective: Parathyroid allotransplantation is a new method for the treatment of permanent hypoparathyrodism. Adenoma cells are not used for transplantation because of the potential for functional or histopathologic transformation. In this study, we transplanted human adenomatous parathyroid cells to rabbits. Material and Methods: Parathyroid adenom...

Objective: Iatrogenic colonic perforation is a well-known complication that can increase mortality and morbidity in patients undergoing colonoscopy. A closer follow-up and well-planned treatment strategy are required when perforation as a complication arises. The aims of this study are to: (1) report the experience with a large colonoscopy series (...

zet Hemanjiyomlar karaciğerin en sık benign lezyonları olup vasküler dokudan köken alırlar ve genellikle asemptomatik davranırlar. Sıklıkla küçük boyutlarda olup kadınlarda ve orta yaş kesiminde sık görülürler. 'Dev' olarak adlandırılan hemanjiyomlar daha nadir izlenmekle birlikte genellikle semptomatik olurlar ve takip-tedavi seçimi lokalizasyon,...

Oral presentation

A Morgagni’s hernia is a congenital defect found in the anterior aspect of the diaphragmbetween the costal and the sternal portions of this muscle. This defect is also referred to as the space of Larrey. It has been reported that 70% of patients with Morgagni’s hernia are female, 90% of the hernias are right-sided, and 92%of the hernias have hernia...

Objective: We aimed to evaluate the efficacy of dilutional washing with saline solution following the administration of contrast agent for ERCP in decreasing the rate of pancreatitis, in our experimental rat model. Methods: Fourty Wistar-Albino® male rats of 250-300 g were divided into 4 equal groups. Group 1: Cannulation, Group 2: Cannulation+sali...

Aim. Although inguinal hernia repair is the most frequently performed surgical procedure in the world, the best repair method has not gained acceptance yet. The ideal repair must be safe, simple, and easy to perform and require minimal dissection which provides enough exploration, maintain patient’s comfort in the early stage, and also be cost-effe...

The Wnt pathway alterations have been identified in colorectal and many other cancer types. It has been reported that galectin-3 (which is encoded by the LGALS3 gene) alters the signaling mechanism in the Wnt/ β-catenin pathway by binding to β-catenin in colon and other cancers. AXIN1 is mainly responsible for the assembly of the β-catenin destruct...

A number of nontraumatic acute abdomen can result in peritonitis leading to sepsis. In emergent conditions, various procedures like segmentary colectomy and/or subtotal colectomy with anastomosis, Hartmann’s procedure, transverse colectomy, and/or expandable metallic stent (SEMS) placement can be performed, considering the status of the patient and...

Currently, type 2 diabetes mellitus (T2DM) is considered as a gastrointestinal disease. Numerous studies have demonstrated that bariatric operations ameliorate T2DM significantly. The laparoscopic Roux-en-Y gastric bypass (L-RYGB) is considered as the gold standard procedure. We aimed to evaluate the feasibility and impact of L-RYGB with ileal tran...

In recent years, with improvements in genotyping, a possible relationship between obesity-related gene polymorphisms and colorectal cancer (CRC) has been studied. The promoter region C-420G of the resistin gene is believed to have an important role in the development of malignancy. We prospectively evaluated the possible effect of the resistin C-42...

Meckel’s diverticulum is the most common congenital anomaly of the gastrointestinal tract. In this report, we aimed to represent a case of intestinal perforation, caused by double Meckel’s diverticulum, which is a very rare entity in surgical practice. The patient was a 20-year-old Caucasian man, admitted to hospital with complaints of abdominal pa...

Duplication of the gallbladder is a rare congenital anomaly of the gallbladder, with an estimated prevalence of 1–3 per 3800 individuals. Unless properly diagnosed preoperatively, it can lead to biliary tract injuries and postoperative complications which may require reoperative surgeries. While previously reported cases have been treated with conv...

Background: Colorectal cancer (CRC) is the third most frequent cancer worldwide. Research has revealed the contributions of the immune system and anti-inflammatory pathways in the development of cancer. The balance between cluster of differentiation 28 (CD28) and cytotoxic Tlymphocyte- associated protein 4 (CTLA4) signaling is important for the reg...

Background Incisional hernia is a complication that is encountered with a rate of 2–11 % and can lead to morbidity, work loss, and even mortality. Prosthetic materials that are used in hernia repair are still being tested, and the ideal one has not been proposed yet. While the recurrence rates with primary repair are found to be 30–50 %, these rate...

Epidermal growth factor (EGF) induces various biological signaling pathways, including proliferation and differentiation and it is the natural ligand of the epidermal growth factor receptor (EGFR) which is a member of tyrosine kinase transmembrane receptor family. EGF and EGFR control important processes in carcinogenesis and several differences in...

Objective: Gallbladder carcinomas are rare and aggressive neoplasms. They are usually advanced at the time of diagnosis. We aimed to evaluate incidental gallbladder cancers in our clinic, in terms of patients' demographics, diagnosis, treatment and follow-up, and compared our results with the literature. Material and methods: Patients who underw...

Acute cholecystitis is the most common complication of gallbladder stones. Today, Tokyo guidelines criteria are recommended for diagnosis, grading, and management of acute cholecystitis. We aimed to evaluate the levels of C-reactive protein (CRP) at different cut-off values to predict the severity of the disease and its possible role in grading the...

Giriş Periampüller bölge kanserleri, gastrointestinal siste-min en ölümcül kanserleri olarak kabul edilir. Bunun sebeplerinden bazıları bu tip kanserlerin erken ve hızlı yayılımı, geç tanı alması ve tam bir sistemik tedavinin henüz belirlenememiş olmasıdır. Pankreatikoduode-nektomi, diğer adıyla Whipple prosedürü, rezektabl periampuller bölge tümör...

Endometriosis is a common disesase among women of reproductive age, especially those with chronic abdominal pain. It is described as the the presence of functional ectopic endometrial tissue outside the uterus. Role of medical therapy is limited. Laparoscopic surgery is the gold standard today, for the diagnosis and treatment. Here, we aimed to rep...

Adnexal torsion in one of the most common etiologic factors of acute abdominal pain, especially in adolescent females. Auto-amputation of the adnexa is a rare and serious complication of torsion, resulting from devascularization, followed by detachment. This entity can be encountered incidentally during an emergent operation for acute appendicitis....

Lemmel's syndrome refers to extraluminal outpouchings of the duodenum in the periampullary region. Becase of the fact that it is a rare entity, it usually leads to misdiagnosis of extrahepatic cholestasis, especially in elderly patients. Although it has been treated with conventional surgical methods earlier, with the latest developments in endosco...

Gallstone disease is one of the most common surgical pathologies. Choledocholithiasis may occur in some of these cases and require surgical intervention. Although there are relatively non-invasive procedures such as endoscopic retrograde cholangiopancreatography (ERCP), this technique is usually unsuccessful in patients with stones larger than 10 m...

Aim: Is it necessary to obtain gastric biopsies from every patient undergoing gastroscopy whose their results from gastric endoscopy is "normal gastroscopy" Materials and Methods: This study includes 2486 patients referring to endoscopy unit with subtle GIS sypmtoms. All patients underwent standard upper gastrointestinal gastroscopy under conscious...

Mesenteric ischemia is one of the most mortal diseases of the gastrointestinal system causing acute abdomen. In most of the patients, the etiological factor is the obstructive embolism or thrombosis of superior mesenteric artery. In the literature, there have been reports regarding also celiac trunk occlusion in rare situations. The gold standard t...

Malignant phylloides breast tumor is a relatively rare and rapidly growing tumor of the breast. The incidence is less than 1% in all breast cancer population. These neoplasms are characterized by proliferation of mesenchymal and epithelial cells. The highest isk is between 35 and 45 years of age. The clinical presentation of phylloides tumor is het...

Peptic ulcer defines focal defects of submucosal tissue that might be seen in stomach but more frequently in duodenum. Increased secretion of acid is the main reason of duodenal ulcers while decreased defensive mechanism lies under the formation of gastric ulcers. Nonsteroidal anti-inflammatory drugs (NSAID) and Helicobacter Pylori infection are th...

AIM: Presentation of a very rare clinical coincidence MATERIAL-METHOD: A 61-year-old male patient admitted to a surgery clinic sufferıng from right inguinal pain and a mass which sometimes now and then descended down to his scrotum. He had those complaints for 5 years and explained that the mass was located outside extracorporeally but he could pus...

Benign cyts/tumors of the esophagus are usually asymptomatic and detected through endoscopic and radiologic procedures. When they are symptomatic, there is an indication of treatment and in the literature, it is advised to treat asymptomatic lesions to avoid possible complications. In this study, we aimed to revise our results in cases of benign es...

Aim. Although the mode of transmission of Helicobacter pylori (HP) infection is not completely clear, body fluids and personal contact seem to be key factors. Thus, the rate of infection in countries such as Turkey is much higher than in countries with bet-ter hygienic conditions. We have compared the long-term (5-year) effects of individual- and f...

Objective: Colorectal cancers are still among the most common causes of cancer-based deaths in all over the world, despite of the latest improvements in the diagnosis, treatment and screening methods. Tumors that are localized in the colorectal region can cause acute symptoms of obstruction that leads to the operations which have high rates of mort...

Background and Aims: Abdominal cocoon,also known as sclerosing encapsulating peritonitis, is a rare cause of intestinal obstruction usually diagnosed incidentally at laparotomy. the cause and pathogenesis of the condition have not been understood yet.We report our experience with five such adults. Methods: We describe five patients, presenting with...

Introduction About 70% of well-differentiated endocrine tumors arise from the gastrointestinal tract. Duodenal well-differentiated endocrine tumors account for only 2.6% of all neuroendocrine tumors. Following the first two case reports of somatostatin-secreting tumors in 1977, fewer than 200 cases of somatostatinoma have been reported. These tumor...

. Thyroidectomy creates a potential risk for all parathyroid glands and the recurrent laryngeal nerve (RLN). The identification and dissection of the RLN is the gold standard for preserving its function. In some cases, it may be quite difficult to identify the nerve localization. In such elusive locations, we aimed to identify RLNs using peroperati...

. Continuous ambulatory peritoneal dialysis (CAPD) is widely accepted for the management of end-stage renal disease (ESRD). Although not as widely used as hemodialysis, CAPD has clear advantages, especially those related to patient satisfaction and simplicity. Peritoneal dialysis (PD) catheter insertion can be accomplished by several different tech...

Amyloidosis refers to a variety of conditions in which amyloid proteins are abnormally deposited in organs and/or tissues. The most common forms of systemic amyloidosis are primary amyloidosis (PA) of light chains and secondary amyloidosis (SA) caused by chronic inflammatory diseases such as rheumatoid arthritis (RA). Although involvement of the th...

Aim This study was designed to compare the outcome of Ligasure hemorrhoidectomy and conventional 'closed' Ferguson's hemorrhoidectomy for grade III and IV hemorrhoids. Method A total of 82 consecutive patients with grade III or IV hemorrhoids were randomized to undergo Ligasure (42 patients) or Ferguson's (40 patients) hemorrhoidectomy. The operati...

Backgound: Despite of the high frequency of surgery for inguinal hernias, the effects of inguinal hernia repair type on testicular and sexual functions are unknown. Objective: Our objective was to determine whether one of the repair techniques (Moloney's darn and Lichtenstein) was associated with subsequent testicular function and sexuality. Design...

The groin hernia sac may contain various abdominal organs, such as the ovaries, the fallopian tubes, vermiform appendix and the urinary bladder which have been rarely reported. Here we report a case of a right sliding type inguinal hernia containing the ovary and the fallopian tube. The patient was a 32-year old woman, without any genital anomalies...