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I am a Ph.D. candidate focusing on the development and use of computational approaches in the neurobiology field. My research focus is gene regulation of nervous system development especially the evolution of neuronal differentiation. To understand nervous system development, I am mainly using multi-omic data analysis techniques such as scRNAseq, scATACseq, and ChIPseq by extensively usage of Linux (HPC clusters and bash scripting), R, and Python.
The ETS domain transcription factor family is one of the major transcription factor superfamilies that play regulatory roles in development, cell growth, and cancer progression. Although different functions of ETS member proteins in the nervous system have been demonstrated in various studies, their role in neuronal cell differentiation and the evo...
Multiple sclerosis (MS) is a demyelinating disorder that affects multiple regions of the central nervous system such as the brain, spinal cord, and optic nerves. Susceptibility to MS, as well as disease progression rates, displays marked patient-to-patient variability. To date, biomarkers that forecast differences in clinical phenotypes and outcome...
The ETS domain family of transcription factors is involved in a number of biological processes, and is commonly misregulated in various forms of cancer. Using microarray datasets from patients with different grades of glioma, we have analyzed the expression profiles of various ETS genes, and have identified ETV1, ELK3, ETV4, ELF4, and ETV6 as novel...