Yifan Huang

Yifan Huang
Chengdu University of Technology | CDUT · College of Earth Sciences

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102
Publications
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Introduction
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Publications

Publications (102)
Article
Objective: Brain-machine interfaces (BMIs) translate neural activity into motor commands to restore motor functions for people with paralysis. Local field potentials (LFPs) are promising for long-term BMIs, since the quality of the recording lasts longer than single neuronal spikes. Inferring neuronal spike activity from population activities such...
Article
Objectives: Brain-machine interfaces (BMIs) aim to help people with motor disabilities by interpreting brain signals into motor intentions using advanced signal processing methods. Currently, BMI users require intensive training to perform a pre-defined task, not to mention learning a new task. Thus, it is essential to understand neural informatio...
Article
Glycosylation is a post-translational modification involved in many important biological functions. The aberrant alteration of glycan structure is implicit with malfunction of cells and possess potential significance in medical diagnosis of complex diseases such as cancer. Liquid chromatography tandem mass spectrometry (LC-MS/MS) has been commonly...
Article
Glycosylation is known as a critical biological process that can largely affect the properties and the functions of proteins. Glycan isomers have been shown to be involved in a variety...
Article
Full-text available
Subtalar osteoarthritis (STOA) is often secondary to chronic ankle sprains, which seriously affects the quality of life of patients. Due to its etiology and pathogenesis was not studied equivocally yet, there is currently a lack of effective conservative treatments. Although they have been used for tissue repair, platelet-rich plasma-derived exosom...
Preprint
Full-text available
To solve the problems of instability and thermal stress birefringence of voltage divided medium in optical voltage sensor (OVS), a half-wave voltage regulation method based on a central symmetry electrode and an arbitrary directional electric field is proposed in this paper. The method uses a center-symmetric copper foil electrode or the ITO (Indiu...
Article
Full-text available
Glycoproteomics is a powerful yet analytically challenging research tool. Software packages aiding the interpretation of complex glycopeptide tandem mass spectra have appeared, but their relative performance remains untested. Conducted through the HUPO Human Glycoproteomics Initiative, this community study, comprising both developers and users of g...
Preprint
Full-text available
Subtalar osteoarthritis (STOA) is often secondary to chronic ankle sprains, which seriously affects the quality of life of patients. Due to its etiology and pathogenesis was not studied equivocally yet, there is currently a lack of effective conservative treatments. Although they have been used for tissue repair, platelet-rich plasma-derived exosom...
Article
Full-text available
Human and organizational factors (HOFs) play an important role in electric misoperation accidents (EMAs), but research into the reliability of human factors is still in its infancy in the field of EMAs, and further investment in research is urgently required. To analyze the HOFs in EMAs, a hybrid method including the Human Factors Analysis and Clas...
Article
Full-text available
Currently, surveillance strategies have inadequate performance for cirrhosis and early detection of hepatocellular carcinoma (HCC). The glycosylation of serum haptoglobin has shown to have significant differences between cirrhosis and HCC, thus can be used for diagnosis. We performed a comprehensive liquid chromatography—parallel reaction monitorin...
Article
Full-text available
Brain-machine interfaces (BMIs) help the disabled restore body functions by translating neural activity into digital commands to control external devices. Neural adaptation, where the brain signals change in response to external stimuli or movements, plays an important role in BMIs. When subjects purely use neural activity to brain-control a prosth...
Article
Full-text available
The emergence of COVID-19 pandemic has engaged the scientific community around the globe in the rapid development of effective therapeutics and vaccines. Owing to its crucial role in the invasion of the host cell, spike (S) glycoprotein is one of the major targets in these studies. The S1 subunit of the S protein (S1 protein) accommodates the recep...
Preprint
Full-text available
Brain-machine interfaces (BMIs) help the disabled restore body functions by translating neural activity into digital commands to control external devices. Neural adaptation, where the brain signals change in response to external stimuli or movements, plays an important role in BMIs. When subjects purely use neural activity to brain-control a prosth...
Article
Real-time wireless respiratory monitoring and biomarker analysis provide an attractive vision for noninvasive telemedicine such as the timely prevention of respiratory arrest or for early diagnoses of chronic diseases. Lightweight, wearable respiratory sensors are in high demand as they meet the requirement of portability in digital healthcare mana...
Article
Full-text available
The retention time provides critical information for glycan annotation and quantification from the Liquid Chromatography Mass Spectrometry (LC-MS) data. However, the variation of the precise retention time of glycans is highly dependent on the experimental conditions such as the specific separating columns, MS instruments and/or the buffer used. Th...
Article
Full-text available
Motor brain machine interfaces (BMIs) interpret neural activities from motor-related cortical areas in the brain into movement commands to control a prosthesis. As the subject adapts to control the neural prosthesis, the medial prefrontal cortex (mPFC), upstream of the primary motor cortex (M1), is heavily involved in reward-guided motor learning....
Preprint
Full-text available
Currently surveillance strategies have inadequate performance for the early detection of hepatocellular carcinoma (HCC). Protein glycosylation is a potential source of biomarkers to differentiate between cirrhosis and HCC. We performed a comprehensive LC-PRM-MS approach where a targeted parallel reaction monitoring (PRM) strategy was coupled to a p...
Article
Glycosylation is a ubiquitous and important post-translational modification, functioning as a critical role in many biological processes. Among all the monosaccharides, sialic acids are of utmost importance, due to their relatively high abundance and association with various diseases. Elucidation of linkage isomers on sialic acids remains challengi...
Preprint
Glycoproteome profiling (glycoproteomics) remains a considerable analytical challenge that hinders rapid progress in glycobiology. The complex tandem mass spectra generated from glycopeptide mixtures require sophisticated analysis pipelines for structural determination. Diverse informatics solutions aiding the process have appeared, but their relat...
Article
Full-text available
The clearance of myelin debris is a critical step in the functional recovery following spinal cord injury (SCI). As phagocytes do, microvascular endothelial cells (MECs) participate in myelin debris clearance at the injury site within one week. Our group has verified that G protein-coupled receptor kinase 2 interacting protein-1 (GIT1) is essential...
Article
Full-text available
Background: Bilateral decompression via unilateral approach (BDUA) is an effective surgical approach for treating lumbar degenerative diseases. However, no studies of prognosis, especially the recovery of the soft tissue, have reported using BDUA in an elderly population. The aims of these research were to investigate the early efficacy of the bil...
Article
Inspired by the powerful feature extraction and the data reconstruction ability of autoencoder, a stacked sparse denoising autoencoder is developed for electricity theft detection in this paper. The technical route is to employ the electricity data from honest users as the training samples, and the autoencoder can learn the effective features from...
Article
There are some significant defects in the existing optical current transducers (OCTs), such as optical power dependence, non-linear demodulation with Malus law, linear birefringence, etc. These defects severely hurt the reliability, stability, and accuracy of OCTs in long-term applications. The main idea to become free of these defects is to have a...
Article
Flexible strain sensors have potential applications in electronic skin, healthcare monitor, human-machine interface, and other fields. The key limitation of the strain sensor for human motion monitoring is to meet...
Article
Full-text available
In the above article [1] , in the second paragraph of Section II-A, the randomly selected low-pitch audio cue was 1.5 kHz (not 4 kHz). Thus, the article should state “the two-lever-press discrimination task trials were initialized by a high-pitch (10 kHz) or low-pitch (1.5 kHz) audio cue, which was randomly generated.”
Article
Chronic kidney disease results in high serum urea concentrations leading to excessive protein carbamylation, primarily albumin. This is associated with increased cardiovascular disease and mortality. Multiple methods were used to address whether carbamylation alters albumin metabolism. Intravital 2-photon imaging of the Munich Wistar Fromter (MWF)...
Article
Autonomous brain machine interfaces (BMIs) aim to enable paralyzed people to self-evaluate their movement intention to control external devices. Previous reinforcement learning (RL)-based decoders interpret the mapping between neural activity and movements using the external reward for well-trained subjects, and have not investigated the task learn...
Article
A mismatch between the expansion coefficients of carbon fiber (CF, T300) and resin causes thermal deterioration at the interface of composite cryotanks. This study presents an effective method to enhance the cryogenic interfacial properties of a T300/epoxy (EP) composite, in which graphene oxide (GO)/attapulgite (ATP) hierarchical structures are ch...
Article
Retention time is the most common and widely used criterion to report the separation of glycans using Liquid Chromatography (LC), but it varies widely across different columns, instruments and laboratories. This variation is problematic when inter-laboratory data is compared. Furthermore, it influences reproducibility and hampers efficient data int...
Article
Full-text available
Ischemia-reperfusion injury is the second most common injury of the spinal cord and has the risk of neurological dysfunction and paralysis, which can seriously affect patient quality of life. Salidroside (Sal) is an active ingredient extracted from Herba Cistanche with a variety of biological attributes such as antioxidant, antiapoptotic, and neuro...
Article
The directional rebound control of droplets is of great significance in many industrial applications, such as anti-icing, self-cleaning and microfluidics devices. Various strategies of droplets directional transport have been studied at room temperature and high temperature. However, it is still a challenge to control the rebound direction of dropl...
Conference Paper
Brain-machine interfaces (BMIs) translate neural signals into digital commands to control external devices. During the use of BMI, neurons may change their activity corresponding to the same stimuli or movement. The changes are represented by the neural tuning parameters which may change gradually and abruptly. Adaptive algorithms were proposed to...
Conference Paper
Reinforcement learning (RL) algorithm interprets neural signals into movement intentions with the guidance of the reward in Brain-machine interfaces (BMIs). Current RL algorithms generally work for the tasks with immediate rewards delivery, and lack of efficiency in delayed reward task. Prefrontal cortex, including medial prefrontal cortex(mPFC), h...
Article
Protein glycosylation is involved in many biological processes and physiological functions. Despite the recent advances in LC-MS/MS methodologies, the profiling of site-specific glycosylation is one of the major analytical challenges of glycoprotein analysis. Herein, we first reported the separation of glycopeptide isomers on porous graphitic carbo...
Article
As one of the major passive anti‐icing method, superhydrophobic surfaces have attracted extensive attentions to solve the icing problem. Self‐sensing properties of multifunctional superhydrophobic materials broaden the application prospects such as anti‐icing detection. Here, 1H ,1H ,2H ,2H ‐perfluorodecyltrichlorosilane (FDTS) modified graphene ba...
Preprint
Full-text available
Background: To investigate the early efficacy of the bilateral decompression via unilateral approach versus conventional approach transforaminal lumbar interbody fusion(TLIF)for the treatment of lumbar degenerative disc disease in the patients over 65 years of age, especially in the perioperative factors and the recovery of the soft tissue. Methods...
Preprint
Full-text available
Background: Bilateral decompression via unilateral approach(BDUA) is an effective surgical approach for treating lumbar degenerative diseases.However, no studies of prognosis, especially the recovery of the soft tissue, have reported using BDUA in an elderly population.The aims of these research were to investigate the early efficacy of the bilater...
Article
Transition metal dichalcogenides (TMDs) have gained intense interest for the outstanding optoelectronic, and electrochemical characteristics, utilized as versatile applications like gas sensors and photodetectors. However, TMDs based chemiresistors suffer from poor sensitivity at ppb-level detection and the experimental detection limit fails to rea...
Article
This study focuses on the influence of cryogenic temperature on the interface of carbon fiber reinforced plastics (CFRPs). Results of interfacial shear strength ( IFSS ) and mode II interlaminar fracture toughness ( G IIC ) at −196°C increased by 15.3% and 27.6% compared to the condition at room temperature (RT). By measuring the IFSS at −196°C, a...
Article
Here, high sensitivity gas sensing ink based on sulfonated rGO (S-rGO) decorated with SnS2 is synthesized for room temperature NO2 and NH3 detection. This sensing ink demonstrated an excellent sensitivity to ppb-level NO2 (17% response to 125ppb) and sub-ppm level NH3 (11% response to 1ppm). The unique absorption properties of SnS2 improve the sens...
Article
Increasing evidence has suggested that paracrine mechanisms might be involved in the underlying mechanism of mesenchymal stem cells (MSCs) transplantation, and exosomes are an important component of this paracrine role. However, MSCs are usually exposed to normoxia (21% O2) in vitro but experience large differences in oxygen concentration in the bo...
Article
Full-text available
Icing accretion on the surface of an aircraft not only increases the weight but also causes changes in the surface shape, so there is an urgent need for anti‐icing/deicing without shutdown. Here, a graphene‐based film with light weight, super‐hydrophobicity, high electric heat, and durability, which has both anti‐icing properties and electrothermal...
Article
Full-text available
Spinal cord injury (SCI) is a catastrophic disease which has complicated pathogenesis including inflammation, oxidative stress and glial scar formation. Astrocytes are the most abundant cells in central nervous system and fulfill homeostatic functions. Recent studies have described a new reactive phenotype of astrocytes, A1, induced by inflammation...
Article
Full-text available
Objectives: Osteogenesis is coupled with angiogenesis during bone remodelling. G-protein-coupled receptor (GPCR) kinase 2-interacting protein-1 (GIT1) is an important protein that participates in fracture healing by regulating angiogenesis. This study investigated whether GIT1 could affect bone mesenchymal stem cells (BMSCs) to secrete angiogenic...
Article
The prepared micro/nanoscale structure had a strong and flexible 2D graphene oxide (GO) component (elastic modulus 250 GPa) with a high aspect ratio of 1D nanocellulose (NCC), which possessed excellent mechanical properties (elastic modulus 150 GPa) and was a versatile material for enhancing epoxy (EP) nanocomposites. In this work, we had proposed...
Article
The optimization of electric field distributions in the optical voltage sensor (OVS) are mostly based on the finite element calculations and the exhaustive search method. It is unable to map complicated and nonlinear relationships between the electric field distribution and the sensing structure. Moreover, these methods turn out to be time-consumin...
Article
Nitrogen dioxide (NO2) is an important gas for industrial production, medical treatment and biology. At present, the detection of ultralow concentrations (ppb levels) of NO2 at low temperature in the presence of other interfering gases is still a great challenge. In this study, we developed nanohybrids of SnS2 and reduced graphene oxide (SnS2/rGO)...
Conference Paper
Cortical Local field potentials (LFPs) in primary motor cortex (M1) include significant movement information. As a movement decoding source, LFPs have the advantage of being long-lasting and stable. However, LFPs contain activity of neural ensemble from neighborhood or even distant cortical areas. Information fully relevant to the movement task is...
Article
Multifunctional surfaces with special wettability and sensing capabilities have attracted the interest of researchers because of their wide application prospects. Herein, based on octadecylamine (ODA) and carboxylic carbon nanotube (cCNT), a conductive composite coating (ODA/cCNT) with a micro-nanoscale hierarchical structure is fabricated by a sim...
Article
G protein-coupled receptor kinase 2 interacting protein-1 (GIT1) is a scaffold protein that plays a vital role in bone modeling and remodeling during osteogenesis coupled with angiogenesis. Recent studies have shown that a specialized subset of vascular endothelium strongly positive for CD31 and Endomucin (CD31 hi Emcn hi ) is coupled with anabolic...
Article
Glycosylation of proteins and lipids has been recently shown to play important biological roles, including cell signaling, adhesion motility, immune response, and pathogen interaction. Functions of many proteins are modulated through glycosylation. To better understand the biological attributes of glycans, reliable quantitative glycomics is needed....
Article
Introduction: Aberrant glycosylation has been associated with many diseases. Decades of research activities have reported many reliable glycan biomarkers of different diseases which enable effective disease diagnostics and prognostics. However, none of the glycan markers have been approved for clinical diagnosis. Thus, a review of these studies is...
Article
Protein glycosylation, an important post‐translational modification, plays an essential role in a wide range of biological processes such as immune response, intercellular signaling, inflammation, and host‐pathogen interaction. Aberrant glycosylation has been correlated with various diseases. However, studying protein glycosylation remains challeng...
Article
The diversification of the chemical properties and biological functions of proteins is attained through posttranslational modifications, such as glycosylation. Glycans, which are covalently attached to proteins, play a vital role in cell activities. The microheterogeneity and complexity of glycan structures associated with proteins make comprehensi...
Article
This paper presents a novel optical current transducer based on Newton’s ring sub-wavelength grating. It converts the Faraday rotation angle into synchronized rotation of the spot image and locates the spot with a four-quadrant detector to achieve real-time linear measurement of the current. The Newton’s ring grating is used instead of a radial gra...
Article
Full-text available
Protein glycosylation is a common protein post-translational modification (PTM) in living organisms and has been shown to associate with multiple diseases, and thus may potentially be a biomarker of such diseases. Efficient protein/glycoprotein extraction is a crucial step in the preparation of N-glycans derived from glycoproteins prior to LC-MS an...
Article
The aim of the paper is to develop a novel nanocomposite with high mechanical properties. The mechanical properties are improved by aligning the Fe 3 O 4 /multi-walled carbon nanotubes (MWCNTs) into a highly oriented manner in epoxy resin (EP) via a low magnetic field. Fe 3 O 4 nanoparticles were tethered onto the surface of MWCNTs by a novel water...
Article
This paper investigates the possibilities of optimizing the Pockels electric field in a transverse modulated optical voltage sensor with a spherical electrode structure. The simulations show that due to the edge effect and the electric field concentrations and distortions, the electric field distributions in the crystal are non-uniform. In this cas...